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  1. Article ; Online: Telemedicine: historical roots, basic concepts, and today's use.

    Actis, Giovanni C

    Minerva gastroenterology

    2021  Volume 68, Issue 1, Page(s) 1–3

    MeSH term(s) Telemedicine
    Language English
    Publishing date 2021-06-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062713-8
    ISSN 2724-5365
    ISSN (online) 2724-5365
    DOI 10.23736/S2724-5985.21.02933-8
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  2. Article ; Online: Helicobacter pylori infection and Parkinson's disease.

    Actis, Giovanni C

    Minerva gastroenterologica e dietologica

    2019  Volume 65, Issue 2, Page(s) 164–165

    MeSH term(s) Helicobacter Infections/complications ; Helicobacter pylori ; Humans ; Parkinson Disease/etiology
    Language English
    Publishing date 2019-02-11
    Publishing country Italy
    Document type Letter
    ZDB-ID 1077354-x
    ISSN 1827-1642 ; 1121-421X ; 0026-4776
    ISSN (online) 1827-1642
    ISSN 1121-421X ; 0026-4776
    DOI 10.23736/S1121-421X.19.02554-6
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  3. Article ; Online: Helicobacter pylori 2017: revitalized therapies for an ever-challenging bug.

    Actis, Giovanni C

    Panminerva medica

    2017  Volume 59, Issue 2, Page(s) 198

    MeSH term(s) Helicobacter Infections ; Helicobacter pylori ; Humans ; Stomach Neoplasms
    Language English
    Publishing date 2017-02-27
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 123572-2
    ISSN 1827-1898 ; 0031-0808
    ISSN (online) 1827-1898
    ISSN 0031-0808
    DOI 10.23736/S0031-0808.16.03284-5
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  4. Article ; Online: COVID vaccine's hot problems: erratic serious blood clotting, ill-defined prion-like reactogenicity of the spike, unclear roles of other factors.

    Actis, Giovanni C / Ribaldone, Davide G / Pellicano, Rinaldo

    Minerva medica

    2022  Volume 112, Issue 6, Page(s) 695–697

    MeSH term(s) Blood Coagulation Disorders/etiology ; COVID-19 Vaccines/adverse effects ; Humans
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-02-15
    Publishing country Italy
    Document type Editorial
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.21.07769-7
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  5. Article ; Online: Modulation of the gut microbiota: opportunities and regulatory aspects.

    Ribaldone, Davide G / Pellicano, Rinaldo / Fagoonee, Sharmila / Actis, Giovanni C

    Minerva gastroenterology

    2022  Volume 69, Issue 1, Page(s) 128–140

    Abstract: The human gut is an intensively colonized organ containing microorganisms that can be health-promoting or pathogenic. This feature led to the development of functional foods aiming to fortify the former category at the expense of the latter. Since long, ... ...

    Abstract The human gut is an intensively colonized organ containing microorganisms that can be health-promoting or pathogenic. This feature led to the development of functional foods aiming to fortify the former category at the expense of the latter. Since long, cultured products, including probiotics fortification, have been used for humans as live microbial feed additions. This review presents some of the microbes used as probiotics and discusses how supplementation with probiotics may help initiate and/or restore eubiotic composition of gut microbiota. Additionally, it considers safety and regulatory aspects of probiotics.
    MeSH term(s) Humans ; Gastrointestinal Microbiome ; Probiotics/therapeutic use
    Language English
    Publishing date 2022-02-18
    Publishing country Italy
    Document type Review ; Journal Article
    ZDB-ID 3062713-8
    ISSN 2724-5365
    ISSN (online) 2724-5365
    DOI 10.23736/S2724-5985.22.03152-7
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  6. Article ; Online: COVID-19 and the enteric system: rapidly propagating issues.

    Actis, Giovanni C / Pellicano, Rinaldo / Fagoonee, Sharmila / Ribaldone, Davide G

    Minerva medica

    2022  Volume 114, Issue 2, Page(s) 217–223

    Abstract: The newly described SARS-CoV-2 respiratory virus is now righteously presenting as an ominous threat, based on the speed with which it originated a zoonosis from bats; advancing at a similar rate, the virus has placed mankind before a pandemic, with an ... ...

    Abstract The newly described SARS-CoV-2 respiratory virus is now righteously presenting as an ominous threat, based on the speed with which it originated a zoonosis from bats; advancing at a similar rate, the virus has placed mankind before a pandemic, with an infection toll of some 431 million, and a lethality of 5,9 million (as of February 25, 2022). The size of the harm that this agent can unleash against us is appallingly wide, from brain ischemia to foot chilblain, passing by heart massive infarction. Designing a possible response, we reappraised the well-known equation depression-inflammation, and tested the hypothesis that an upgraded ease-of-mind might help reduce the host's hospitality towards SARS-CoV-2. With time passing, it becomes increasingly evident that the virus shall tend to progressively occupy spaces, replacing pandemics with an apparently calm endemicity. This will have to be avoided, and surveillance of society on psychological terms will be one tenet. Needless to say, the role of the enteric tract in these issues is growing higher, and it will be narrated to seal the matters with the last (not the least) touch of glue.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Inflammation
    Language English
    Publishing date 2022-03-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.22.08077-6
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  7. Article ; Online: Cyclosporine for severe steroid-refractory ulcerative colitis: commenting the comment.

    Actis, Giovanni C / Pellicano, Rinaldo

    Minerva gastroenterologica e dietologica

    2018  Volume 64, Issue 3, Page(s) 190–192

    MeSH term(s) Colitis, Ulcerative/drug therapy ; Cyclosporine/therapeutic use ; Gastrointestinal Agents/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Infliximab/therapeutic use
    Chemical Substances Gastrointestinal Agents ; Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D) ; Infliximab (B72HH48FLU)
    Language English
    Publishing date 2018-01-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1077354-x
    ISSN 1827-1642 ; 1121-421X ; 0026-4776
    ISSN (online) 1827-1642
    ISSN 1121-421X ; 0026-4776
    DOI 10.23736/S1121-421X.18.02462-5
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  8. Article ; Online: The gut microbiome.

    Actis, Giovanni C

    Inflammation & allergy drug targets

    2014  Volume 13, Issue 4, Page(s) 217–223

    Abstract: ... within a given microbiome: growth of adherent E. coli, of C. concisus, and of C. jejuni, might be examples of causes ...

    Abstract Since the discovery and use of the microscope in the 17(th) century, we know that we host trillions of micro-organisms mostly in the form of bacteria indwelling the "barrier organs" skin, gut, and airways. They exert regulatory functions, are in a continuous dialogue with the intestinal epithelia, influence energy handling, produce nutrients, and may cause diabetes and obesity. The human microbiome has developed by modulating or avoiding inflammatory responses; the host senses bacterial presence through cell surface sensors (the Toll-like receptors) as well as by refining mucous barriers as passive defense mechanisms. The cell density and composition of the microbiome are variable and multifactored. The way of delivery establishes the type of initial flora; use of antibiotics is another factor; diet composition after weaning will shape the adult's microbiome composition, depending on the subject's life-style. Short-chain fatty acids participate in the favoring action exerted by microbiome in the pathogenesis of type-2 diabetes and obesity. Clinical observation has pinpointed a sharp rise of various dysimmune conditions in the last decades, including IBD and rheumatoid arthritis, changes that outweigh the input of simple heritability. It is nowadays proposed that the microbiome, incapable to keep up with the changes of our life-style and feeding sources in the past few decades might have contributed to these immune imbalances, finding itself inadequate to handle the changed gut environment. Another pathway to pathology is the rise of directly pathogenic phyla within a given microbiome: growth of adherent E. coli, of C. concisus, and of C. jejuni, might be examples of causes of local enteropathy, whereas the genus Prevotella copri is now suspected to be linked to rise of arthritic disorders. Inflammasomes are required to shape a non colitogenic flora. Treatment of IBD and infectious enteritides by the use of fecal transplant is warranted by this knowledge.
    MeSH term(s) Animals ; Diet ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Gastrointestinal Tract/drug effects ; Gastrointestinal Tract/microbiology ; Humans ; Inflammation/drug therapy ; Inflammation/microbiology ; Intestinal Mucosa/microbiology ; Microbiota/physiology ; Obesity/microbiology ; Probiotics/pharmacology
    Language English
    Publishing date 2014-06-18
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2215862-5
    ISSN 2212-4055 ; 1871-5281
    ISSN (online) 2212-4055
    ISSN 1871-5281
    DOI 10.2174/1871528113666140623113221
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  9. Article ; Online: Chronic (inflammatory) diseases: precision medicine versus comprehensive understanding?

    Actis, Giovanni C / Pellicano, Rinaldo

    Minerva medica

    2017  Volume 109, Issue 2, Page(s) 150–151

    MeSH term(s) Chronic Disease ; Humans ; Inflammation/therapy ; Precision Medicine
    Language English
    Publishing date 2017-11-07
    Publishing country Italy
    Document type Letter
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.17.05444-1
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  10. Article ; Online: Co-morbid immunopathological affections in outpatients with inflammatory bowel disease: a prospective study.

    Actis, Giovanni C / Pellicano, Rinaldo

    Minerva gastroenterologica e dietologica

    2016  

    Language English
    Publishing date 2016-02-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1077354-x
    ISSN 1827-1642 ; 1121-421X ; 0026-4776
    ISSN (online) 1827-1642
    ISSN 1121-421X ; 0026-4776
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