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  1. Article ; Online: What is a low low-molecular-weight heparin dose?

    Godier, Anne / Llau, Juan V / Ferrandis, Raquel / Langenecker, Sibylle

    European journal of anaesthesiology

    2024  Volume 41, Issue 5, Page(s) 393

    MeSH term(s) Humans ; Heparin, Low-Molecular-Weight/adverse effects ; Heparin/adverse effects ; Anticoagulants/adverse effects
    Chemical Substances Heparin, Low-Molecular-Weight ; Heparin (9005-49-6) ; Anticoagulants
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000001962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: HEMOMAS-II, an update on the massive hemorrhage management.

    Colomina, María J / Ferrandis Comes, Raquel

    Medicina intensiva

    2023  Volume 47, Issue 8, Page(s) 425–426

    MeSH term(s) Humans ; Hemorrhage/etiology ; Hemorrhage/therapy ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-08-03
    Publishing country Spain
    Document type Editorial ; Comment
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2023.05.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Periprocedural use of antithrombotic therapy in interventional cardiology in Spain: are we doing better than other specialties?

    Anguita-Gámez, María / Vivas, David / Ferrandis, Raquel / Esteve-Pastor, María Asunción / Marín, Francisco / Anguita Sánchez, Manuel

    Revista espanola de cardiologia (English ed.)

    2024  

    Language Spanish
    Publishing date 2024-04-03
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2024.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Optimization of Plant Production by Seed Treatment in Two Wild Subspecies of

    Herranz, Raquel / Copete, Miguel A / Herranz, José M / Copete, Elena / Ferrandis, Pablo

    Molecules (Basel, Switzerland)

    2020  Volume 25, Issue 19

    Abstract: ... The ... ...

    Abstract The daffodil
    MeSH term(s) Alkaloids/metabolism ; Germination ; Narcissus/classification ; Narcissus/growth & development ; Plant Dormancy ; Seedlings/classification ; Seedlings/growth & development ; Seeds/growth & development
    Chemical Substances Alkaloids
    Language English
    Publishing date 2020-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules25194439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Management of perioperative thromboprophylaxis for surgery following COVID-19: an expert-panel survey.

    Ferrandis, Raquel / Llau, Juan V / Afshari, Arash / Douketis, James D / Gómez-Luque, Aurelio / Samama, Charles-Marc

    British journal of anaesthesia

    2021  Volume 127, Issue 4, Page(s) e143–e145

    MeSH term(s) Anticoagulants/therapeutic use ; COVID-19/complications ; Humans ; Perioperative Care/methods ; SARS-CoV-2 ; Time ; Venous Thromboembolism/complications ; Venous Thromboembolism/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-07-09
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.06.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Letter by Llau and Ferrandis regarding article, "Bridging evidence-based practice and practice-based evidence in periprocedural anticoagulation".

    Llau, Juan V / Ferrandis, Raquel

    Circulation

    2013  Volume 127, Issue 19, Page(s) e616

    MeSH term(s) Hemorrhage/epidemiology ; Heparin/adverse effects ; Humans ; Perioperative Care ; Thromboembolism/prevention & control ; Vitamin K/antagonists & inhibitors
    Chemical Substances Vitamin K (12001-79-5) ; Heparin (9005-49-6)
    Language English
    Publishing date 2013-05-14
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.112.151506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19: opening a new paradigm in thromboprophylaxis for critically ill patients?

    Ferrandis, Raquel / Llau, Juan V / Quintana, Manuel / Sierra, Pilar / Hidalgo, Francisco / Cassinello, Concepción / Gómez-Luque, Aurelio

    Critical care (London, England)

    2020  Volume 24, Issue 1, Page(s) 332

    MeSH term(s) Anticoagulants/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/therapy ; Critical Illness ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/therapy ; Pulmonary Embolism/complications ; Pulmonary Embolism/prevention & control ; SARS-CoV-2 ; Venous Thromboembolism/prevention & control
    Chemical Substances Anticoagulants ; Heparin, Low-Molecular-Weight
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country England
    Document type Letter
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-020-03052-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optimization of Plant Production by Seed Treatment in Two Wild Subspecies of Narcissus pseudonarcissus Rich in Alkaloids

    Raquel Herranz / Miguel A. Copete / José M. Herranz / Elena Copete / Pablo Ferrandis

    Molecules, Vol 25, Iss 4439, p

    2020  Volume 4439

    Abstract: The daffodil Narcissus pseudonarcissus L. contains alkaloids of pharmaceutical interest. Wild daffodil populations have diverse genetic backgrounds and various genetic traits of possible importance. Developing protocols for plant production from seeds ... ...

    Abstract The daffodil Narcissus pseudonarcissus L. contains alkaloids of pharmaceutical interest. Wild daffodil populations have diverse genetic backgrounds and various genetic traits of possible importance. Developing protocols for plant production from seeds may ensure the availability of a large reservoir of individuals as well as being important for species with bulbs that are difficult to acquire. The closely related Narcissus pseudonarcissus subsp. munozii-garmendiae and subsp. nevadensis were investigated in this study because the alkaloids isolated from both are of high pharmacological interest. At the dispersal time, the seeds of both were dormant with underdeveloped embryos, i.e., morphophysiological dormancy (MPD). Experiments were conducted outdoors and under controlled laboratory conditions. Embryo growth and the percentages of radicle and seedling emergence were calculated under different temperature–light stratifications. In N. munozii-garmendiae , embryo growth occurred during warm stratification (28/14 °C or 25/10 °C) and the radicle then emerged when the temperature decreased, but the shoot was dormant. In N. nevadensis , the seeds germinated when cold stratified (5 °C) and then incubated at cool temperatures. Thus, N. munozii-garmendiae and N. nevadensis exhibit different levels of MPD, i.e., deep simple epicotyl and intermediate complex, respectively. Plant production protocols from seeds were established for both taxa in this study.
    Keywords alkaloid ; Amaryllidaceae ; deep simple epicotyl morphophysiological dormancy ; dormancy breakage ; embryo growth ; germination ; Organic chemistry ; QD241-441
    Subject code 580
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: COVID-19

    Raquel Ferrandis / Juan V. Llau / Manuel Quintana / Pilar Sierra / Francisco Hidalgo / Concepción Cassinello / Aurelio Gómez-Luque

    Critical Care, Vol 24, Iss 1, Pp 1-

    opening a new paradigm in thromboprophylaxis for critically ill patients?

    2020  Volume 3

    Keywords Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Prospective observational registry of perioperative and periprocedural management of antithrombotic therapy in "real world": the REQXAA study.

    Vivas, David / Anguita-Gámez, María / Ferrandis, Raquel / Esteve-Pastor, María Asunción / Echeverri, Marysol / Igualada, Jesús / Anguita, Manuel / Egocheaga, Isabel / Nozal-Mateo, Beatriz / Abad-Motos, Ane / Figuero, Elena / Bouzó-Molina, Nuria / Lozano, Teresa / Álvarez-Ortega, Carlos / Torres, Javier / Descalzo, María José / Catalá, Juan Carlos / Martín-Rioboo, Enrique / Molines, Alejandra /
    Rodríguez-Contreras, Rocío / Carnero-Alcázar, Manuel / Marín, Francisco

    Revista espanola de cardiologia (English ed.)

    2023  Volume 76, Issue 9, Page(s) 729–738

    Abstract: Introduction and objectives: There is scarce real-world evidence on the management of perioperative antithrombotic treatment according to current recommendations. The aim of this study was to analyze the management of antithrombotic treatment in ... ...

    Abstract Introduction and objectives: There is scarce real-world evidence on the management of perioperative antithrombotic treatment according to current recommendations. The aim of this study was to analyze the management of antithrombotic treatment in patients undergoing surgery or another invasive intervention and to assess the consequences of this management on the occurrence thrombotic or bleeding events.
    Methods: This prospective, observational, multicenter and multispecialty study analyzed patients receiving antithrombotic therapy who underwent surgery or another invasive intervention. The primary endpoint was defined as the incidence of adverse (thrombotic and/or hemorrhagic) events after 30 days of follow-up with respect to management of perioperative antithrombotic drugs.
    Results: We included 1266 patients (male: 63.5%; mean age 72.6 years). Nearly half of the patients (48.6%) were under chronic anticoagulation therapy (mainly for atrial fibrillation; CHA
    Conclusions: The implementation of recommendations on the perioperative/periprocedural management of antithrombotic therapy in real-world patients is poor. Inappropriate management of antithrombotic treatment is associated with an increase in both thrombotic and hemorrhagic events.
    MeSH term(s) Humans ; Male ; Aged ; Anticoagulants/therapeutic use ; Fibrinolytic Agents/therapeutic use ; Fibrinolytic Agents/adverse effects ; Prospective Studies ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology ; Hemorrhage/complications ; Risk Factors ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Registries ; Platelet Aggregation Inhibitors/adverse effects
    Chemical Substances Anticoagulants ; Fibrinolytic Agents ; Platelet Aggregation Inhibitors
    Language Spanish
    Publishing date 2023-03-11
    Publishing country Spain
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2023.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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