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  1. Article ; Online: Navigating the landscape of medical triage: Unveiling the potential and challenges of large language models and beyond.

    Lansiaux, Edouard / Baron, Marc-Antoine / Vromant, Amélie

    The American journal of emergency medicine

    2024  Volume 78, Page(s) 224

    MeSH term(s) Humans ; Triage ; Language ; Emergency Service, Hospital
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2024.02.013
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    Zs.A 2005: Show issues Location:
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  2. Article ; Online: Overcoming limitations in out-of-hospital cardiac arrest extracorporeal cardiopulmonary resuscitation: optimizing assessment and patient selection for future clinical trials.

    Lansiaux, Edouard / Playe, Valentin / Jain, Nityanand

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Volume 24, Issue 9, Page(s) 602–603

    MeSH term(s) Humans ; Out-of-Hospital Cardiac Arrest/diagnosis ; Out-of-Hospital Cardiac Arrest/therapy ; Patient Selection ; Clinical Trials as Topic
    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001535
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  3. Article: The new face of monkeypox virus: an emerging global emergency.

    Jain, Nityanand / Lansiaux, Edouard / Simanis, Raimonds

    New microbes and new infections

    2022  Volume 47, Page(s) 100989

    Language English
    Publishing date 2022-05-27
    Publishing country England
    Document type Editorial
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2022.100989
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  4. Article ; Online: Beyond Traditional Pain Relief: A Review of Alternative Analgesics in Myocardial Infarction Patient Management.

    Chodnekar, Swarali Yatin / Jain, Nityanand / Lansiaux, Edouard / Panag, Deepkanwar Singh / Gibietis, Valdis

    Journal of pain & palliative care pharmacotherapy

    2024  , Page(s) 1–13

    Abstract: While morphine is the recommended first-line treatment for pain management in patients with acute coronary syndrome, recent studies have raised concerns about its association with adverse outcomes. Morphine has been found to cause delayed antiplatelet ... ...

    Abstract While morphine is the recommended first-line treatment for pain management in patients with acute coronary syndrome, recent studies have raised concerns about its association with adverse outcomes. Morphine has been found to cause delayed antiplatelet effects, decreased ticagrelor absorption, increased platelet reactivity, and compromised efficacy of dual antiplatelet therapy (DAPT). Alternative analgesics, such as lidocaine, fentanyl, and acetaminophen, have begun to emerge as viable alternatives, each with unique mechanisms and potential benefits. Lidocaine is demonstrated to have superior effects in reducing microvascular obstruction and fewer adverse events compared to fentanyl, despite being less effective in pain reduction. Fentanyl, which shows rapid onset and powerful analgesic properties, may interfere with ticagrelor absorption, potentially affecting platelet inhibition. Acetaminophen, a centrally acting analgesic, emerges as a safer alternative with comparable pain relief efficacy and minimal side effects. The results of multiple clinical trials emphasize the significance of customizing pain management approaches to match individual patient profiles and achieving the optimal balance between pain relief and potential adverse outcomes.
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2078852-6
    ISSN 1536-0539 ; 1536-0288
    ISSN (online) 1536-0539
    ISSN 1536-0288
    DOI 10.1080/15360288.2024.2304008
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  5. Article: Outbreaks of iatrogenic botulism in Europe: Combating off-label medical use of Botulinum Neurotoxin (BoNT) in bariatric procedures.

    Jain, Nityanand / Lansiaux, Edouard / Yucel, Umut / Huenermund, Swantje / Goeschl, Stella / Schlagenhauf, Patricia

    New microbes and new infections

    2023  Volume 53, Page(s) 101152

    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Editorial
    ZDB-ID 2750179-6
    ISSN 2052-2975
    ISSN 2052-2975
    DOI 10.1016/j.nmni.2023.101152
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  6. Article ; Online: The virology of human monkeypox virus (hMPXV): A brief overview.

    Lansiaux, Edouard / Jain, Nityanand / Laivacuma, Sniedze / Reinis, Aigars

    Virus research

    2022  Volume 322, Page(s) 198932

    Abstract: First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic pathogen closely associated with the smallpox virus. The virus usually spreads via close contact with the infected animal or human and has been endemic mostly in parts of ... ...

    Abstract First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic pathogen closely associated with the smallpox virus. The virus usually spreads via close contact with the infected animal or human and has been endemic mostly in parts of the African continent. However, with the recent increase in trade, tourism, and travel, the virus has caused outbreaks in countries outside Africa. The recent outbreak in 2022 has been puzzling given the lack of epidemiological connection and the possible sexual transmission of the virus. Furthermore, there is limited understanding of the structural and pathogenetic mechanisms that are employed by the virus to invade the host cells. Henceforth, it is critical to understand the working apparatus governing the viral-immune interactions to develop effective therapeutical and prophylactic modalities. Hence, in the present short communication, we summarize the previously reported research findings regarding the virology of the human monkeypox virus.
    MeSH term(s) Animals ; Humans ; Monkeypox virus/genetics ; Mpox (monkeypox)/epidemiology ; Variola virus ; Disease Outbreaks ; Africa
    Language English
    Publishing date 2022-09-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605780-9
    ISSN 1872-7492 ; 0168-1702
    ISSN (online) 1872-7492
    ISSN 0168-1702
    DOI 10.1016/j.virusres.2022.198932
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  7. Article: The virology of human monkeypox virus (hMPXV): A brief overview

    Lansiaux, Edouard / Jain, Nityanand / Laivacuma, Sniedze / Reinis, Aigars

    Virus research. 2022 Dec., v. 322

    2022  

    Abstract: First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic pathogen closely associated with the smallpox virus. The virus usually spreads via close contact with the infected animal or human and has been endemic mostly in parts of ... ...

    Abstract First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic pathogen closely associated with the smallpox virus. The virus usually spreads via close contact with the infected animal or human and has been endemic mostly in parts of the African continent. However, with the recent increase in trade, tourism, and travel, the virus has caused outbreaks in countries outside Africa. The recent outbreak in 2022 has been puzzling given the lack of epidemiological connection and the possible sexual transmission of the virus. Furthermore, there is limited understanding of the structural and pathogenetic mechanisms that are employed by the virus to invade the host cells. Henceforth, it is critical to understand the working apparatus governing the viral-immune interactions to develop effective therapeutical and prophylactic modalities. Hence, in the present short communication, we summarize the previously reported research findings regarding the virology of the human monkeypox virus.
    Keywords Monkeypox virus ; Variola virus ; humans ; pathogens ; research ; tourism ; trade ; travel ; virology ; viruses ; Africa
    Language English
    Dates of publication 2022-12
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 605780-9
    ISSN 1872-7492 ; 0168-1702
    ISSN (online) 1872-7492
    ISSN 0168-1702
    DOI 10.1016/j.virusres.2022.198932
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

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  8. Article: Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey.

    Lansiaux, Edouard / Jain, Nityanand / Yatin Chodnekar, Swarali / Siddiq, Abdelmomen / Ibrahim, Muiz / Yèche, Mathieu / Kantane, Inara

    Frontiers in physiology

    2024  Volume 15, Page(s) 1321468

    Abstract: Space travel exposes astronauts to several environmental challenges, including microgravity and radiation exposure. To overcome these stressors, the body undergoes various adaptations such as cardiovascular deconditioning, fluid shifts, metabolic changes, ...

    Abstract Space travel exposes astronauts to several environmental challenges, including microgravity and radiation exposure. To overcome these stressors, the body undergoes various adaptations such as cardiovascular deconditioning, fluid shifts, metabolic changes, and alterations in the state of the bone marrow. Another area of concern is the potential impact of these adaptations on erythrocyte and haemoglobin concentrations, which can lead to what is commonly referred to as space anaemia or microgravity-induced anaemia. It is known that anaemia may result in impaired physical and cognitive performance, making early detection and management crucial for the health and wellbeing of astronauts during extended space missions. However, the effects and mechanisms of space anaemia are not fully understood, and research is underway to determine the extent to which it poses a challenge to astronauts. Further research is needed to clarify the long-term effects of microgravity on the circulatory system and to investigate possible solutions to address spaceflight-induced anaemia. This article reviews the potential link between spaceflight and anaemia, based on existing evidence from simulated studies (e.g., microgravity and radiation studies) and findings from spaceflight studies (e.g., International Space Station and space shuttle missions).
    Language English
    Publishing date 2024-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2024.1321468
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  9. Article ; Online: War-induced obstetric emergencies necessitate improved global intervention.

    Mykolaivna, Nikitina Iryna / Ahmad, Amal Olabisi / Adebusoye, Favour Tope / Awuah, Wireko Andrew / Wellington, Jack / Tenkorang, Pearl Ohenawaa / Abdul-Rahman, Toufik / Lansiaux, Edouard

    Postgraduate medical journal

    2023  Volume 99, Issue 1176, Page(s) 1049–1051

    MeSH term(s) Pregnancy ; Female ; Humans ; Emergencies ; Obstetrics ; Cesarean Section
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1093/postmj/qgad048
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  10. Article ; Online: Beta-Thalassemia minor and SARS-CoV-2, prevalence, severity, morbidity and mortality: a systematic review study

    Lansiaux, Edouard / Drouin, Emmanuel / Bolm, Carsten

    medRxiv

    Abstract: Background: Since the first year of the COVID-19 global pandemic, a hypothesis concerning the possible protection/immunity of beta-thalassemia carriers remains in abeyance. Methods: Three databases (Pubmed Central, Scopus and Google Scholar) were ... ...

    Abstract Background: Since the first year of the COVID-19 global pandemic, a hypothesis concerning the possible protection/immunity of beta-thalassemia carriers remains in abeyance. Methods: Three databases (Pubmed Central, Scopus and Google Scholar) were screened and checked in order to extract all studies about incidence of confirmed COVID-19 cases OR mortality rate OR severity assessment OR ICU admission among patients with beta-thalassemia minor, were included in this analysis. The language was limited to English. Studies such as case reports, review studies, and studies that did not have complete data for calculating incidences were excluded. Results and discussion: Three studies upon 2265 were selected. According to our systematic-review meta-analysis, beta-thalassemia carriers could be less COVID-19 affected than general population [IRR= 0.9250(0.5752;1.4877)], affected by COVID-19 with a worst severity [OR=1.5933(0.4884;5.1981)], less admissible into ICU [IRR=0.3620(0.0025;51.6821)] and more susceptible to die from COVID-19 or one of its consequences [IRR=1.8542(0.7819;4.3970)]. However, all of those results stay insignificant with a bad p-value (respectively 0.7479, 0.4400, 0.6881, 0.1610). Other large case-control or registry studies are needed to confirm these trends.
    Keywords covid19
    Language English
    Publishing date 2022-07-25
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2022.07.25.22278009
    Database COVID19

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