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Article ; Online: A combined treatment of Proteinase K and biosynthesized ZnO-NPs for eradication of dairy biofilm of sporeformers.

Radwan, Ahmed A / Darwesh, Osama M / Emam, Maha T / Mohamed, Karima A / Shady, Hala M Abu

AIMS microbiology

2022 Volume 8, Issue 4, Page(s) 507–527

Abstract: ... based on proteinase K (Prot-K) coupled with Zinc oxide nanoparticles (ZnO-NPs). Some metal/metal oxide ... K for eradication (removal) of a model biofilm of mixed sporeformers on food-grade stainless steel ... resulted in an 83% reduction in the absorbance of crystal violet-stained biofilm. When Prot-K was mixed ...

Abstract	Biofilms of sporeformers found in the dairy industry are the major contaminants during processing, as they withstand heat and chemical treatment that are used to control microbes. The present work is aimed to remove these resistant forms of bacterial community (biofilm) present in dairy production lines using ecofriendly agents based on proteinase K (Prot-K) coupled with Zinc oxide nanoparticles (ZnO-NPs). Some metal/metal oxide (Ag, CuO and ZnO) NPs were prepared microbially, and ZnO-NPs were characterized as the most effective ones among them. The produced ZnO-NPs were 15-25 nm in size with spherical shape, and FTIR analysis confirmed the presence of proteins and alkanes surrounding particles as capping agents. Application of Prot-K for eradication (removal) of a model biofilm of mixed sporeformers on food-grade stainless steel resulted in an 83% reduction in the absorbance of crystal violet-stained biofilm. When Prot-K was mixed with the biosynthesized NPs ZnO_G240, the reduction increased to 99.19%. This finding could contribute to an efficient cleaning approach combined with CIP to remove the recalcitrant biofilms in dairy production lines.
Language	English
Publishing date	2022-12-19
Publishing country	United States
Document type	Journal Article
ISSN	2471-1888
ISSN (online)	2471-1888
DOI	10.3934/microbiol.2022033
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Article ; Online: The accuracy of the double-K adjustment for third-generation intraocular lens calculation formulas in previous keratorefractive surgery eyes.

Awwad, Shady T / Kilby, Ann / Bowman, R Wayne / Verity, Steven M / Cavanagh, H Dwight / Pessach, Yuval / McCulley, James P

Eye & contact lens

2013 Volume 39, Issue 3, Page(s) 220–227

Abstract: Purpose: To evaluate the effect of the double-K (DK) modification on third-generation formulas ...

Abstract	Purpose: To evaluate the effect of the double-K (DK) modification on third-generation formulas. Methods: Thirty-eight previously myopic and 24 previously hyperopic eyes that underwent phacoemulsification with intraocular lens (IOL) insertion after Laser in situ keratomileusis (LASIK) were evaluated. Pre-LASIK refraction and keratometry, post-LASIK topography, axial length (AL), IOL type and power, and 1-month postphacoemulsification refraction were recorded spherical equivalent after phacoemulsification (SE(postphaco)). Measured corneal power was adjusted using published and validated methods for postmyopic and posthyperopic LASIK. For each eye, and using SE(postphaco), different DK-IOL formulas were used to calculate the corresponding IOL power, the outcome measure, which was compared with the implanted IOL. Results: DK-Holladay 1 yielded the highest Pearson correlation coefficient (PCC), 0.955 for myopes and 0.943 for high myopes (AL>26 mm). Mean error (ME) and mean absolute error (MAE) for myopes for DK Sanders-Retzlaff-Kraff theoretical formula [DK-SRK/T] were 0.44±0.84 D and 0.75±0.61 D for DK-SRK/T compared with -0.04±0.67 D and 0.52±0.40 D for DK-Holladay 1 (P<0.001 and P=0.016, respectively), and 0.03±0.88 and 0.64±0.58 for DK-Hoffer Q. For high myopes, ME and MAE were 0.75±0.81 D and 0.84±0.69 D for DK-SRK/T, and -0.05±0.74 D (P<0.0001) and 0.57±0.45 D (P=0.019) for DK-Holladay 1. About 29% of DK-SRK/T eyes with large AL had MAE>1.5 D, compared with 0% for DK-Holladay 1 and 14% for DK-Hoffer-Q. Eyes with previous hyperopic LASIK faired similarly for all formulas, with similar PCCs, and only 8% in each category with MAE>1.5 D. Conclusions: DK-SRK/T overestimates IOL power in eyes with large AL, especially with concomitant steep pre-lasik keratometry. Among third-generation formulas, DK-Holladay 1 seems more accurate to use in postmyopic LASIK eyes.
MeSH term(s)	Aged ; Axial Length, Eye ; Corneal Topography ; Female ; Humans ; Hyperopia/physiopathology ; Hyperopia/surgery ; Keratomileusis, Laser In Situ ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Male ; Middle Aged ; Myopia/physiopathology ; Myopia/surgery ; Outcome Assessment (Health Care) ; Phacoemulsification/methods ; Refraction, Ocular ; Retrospective Studies
Language	English
Publishing date	2013-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2103049-2
ISSN	1542-233X ; 1542-2321
ISSN (online)	1542-233X
ISSN	1542-2321
DOI	10.1097/ICL.0b013e31828af126
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Article ; Online: A Novel Computational Tool for the Fractional-Order Special Functions Arising from Modeling Scientific Phenomena via Abu-Shady-Kaabar Fractional Derivative.

Abu-Shady, M / Kaabar, Mohammed K A

Computational and mathematical methods in medicine

2022 Volume 2022, Page(s) 2138775

Abstract: Recently, a generalized fractional derivative formulation, known as Abu-Shady-Kaabar fractional ...

Abstract	Recently, a generalized fractional derivative formulation, known as Abu-Shady-Kaabar fractional derivative, is studied in detail which produces satisfactory results that are consistent with conventional definitions of fractional derivative such as Caputo and Riemann-Liouville. To derive the fractional forms of special functions, the generalized fractional derivative is used. The findings demonstrate that the current findings are compatible with Caputo findings. In addition, the fractional solution to the Bessel equation is found. While modeling phenomena in engineering, physical, and health sciences, special functions can be encountered in most modeling scenarios related to electromagnetic waves, hydrodynamics, and other related models. Therefore, there is a need for a computational tool for computing special functions in the sense of fractional calculus. This tool provides a straightforward technique for some fractional-order special functions while modeling these scientific phenomena in science, medicine, and engineering.
MeSH term(s)	Humans ; Mathematics
Language	English
Publishing date	2022-07-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252430-7
ISSN	1748-6718 ; 1748-670X ; 1027-3662
ISSN (online)	1748-6718
ISSN	1748-670X ; 1027-3662
DOI	10.1155/2022/2138775
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Article ; Online: Barriers and Facilitators to Healthcare Access in Adults with Intellectual and Developmental Disorders and Communication Difficulties: an Integrative Review.

Shady, Kathryn / Phillips, Shannon / Newman, Susan

Review journal of autism and developmental disorders

2022 , Page(s) 1–13

Abstract: This integrative review explores the barriers to and facilitators of healthcare access in adults with intellectual and developmental disorders (IDD) and communication difficulties (CD) using Levesque et al.'s conceptual framework of access to health. ... ...

Abstract	This integrative review explores the barriers to and facilitators of healthcare access in adults with intellectual and developmental disorders (IDD) and communication difficulties (CD) using Levesque et al.'s conceptual framework of access to health. IDDs are a group of disorders that occur early in childhood and often involve language dysfunction. CDs are prevalent in adults with IDD. Several themes emerged as barriers to access for adults with IDDs and CDs including health literacy, understanding health information, and screening; fear and negative patient expectations; impaired autonomy; time; accommodation needs; insurance coverage and financial hardship; communication; coordination and continuity of care; and supporter presence and inclusion. Communication between providers, patients, and supporters is a significant barrier for adults with IDD and CD. Supplementary information: The online version contains supplementary material available at 10.1007/s40489-022-00324-8.
Language	English
Publishing date	2022-05-30
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2760390-8
ISSN	2195-7185 ; 2195-7177
ISSN (online)	2195-7185
ISSN	2195-7177
DOI	10.1007/s40489-022-00324-8
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Article ; Online: Effects of foliar application of selenium and potassium-humate on oat growth in Baloza, North Sinai, Egypt.

Hegab, Rehab H / Eissa, Doaa / Abou-Shady, Ahmed

Scientific reports

2022 Volume 12, Issue 1, Page(s) 15119

Abstract: ... Simultaneous application of potassium humate (K-humate) with Se was also investigated in this study. Se ... with K concentrations in seed (K-plant). Application of K-humate with Se increased the bioavailable ... fraction of K-soil; however, it did not increase the bioavailable fraction of K-straw or K-seed ...

Abstract	In this study, the effects of foliar application of selenium (Se) at different concentrations were examined based on changes in several parameters such as nitrogen, phosphorous, and potassium (NPK) concentration in soil and oat plant, oat yield, organic matter in the soil (OMS), non-enzymatic antioxidants, and total phenol content. Chromium (Cr), iron (Fe), manganese (Mn), zinc (Zn), and copper (Cu) concentrations were also assessed in oat straw and seeds. The study complies with local and national guideline. Simultaneous application of potassium humate (K-humate) with Se was also investigated in this study. Se application increased the bioavailability of N and P in soil and their total concentration in the straw and seeds of each plant. Se concentrations were proportional to the amount of phosphorous found in soil (P-soil) but not with K concentrations in seed (K-plant). Application of K-humate with Se increased the bioavailable fraction of K-soil; however, it did not increase the bioavailable fraction of K-straw or K-seed. Although the application of Se alone substantially enhanced yield, the simultaneous application of K-humate showed no additional effect. Moreover, responses of seed yield and plant length were not significant after the application of Se with or without K-humate. OMS and total phenol content were proportional to the application rate of Se with and without K-humate. Non-enzymatic antioxidant content was also proportional to Se concentrations but not proportional to K-humate. The total Se concentrations in the soil, plant straw, and seeds increased with the addition of K-humate. Furthermore, the total Cr concentrations were reduced after the application of Se and K-humate. Fe concentration in the straw and seeds varied from one treatment to another, and Mn concentration was reduced in response to the foliar application of Se and K-humate. Zn concentrations in the straw and seeds of plants were reduced with the application of varying concentrations of Se. Increasing the application rate of Se induced a reduction in the Cu concentration in seeds. In contrast, the simultaneous application of Se and K-humate increased the Cu concentration in seeds.
MeSH term(s)	Avena ; Chromium ; Egypt ; Manganese ; Phenols ; Phosphorus ; Potassium ; Seeds/chemistry ; Selenium ; Soil ; Soil Pollutants/analysis ; Zinc/analysis
Chemical Substances	Phenols ; Soil ; Soil Pollutants ; Chromium (0R0008Q3JB) ; Phosphorus (27YLU75U4W) ; Manganese (42Z2K6ZL8P) ; Selenium (H6241UJ22B) ; Zinc (J41CSQ7QDS) ; Potassium (RWP5GA015D)
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-19229-x
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Article ; Online: A Novel Computational Tool for the Fractional-Order Special Functions Arising from Modeling Scientific Phenomena via Abu-Shady–Kaabar Fractional Derivative

M. Abu-Shady / Mohammed K. A. Kaabar

Computational and Mathematical Methods in Medicine, Vol

2022 Volume 2022

Abstract: Recently, a generalized fractional derivative formulation, known as Abu-Shady–Kaabar fractional ...

Abstract	Recently, a generalized fractional derivative formulation, known as Abu-Shady–Kaabar fractional derivative, is studied in detail which produces satisfactory results that are consistent with conventional definitions of fractional derivative such as Caputo and Riemann-Liouville. To derive the fractional forms of special functions, the generalized fractional derivative is used. The findings demonstrate that the current findings are compatible with Caputo findings. In addition, the fractional solution to the Bessel equation is found. While modeling phenomena in engineering, physical, and health sciences, special functions can be encountered in most modeling scenarios related to electromagnetic waves, hydrodynamics, and other related models. Therefore, there is a need for a computational tool for computing special functions in the sense of fractional calculus. This tool provides a straightforward technique for some fractional-order special functions while modeling these scientific phenomena in science, medicine, and engineering.
Keywords	Computer applications to medicine. Medical informatics ; R858-859.7
Subject code	518
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
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Article ; Online: User Experience Evaluation in Shared Interactive Virtual Reality.

Guertin-Lahoud, Shady / Coursaris, Constantinos K / Sénécal, Sylvain / Léger, Pierre-Majorique

Cyberpsychology, behavior and social networking

2023 Volume 26, Issue 4, Page(s) 263–272

Abstract: Virtual reality (VR) has served the entertainment industry all the way to world-leading museums in delivering engaging experiences through multisensory virtual environments (VEs). Today, the rise of the Metaverse fuels a growing interest in leveraging ... ...

Abstract	Virtual reality (VR) has served the entertainment industry all the way to world-leading museums in delivering engaging experiences through multisensory virtual environments (VEs). Today, the rise of the Metaverse fuels a growing interest in leveraging this technology, bringing along an emerging need to better understand the way different dimensions of VEs, namely social and interactive, impact overall user experience (UX). This between-subject exploratory field study investigates differences in the perceived and lived experience of 28 participants engaging, either individually or in dyads, in a VR experience comprising different levels of interactivity, i.e., passive or active. A mixed methods approach combining conventional UX measures, i.e., psychometric surveys and user interviews, as well as psychophysiological measures, i.e., wearable bio- and motion sensors, allowed for a comprehensive assessment of users' immersive and affective experiences. Results pertaining to the social dimension of the experience reveal that shared VR elicits significantly more positive affect, whereas presence, immersion, flow, and state anxiety are unaffected by the copresence of a real-world partner. Results pertaining to the interactive dimension of the experience suggest that the interactivity afforded by the VE moderates the effect of copresence on users' adaptive immersion and arousal. These results support that VR can be shared with a real-world partner not only without hindering the immersive experience, but also by enhancing positive affect. Hence, in addition to offering methodological directions for future VR field research, this study provides interesting practical insights into guiding VR developers toward optimal multiuser virtual environments.
MeSH term(s)	Humans ; Arousal ; Virtual Reality ; Anxiety ; Anxiety Disorders ; Surveys and Questionnaires
Language	English
Publishing date	2023-04-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2545735-4
ISSN	2152-2723 ; 2152-2715
ISSN (online)	2152-2723
ISSN	2152-2715
DOI	10.1089/cyber.2022.0261
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Article ; Online: Mechanisms involved in the muscle relaxing effects of STW 5 in guinea pig stomach.

Allam, Shady / Krüger, Dagmar / Michel, Klaus / Schnabl, Katharina / Klingenspor, Martin / Schemann, Michael / Annaházi, Anita

Neurogastroenterology and motility

2024 , Page(s) e14761

Abstract: Introduction: The herbal preparation STW 5 ameliorates functional dyspepsia partly by relaxing smooth muscle of the proximal stomach, thus improving gastric accommodation. We explored the unknown pathways responsible for this effect by testing targets ... ...

Abstract	Introduction: The herbal preparation STW 5 ameliorates functional dyspepsia partly by relaxing smooth muscle of the proximal stomach, thus improving gastric accommodation. We explored the unknown pathways responsible for this effect by testing targets known to modulate gastric smooth muscle relaxation. Methods: STW 5-induced relaxation of smooth muscle strips from guinea pig gastric corpus before and after pharmacological interventions were recorded with force transducers in an organ bath. ORAI1 mRNA expression was tested in the proximal stomach. Key results: Blockade of Ca Conclusions & inferences: STW 5 inhibited SOCE, most likely ORAI channels, which are modulated by IP3- and PKC-dependent mechanisms. Our findings impact on the design of drugs to induce muscle relaxation and help identify phytochemicals with similar modes of actions to treat gastrointestinal disturbances.
Language	English
Publishing date	2024-02-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1186328-6
ISSN	1365-2982 ; 1350-1925
ISSN (online)	1365-2982
ISSN	1350-1925
DOI	10.1111/nmo.14761
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Article ; Online: Cardioneuroablation for the Treatment of Hypervagotonic Sinus Node Dysfunction.

Kochar, Arshneel / Taigen, Tyler / Courson, Jeffery / Mayuga, Kenneth / Nakhla, Shady / Wazni, Oussama / Santangeli, Pasquale

JACC. Case reports

2024 Volume 29, Issue 4, Page(s) 102185

Abstract: Hypervagotonic sinus node dysfunction (SND) is a form of SND with sinus bradycardia caused by enhanced vagal tone. Indirect proof of hypervagotonia as the mechanism can be inferred from resolution of bradycardia following atropine infusion. In ... ...

Abstract	Hypervagotonic sinus node dysfunction (SND) is a form of SND with sinus bradycardia caused by enhanced vagal tone. Indirect proof of hypervagotonia as the mechanism can be inferred from resolution of bradycardia following atropine infusion. In symptomatic patients, pacemaker implantation is recommended. We describe cardioneuroablation as a treatment for hypervagotonic SND.
Language	English
Publishing date	2024-01-09
Publishing country	Netherlands
Document type	Case Reports
ISSN	2666-0849
ISSN (online)	2666-0849
DOI	10.1016/j.jaccas.2023.102185
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Article ; Online: Recurrent Instability after the Latarjet Procedure.

Alkhelaifi, Khalid / Alzobi, Osama Z / Mahmoud, Shady A / Zikria, Bashir A

Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews

2023 Volume 7, Issue 12

Abstract: The Latarjet procedure is a favored approach for managing chronic and recurrent dislocation, especially in the presence of bone loss. Although generally yielding excellent results, the procedure carries a 15 to 30% complication rate. Although recurrent ... ...

Abstract	The Latarjet procedure is a favored approach for managing chronic and recurrent dislocation, especially in the presence of bone loss. Although generally yielding excellent results, the procedure carries a 15 to 30% complication rate. Although recurrent instability is a major concern, various complications such as infection, nerve injuries, and hardware impingement can also necessitate revision after a Latarjet procedure. Strategies for addressing this issue include glenoid bone grafting, using autogenous bone grafts from the iliac crest or distal clavicle, and allografts, with fresh lateral distal tibial allografts offering advantages because of their osteochondral nature. In addition, soft-tissue procedures offer another solution for recurrent instability, suitable for patients lacking substantial bone loss or those experiencing multidirectional instability. This review aims to provide a comprehensive overview of the causes and management strategies for recurrent instability following a failed Latarjet procedure.
MeSH term(s)	Humans ; Shoulder Joint/surgery ; Arthroplasty ; Scapula/surgery ; Shoulder Dislocation/surgery ; Bone Transplantation
Language	English
Publishing date	2023-11-27
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	2898328-2
ISSN	2474-7661 ; 1067-151X
ISSN (online)	2474-7661
ISSN	1067-151X
DOI	10.5435/JAAOSGlobal-D-23-00205
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