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  1. Article ; Online: Polo-like kinase 1 inhibition in KRAS-mutated metastatic colorectal cancer.

    Stebbing, Justin / Bullock, Andrea J

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2024  

    Abstract: Inhibition of Polo-like kinase 1 (Plk1) is a promising new target and therapeutic strategy in metastatic colorectal cancer, especially those with KRAS mutations. New data support further development of onvansertib, and highlights the role of circulating ... ...

    Abstract Inhibition of Polo-like kinase 1 (Plk1) is a promising new target and therapeutic strategy in metastatic colorectal cancer, especially those with KRAS mutations. New data support further development of onvansertib, and highlights the role of circulating tumor DNA in phase 1 clinical trials.
    Language English
    Publishing date 2024-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-24-0251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Genes and Race in Colon Cancer.

    Stebbing, Justin / Schlechter, Benjamin L

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 42, Issue 4, Page(s) 369–372

    MeSH term(s) Humans ; Colonic Neoplasms/genetics ; Black or African American
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.02094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Baricitinib as the treatment of choice for hospitalised individuals with COVID-19.

    Richardson, Peter J / Stebbing, Justin

    EClinicalMedicine

    2022  Volume 49, Page(s) 101493

    Language English
    Publishing date 2022-06-03
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2022.101493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Developments in paediatric cancer care throughout the COVID-19 pandemic: Lessons from China.

    Boiardi, Federico / Stebbing, Justin

    The Lancet regional health. Western Pacific

    2022  Volume 20, Page(s) 100398

    Language English
    Publishing date 2022-02-18
    Publishing country England
    Document type Journal Article
    ISSN 2666-6065
    ISSN (online) 2666-6065
    DOI 10.1016/j.lanwpc.2022.100398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Baricitinib as the treatment of choice for hospitalised individuals with COVID-19

    Peter J. Richardson / Justin Stebbing

    EClinicalMedicine, Vol 49, Iss , Pp 101493- (2022)

    2022  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: JAK Inhibitors - More Than Just Glucocorticoids.

    Stebbing, Justin / Lauschke, Volker M

    The New England journal of medicine

    2021  Volume 385, Issue 5, Page(s) 463–465

    MeSH term(s) Glucocorticoids ; Humans ; Janus Kinase Inhibitors ; Signal Transduction
    Chemical Substances Glucocorticoids ; Janus Kinase Inhibitors
    Language English
    Publishing date 2021-07-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2108667
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Baricitinib: the first immunomodulatory treatment to reduce COVID-19 mortality in a placebo-controlled trial.

    Kalil, Andre C / Stebbing, Justin

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 12, Page(s) 1349–1351

    MeSH term(s) Azetidines ; COVID-19/drug therapy ; Humans ; Purines ; Pyrazoles ; SARS-CoV-2 ; Sulfonamides
    Chemical Substances Azetidines ; Purines ; Pyrazoles ; Sulfonamides ; baricitinib (ISP4442I3Y)
    Language English
    Publishing date 2021-09-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00358-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Profiling circulating tumour cells and cell free DNA together in metastatic colon cancer.

    Friend, Thomas / Stebbing, Justin

    British journal of cancer

    2021  Volume 125, Issue 7, Page(s) 907–908

    Abstract: The characterisation of CTCs (circulating tumour cells) and cfDNA (circulating free DNA) by Salvianti et al. highlight critical aspects of these approaches' relative strengths, weaknesses, and interdependencies in this study. ...

    Abstract The characterisation of CTCs (circulating tumour cells) and cfDNA (circulating free DNA) by Salvianti et al. highlight critical aspects of these approaches' relative strengths, weaknesses, and interdependencies in this study.
    MeSH term(s) Cell Count ; Cell-Free Nucleic Acids/genetics ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; GTP Phosphohydrolases/genetics ; Humans ; Liquid Biopsy ; Membrane Proteins/genetics ; Mutation ; Neoplasm Metastasis ; Neoplastic Cells, Circulating/chemistry ; Neoplastic Cells, Circulating/pathology ; Proto-Oncogene Proteins p21(ras)/genetics ; Survival Analysis
    Chemical Substances Cell-Free Nucleic Acids ; KRAS protein, human ; Membrane Proteins ; GTP Phosphohydrolases (EC 3.6.1.-) ; NRAS protein, human (EC 3.6.1.-) ; Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
    Language English
    Publishing date 2021-05-05
    Publishing country England
    Document type Editorial
    ZDB-ID 80075-2
    ISSN 1532-1827 ; 0007-0920
    ISSN (online) 1532-1827
    ISSN 0007-0920
    DOI 10.1038/s41416-021-01397-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reducing transmission of SARS-CoV-2 with intranasal prophylaxis

    Federico Boiardi / Justin Stebbing

    EBioMedicine, Vol 63, Iss , Pp 103170- (2021)

    2021  

    Keywords Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: COVID-19 and the risk to cancer patients in China.

    Williams, Jennet / Stebbing, Justin

    International journal of cancer

    2020  Volume 148, Issue 2, Page(s) 265–266

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; China/epidemiology ; Comorbidity ; Humans ; Neoplasms/epidemiology ; Neoplasms/therapy ; Pandemics ; Risk Assessment/methods ; Risk Assessment/statistics & numerical data ; Risk Factors ; SARS-CoV-2/physiology
    Keywords covid19
    Language English
    Publishing date 2020-10-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 218257-9
    ISSN 1097-0215 ; 0020-7136
    ISSN (online) 1097-0215
    ISSN 0020-7136
    DOI 10.1002/ijc.33325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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