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  1. Article ; Online: Predicting origin for bone metastatic cancer using deep learning-based pathology.

    Fang, Mengjie / Wang, Zipei / Tian, Jie / Dong, Di

    EBioMedicine

    2023  Volume 88, Page(s) 104449

    MeSH term(s) Humans ; Deep Learning ; Bone Neoplasms/diagnosis
    Language English
    Publishing date 2023-01-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2023.104449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Molecular Wiring of Electrocatalytic Nitrate reduction to Ammonia and Water Oxidation by Iron-Coordinated Macroporous Conductive Networks.

    Li, Mengjie / Wen, Yingke / Fang, Yanjie / Shan, Bing

    Angewandte Chemie (International ed. in English)

    2024  , Page(s) e202405746

    Abstract: Developing stable electrocatalysts with accessible isolated sites is desirable but highly challenging due to metal agglomeration and low surface stability of host materials. Here we report a general approach for synthesis of single-site Fe ... ...

    Abstract Developing stable electrocatalysts with accessible isolated sites is desirable but highly challenging due to metal agglomeration and low surface stability of host materials. Here we report a general approach for synthesis of single-site Fe electrocatalysts by integrating a solvated Fe complex in conductive macroporous organic networks through redox-active coordination linkages. Electrochemical activation of the electrode exposes high-density coordinately unsaturated Fe sites for efficient adsorption and conversion of reaction substrates such as NO3- and H2O. Using the electrode with isolated active Fe sites, electrocatalytic NO3- reduction and H2O oxidation can be coupled in a single cell to produce NH3 and O2 at Faradaic efficiencies of 97% and 100%, respectively. The electrode exhibits excellent robustness in electrocatalysis for 200 hours with small decrease in catalytic efficiencies. Both the maximized Fe-site efficiency and the microscopic localization effect of the conductive organic matrix contribute to the high catalytic performances, which provides new understandings in tuning the efficiencies of metal catalysts for high-performance electrocatalytic cells.
    Language English
    Publishing date 2024-04-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202405746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effective Bidirectional Mott-Schottky Catalysts Derived from Spent LiFePO

    Zhang, Mengjie / Zhang, Zhongshuai / Wu, Fang / Wang, Mengxiao / Yu, Xiaoyuan

    Small (Weinheim an der Bergstrasse, Germany)

    2024  , Page(s) e2309146

    Abstract: It is deemed as a tough yet profound project to comprehensively cope with a range of detrimental problems of lithium-sulfur batteries (LSBs), mainly pertaining to the shuttle effect of lithium polysulfides (LiPSs) and sluggish sulfur conversion. Herein, ... ...

    Abstract It is deemed as a tough yet profound project to comprehensively cope with a range of detrimental problems of lithium-sulfur batteries (LSBs), mainly pertaining to the shuttle effect of lithium polysulfides (LiPSs) and sluggish sulfur conversion. Herein, a Co
    Language English
    Publishing date 2024-02-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202309146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Predicting origin for bone metastatic cancer using deep learning-based pathology

    Mengjie Fang / Zipei Wang / Jie Tian / Di Dong

    EBioMedicine, Vol 88, Iss , Pp 104449- (2023)

    2023  

    Keywords Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Non-invasively predicting response to neoadjuvant chemotherapy in gastric cancer via deep learning radiomics.

    Fang, Mengjie / Tian, Jie / Dong, Di

    EClinicalMedicine

    2022  Volume 46, Page(s) 101380

    Language English
    Publishing date 2022-04-07
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2022.101380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The outbreak of Drupella snails and its catastrophic effects on coral reefs

    Fang Zhang / Xiwang Jia / Zhenni Lin / Yiyi Jiang / Mengjie Qu

    Frontiers in Marine Science, Vol

    a comprehensive review

    2024  Volume 10

    Abstract: The recurring outbreaks of Drupella snails are a significant threat to coral reef ecosystems on a global scale. However, research on Drupella snails is currently very fragmentary. This article explores the ecological impacts and mitigation methods of ... ...

    Abstract The recurring outbreaks of Drupella snails are a significant threat to coral reef ecosystems on a global scale. However, research on Drupella snails is currently very fragmentary. This article explores the ecological impacts and mitigation methods of Drupella snails and its outbreaks, and draws the following main conclusions. 1) Drupella snails inhabit the tropical oceans of the Indo-Pacific, utilizing their specialized radula to feed on coral polyps, and they predominantly spawn during summer, attaching egg capsules onto coral skeletons. 2) An outbreak of Drupella snails is defined by a density of > 2 ind/m2, but large aggregations alone do not necessarily indicate an outbreak. 3) The damage of coral reef ecosystem is the primary cause of Drupella snail outbreaks, with the hypotheses of “terrestrial nutrient input” and “overfishing of predator” being widely accepted but not fully explaining all outbreak events. 4) Countering Drupella snail outbreaks involves improving the health of coral reef ecosystems, protected areas, biological control and manual removal, though manual removal is the most direct and effective in short-term. 5) The understanding of the physiological and ecological characteristics of Drupella snails is inadequate at present, with larval development and population ecology being areas of particular under-investigation. 6) Studies of Drupella snail outbreaks have focused mainly on mid-outbreak stages, with little attention to early warnings beforehand or adverse outcomes afterwards. Despite significant challenges, addressing knowledge gaps in the biology of Drupella snails is crucial to determine the true causes of their outbreaks and identify corresponding solutions.
    Keywords coral reef deterioration ; coral predator ; corallivorous gastropod ; outbreak hallmark ; mitigation strategies ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 590
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Charge Photoaccumulation in Covalent Polymer Networks for Boosting Photocatalytic Nitrate Reduction to Ammonia.

    He, Xinjia / Wen, Yingke / Fang, Yanjie / Li, Mengjie / Shan, Bing

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  , Page(s) e2401878

    Abstract: In the design of photoelectrocatalytic cells, a key element is effective photogeneration of electron-hole pairs to drive redox activation of catalysts. Despite recent progress in photoelectrocatalysis, experimental realization of a high-performance ... ...

    Abstract In the design of photoelectrocatalytic cells, a key element is effective photogeneration of electron-hole pairs to drive redox activation of catalysts. Despite recent progress in photoelectrocatalysis, experimental realization of a high-performance photocathode for multi-electron reduction of chemicals, such as nitrate reduction to ammonia, has remained a challenge due to difficulty in obtaining efficient electrode configurations for extraction of high-throughput electrons from absorbed photons. This work describes a new design for catalytic photoelectrodes using chromophore assembly-functionalized covalent networks for boosting eight-electron reduction of nitrate to ammonia. Upon sunlight irradiation, the photoelectrode stores a mass of reducing equivalents at the photoexcited chromophore assembly for multielectron reduction of a copper catalyst, enabling efficient nitrate reduction to ammonia. By introducing the new photoelectrode structure, it is demonstrated that the electronic interplay between charge photo-accumulating assembly and multi-electron redox catalysts can be optimized to achieve proper balance between electron transfer dynamics and thermodynamic output of photoelectrocatalytic systems.
    Language English
    Publishing date 2024-04-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202401878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Non-invasively predicting response to neoadjuvant chemotherapy in gastric cancer via deep learning radiomics

    Mengjie Fang / Jie Tian / Di Dong

    EClinicalMedicine, Vol 46, Iss , Pp 101380- (2022)

    2022  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Cumulative residual cholesterol predicts the risk of cardiovascular disease in the general population aged 45 years and older.

    Zhao, Mengjie / Xiao, Mengli / Tan, Qin / Ji, Jinjin / Lu, Fang

    Lipids in health and disease

    2024  Volume 23, Issue 1, Page(s) 19

    Abstract: Background: Numerous studies have affirmed a robust correlation between residual cholesterol (RC) and the occurrence of cardiovascular disease (CVD). However, the current body of literature fails to adequately address the link between alterations in RC ... ...

    Abstract Background: Numerous studies have affirmed a robust correlation between residual cholesterol (RC) and the occurrence of cardiovascular disease (CVD). However, the current body of literature fails to adequately address the link between alterations in RC and the occurrence of CVD. Existing studies have focused mainly on individual RC values. Hence, the primary objective of this study is to elucidate the association between the cumulative RC (Cum-RC) and the morbidity of CVD.
    Methods: The changes in RC were categorized into a high-level fast-growth group (Class 1) and a low-level slow-growth group (Class 2) by K-means cluster analysis. To investigate the relationship between combined exposure to multiple lipids and CVD risk, a weighted quantile sum (WQS) regression analysis was employed. This analysis involved the calculation of weights for total cholesterol (TC), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), which were used to effectively elucidate the RC.
    Results: Among the cohort of 5,372 research participants, a considerable proportion of 45.94% consisted of males, with a median age of 58. In the three years of follow-up, 669 participants (12.45%) had CVD. Logistic regression analysis revealed that Class 2 individuals had a significantly reduced risk of developing CVD compared to Class 1. The probability of having CVD increased by 13% for every 1-unit increase in the Cum-RC according to the analysis of continuous variables. The restricted cubic spline (RCS) analysis showed that Cum-RC and CVD risk were linearly related (P for nonlinearity = 0.679). The WQS regression results showed a nonsignificant trend toward an association between the WQS index and CVD incidence but an overall positive trend, with the greatest contribution from TC (weight = 0.652), followed by LDL (weight = 0.348).
    Conclusion: Cum-RC was positively and strongly related to CVD risk, suggesting that in addition to focusing on traditional lipid markers, early intervention in patients with increased RC may further reduce the incidence of CVD.
    MeSH term(s) Male ; Humans ; Cardiovascular Diseases/epidemiology ; Cholesterol, HDL ; Cholesterol, LDL ; Cholesterol ; Incidence ; Risk Factors
    Chemical Substances Cholesterol, HDL ; Cholesterol, LDL ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091381-3
    ISSN 1476-511X ; 1476-511X
    ISSN (online) 1476-511X
    ISSN 1476-511X
    DOI 10.1186/s12944-023-02000-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction to: Spectral CT-based nomogram for preoperative prediction of perineural invasion in locally advanced gastric cancer: a prospective study.

    Li, Jing / Xu, Shuning / Wang, Yi / Fang, Mengjie / Ma, Fei / Xu, Chunmiao / Li, Hailiang

    European radiology

    2023  Volume 33, Issue 7, Page(s) 5207

    Language English
    Publishing date 2023-04-27
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-023-09646-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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