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  1. Article ; Online: Unlocking tracheoesophageal speech from pharyngoesophageal spasm: preliminary results of a videofluoroscopic-guided botulinum toxin A injection technique.

    Bandi, Francesco / Chu, Francesco / Zurlo, Valeria / Di Natale, Valentina / Zorzi, Stefano / Pietrobon, Giacomo / De Berardinis, Rita / Tagliabue, Marta / Ansarin, Mohssen

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2024  Volume 281, Issue 4, Page(s) 1885–1893

    Abstract: Purpose: The tracheoesophageal puncture for the voice prosthesis (VP) placement is the recognized gold standard in post-laryngectomy voice rehabilitation. Despite the development of specific intraoperative techniques, a subset of patients will suffer ... ...

    Abstract Purpose: The tracheoesophageal puncture for the voice prosthesis (VP) placement is the recognized gold standard in post-laryngectomy voice rehabilitation. Despite the development of specific intraoperative techniques, a subset of patients will suffer from poor functional outcomes due to pharyngoesophageal spasms (PES). This paper evaluates the functional outcomes after transcutaneous botulinum toxin type A (BTX-A) infiltration for PES with a videofluoroscopy-guided technique.
    Methods: Since 2022, eight consecutive patients with VP and affected by PES were treated with BTX-A injection by a standard videofluoroscopic guided technique at the European Institute of Oncology, IRCCS (IEO) in Milan. A lidocaine test was performed pre-operatively to evaluate the potential effect of chemical neurectomy. All patients with positive lidocaine tests were injected with 50 IU of BTX-A (Allergan, Irvine, CA) according to the sites marked during the videofluoroscopy. Reported symptoms (VHI, SECEL), perceptual (INFVo), aerodynamic (MPT) and manometric parameters were collected before and after treatment.
    Results: In all cases, BTX-A was performed as an outpatient procedure without complications. For seven patients, only one BTX-A injection was needed, while one patient required a re-injection. Subjective and perceptive improvement after BTX-A was significant for VHI, SECEL and INFVo. MPT showed significant improvement after a chemical neurectomy. After a mean follow-up of 6 months, all patients maintained a good TES quality.
    Conclusion: The videofluoroscopic guided BTX-A injection of the pharyngoesophageal tract showed to be a feasible and reproducible technique in all cases. The pharyngoesophageal videofluoroscopy allows defining of patients' anatomical landmarks that help the surgeon to perform a homogeneous injection, empowered by post-injection massage.
    MeSH term(s) Humans ; Botulinum Toxins, Type A ; Speech ; Laryngectomy/adverse effects ; Speech, Esophageal ; Spasm/etiology ; Lidocaine ; Treatment Outcome
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69) ; Lidocaine (98PI200987)
    Language English
    Publishing date 2024-01-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-024-08448-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to "From compartmental to anatomically-based circumferential resection-Is the trend reversal of justified?"

    Calabrese, Luca / Pietrobon, Giacomo / Fazio, Enrico / Accorona, Remo

    Head & neck

    2020  Volume 42, Issue 9, Page(s) 2766–2767

    MeSH term(s) Carcinoma, Squamous Cell ; Head and Neck Neoplasms ; Humans ; Rectal Neoplasms ; Squamous Cell Carcinoma of Head and Neck ; Tongue Neoplasms
    Language English
    Publishing date 2020-05-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 645165-2
    ISSN 1097-0347 ; 0148-6403 ; 1043-3074
    ISSN (online) 1097-0347
    ISSN 0148-6403 ; 1043-3074
    DOI 10.1002/hed.26254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nasopharyngeal swabs during SARS-CoV-2 pandemic: a role for the otolaryngologist.

    Tagliabue, Marta / Pietrobon, Giacomo / Ugolini, Sara / Chu, Francesco / Ansarin, Mohssen

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2020  Volume 277, Issue 7, Page(s) 2155–2157

    Keywords covid19
    Language English
    Publishing date 2020-05-07
    Publishing country Germany
    Document type Letter
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-020-06027-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply to "Could a mannequin simplify rhinopharyngeal swab collection in COVID 19 patients?"

    Tagliabue, Marta / Pietrobon, Giacomo / Ugolini, Sara / Chu, Francesco / Ansarin, Mohssen

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2020  Volume 277, Issue 10, Page(s) 2949–2950

    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Humans ; Manikins ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-18
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-020-06186-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19 and head and neck cancer management. Experience of an oncological hub comprehensive cancer centre and literature review.

    Chu, Francesco / Zocchi, Jacopo / De Berardinis, Rita / Bandi, Francesco / Pietrobon, Giacomo / Scaglione, Donatella / Radice, Davide / Tagliabue, Marta / Ansarin, Mohssen

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2022  Volume 42, Issue Suppl. 1, Page(s) S79–S86

    MeSH term(s) COVID-19 ; Head and Neck Neoplasms/therapy ; Humans
    Language English
    Publishing date 2022-06-28
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-suppl.1-42-2022-09
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Practical Guide for Identification of Internal Carotid Artery During Endoscopic Nasopharyngectomy.

    Battaglia, Paolo / Eesa, Mohamed / Pietrobon, Giacomo / Karligkiotis, Apostolos / Castelnuovo, Paolo / Turri-Zanoni, Mario

    The Laryngoscope

    2020  Volume 131, Issue 3, Page(s) E755–E758

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Anatomic Landmarks/surgery ; Carotid Artery, Internal/anatomy & histology ; Endoscopy/methods ; Eustachian Tube/surgery ; Female ; Humans ; Male ; Middle Aged ; Nasal Surgical Procedures/methods ; Nasopharyngeal Neoplasms/surgery ; Nasopharynx/anatomy & histology ; Pharyngectomy/methods
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID alias challenge to onco-rehabilitation and to viable indications and decisions: Cues from an Italian COVID+ oral cancer patient.

    Pietrobon, Giacomo / Tagliabue, Marta / Chu, Francesco / De Berardinis, Rita / Ansarin, Mohssen

    Oral oncology

    2020  Volume 105, Page(s) 104745

    MeSH term(s) Betacoronavirus ; COVID-19 ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/virology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Humans ; Italy ; Male ; Middle Aged ; Mouth Neoplasms/diagnosis ; Mouth Neoplasms/virology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country England
    Document type Case Reports ; Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2020.104745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Reply to "Could a mannequin simplify rhinopharyngeal swab collection in COVID 19 patients?"

    Tagliabue, Marta / Pietrobon, Giacomo / Ugolini, Sara / Chu, Francesco / Ansarin, Mohssen

    Eur Arch Otorhinolaryngol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #637723
    Database COVID19

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  9. Article: Nasopharyngeal swabs during SARS-CoV-2 pandemic: a role for the otolaryngologist

    Tagliabue, Marta / Pietrobon, Giacomo / Ugolini, Sara / Chu, Francesco / Ansarin, Mohssen

    Eur Arch Otorhinolaryngol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #197414
    Database COVID19

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  10. Article ; Online: Outcomes of mini-invasive transoral surgery without neck dissection in supraglottic laryngeal cancer: Real world data from a tertiary cancer center.

    Zorzi, Stefano / Pietrobon, Giacomo / Mossinelli, Chiara / Bandi, Francesco / Chu, Francesco / Tagliabue, Marta / De Berardinis, Rita / Zocchi, Jacopo / Alterio, Daniela / Rocca, Maria Cossu / Ruju, Francesca / Ansarin, Mohssen

    American journal of otolaryngology

    2023  Volume 45, Issue 1, Page(s) 104113

    Abstract: Purpose: The neck management in early-stage cN0 supraglottic cancer represents an argument of debate. The aim of our study is to evaluate the oncological and functional outcomes in patients with early-stage cN0 supraglottic carcinoma treated with a wait- ...

    Abstract Purpose: The neck management in early-stage cN0 supraglottic cancer represents an argument of debate. The aim of our study is to evaluate the oncological and functional outcomes in patients with early-stage cN0 supraglottic carcinoma treated with a wait-and-see policy for the neck.
    Materials and methods: Retrospective monocentric cohort study in a referral cancer care center. We collected a consecutive sample of patients from 2000 to 2020 with Squamous Cell Carcinoma of the supraglottis without clinical evidence of nodal metastases (cN0), surgically treated with Transoral Surgery (Laser or Robotic) without neck dissection. From 316 supraglottic cancer we finally selected 66 eligible participants that met all inclusion criteria.
    Results: Sixty-six patients (M 75.8 % vs F 24.2 %), median age 65.8 years (IQR 60.9, 70.5). The most common subsite was the epiglottis (62.1 %). Tumor stage distribution was as follows: 35 % cT1, 53 % cT2, 15.2 % cT3. Neither deaths nor major treatment-related complications were reported after surgery. The median follow-up was 62 months. For oncological outcomes, we evaluated 56 patients (10 excluded for adjuvant radiotherapy): 5-year overall survival rate 87 % (CI 95 %: 73.1-94), disease- specific survival rate 95.3 % (CI 95 %: 82-98.8) and neck recurrence-free survival rate 87 % (CI 95 %: 73.1-94). Six patients developed neck recurrence, with a median time of 13 months.
    Conclusions: Supraglottic carcinoma has been historically associated to a considerable risk of occult metastasis. However, in early-stage cases data are still inconclusive. Our results suggest that in such patients a wait-and-see policy does not impact negatively on survival outcomes, while granting the reduced morbidity associated to a minimally invasive surgical approach.
    MeSH term(s) Humans ; Aged ; Laryngeal Neoplasms/pathology ; Neck Dissection/methods ; Retrospective Studies ; Cohort Studies ; Neoplasm Staging ; Carcinoma, Squamous Cell/pathology
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.104113
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