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  1. Article: Assessment of prerequisite programs implementation at food packaging manufacturing companies and hygiene status of food packaging in a developing country: Cross-sectional study.

    Abdessater, Marilyn / Fayyad, Fady / Matta, Joseph / Karam, Layal

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19824

    Abstract: Food packaging has a critical role in all food types and along the food chain from product preservation to transportation, distribution, storage, retailing, and end-use. However, it can become a source of contamination and transfer of microorganisms to ... ...

    Abstract Food packaging has a critical role in all food types and along the food chain from product preservation to transportation, distribution, storage, retailing, and end-use. However, it can become a source of contamination and transfer of microorganisms to the packed food when its hygienic status is not well maintained. The aim of this study was to evaluate the Prerequisite programs (PRPs) implementation in 5 food packaging companies across Mount Lebanon through on-site inspections and to assess the compliance of contact surfaces, employee hands and packaging materials to microbiological specifications. Following on-site inspection, none of the companies achieved a full total score of 100% and scores ranged from 25 to 62%. Regarding the assessment of hygienic status of contact surfaces, non-conforming results (acceptable limit ≤0.6 log colony forming units (CFU)/cm
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Corrigendum à « Troubles urinaires et génito-sexuels dans le syndrome d’apnée obstructive du sommeil : revue de la littérature » [Prog. Urol. 30 (2020), 1069–1077].

    Clerget, A / Kanbar, A / Abdessater, M

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2021  Volume 31, Issue 4, Page(s) 240

    Title translation Corrigendum to "Urinary tract symptoms and erectile dysfunction in obstructive sleep apnea: Systematic review".
    Language French
    Publishing date 2021-01-21
    Publishing country France
    Document type Published Erratum
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2020.12.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Troubles urinaires et génito-sexuels dans le syndrome d’apnée obstructive du sommeil : revue de la littérature.

    Clerget, A / Kanbar, A / Abdessater, M

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2020  Volume 30, Issue 17, Page(s) 1069–1077

    Abstract: Objective: The objective of this work was to make a review of urinary tract symptoms and erectile dysfunction involved in obstructive sleep apnea (OSA) but also to study their physiopathology and potential treatments.: Methods: We conducted a ... ...

    Title translation Urinary tract symptoms and erectile dysfunction in obstructive sleep apnea: Systematic review.
    Abstract Objective: The objective of this work was to make a review of urinary tract symptoms and erectile dysfunction involved in obstructive sleep apnea (OSA) but also to study their physiopathology and potential treatments.
    Methods: We conducted a literature review in the Pubmed database using PRISMA guidelines and the MeSH terms: sleep apnea, urinary incontinence, erectile dysfunction, sexuality. All French and English articles published up to 2020 were evaluated.
    Results: The initial evaluation identified 240 articles from which 30 were included. References lists review allowed the inclusion of 26 additional articles. Nocturia, overactive bladder (OAB) and erectile dysfunction (ED) were associated with OSA. Increased levels of natriuretic peptides are behind nocturia. Nocturia is associated with higher Apnea/Hypopnea Index (AHI) (49±11 vs 24±8 episodes/hour with P=0.0001). The severity of nocturia is proportional to the severity of OSA with a positive predictive value of 71%. Intermittent nocturnal hypoxemia causes peripheral axonal damage with subsequent urgency incontinence. There is correlation between severity of OAB and the severity of OSA especially when the latter is moderate or severe. An odds ratio of 0.45 (CI95%: 0.18-0.71) is found for ED in patients who don't have OSA, associating the latter to an increased risk of ED. Intermittent nocturnal hypoxemia, the decrease in the levels of nitric oxide, and the increase in blood pressure and levels of endothelin 1 contribute to the development of ED. An early treatment of OSA with continuous positive airway pressure (CPAP) may allow a partial but significant control of urinary symptoms and erectile dysfunction associated with OSA.
    Conclusion: OSA is associated with urinary tract symptoms (nocturia and OAB) and erectile dysfunction. The severity of associated symptoms is related to the severity of OSA. Urinary and sexual troubles are reversible after treatment of OSA by CPAP. OSA research is reasonable in case of pathologic nocturia or ED with loss of morning erections.
    MeSH term(s) Erectile Dysfunction/etiology ; Humans ; Male ; Nocturia/etiology ; Sleep Apnea, Obstructive/complications ; Urinary Bladder, Overactive/etiology
    Language French
    Publishing date 2020-08-20
    Publishing country France
    Document type Journal Article ; Systematic Review
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2020.07.244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Biochemical relapse predictive factors in patients with lymph node metastases during radical prostatectomy.

    Mandoorah, Q / Benamran, D / Pinar, U / Seisen, T / Abdessater, M / Iselin, C / Rouprêt, M

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2022  Volume 32, Issue 16, Page(s) 1462–1468

    Abstract: Introduction: There are no clear recommendations for the management of patients with lymph node invasion discovered during radical prostatectomy for prostate cancer (PCa). Adequate risk stratification could personalize post-surgical adjuvant treatment. ... ...

    Abstract Introduction: There are no clear recommendations for the management of patients with lymph node invasion discovered during radical prostatectomy for prostate cancer (PCa). Adequate risk stratification could personalize post-surgical adjuvant treatment. Our objective was to identify predictive factors for biochemical relapse (BCR) in patients with lymph node (LN) invasion at the time of radical prostatectomy(RP).
    Materials and methods: Patients who underwent RP for high-risk PCa with LN invasion in two academic centres between 2008 and 2019 were included. Patients with metastatic disease or extrapelvic LN involvement were excluded. Following data were collected retrospectively: age, preoperative prostate-specific antigen level, Gleason score, clinical and pathological stage, number of metastatic LN and LN density. Outcome was BCR during follow-up. BCR-free survival was assessed by Kaplan-Meier method and its association with relevant variables was determined with log-rank test.
    Results: Twenty-six patients were included. Median (IQR) age, PSA and follow-up were 64.5 years (55-78), 9.2ng/mL (4.4-20) and 16.1 months (6-27.5), respectively. Twenty patients (77%) had BCR after surgery, accounting for 24-month BCR-free survival of 65%. Patients with LN density > 15% had better survival rates than those with ≤ 15% (40% vs. 0%, respectively, at 24 months; P=0.06) without reaching significance. Cox proportional Hazards analysis could not evidence predictive factors of BCR free-survival.
    Conclusions: LN density seemed associated with BCR-free survival within patients with high-risk PCa and positive LN at RP. However, extraprostatic extension, number of positive LN and positive surgical margins were not independent risk factors for BCR. Larger prospective studies with centralized pathological reviews are needed.
    Level of proof: 3.
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Lymphatic Metastasis ; Retrospective Studies ; Prospective Studies ; Neoplasm Recurrence, Local/surgery ; Disease-Free Survival ; Prostatectomy/methods ; Prostate-Specific Antigen ; Prostatic Neoplasms/pathology ; Recurrence
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2022-08-06
    Publishing country France
    Document type Journal Article
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2022.07.141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hard flaccid syndrome: state of current knowledge.

    Abdessater, Maher / Kanbar, Anthony / Akakpo, William / Beley, Sebastien

    Basic and clinical andrology

    2020  Volume 30, Page(s) 7

    Abstract: Introduction: Hard-flaccid syndrome is gaining increased interest among male sexual dysfunctions in the last years. It is poorly understood and defined. Most of the information comes from online forums. This paper is a review of current knowledge on the ...

    Abstract Introduction: Hard-flaccid syndrome is gaining increased interest among male sexual dysfunctions in the last years. It is poorly understood and defined. Most of the information comes from online forums. This paper is a review of current knowledge on the clinical presentation, diagnosis, pathophysiological mechanisms and treatments of this newly recognized condition.
    Material and methods: A literature review was conducted on MEDLINE, CENTRAL, PASCAL databases and google scholar, using the terms: hard, flaccid, syndrome. The research identified 16 articles published between 2018 and February 2019. After reference lists review and duplicates removal, 7 full text references were eligible and useful for our review that follows PRISMA guidelines.
    Results: The condition is acquired, chronic and painful. It is characterized by a constantly semi-rigid penis at the flaccid state and a loss in erectile rigidity. Patients have penile sensory changes, urinary symptoms, erectile dysfunction, pelvic floor muscles contraction and psychological distress. Symptoms are worse in standing position. The majority of the cases aged between their second and third decades. A traumatic injury at the base of an erect penis is the initial event. Neurovascular structures damage and subsequent sensory, muscular and vascular changes follow. Initial symptoms trigger emotional distress and reactional sympathetic stimulation that worsen symptoms. Diagnosis is based on patient's history. Imaging and blood tests are normal. Differential diagnosis includes high-flow priapism and non-erecting erections. A multimodal treatment has been so far the most beneficial strategy, consisting of behavioral modifications to reduce stress and decrease pelvic floor muscles contraction, evaluation and treatment of the associated psychological conditions, and medical therapy for pain control and the treatment of the associated erectile dysfunction.
    Conclusion: Hard-flaccid syndrome is poorly recognized in the daily clinical experience and not well defined. A multimodal approach seems so far the most efficient strategy for treatment. Additional evidence based studies with better quality are needed to define the exact pathophysiological mechanisms and subsequently more efficient therapeutic strategies.
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2732675-5
    ISSN 2051-4190
    ISSN 2051-4190
    DOI 10.1186/s12610-020-00105-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Anatomical risk factors for spermatic cord torsion and their involvement in the choice of orchidopexy technique.

    Beaud, Nicolas / Kanbar, Anthony / Abdessater, Maher

    Morphologie : bulletin de l'Association des anatomistes

    2020  Volume 105, Issue 348, Page(s) 1–9

    Abstract: Objective: We aim by this article to present a literature review on the anatomical risk factors for spermatic cord torsion and their involvement the different techniques of orchidopexy.: Materials and methods: The literature review was conducted ... ...

    Abstract Objective: We aim by this article to present a literature review on the anatomical risk factors for spermatic cord torsion and their involvement the different techniques of orchidopexy.
    Materials and methods: The literature review was conducted following PRISMA check-list, using PubMed database and the Mesh terms: testis, torsion, anomaly, orchidopexy. Techniques of surgical management provided by the EMC (French medico-surgical encyclopedia) were also used.
    Results: Database research identified 500 articles, and 16 mores articles were added from the review of the references lists of relevant articles. At the end, 42 articles were useful for our review including 6 reviews, 5 cross-sectional studies, 14 cohorts, 10 case reports, 1 meta-analysis, 1 letter, and 5 experimental studies. High insertion of the tunica vaginalis, a long mesorchium, deficient attachment of the epididymis to the testis, and anomalies of the gubernaculum testis are the anatomical predispositions for spermatic cord torsion. After reduction of torsion, many surgical techniques for the fixation of the testis have been suggested including: conventional technique by triangulation with or without fasciotomy, window orchidopexy, scrotal pouch, and vaginal eversion with or without dartos fixation.
    Conclusion: The most common anatomical factor associated with spermatic cord torsion is the high insertion of the tunica vaginalis. Vaginal eversion with fixation to the dartos might be superior to other known techniques and seems promising to become standard.
    MeSH term(s) Cross-Sectional Studies ; Humans ; Male ; Orchiopexy ; Risk Factors ; Spermatic Cord Torsion/surgery ; Testis
    Language English
    Publishing date 2020-09-09
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1443319-9
    ISSN 1286-0115
    ISSN 1286-0115
    DOI 10.1016/j.morpho.2020.06.006
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  7. Article: The "Cut-to-the-Light" Technique Laser Endoureterotomy for Complete Ureteral Obstruction Resurfaces! A New Application of an Old Technique.

    Yarak, Naim / Zouari, Skander / Karray, Omar / Sleiman, Walid / Abdelwahab, Alaa / Bart, Stéphane / Abdessater, Maher

    Research and reports in urology

    2022  Volume 14, Page(s) 351–358

    Abstract: Objective: To describe our new endoscopic approach in treating iatrogenic ureteral stenosis using the "cut-to-The-light" technique.: Methods: Case of a 54 year-old female patient who underwent a right percutaneous nephrolithotomy to treat a staghorn ... ...

    Abstract Objective: To describe our new endoscopic approach in treating iatrogenic ureteral stenosis using the "cut-to-The-light" technique.
    Methods: Case of a 54 year-old female patient who underwent a right percutaneous nephrolithotomy to treat a staghorn calculus with two subsequent complimentary ureteroscopies complicated by a severe proximal ureteral obstruction. An antegrade flexible uretereroscope and a retrograde rigid ureteroscope were used to locate the stenosis. With the aid of a 365-µm Ho: YAG laser fiber (settings 0.4 J, 12 Hz), we managed to successfully create a small incision in the stenotic lesion, the rigid ureterscopy light was clearly seen by the antegrade flexible ureteroscope and a through-and-through guidewire was then placed, securing the ureter. Ureteral dilatation was then performed followed by a full thickness incision of the ureteral stenosis. A single 8Fr, 28 cm double J ureteral stent was finally placed after stone fragmentation.
    Results: The operating time was 200 mins. No blood loss. No fever or signs of UTI were seen shortly after the operation. The Foley catheter was successfully removed at day one post-op. The hospital stay was short of only 2 days.
    Conclusion: The "cut-to-the-light" technique is a new application in the arsenal of ureteral stricture treatment that has been scarcely described in the literature before. The use of this method seems to offer excellent outcomes thus demonstrating the importance of this minimally invasive technique as an alternative to conventional invasive methods used. We believe that studies with larger samples and longer follow up are needed in order to fully determine the benefits of this method and to assess and reveal its suitable application and its drawbacks.
    Language English
    Publishing date 2022-10-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2649530-2
    ISSN 2253-2447
    ISSN 2253-2447
    DOI 10.2147/RRU.S371856
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  8. Article: Diagnosis and Management of Polyorchidism: A Case Report and Literature Review.

    Kanbar, Anthony / Dabal, Charbel / El Khoury, Joey / Halabi, Rami / Assaf, Serge / Mina, Anthony / Breidi, Sabine / Abdessater, Maher / El Khoury, Raghid

    Case reports in urology

    2023  Volume 2023, Page(s) 1620276

    Abstract: Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical ... ...

    Abstract Polyorchidism, or supernumerary testis, is a rare congenital abnormality of the genitourinary system. In this paper, we present the case of triorchidism in a seven-year-old asymptomatic child with a suspect left scrotal mass detected on routine physical examination. Imaging studies revealed a third testicle in the left hemiscrotum, with comparable dimensions, signal intensity on MRI, and Doppler flow on ultrasound with the ipsilateral testis. We also discuss the clinical presentations, classifications, and current diagnostic and therapeutic strategies of this condition.
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627659-8
    ISSN 2090-6978 ; 2090-696X
    ISSN (online) 2090-6978
    ISSN 2090-696X
    DOI 10.1155/2023/1620276
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  9. Article ; Online: La thymoglobuline en traitement d’induction chez les transplantés rénaux à faible risque immunologique: une expérience marocaine.

    Abouzid, Zineb / Amar, Mohamed Anass / Abdessater, Maher / Alioubane, Meryem / Benjaafar, Anissa / Ouzeddoun, Naima / Benamar, Loubna / Bayahia, Rabia / Bouattar, Tarik

    The Pan African medical journal

    2022  Volume 41, Page(s) 138

    Abstract: Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low ...

    Title translation Thymoglobulin as induction treatment in kidney transplantants with low immunological risk: a Moroccan experience.
    Abstract Introduction: Thymoglobulin® is a polyclonal antibody indicated for induction treatment in kidney transplantation. The purpose of this study is to estimate the effectiveness of Thymoglobulin® as induction treatment in kidney transplant patients with low immune risk.
    Methods: we conducted a retrospective study between January 2012 and September 2017. Patients with low immunological risk, defined as the absence of previous transplantation and donor-specific antibodies (DSA), were included and received Thymoglobulin® induction therapy. Demographic and clinical characteristics, biological parameters and post-renal transplant complications were studied.
    Results: we enrolled 55 kidney transplant patients with an average follow-up period of 38 ± 16 months. The average age of patients was 39,1 ± 12,1 years with a male predominance (58.2%). No patient had DSA prior to transplant. Cumulative dose of Thymoglobulin® was 4,26 ± 0,87 mg/kg, with an average duration of 5 ± 0,82 days. Lymphocyte depletion was maximal on the first day of infusion. Three patients had delayed graft function, at least one episode of bacterial infection in 56,4% of patients, 7 cases of CMV infections (12,7%) and 2 cases of CMV disease (3,6%). Graft survival rate was calculated for all patients with an average serum creatinine of 11,7 ± 3,6 mg/l during the last visit.
    Conclusion: although it is not indicated for first line treatment in patients with low immunological risk, Thymoglobulin® can nevertheless be prescribed at a lower dose, with similar efficacy and without exposure to a higher risk of rejection.
    MeSH term(s) Antilymphocyte Serum ; Cytomegalovirus Infections/drug therapy ; Female ; Graft Rejection/prevention & control ; Graft Survival ; Humans ; Immunosuppressive Agents/therapeutic use ; Infant, Newborn ; Kidney ; Male ; Retrospective Studies
    Chemical Substances Antilymphocyte Serum ; Immunosuppressive Agents ; thymoglobulin (D7RD81HE4W)
    Language French
    Publishing date 2022-02-17
    Publishing country Uganda
    Document type Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2022.41.138.23091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Bilateral laparoscopic ureterolysis using hydrodissection in retroperitoneal fibrosis: a new application of an old technique.

    Abdessater, Maher / Elias, Sandra / Boustany, Johnny / El Khoury, Raghid

    Research and reports in urology

    2019  Volume 11, Page(s) 131–135

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2019-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2649530-2
    ISSN 2253-2447
    ISSN 2253-2447
    DOI 10.2147/RRU.S201396
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