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Article: Value of the New Elastography Technique using Acoustic Radiation Force Impulse in Differentiation between Hashimoto's Thyroiditis and Graves' Disease.

Hefeda, Mohamed Mohamed

2019 Volume 9, Page(s) 17

Abstract: Background and aim: This study was performed to evaluate the role and accuracy of shear wave elastography in the differentiation between Graves' disease (GD) and Hashimoto's thyroiditis (HT), in comparison with the B-mode ultrasound and color Doppler ... ...

Abstract	Background and aim: This study was performed to evaluate the role and accuracy of shear wave elastography in the differentiation between Graves' disease (GD) and Hashimoto's thyroiditis (HT), in comparison with the B-mode ultrasound and color Doppler ultrasound. Materials and methods: This study was non-randomized prospective study. The study included 30 patients with GD, 65 patients with HT, and 35 patients with normal thyroid glands. Assessment of ultrasonographic criteria, color Doppler flow pattern, and shear patterns differed significantly between the control group and the group of diffuse thyroid disease ( Conclusion: Quantitative and qualitative SWE is useful for diagnosing diffuse thyroid disease and evaluating the degree of fibrosis in autoimmune thyroiditis. However, acoustic radiation force impulse techniques cannot differentiate between HT and GD reliably.
Language	English
Publishing date	2019-05-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2601233-9
ISSN	2156-5597 ; 2156-7514
ISSN (online)	2156-5597
ISSN	2156-7514
DOI	10.25259/JCIS-22-2019
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: CT chest findings in patients infected with COVID-19

Mohamed Mohamed Hefeda

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 51, Iss 1, Pp 1-

review of literature

2020 Volume 15

Abstract: Abstract Background Coronavirus disease 2019 (COVID-19) is a highly infectious disease causing severe respiratory distress syndrome that was first discovered by the end of 2019 in Wuhan, China. Main text A wide variety of CT findings in COVID-19 have ... ...

Abstract	Abstract Background Coronavirus disease 2019 (COVID-19) is a highly infectious disease causing severe respiratory distress syndrome that was first discovered by the end of 2019 in Wuhan, China. Main text A wide variety of CT findings in COVID-19 have been reported in different studies, and the CT findings differ according to the stage of the disease and disease severity and associated co-morbidities. We will discuss each sign separately and its importance in diagnosis and prognosis. Conclusion CT plays a pivotal role in the diagnosis and management of COVID-19 pneumonia. The typical appearance of COVID-19 pneumonia is bilateral patchy areas of ground glass infiltration, more in the lower lobes. The appearance of other signs like consolidation, air bronchogram, crazy pavement appearance, and air bubble signs appear during the course of the disease. In the context of pandemic, the CT chest can be used as a screening tool in symptomatic patients as it is cheaper, available, and time saving.
Keywords	Chest CT ; Coronavirus ; COVID-19 pneumonia ; Pneumonia ; Viral pneumonia ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Shear wave velocity by quantitative acoustic radiation force impulse in the placenta of normal and high-risk pregnancy

Mohamed Mohamed Hefeda / Alshymaa Zakaria

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 51, Iss 1, Pp 1-

2020 Volume 12

Abstract: Abstract Background Traditionally, the placental functional integrity is suggested by indirect ultrasound measurements like fetal growth, amniotic fluid index, and uterine and umbilical artery Doppler indices. Only recently the elasticity of the placenta ...

Abstract	Abstract Background Traditionally, the placental functional integrity is suggested by indirect ultrasound measurements like fetal growth, amniotic fluid index, and uterine and umbilical artery Doppler indices. Only recently the elasticity of the placenta is studied as a measure of placental consistency and biomechanical prosperities and may reflect the placental function. Shear wave velocity is the quantitative parameter of the shear wave elastography. A high-risk pregnancy is a situation which puts the mother, the fetus, or both at greater risk than a normal pregnancy. Results The shear wave velocity (SWV) showed no significant difference between the placenta of normal pregnancies in the second and third trimesters (0.85 ± 0.43 m/s and 0.89 ± 0.57 m/s, respectively). The placenta of patients with preeclampsia/eclampsia had high SWV in the second and third trimesters (2.13 ± 1.48 m/s and 2.23 ± 1.48 m/s) with a highly significant difference from the normal placenta (P < 0.001). The placentas with abnormal location (placenta previa) and penetration (placenta accreta) had higher SWV than the placenta of normal pregnancies. The mean SWV for placenta previa was 1.1 ± 0.74 m/s and 1.3 ± 0.81 m/s in the second and third trimesters, respectively, with a mildly significant difference with the normal placenta. The placenta accreta shows high mean SWV in the second and third trimesters (1.6 ± 0.65 m/s and 1.961.6 ± 0.65, respectively) which differed significantly (P < 0.001) from SWV in the normal placenta in the second and third trimesters. Conclusion Shear wave velocity measurement as the quantitative parameter of acoustic radiation force impulse (ARFI) elastography reflects the placental elasticity in normal and high-risk pregnancies. The SWV increases in conditions like hypertension, preeclampsia, maternal renal disease, and diabetes and reflects the structural and biomechanical abnormalities in such diseases. High shear wave velocity correlates with the incidence of growth restriction and abnormal Doppler ...
Keywords	Shear wave elastography ; Shear wave velocity ; Placenta ; Acoustic radiation force impulse ; Placental insufficiency ; Placenta accreta ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
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Article ; Online: Correlation between the initial CT chest findings and short-term prognosis in Egyptian patients with COVID-19 pneumonia

Mohamed Mohamed Hefeda / Dalia Ezzat Elsharawy / Tamer Mahmoud Dawoud

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 53, Iss 1, Pp 1-

2022 Volume 17

Abstract: Abstract Background The recent pandemic of COVID‐19 has thrown the world into chaos due to its high rate of transmissions. This study aimed to highlight the encountered CT findings in 910 patients with COVID-19 pneumonia in Egypt including the mean ... ...

Abstract	Abstract Background The recent pandemic of COVID‐19 has thrown the world into chaos due to its high rate of transmissions. This study aimed to highlight the encountered CT findings in 910 patients with COVID-19 pneumonia in Egypt including the mean severity score and also correlation between the initial CT finding and the short-term prognosis in 320 patients. Results All patients had confirmed COVID-19 infection. Non-contrast CT chest was performed for all cases; in addition, the correlation between each CT finding and disease severity or the short-term prognosis was reported. The mean age was higher for patients with unfavorable prognosis (P < 0.01). The patchy pattern was the most common, found in 532/910 patients (58.4%), the nodular pattern was the least common 123/910 (13.5%). The diffuse pattern was reported in 124 (13.6%). The ground glass density was the most common reported density in the study 512/910 (56.2%). The crazy pavement sign was reported more frequently in patients required hospitalization or ICU and was reported in 53 (56.9%) of patients required hospitalization and in 29 (40.2%) patients needed ICU, and it was reported in 11 (39.2%) deceased patients. Air bronchogram was reported more frequently in patients with poor prognosis than patients with good prognosis (16/100; 26% Vs 12/220; 5.4%). The mean CT severity score for patients with poor prognosis was 15.2. The mean CT severity score for patients with good prognosis 8.7., with statistically significant difference (P = 0.001). Conclusion Our results confirm the important role of the initial CT findings in the prediction of clinical outcome and short-term prognosis. Some signs like subpleural lines, halo sign, reversed halo sign and nodular shape of the lesions predict mild disease and favorable prognosis. The crazy paving sign, dense vessel sign, consolidation, diffuse shape and high severity score predict more severe disease and probably warrant early hospitalization. The high severity score is most important in prediction of ...
Keywords	COVOD-19 ; COVID-19 chest CT ; COVID-19 pneumonia ; COVID-19 prognosis ; COVID-19 CT severity score ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prediction of short term outcome of pulmonary embolism

Mohamed Mohamed Hefeda / Magdy Mohamed Elmasry

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 45, Iss 4, Pp 1089-

Parameters at 16 multi-detector CT pulmonary angiography

2014 Volume 1098

Abstract: Purpose: To evaluate the accuracy of computed tomography pulmonary angiography (CTPA) parameters, for predicting short-term mortality in patients with acute pulmonary embolism (PE). Materials and methods: Thirty-two patients with proven PE had CT ... ...

Abstract	Purpose: To evaluate the accuracy of computed tomography pulmonary angiography (CTPA) parameters, for predicting short-term mortality in patients with acute pulmonary embolism (PE). Materials and methods: Thirty-two patients with proven PE had CT pulmonary angiography were included in the study. The clot burden using the Qanadli score (QS), and the right ventricular dysfunction (RVD) parameters were assessed on CT by calculating right ventricular/left ventricular (RV/LV) diameter ratios, interventricular septum abnormality, inferior vena cava contrast reflux, azygous vein and superior vena cava measures. Contrast density in pulmonary artery and descending aorta was evaluated for all patients. Patients were followed up for 30 days and then classified as survivors or non survivors. Results: Thirty-two patients were included in the study, 23 (71.8%) of them were classified as survivors, and the other nine (28.1%) patients died within the first month (non survivors). There was a positive, but weak correlation between the Qanadli score and the short term mortality (P value = 0.05). There was a statistically significant relationship between the RV/LV ratio and PE-related mortality, with a P value < 0.001. Also, there was a good correlation between degree of IVC reflux and PE outcome (P < 0.001). The PA/AO diameter ratio, SVC diameter and azygous vein diameter showed no statistically significant difference between survivors and non survivors. Conclusions: CTPA findings that may predict short term mortality are the high grades of inferior vena cava reflux, RV/LV diameter ratio more than 1.2, and clot burden >18 according to the Qanadli score and to a lesser degree the interventricular septum abnormality.
Keywords	Pulmonary embolism ; CT pulmonary angiography ; IVC reflux ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2014-12-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Potential predictors for successful misoprostol treatment for early pregnancy failure

Dina Gamal Eldeen ELkholi / Mohamed Mohamed Hefeda

Middle East Fertility Society Journal, Vol 20, Iss 3, Pp 144-

Clinical and color Doppler imaging study

2015 Volume 153

Abstract: Objective: To identify the clinical characteristics and features of color Doppler imaging related to successful misoprostol treatment for early pregnancy failure. Design: Prospective observational study. Main outcome measures: Factors related to ... ...

Abstract	Objective: To identify the clinical characteristics and features of color Doppler imaging related to successful misoprostol treatment for early pregnancy failure. Design: Prospective observational study. Main outcome measures: Factors related to successful misoprostol treatment for early pregnancy failure. Materials and methods: Four groups of women with early pregnancy failure (missed, anembryonic and incomplete miscarriage) were included in the study. The first group included 159 cases, 73 were presenting with active vaginal bleeding and/or localized abdominal colic in the 24 h preceding misoprostol administration and 86 cases were not presenting with these symptoms. The parity of all participants was ⩾2. The second group included 143 cases that did not present with vaginal bleeding and/or abdominal colic. The parity was 0–1 in 66 cases and ⩾2 in 77 cases. The third group included 34 cases of missed miscarriage and 22 cases of anembryonic pregnancy presenting with active vaginal bleeding and/or localized abdominal colic and the parity was 0–1.The fourth group included 172 women, blood flow was detected by color Doppler imaging in the trophoblastic tissue in 90 cases and was absent in 82 cases. All participants in this group did not present with vaginal bleeding and/or localized abdominal colic and their parity was ⩾2. All participants in the four groups were given 800 μg vaginal misoprostol on day 1 of treatment. If the miscarriage was not complete on day 3 the same dose was repeated. On day 8 they were submitted to dilatation and evacuation if miscarriage was not complete. Miscarriage was considered complete when no gestation sac was detected in the uterine cavity on transvaginal ultrasonography. Results: First group: the success rate of the two doses of misoprostol, when active vaginal bleeding and/or localized abdominal colic were present, was 94.52% (69 out of 73 cases). In absence of these symptoms the success rate was 75.58% (65 out of 86 cases). The difference was statistically (p = 0.0241) significant. ...
Keywords	Early pregnancy failure ; Misoprostol ; Predictors for successful medical treatment for early miscarriage ; Medicine (General) ; R5-920 ; Reproduction ; QH471-489
Subject code	610
Language	English
Publishing date	2015-09-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preoperative sonographic and Doppler parameters predictors of semen analysis improvement after unilateral varicocelectomy

Mahmoud Abd El-Azez Dawoud / Khaled Abd El-Wahab Abo-Dewan / Mohamed Mohamed Hefeda

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 45, Iss 2, Pp 583-

2014 Volume 589

Abstract: Objective: To assess the sonographic and Doppler parameters predicting varicocelectomy outcome. Methods: This study included 86 infertile patients with abnormal semen analysis. All patients had preoperative ultrasound and color Doppler to calculate ... ...

Abstract	Objective: To assess the sonographic and Doppler parameters predicting varicocelectomy outcome. Methods: This study included 86 infertile patients with abnormal semen analysis. All patients had preoperative ultrasound and color Doppler to calculate testicular volume, pampiniform vein caliber and duration of reflux in the dilated veins during sustained valsalva maneuver. The patients underwent unilateral varicocelectomy and had semen analysis 6 months after operation, improvement index of the semen analysis was calculated. Results: The patients were classified into 2 groups: Group 1: 58 patients with normal-sized testes, and group 2 included 28 patients with subnormal testes (8–12 cm3), in the first group, the patients with improvement index >0.5 were 26 (44.8%), the group with subnormal testicular volume showed improvement in 5 patients (17.8%), the difference between the two groups was statistically significant <0.05. There was a significant positive correlation between the degree of reflux preoperatively and the improvement index (P < 0.001), also there was a positive correlation between the vein diameter and the improvement index (P = 0.03). Conclusions: The best preoperative sonographic parameters of success of unilateral varicocele repair are the presence of normal-sized testes, high grade reflux, and to lesser degree large vein diameter.
Keywords	Color doppler ; Varicocele ; Varicocelectomy ; Infertility ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	616
Language	English
Publishing date	2014-06-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Apparent diffusion coefficient of renal parenchyma and color Doppler ultrasound of intrarenal arteries in patients with cirrhosis related renal dysfunction

Mohamed M Hefeda / Khaled A Abo Dewan / Mahmoud A Dawoud

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 45, Iss 4, Pp 1275-

2014 Volume 1283

Abstract: Objectives: The aim of this work was to study the renal hemodynamic changes which occur with liver cirrhosis using diffusion weighted magnetic resonance imaging (DW-MRI) and renal color duplex Doppler ultrasound. Patients and methods: Patients were ... ...

Abstract	Objectives: The aim of this work was to study the renal hemodynamic changes which occur with liver cirrhosis using diffusion weighted magnetic resonance imaging (DW-MRI) and renal color duplex Doppler ultrasound. Patients and methods: Patients were divided into four groups: Group A: 15 cirrhotic patients with compensated liver cirrhosis, Group B: 15 cirrhotic patients with refractory ascites, Group C: 15 cirrhotic patients with hepatorenal syndrome, Group D: 10 healthy persons as a control. The apparent diffusion coefficient (ADCs) of the kidneys was calculated using low b values (ADClow) and high b values (ADChigh). Color Doppler ultrasound was performed in interlobar and arcuate arteries to calculate resistive index (RI) and pulsatility index (PI) in all patients. Results: ADClow showed a statistically significant difference between patients with hepatorenal syndrome and other groups. Using ADChigh no significant difference between different groups was noted. RI and PI of both interlobar and arcuate arteries were significantly higher in all the patient groups than the control group (P < 0.0001). RI and PI of both interlobar and arcuate arteries were significantly higher in patients with hepatorenal syndrome. Conclusion: Liver cirrhosis, even in the presence of refractory ascites, did not affect the ADC value of renal parenchyma, however ADC value is affected in renal parenchyma of patients with hepato-renal syndrome. Duplex-Doppler ultrasound of intrarenal arteries enables the early detection of renal hemodynamic disturbances in patients with liver cirrhosis.
Keywords	Diffusion weighted imaging ; Hepatorenal syndrome ; Color Doppler ultrasound ; Liver cirrhosis ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610 ; 616
Language	English
Publishing date	2014-12-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Septate or bicornuate uterus

Khaled Abd AlWahab Abo Dewan / Mohamed Mohamed Hefeda / Dina Gamal ElDein ElKholy

The Egyptian Journal of Radiology and Nuclear Medicine, Vol 45, Iss 3, Pp 987-

Accuracy of three-dimensional trans-vaginal ultrasonography and pelvic magnetic resonance imaging

2014 Volume 995

Abstract: Objective: To estimate the accuracy of 3-dimensional transvaginal ultrasonography (3D-TVUS), hysterosalpingography (HSG) and pelvic magnetic resonance imaging (MRI) in the differentiation between septate and bicornuate uterus. Patients and methods: ... ...

Abstract	Objective: To estimate the accuracy of 3-dimensional transvaginal ultrasonography (3D-TVUS), hysterosalpingography (HSG) and pelvic magnetic resonance imaging (MRI) in the differentiation between septate and bicornuate uterus. Patients and methods: Thirty-six patients with suspected septate or bicornuate uterus on 2D ultrasound or hysterosalpingography (HSG) underwent 3D-TVUS examination, MR imaging, diagnostic laparoscopy and hysteroscopy. HSG was performed only for those patients who did not undergo the procedure before (21 patients), we retrospectively revised the hysterosalpingography of 15 patients performed outside our hospital with acceptable quality. Results: HSG showed sensitivity of 77.4%, specificity of 60% and overall accuracy of 75% in the differentiation between the septate and bicornuate uterus. MRI showed sensitivity of 93.5%, specificity of 80%, PPV of 96.6% and negative predicative value of 66.6%, with overall accuracy of 91.6%. The 3D ultrasound showed the highest diagnostic parameters, with sensitivity of 96.7%, specificity of 100%, PPV of 100% and negative predicative value of 83.3%, with overall accuracy of 97.2%. Conclusions: Transvaginal 3-D ultrasonography is accurate for diagnosis and differentiation between septate uterus and bicornuate uterus. We recommend 3-D transvaginal ultrasonography as the first and only mandatory step in the assessment of the uterine cavity in patients with a suspected septate or bicornuate uterus, especially before planning surgery. MRI should be preserved for patients in whom 3D TVS is not possible like virgins.
Keywords	Mullerian duct anomalies ; Septate uterus ; Bicornuate uterus ; Three dimensional ultrasound ; Pelvic magnetic resonance imaging ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2014-09-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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