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  1. Article: Correction to: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases.

    Vangah, Somayeh Jolany / Katalani, Camellia / Boone, Hannah A / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological procedures online

    2020  Volume 22, Issue 1, Page(s) 24

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Language English
    Publishing date 2020-11-07
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00136-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases.

    Jolany Vangah, Somayeh / Katalani, Camellia / Booneh, Hannah A / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological procedures online

    2020  Volume 22, Page(s) 22

    Abstract: Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR's ... ...

    Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR's remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Keywords covid19
    Language English
    Publishing date 2020-09-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00135-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction to

    Somayeh Jolany vangah / Camellia Katalani / Hannah A. Boone / Abbas Hajizade / Adna Sijercic / Gholamreza Ahmadian

    Biological Procedures Online, Vol 22, Iss 1, Pp 1-

    CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    2020  Volume 1

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Keywords Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    Somayeh Jolany vangah / Camellia Katalani / Hannah A. Booneh / Abbas Hajizade / Adna Sijercic / Gholamreza Ahmadian

    Biological Procedures Online, Vol 22, Iss 1, Pp 1-

    2020  Volume 14

    Abstract: Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to ... ...

    Abstract Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR’s remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Keywords CRISPR-Cas ; COVID-19 ; Diagnostic test ; SHERLOCK ; DETECTR ; Single guide RNA (sgRNA) ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    Jolany vangah, Somayeh / Katalani, Camellia / Booneh, Hannah A. / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological Procedures Online

    2020  Volume 22, Issue 1

    Abstract: Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to ... ...

    Abstract Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR’s remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Keywords General Biochemistry, Genetics and Molecular Biology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00135-3
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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