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Article ; Online: The Enhancement of Hepatic Parenchyma and Portal Vein in different CLD Groups: A Comparative Study of Gadoxetic Acid and Gadopentetate Dimeglumine.

Du, Yan-Ni / Liu, Yan-Li / Guan, Chun-Shuang / Lv, Zhi-Bin / Xing, Yu-Xue / Xue, Ming / Xie, Ru-Ming

Current medical imaging

2023

Abstract: Background: Chronic liver disease (CLD) will affect the enhancement of hepatic parenchyma and portal vein on abdominal-enhanced MRI.: Objective: To investigate the difference in liver parenchyma and portal vein enhancement in patients with CLD of ... ...

Abstract	Background: Chronic liver disease (CLD) will affect the enhancement of hepatic parenchyma and portal vein on abdominal-enhanced MRI. Objective: To investigate the difference in liver parenchyma and portal vein enhancement in patients with CLD of different liver function grades between Gd- EOB-DTPA and Gd-DPTA in the portal venous phase (PVP). Methods: This retrospective study included 218 patients with CLD who had undergone abdominal enhanced MRI from January 2019 to June 2020. Patients with various degrees of liver dysfunction were identified with Child-Turcotte-Pugh and albumin-bilirubin grade. Two readers measured the precontrast and PVP signal intensities of liver parenchyma, portal vein, spleen, and psoas muscle. Relative liver enhancement, liver-to-spleen contrast index, portal vein image contrast, and portal vein-to-liver contrast were calculated. Results: The relative enhancement of liver parenchyma was significantly lower for the Gd-EOB-DTPA group in any degree of liver function than the Gd- DTPA group in the PVP. The Gd-EOB-DTPA group showed significantly lower portal vein-to-liver contrast in the overall study population, CTP class B, and ALBI grade 2 patients compared to the group of Gd-DTPA at PVP. No significant difference was noted in the portal vein image contrast between the two contrast agents, regardless of CTP and ALBI grading. Conclusion: In CLD patients, Gd-EOB-DTPA yielded lower liver parenchymal enhancement and similar portal vein image contrast compared to Gd-DTPA in the PVP. Portal vein-to-liver contrast in the Gd-EOB-DTPA group was lower in the CTP class B and ALBI grade 2 subgroups compared to the Gd- DTPA group.
Language	English
Publishing date	2023-12-05
Publishing country	United Arab Emirates
Document type	Journal Article
ISSN	1573-4056
ISSN (online)	1573-4056
DOI	10.2174/0115734056277782231108190618
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Article: Hepatic Involvement in Acquired Immunodeficiency Syndrome-Associated Kaposi's Sarcoma: A Descriptive Analysis on CT, MRI, and Ultrasound.

Guan, Chun-Shuang / Yu, Jing / Du, Yan-Ni / Zhou, Xin-Gang / Zhang, Zi-Xin / Chen, Hui / Xing, Yu-Xue / Xie, Ru-Ming / Lv, Zhi-Bin

Infection and drug resistance

2024 Volume 17, Page(s) 1073–1084

Abstract: Purpose: To retrospectively analyse the different imaging manifestations of acquired immunodeficiency syndrome-associated hepatic Kaposi's sarcoma (AIDS-HKS) on CT, MRI, and Ultrasound.: Patients and methods: Eight patients were enrolled in the study. ...

Abstract	Purpose: To retrospectively analyse the different imaging manifestations of acquired immunodeficiency syndrome-associated hepatic Kaposi's sarcoma (AIDS-HKS) on CT, MRI, and Ultrasound. Patients and methods: Eight patients were enrolled in the study. Laboratory tests of liver function were performed. The CT, MRI, and Ultrasound manifestations were reviewed by two radiologists and two sonographers, respectively. The distribution and imaging signs of AIDS-HKS were evaluated. Results: AIDS-HKS patients commonly presented multiple lesions, mainly distributed around the portal vein on CT, MRI, and Ultrasound. AIDS-HKS presented as ring enhancement in the arterial phase on contrast-enhanced CT and MRI scanning, and nodules gradually strengthen in the portal venous phase and the delayed phase. AIDS-HKS presented as intrahepatic bile duct dilatation and bile duct wall thickening around the lesion. Five patients (62.5%, 5/8) were followed up. After chemotherapy, the lesions were completely relieved (60.0%), or decreased (40.0%). Conclusion: AIDS-HKS presented as multiple nodular lesions with different imaging features. The combination of different imaging methods was helpful for the imaging diagnosis of AIDS-HKS.
Language	English
Publishing date	2024-03-18
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2494856-1
ISSN	1178-6973
ISSN	1178-6973
DOI	10.2147/IDR.S440305
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Article ; Online: Establishment and evaluation of a CT-based radiomic model for AIDS-associated pulmonary cryptococcosis.

Zhang, Zi-Xin / Mu, Xing-Yu / Yu, Jing / Guan, Chun-Shuang / Chen, Bu-Dong / Xie, Ru-Ming

BMC medical imaging

2022 Volume 22, Issue 1, Page(s) 185

Abstract: Background: Establish a CT-based diagnostic radiomic model for AIDS complicated with pulmonary cryptococcosis and evaluate the diagnostic efficacy of this model.: Methods: This retrospective study enrolled 98 AIDS patients with pulmonary ... ...

Abstract	Background: Establish a CT-based diagnostic radiomic model for AIDS complicated with pulmonary cryptococcosis and evaluate the diagnostic efficacy of this model. Methods: This retrospective study enrolled 98 AIDS patients with pulmonary cryptococcosis and 103 AIDS patients with other infections or neoplastic lesions, comprising a total of 699 lesions. Patients were randomly divided into a training group and test group at a ratio of 2.75:1. Features from all lesions, cavity lesions and solid nodule lesions were extracted, and two kinds of radiomic models (6 types) were established. ROC curves were drawn, and the sensitivity and specificity were calculated to compare the SVM model and LR model, radiologists' empirical diagnoses and the combination of these empirical diagnoses with the radiomic model. Results: The AUCs of senior radiologist for all lesions and cavity lesions were lower than those of the SVM and LR models. The diagnostic efficacy of primary radiologist was lower than that of both of the other model types. The diagnostic efficacy of the LR model was relatively stable, with the highest diagnostic efficiency of the 3 model/radiologist groups. The AUCs of intermediate radiologist in combination with the LR radiomic model for all lesions, nodular lesions and cavity lesions were 0.88, 0.84, and 0.9, respectively, which were the highest among all models and radiologists. Conclusions: The CT-based radiomic LR model of AIDS-associated pulmonary cryptococcosis exhibits good diagnostic performance, which was similar to that of senior radiologists and higher than that of the primary radiologist. With the help of a radiomic model, radiologists can achieve improved diagnostic accuracy compared to that when only an empirical diagnosis is used.
MeSH term(s)	Humans ; Retrospective Studies ; Acquired Immunodeficiency Syndrome/complications ; Acquired Immunodeficiency Syndrome/diagnostic imaging ; ROC Curve ; Tomography, X-Ray Computed ; Cryptococcosis/diagnostic imaging
Language	English
Publishing date	2022-10-29
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2061975-3
ISSN	1471-2342 ; 1471-2342
ISSN (online)	1471-2342
ISSN	1471-2342
DOI	10.1186/s12880-022-00910-6
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Article: Long-Term Follow-Up Study of COVID-19: Evaluation on Thin-Slice CT.

Guan, Chun-Shuang / Liu, Zhi-Juan / Du, Yan-Ni / Chen, Hui / Bai, Yan / Lv, Zhi-Bin / Xu, Yan-Li / Xie, Ru-Ming / Chen, Bu-Dong

Infection and drug resistance

2022 Volume 15, Page(s) 6029–6037

Abstract: Purpose: To retrospectively analyse the CT imaging during the long-term follow-up of COVID-19 patients after discharge.: Patients and methods: A total of 122 patients entered the study group. All patients underwent CT examinations. The CT images, ... ...

Abstract	Purpose: To retrospectively analyse the CT imaging during the long-term follow-up of COVID-19 patients after discharge. Patients and methods: A total of 122 patients entered the study group. All patients underwent CT examinations. The CT images, which included distribution and imaging signs, were evaluated by two chest radiologists. Laboratory examinations included routine blood work, biochemical testing, and SARS-CoV-2 antibody screening. Statistical methods include chi-square, Fisher's exact test, one-way analysis of variance, rank sum test and logistic regression by SPSS 17.0. Results: There were 22 (18.0%) patients in the mild group, 74 (60.7%) patients in the moderate group, and 26 (21.3%) patients in the severe-critical group. The median follow-up interval was 405 days (378.0 days, 462.8 days). Only monocytes, prothrombin activity, and γ-glutamyltransferase showed significant differences among the three groups. We found that the more severe the patient's condition, the more SARS-CoV-2 IgG antibodies existed. Only 11 patients (11.0%) showed residual lesions on CT. The CT manifestations included irregular linear opacities in nine cases (9.0%), reticular patterns in six cases (6.0%), and GGOs in five cases (5.0%). Conclusion: The proportion of residual lesions on CT in COVID-19 patients was significantly reduced after long-term follow-up. The patients' age and disease conditions were positively correlated with residual lesions.
Language	English
Publishing date	2022-10-18
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2494856-1
ISSN	1178-6973
ISSN	1178-6973
DOI	10.2147/IDR.S379158
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Article ; Online: Linear shadows that connect oblique fissures and costal pleurae on the superior segments of lower lobes: evaluating the imaging findings on thin-slice lung CT.

Guan, Chun-Shuang / Lv, Zhi-Bin / Xie, Ru-Ming / Liang, Chun-Jie / Ma, Da-Qing

Japanese journal of radiology

2018 Volume 36, Issue 10, Page(s) 603–610

Abstract: Objective: To retrospectively analyse the imaging findings of the linear shadows that connect the oblique fissures and the costal pleurae on the superior segments of the lower lobes on thin-slice lung CT.: Materials and methods: Thin-slice CT scans ... ...

Abstract	Objective: To retrospectively analyse the imaging findings of the linear shadows that connect the oblique fissures and the costal pleurae on the superior segments of the lower lobes on thin-slice lung CT. Materials and methods: Thin-slice CT scans of 221 cases of normal lungs and 86 abnormal lungs were collected. The parameters of the imaging observations included the existence of the superior segmental linear shadow, its morphology, length, and starting position, bird-beak sign, and adjacent structures on the pleural end. Results: The linear shadows were more common on the left lower lobe (43.44%) than on the right side (19.46%). The pleural origins of the linear shadows were mainly located above the carina (69.78%); the adjacent structure on the left lung was the descending aorta (70.83%), and for the right lung, it was next to the thoracic vertebrae (60.47%). In the presence of pulmonary lobectomy or atelectasis, the linear shadows could be extended, which could pull the oblique fissures and costal pleurae to form the bird-beak sign. Conclusion: The linear shadows on the superior segments of the lower lobes are common structures fixing the oblique fissures. Recognition of the linear shadows can help radiologists distinguish normal structures from abnormal ones.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lung/anatomy & histology ; Lung/diagnostic imaging ; Lung Diseases/diagnostic imaging ; Male ; Middle Aged ; Pleura/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed/methods ; Young Adult
Language	English
Publishing date	2018-07-25
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2488907-6
ISSN	1867-108X ; 1867-1071
ISSN (online)	1867-108X
ISSN	1867-1071
DOI	10.1007/s11604-018-0762-z
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Article ; Online: CT imaging and pathological basis of linear shadow connecting pulmonary segmental artery to horizontal fissure.

Guan, Chun-Shuang / Yan, Shuo / Lv, Zhi-Bin / Sun, Lei / Ma, Da-Qing / Zhang, Yan-Song / Xie, Ru-Ming / Chen, Bu-Dong

Medicine

2020 Volume 99, Issue 29, Page(s) e21239

Abstract: To investigate the computed tomography (CT) imaging and pathological basis of the linear shadows connecting pulmonary segmental arteries to horizontal fissure (hereinafter referred to as "linear shadow") on thin-slice CT.Collect 127 clinical cases to ... ...

Abstract	To investigate the computed tomography (CT) imaging and pathological basis of the linear shadows connecting pulmonary segmental arteries to horizontal fissure (hereinafter referred to as "linear shadow") on thin-slice CT.Collect 127 clinical cases to analyze the display and morphology of linear shadows on the thin-slice CT and to measure their length, thickness, and angle. Collect 11 autopsy specimens of coal worker's pneumoconiosis to conduct an imaging and pathology basis control study for the linear shadows.There is no correlation between the linear shadow and gender, age, and smoking history. Linear shadows are observed in 54.33% of patients. 93.33% of those linear shadows are straight lines. Generally, the lengths are less than 10 mm, the thicknesses are around 1 mm, and the scopes of angles are wide, range from acute angles to obtuse angles. The linear shadow is a banded structure consisting of loose connective tissue, small blood vessels, and small lymphatic vessels due to the visceral pleura recessed and fused into the lung.Linear shadows are intrinsic to the lung. The linear shadows consist of loose connective tissue, small blood vessels, and small lymphatic vessels.
MeSH term(s)	Adult ; Anthracosis ; Autopsy ; Female ; Humans ; Lung Diseases/diagnostic imaging ; Lung Diseases/pathology ; Male ; Pleura/diagnostic imaging ; Pleura/pathology ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/pathology ; Tomography, X-Ray Computed
Language	English
Publishing date	2020-04-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000021239
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Article ; Online: CT findings of COVID-19 in follow-up: comparison between progression and recovery.

Guan, Chun-Shuang / Wei, Lian-Gui / Xie, Ru-Ming / Lv, Zhi-Bin / Yan, Shuo / Zhang, Zi-Xin / Chen, Bu-Dong

Diagnostic and interventional radiology (Ankara, Turkey)

2020 Volume 26, Issue 4, Page(s) 301–307

Abstract: Purpose: We aimed to retrospectively analyze the imaging changes detected in the follow-up of coronavirus disease 2019 (COVID-19) patients on thin-section computed tomography (CT).: Methods: We included 54 patients diagnosed with COVID-19. The mean ... ...

Abstract	Purpose: We aimed to retrospectively analyze the imaging changes detected in the follow-up of coronavirus disease 2019 (COVID-19) patients on thin-section computed tomography (CT). Methods: We included 54 patients diagnosed with COVID-19. The mean interval between the initial and follow-up CT scans was 7.82±3.74 days. Patients were divided into progression and recovery groups according to their outcomes. We evaluated CT images in terms of distribution of lesions and imaging manifestations. The manifestations included ground-glass opacity (GGO), crazy-paving pattern, consolidation, irregular line, and air bronchogram sign. Results: COVID-19 lesions showed mainly subpleural distribution, which was accompanied by bronchovascular bundle distribution in nearly 30% of the patients. The lower lobes of both lungs were the most commonly involved. In the follow-up, the progression group showed more involvement of the upper lobe of the left lung than the recovery group. GGO was the most common sign. As the disease progressed, round GGO decreased and patchy GGO increased. On follow-up CT, consolidation increased in the progression group while decreasing in the recovery group. Air bronchogram sign was more commonly observed at the initial examination (90.9%) than at follow-up (30%) in the recovery group, but there was no significant change in the progression group. Pleural effusion and lymphadenopathy were absent in the initial examination, but pleural effusion was observed in three cases after follow-up. Conclusion: As COVID-19 progressed, round GGOs tended to evolve into patchy GGOs, consolidation increased, and pleural effusion could be occasionally observed. As COVID-19 resolved, the crazy-paving pattern and air bronchogram significantly decreased.
MeSH term(s)	Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Diagnostic Imaging/statistics & numerical data ; Diagnostic Imaging/trends ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Male ; Middle Aged ; Pandemics ; Pleural Effusion/diagnostic imaging ; Pleural Effusion/epidemiology ; Pleural Effusion/pathology ; Pneumonia/diagnostic imaging ; Pneumonia/pathology ; Pneumonia/virology ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Retrospective Studies ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods ; Tomography, X-Ray Computed/statistics & numerical data
Keywords	covid19
Language	English
Publishing date	2020-05-21
Publishing country	Turkey
Document type	Comparative Study ; Journal Article
ZDB-ID	2184145-7
ISSN	1305-3612 ; 1305-3825
ISSN (online)	1305-3612
ISSN	1305-3825
DOI	10.5152/dir.2019.20176
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Article ; Online: MRI findings of AIDS-related giant facial Kaposi's sarcoma: A case report.

Guan, Chun-Shuang / Wang, Xue-Mei / Lv, Zhi-Bin / Yan, Shuo / Sun, Lei / Xie, Ru-Ming

Medicine

2018 Volume 97, Issue 41, Page(s) e12530

Abstract: Rationale: Kaposi's sarcoma (KS) is the most common malignant tumor in HIV-infected people and occurs mainly in the skin, mucous membranes, and lymph nodes. Approximately 33% of the initial skin manifestations of AIDS and approximately 35% to 79% of KS ... ...

Abstract	Rationale: Kaposi's sarcoma (KS) is the most common malignant tumor in HIV-infected people and occurs mainly in the skin, mucous membranes, and lymph nodes. Approximately 33% of the initial skin manifestations of AIDS and approximately 35% to 79% of KS occur during disease progression. Otherwise, AIDS-related facial KS that was simultaneously examined by magnetic resonance imaging (MRI) is rare. Patient concerns: This case was a 30-year-old male homosexual, with left facial nodule for 14 months, and HIV infection was diagnosed 1 month previously. The patient was admitted to hospital because the nodule gradually expanded from 0.2 to 10.0 cm in diameter. Ultrasound examination showed edema of the subcutaneous tissue of the left facial mass, and the boundary was not clear between lesion and normal tissues. Magnetic resonance imaging (MRI) indicated that the left facial mass showed low signal intensity on T1-weighted imaging (T1WI) and T2-weighted imaging (T2WI), and a small amount of high signal intensity was seen in it. Diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI) showed low signal intensity. After enhanced scan, the tumor showed uneven enhancement. Diagnoses: The pathological biopsy indicated KS. Interventions: The patient began chemotherapy with the intravenous drip infusion of Doxorubicin Hydrochloride Liposome. Outcomes: The facial KS decreased and the facial swelling was relieved. Lessons: MRI could not only provide the diagnostic basis of KS for the therapy, but also could accurately determine the scope of the disease.
MeSH term(s)	AIDS-Related Opportunistic Infections/diagnostic imaging ; AIDS-Related Opportunistic Infections/pathology ; Adult ; Facial Neoplasms/diagnostic imaging ; Facial Neoplasms/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Sarcoma, Kaposi/diagnostic imaging ; Sarcoma, Kaposi/pathology
Language	English
Publishing date	2018-09-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000012530
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Article ; Online: CT appearances, patterns of progression, and follow-up of COVID-19

Chun-Shuang Guan / Zhi-Bin Lv / Jing-Jing Li / Yan-Ni Du / Hui Chen / Tao Cui / Ning Guo / Bu-Dong Chen / Ru-Ming Xie

Insights into Imaging, Vol 12, Iss 1, Pp 1-

evaluation on thin-section CT

2021 Volume 12

Abstract: Abstract Background To retrospectively analyze CT appearances and progression pattern of COVID-19 during hospitalization, and analyze imaging findings of follow-up on thin-section CT. Methods CT findings of 69 patients with COVID-19 were evaluated on ... ...

Abstract	Abstract Background To retrospectively analyze CT appearances and progression pattern of COVID-19 during hospitalization, and analyze imaging findings of follow-up on thin-section CT. Methods CT findings of 69 patients with COVID-19 were evaluated on initial CT, peak CT, and pre-discharge CT. CT pattern were divided into four types on CT progression. Lesion percentage of pulmonary lobe (lobe score) was graded. Correlation analysis was made between scores and intervals. 53 patients were followed up by CT. Results Among 69 patients, 33.3% exhibited improvement pattern, 65.2% peak pattern, 1.5% deterioration pattern, and 0% fluctuation pattern. The lobe scores were positively correlated with most of intervals. It was more common to observe consolidation, pleural thickening and pleural effusion on the peak CT, and irregular line and reticulation on pre-discharge CT. The peak-initial interval were shortened when the initial CT with consolidation and pleural thickening. The intervals were extended when the irregular lines appeared on peak CT and reticulation on pre-discharge CT. Among 53 follow-up patients, 37.7% showed normal chest CT, and 62.3% showed viral pneumonia remained that mainly included GGO (100.0%) and irregular lines (33.3%). Conclusions COVID-19 displayed different appearances on CT as progressing. The peak pattern was the most common progression pattern. The CT appearances showed closely related to the intervals. The COVID-19 pneumonia can be remained or completely absorbed on CT with follow-up.
Keywords	COVID-19 ; Pneumonia ; Infectious disease medicine ; Multidetector computed tomography ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	616
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: CT appearances, patterns of progression, and follow-up of COVID-19: evaluation on thin-section CT.

Guan, Chun-Shuang / Lv, Zhi-Bin / Li, Jing-Jing / Du, Yan-Ni / Chen, Hui / Cui, Tao / Guo, Ning / Chen, Bu-Dong / Xie, Ru-Ming

Insights into imaging

2021 Volume 12, Issue 1, Page(s) 73

Abstract: Background: To retrospectively analyze CT appearances and progression pattern of COVID-19 during hospitalization, and analyze imaging findings of follow-up on thin-section CT.: Methods: CT findings of 69 patients with COVID-19 were evaluated on ... ...

Abstract	Background: To retrospectively analyze CT appearances and progression pattern of COVID-19 during hospitalization, and analyze imaging findings of follow-up on thin-section CT. Methods: CT findings of 69 patients with COVID-19 were evaluated on initial CT, peak CT, and pre-discharge CT. CT pattern were divided into four types on CT progression. Lesion percentage of pulmonary lobe (lobe score) was graded. Correlation analysis was made between scores and intervals. 53 patients were followed up by CT. Results: Among 69 patients, 33.3% exhibited improvement pattern, 65.2% peak pattern, 1.5% deterioration pattern, and 0% fluctuation pattern. The lobe scores were positively correlated with most of intervals. It was more common to observe consolidation, pleural thickening and pleural effusion on the peak CT, and irregular line and reticulation on pre-discharge CT. The peak-initial interval were shortened when the initial CT with consolidation and pleural thickening. The intervals were extended when the irregular lines appeared on peak CT and reticulation on pre-discharge CT. Among 53 follow-up patients, 37.7% showed normal chest CT, and 62.3% showed viral pneumonia remained that mainly included GGO (100.0%) and irregular lines (33.3%). Conclusions: COVID-19 displayed different appearances on CT as progressing. The peak pattern was the most common progression pattern. The CT appearances showed closely related to the intervals. The COVID-19 pneumonia can be remained or completely absorbed on CT with follow-up.
Language	English
Publishing date	2021-06-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-021-01019-0
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