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Book: Imaging of the pancreas

Armatura, Giulia / Balthazar, Emil J.

acute and chronic pancreatitis ; with 47 tables

(Medical radiology : diagnostic imaging)

2009

Author's details	Emil J. Balthazar ... ed. With Contrib. by G. Armatura
Series title	Medical radiology : diagnostic imaging
Keywords	Pancreatitis / diagnosis ; Pancreas / physiopathology ; Diagnostic Imaging / methods
Language	English
Size	XII, 402 S. : zahlr. Ill., graph. Darst., 27cm
Publisher	Springer
Publishing place	Heidelberg
Publishing country	Germany
Document type	Book
HBZ-ID	HT016016605
ISBN	978-3-540-00281-9 ; 3-540-00281-2 ; 9783540682516 ; 3540682511
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2004 A 6771	order for loan	Magazin
2009 A 4812	order for loan	Magazin

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Article ; Online: Pharmacological and Physiological Correlates of the Bidirectional Fear Phenotype of the Carioca Rats and Other Bidirectionally Selected Lines.

Lages, Yury V / Balthazar, Laura / Krahe, Thomas E / Landeira-Fernandez, J

Current neuropharmacology

2022 Volume 21, Issue 9, Page(s) 1864–1883

Abstract: The Carioca rat lines originated from the selective bidirectional breeding of mates displaying extreme defense responses to contextual conditioned fear. After three generations, two distinct populations could be distinguished: the Carioca High- and Low- ... ...

Abstract	The Carioca rat lines originated from the selective bidirectional breeding of mates displaying extreme defense responses to contextual conditioned fear. After three generations, two distinct populations could be distinguished: the Carioca High- and Low-conditioned Freezing rats, CHF, and CLF, respectively. Later studies identified strong anxiety-like behaviors in the CHF line, while indications of impulsivity and hyperactivity were prominent in the CLF animals. The present review details the physiological and pharmacological-related findings obtained from these lines. The results discussed here point towards a dysfunctional fear circuitry in CHF rats, including alterations in key brain structures and the serotoninergic system. Moreover, data from these animals highlight important alterations in the stress-processing machinery and its associated systems, such as energy metabolism and antioxidative defense. Finally, evidence of an alteration in the dopaminergic pathway in CLF rats is also debated. Thus, accumulating data gathered over the years, place the Carioca lines as significant animal models for the study of psychiatric disorders, especially fear-related ones like anxiety.
MeSH term(s)	Rats ; Animals ; Fear ; Anxiety/metabolism ; Anxiety/psychology ; Brain/metabolism ; Anxiety Disorders/metabolism ; Dopamine/metabolism
Chemical Substances	Dopamine (VTD58H1Z2X)
Language	English
Publishing date	2022-10-12
Publishing country	United Arab Emirates
Document type	Review ; Journal Article
ZDB-ID	2192352-8
ISSN	1875-6190 ; 1570-159X
ISSN (online)	1875-6190
ISSN	1570-159X
DOI	10.2174/1570159X20666221012121534
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Zs.A 6150: Show issues

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Article ; Online: Why and How to Increase Diversity in the Radiology Trainee Workforce.

Klontzas, Michail E / Jean, Jolie / Turner, Valery L / Balthazar, Patricia

Radiographics : a review publication of the Radiological Society of North America, Inc

2022 Volume 42, Issue 3, Page(s) E82–E85

MeSH term(s)	Humans ; Radiography ; Radiology ; Workforce
Language	English
Publishing date	2022-03-18
Publishing country	United States
Document type	Editorial
ZDB-ID	603172-9
ISSN	1527-1323 ; 0271-5333
ISSN (online)	1527-1323
ISSN	0271-5333
DOI	10.1148/rg.220007
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Zs.A 1751: Show issues

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Article ; Online: Results of the 2020 Survey of the American Alliance of Academic Chief Residents in Radiology.

Marquis, Kaitlin M / Hoegger, Mark J / Shetty, Anup S / Bishop, Grace L / Balthazar, Patricia / Gould, Jennifer E / Ballard, David H

Clinical imaging

2023 Volume 98, Page(s) 67–73

Abstract: Rationale and objectives: An annual survey of chief residents in accredited North American radiology programs is conducted by the American Alliance of Academic Chief Residents in Radiology (A: Materials and methods: An online survey was distributed ... ...

Abstract	Rationale and objectives: An annual survey of chief residents in accredited North American radiology programs is conducted by the American Alliance of Academic Chief Residents in Radiology (A Materials and methods: An online survey was distributed to chief residents from 194 Accreditation Council on Graduate Medical Education-accredited radiology residencies. Questions were designed to gather information about residency program practices, benefits, fellowship or advanced interventional radiology (IR) training choices, and the integration of IR training. Subsets of questions focused on the perception of corporatization, non-physician providers (NPPs), and artificial intelligence (AI) in radiology and their relationship to the radiology job market. Results: 174 individual responses from 94 programs were provided, yielding a 48 % program response rate. Extended emergency department coverage has steadily decreased over the last 5 years (2016-2020), however only 52 % of programs have independent overnight call (without attending coverage). Regarding the impact of new integrated IR residencies on training, 42 % indicated there was no appreciable impact on their DR or IR training, while 20 % indicated DR training for IR residents suffered and 19 % indicated IR training for DR residents suffered. Corporatization in radiology was perceived as the biggest potential threat to the future job market. Conclusions: Integration of IR residency did not detrimentally affect DR or IR training in most programs. Radiology resident perception of corporatization, NPPs, and AI may help residency programs shape educational content.
MeSH term(s)	Surveys and Questionnaires ; Radiologists/statistics & numerical data ; Internship and Residency/statistics & numerical data ; Radiology, Interventional ; Professional Corporations ; Artificial Intelligence ; Radiology/education ; Radiology/organization & administration ; Radiology/trends ; United States ; Humans ; Male ; Female
Language	English
Publishing date	2023-02-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2023.02.008
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Zs.A 1469: Show issues

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Article ; Online: The association between the renin-angiotensin system and the hypothalamic-pituitary-adrenal axis in anxiety disorders: A systematic review of animal studies.

Balthazar, L / Lages, Y V M / Romano, V C / Landeira-Fernandez, J / Krahe, T E

Psychoneuroendocrinology

2021 Volume 132, Page(s) 105354

Abstract: Anxiety is characterized as the emotional response in anticipation of a future threat. This hypervigilant state comprehends a cascade of neuroendocrine and physiological processes, involving the renin-angiotensin system (RAS) and hypothalamic-pituitary- ... ...

Abstract	Anxiety is characterized as the emotional response in anticipation of a future threat. This hypervigilant state comprehends a cascade of neuroendocrine and physiological processes, involving the renin-angiotensin system (RAS) and hypothalamic-pituitary-adrenal axis (HPA). Excessive and chronic anxiety may ultimately lead to the development of anxiety disorders. This systematic review aimed to investigate experimental studies using animal models that explored the relationship between RAS and the HPA axis in anxiety disorders. A systematic search was conducted in MEDLINE/PubMed, Embase and Web of Science, and was performed according to PRISMA guidelines. The inclusion criteria was mainly the mention of RAS, HPA axis, and an anxiety disorder in the same study. Quality of studies was evaluated according to the table of risk of bias from SYRCLE. From 12 eligible studies, 7 were included. Research in rats and mice shows that the overactivation of the RAS and HPA axis triggers several neuroendocrine reactions, mainly mediated by AT1 receptors, which promote anxiety-like behaviors and positive feedback for its hyperactivation. On the contrary, the administration of antihypertensive drugs, such as angiotensin AT1 receptor blocker, propitiated the regulation of the RAS and HPA axis, maintaining homeostasis even amid aversive situations. Assessment of risk of bias revealed a pronounced unclear to high risk in several categories, which thus jeopardize the comparability and reproducibility of the results. Nonetheless, the preclinical evidence indicates that the hyperactivation of both RAS and HPA axis during stress exerts deleterious consequences, inducing anxiogenic responses. Moreover, the compiled results show that the modulation of both systems by the administration of AT1 receptor blockers produce anxiolytic effects in animal models and may constitute a new venue for the treatment of anxiety-like disorders.
MeSH term(s)	Animals ; Anxiety ; Anxiety Disorders ; Hypothalamo-Hypophyseal System ; Mice ; Pituitary-Adrenal System ; Rats ; Renin-Angiotensin System ; Reproducibility of Results ; Stress, Psychological
Language	English
Publishing date	2021-07-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	197636-9
ISSN	1873-3360 ; 0306-4530
ISSN (online)	1873-3360
ISSN	0306-4530
DOI	10.1016/j.psyneuen.2021.105354
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Zs.A 1235: Show issues

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Article ; Online: A Review of the State of HIV Nursing Science With Sexual Orientation, Gender Identity/Expression Peoples.

Phillips, J Craig / Hidayat, Jufri / Clark, Kristen D / Melisek, Julia / Balthazar, Monique S / Beck, Albert G D / Moore, Scott E / Dawson-Rose, Carol

The Journal of the Association of Nurses in AIDS Care : JANAC

2021 Volume 32, Issue 3, Page(s) 225–252

Abstract: ... cisgender gay men, and men who have sex with men. Interventions were categorized by societal level (i.e ...

Abstract	Abstract: Throughout the HIV pandemic, nurses have contributed to or led approaches to understanding the effects of HIV disease at individual and societal levels. Nurses have advocated for socially just care for more than a century, and our efforts have created a foundation on which to further build the state of HIV nursing science with sexual orientation and gender identity/expression (SOGI) Peoples. Nurses have also participated in the development of approaches to manage HIV disease for and in collaboration with populations directly affected by the disease. Our inclusive approach was guided by an international human rights legal framework to review the state of nursing science in HIV with SOGI Peoples. We identified articles that provide practice guidance (n = 44) and interventions (n = 26) to address the health concerns of SOGI Peoples and our communities. Practice guidance articles were categorized by SOGI group: SOGI People collectively, bisexual, transgender, cisgender lesbian, women who have sex with women, cisgender gay men, and men who have sex with men. Interventions were categorized by societal level (i.e., individual, family, and structural). Our review revealed opportunities for future HIV nursing science and practices that are inclusive of SOGI Peoples. Through integrated collaborative efforts, nurses can help SOGI communities achieve optimal health outcomes that are based on dignity and respect for human rights.
MeSH term(s)	Female ; Gender Identity ; HIV Infections/drug therapy ; HIV Infections/nursing ; HIV Infections/psychology ; Human Rights ; Humans ; Male ; Nurses/psychology ; Nursing Care ; Post-Exposure Prophylaxis ; Pre-Exposure Prophylaxis ; Sexual Behavior ; Sexual and Gender Minorities
Language	English
Publishing date	2021-05-16
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1159376-3
ISSN	1552-6917 ; 1055-3290
ISSN (online)	1552-6917
ISSN	1055-3290
DOI	10.1097/JNC.0000000000000250
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Zs.A 3748: Show issues

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Article ; Online: Optimizing Fecal Occult Blood Test (FOBT) Colorectal Cancer Screening Using Gut Bacteriome as a Biomarker.

Chowdhury, Moumita Roy / Hone, Karina Gisèle Mac Si / Prévost, Karine / Balthazar, Philippe / Avino, Mariano / Arguin, Mélina / Beaudoin, Jude / Malick, Mandy / Desgagné, Michael / Robert, Gabriel / Scott, Michelle / Dubé, Jean / Laforest-Lapointe, Isabelle / Massé, Eric

Clinical colorectal cancer

2023 Volume 23, Issue 1, Page(s) 22–34.e2

Abstract: Background: Colorectal cancer (CRC) is a major cause of cancer mortality in the world. One of the most widely used screening tests for CRC is the immunochemical fecal occult blood test (iFOBT), which detects human hemoglobin from patient's stool sample. ...

Abstract	Background: Colorectal cancer (CRC) is a major cause of cancer mortality in the world. One of the most widely used screening tests for CRC is the immunochemical fecal occult blood test (iFOBT), which detects human hemoglobin from patient's stool sample. Although it is highly efficient in detecting blood from patients with gastro-intestinal lesions, such as polyps and cancers, the iFOBT has a high rate of false positive discovery. Recent studies suggested gut bacteria as a promising noninvasive biomarker for improving the diagnosis of CRC. In this study, we examined the composition of gut bacteria using iFOBT leftover from patients undergoing screening test along with a colonoscopy. Methods: After collecting data from more than 800 patients, we considered 4 groups for this study. The first and second groups were respectively "healthy" in which the patients had either no blood in their stool or had blood but no lesions. The third and fourth groups of patients had both blood in their stools with precancerous and cancerous lesions and considered either as low-grade and high-grade lesion groups, respectively. An amplification of 16S rRNA (V4 region) gene was performed, followed by sequencing along with various statistical and bioinformatic analysis. Results: We analyzed the composition of the gut bacteriome at phylum, class, genus, and species levels. Although members of the Firmicute phylum increased in the 3 groups compared to healthy patients, the phylum Actinobacteriota was found to decrease. Moreover, Blautia obeum and Anaerostipes hadrus from the phylum Firmicutes were increased and Collinsella aerofaciens from phylum Actinobacteriota was found decreased when healthy group is compared to the patients with high-grade lesions. Finally, among the 5 machine learning algorithms used to perform our analysis, both elastic net (AUC > 0.7) and random forest (AUC > 0.8) performs well in differentiating healthy patients from 3 other patient groups having blood in their stool. Conclusion: Our study integrates the iFOBT screening tool with gut bacterial composition to improve the prediction of CRC lesions.
MeSH term(s)	Humans ; Colorectal Neoplasms/pathology ; Occult Blood ; RNA, Ribosomal, 16S/genetics ; Early Detection of Cancer ; Mass Screening
Chemical Substances	RNA, Ribosomal, 16S
Language	English
Publishing date	2023-10-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2112638-0
ISSN	1938-0674 ; 1533-0028
ISSN (online)	1938-0674
ISSN	1533-0028
DOI	10.1016/j.clcc.2023.10.004
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Zs.A 5798: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: What are the main obstacles to turning foods healthier through probiotics incorporation? a review of functionalization of foods by probiotics and bioactive metabolites.

Penha Rodrigues Pereira, Eliene / Silva da Graça, Juliana / Manfrinato Ferreira, Beatriz / Fasura Balthazar, Celso / Xavier-Santos, Douglas / França Bezerril, Fabrícia / Magnani, Marciane / Sant'Ana, Anderson S

Food research international (Ottawa, Ont.)

2023 Volume 176, Page(s) 113785

Abstract: Functional foods are gaining significant attention from people all over the world. When added to foods, probiotic bacteria can turn them healthier and confer beneficial health effects, such as improving the immune system and preventing cancer, diabetes, ... ...

Abstract	Functional foods are gaining significant attention from people all over the world. When added to foods, probiotic bacteria can turn them healthier and confer beneficial health effects, such as improving the immune system and preventing cancer, diabetes, and cardiovascular disease. However, adding probiotics to foods is a challenging task. The processing steps often involve high temperatures, and intrinsic food factors, such as pH, water activity, dissolved oxygen, post-acidification, packaging, and cold storage temperatures, can stress the probiotic strain and impact its viability. Moreover, it is crucial to consider these factors during food product development to ensure the effectiveness of the probiotic strain. Among others, techniques such as microencapsulation and lyophilization, have been highlighted as industrial food functionalization strategies. In this review, we present and discuss alternatives that may be used to functionalize foods by incorporating probiotics and/or delivering bioactive compounds produced by probiotics. We also emphasize the main challenges in different food products and the technological characteristics influencing them. The knowledge available here may contribute to overcoming the practical obstacles to food functionalization with probiotics.
MeSH term(s)	Humans ; Probiotics ; Functional Food ; Bacteria ; Food Handling
Language	English
Publishing date	2023-12-02
Publishing country	Canada
Document type	Journal Article ; Review
ZDB-ID	1111695-x
ISSN	1873-7145 ; 0963-9969
ISSN (online)	1873-7145
ISSN	0963-9969
DOI	10.1016/j.foodres.2023.113785
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Article: Pancreatitis associated with pancreatic carcinoma. Preoperative diagnosis: role of CT imaging in detection and evaluation.

Balthazar, E J

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

2005 Volume 5, Issue 4-5, Page(s) 330–344

Abstract: The combined occurrence of pancreatic carcinoma with acute or chronic pancreatitis is seldom seen in medical practice, but when present it is a challenging dilemma, plagued by confusing overlapping clinical findings and pitfalls in diagnostic imaging ... ...

Abstract	The combined occurrence of pancreatic carcinoma with acute or chronic pancreatitis is seldom seen in medical practice, but when present it is a challenging dilemma, plagued by confusing overlapping clinical findings and pitfalls in diagnostic imaging tests. This article reviews the presumptive pathophysiological aspects of this relationship, the perplexing clinical presentations and the advantages and limitations of the noninvasive imaging examinations. The role of state-of-the-art CT imaging in screening patients with acute and chronic pancreatitis is emphasized and the impute of additional more invasive tests in detecting pancreatic tumors in this cohort of patients is reviewed. The habitual use of CT imaging, followed when needed by complementary examinations, can improve on previously reported low detection rates and hopefully decrease the number of exploratory laparatomies and unnecessary major pancreatic surgical resections.
MeSH term(s)	Acute Disease ; Adenocarcinoma/complications ; Adenocarcinoma/diagnosis ; Adult ; Aged ; Chronic Disease ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms/complications ; Pancreatic Neoplasms/diagnosis ; Pancreatitis/complications ; Pancreatitis/diagnosis ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2005
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2056680-3
ISSN	1424-3911 ; 1424-3903
ISSN (online)	1424-3911
ISSN	1424-3903
DOI	10.1159/000086868
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Article ; Online: Major depressive episode with insomnia and excessive daytime sleepiness: A more homogeneous and severe subtype of depression.

Maruani, Julia / Boiret, Charlotte / Leseur, Jeanne / Romier, Alix / Bazin, Balthazar / Stern, Emilie / Lejoyeux, Michel / Geoffroy, Pierre A

Psychiatry research

2023 Volume 330, Page(s) 115603

Abstract: Previous studies have noted the crucial role of excessive daytime sleepiness (EDS) in the course of depressive illness, and more recently, a few studies documented its strong associations with an increased risk of suicide. While insomnia is associated ... ...

Abstract	Previous studies have noted the crucial role of excessive daytime sleepiness (EDS) in the course of depressive illness, and more recently, a few studies documented its strong associations with an increased risk of suicide. While insomnia is associated with heightened emotional reactivity, suicidal behaviors, and increased relapses and recurrence. Our main hypothesis is that major depressive episodes (MDE) with insomnia and EDS are associated with more severe manifestations of depression. However, to date, no study has directly compared MDE with insomnia without EDS (Ins), and MDE with insomnia with EDS (InsEDS) using both subjective biomarkers (administration of self-assessment questionnaires for psychiatric evaluation and sleep complaints) and objective biomarkers (of sleep and circadian rhythms (using actigraphy). The InsEDS group, compared to the Ins group, exhibited significantly increased suicidal ideation, larger seasonal impacts on mood, alterations in sleep duration, weight, appetite, energy levels, and social activities throughout the year. Furthermore, they had significant delayed onset of daily activity measured with actigraphy. These findings provided new insights into the link between suicide, sleep, alertness, and biological clock. They also hold significant implications for identifying individuals with more severe depressive manifestations and for developing tailored and personalized therapeutic strategies.
MeSH term(s)	Humans ; Sleep Initiation and Maintenance Disorders/complications ; Depression/complications ; Depressive Disorder, Major/complications ; Disorders of Excessive Somnolence/complications ; Biomarkers
Chemical Substances	Biomarkers
Language	English
Publishing date	2023-11-11
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2023.115603
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