Article ; Online: Considering a Biologic: What's a Clinician to Do? Screening and Laboratory Monitoring for Biologic Therapies in the Treatment of Psoriasis.
2022 Volume 20, Issue 1, Page(s) 14–17
Abstract: Biologic therapies have revolutionized the treatment of psoriasis; however, these immunomodulatory therapies may increase the risk of reactivation of latent and chronic infections. Tumor necrosis factor alpha (TNF-α) inhibitors, in particular, have been ... ...
Abstract | Biologic therapies have revolutionized the treatment of psoriasis; however, these immunomodulatory therapies may increase the risk of reactivation of latent and chronic infections. Tumor necrosis factor alpha (TNF-α) inhibitors, in particular, have been associated with the increased risk of reactivation of tuberculosis (TB) in patients with latent TB, as well as hepatitis B virus (HBV), in patients with chronic HBV infections. Currently, baseline TB tests are the only screening tests supported with strong evidence. High-grade evidence for HBV screening tests is lacking; however, these tests are sometimes performed in clinical practice. We describe current recommendations for screening tests prior to the initiation of biologic therapy. |
---|---|
MeSH term(s) | Biological Therapy ; Hepatitis B virus/physiology ; Humans ; Immunologic Factors/therapeutic use ; Latent Tuberculosis/complications ; Latent Tuberculosis/diagnosis ; Psoriasis/complications ; Psoriasis/drug therapy ; Tumor Necrosis Factor-alpha |
Chemical Substances | Immunologic Factors ; Tumor Necrosis Factor-alpha |
Language | English |
Publishing date | 2022-02-28 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 2171125-2 |
ISSN | 1751-7125 ; 1540-9740 |
ISSN (online) | 1751-7125 |
ISSN | 1540-9740 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Zs.A 6041: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.