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  1. Article ; Online: Emerging role of cardiac MRI in acute pericarditis.

    Al-Ani, Mohammad / Keeley, Ellen C

    International journal of cardiology

    2022  Volume 359, Page(s) 122–123

    MeSH term(s) Acute Disease ; Cardiac Tamponade ; Humans ; Magnetic Resonance Imaging ; Pericarditis/diagnostic imaging ; Radiography
    Language English
    Publishing date 2022-04-15
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2022.04.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction.

    Stein, Andrew P / Harder, Jonathan / Holmes, Henry R / Merz, C Noel Bairey / Pepine, Carl J / Keeley, Ellen C

    Journal of the American Heart Association

    2024  Volume 13, Issue 4, Page(s) e032137

    Abstract: Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. There are data to suggest that coronary microvascular dysfunction, in some cases, may be genetically determined. We present an ... ...

    Abstract Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. There are data to suggest that coronary microvascular dysfunction, in some cases, may be genetically determined. We present an updated review of single nucleotide polymorphisms in coronary microvascular dysfunction.
    MeSH term(s) Humans ; Coronary Circulation ; Polymorphism, Single Nucleotide ; Myocardial Ischemia ; Coronary Vessels/diagnostic imaging ; Microcirculation ; Coronary Artery Disease/genetics
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.032137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Circulating Biomarkers in Coronary Microvascular Dysfunction.

    Chakrala, Teja / Prakash, Roshni / Valdes, Carlos / Pepine, Carl J / Keeley, Ellen C

    Journal of the American Heart Association

    2023  Volume 12, Issue 12, Page(s) e029341

    Abstract: Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in the diagnosis and management of coronary ... ...

    Abstract Coronary microvascular dysfunction is an underdiagnosed pathologic process that is associated with adverse clinical outcomes. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in the diagnosis and management of coronary microvascular dysfunction. We present an updated review of circulating biomarkers in coronary microvascular dysfunction representing key pathologic processes, including inflammation, endothelial dysfunction, oxidative stress, coagulation, and other mechanisms.
    MeSH term(s) Humans ; Coronary Artery Disease ; Biomarkers ; Myocardial Ischemia ; Inflammation ; Oxidative Stress ; Coronary Vessels/diagnostic imaging
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-06-10
    Publishing country England
    Document type Journal Article ; Review ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.122.029341
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  4. Article ; Online: CXCL5 gene polymorphisms and coronary collateralization.

    Keeley, Ellen C / Blotner, Michael R / Lipson, Lewis C / Mehrad, Borna

    American heart journal plus : cardiology research and practice

    2022  Volume 23, Page(s) 100220

    Abstract: Background: The presence of coronary collateralization is heterogenous, even amongst those with similar degrees of epicardial coronary artery stenoses. We hypothesized that genetic variation of CXCL5, a chemokine that mediates angiogenesis, is ... ...

    Abstract Background: The presence of coronary collateralization is heterogenous, even amongst those with similar degrees of epicardial coronary artery stenoses. We hypothesized that genetic variation of CXCL5, a chemokine that mediates angiogenesis, is associated with coronary collateralization.
    Methods: We genotyped subjects undergoing coronary angiography for single nucleotide polymorphisms of CXCL5 and determined the presence of spontaneously visible coronary collaterals.
    Results: Subjects with collaterals had less angina (46 % vs 59 %, p = 0.006), and prior percutaneous coronary intervention (34 % vs 47 %, p = 0.010), and more hyperlipidemia (90 % vs 82 %, p = 0.018), peripheral arterial disease (25 % vs 17 %, p = 0.041), congestive heart failure (16 % vs 8 %, p = 0.007), and multi-vessel coronary artery disease (41 % vs 24 %, p = 0.0001) compared to those without collaterals. Multi-vessel disease and hyperlipidemia were positive predictors of angiographically visible collaterals while being a carrier of the CXCL5 polymorphism was a negative predictor.
    Conclusions: Coronary collateralization may, at least in part, be genetically determined.
    Language English
    Publishing date 2022-10-17
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6022
    ISSN (online) 2666-6022
    DOI 10.1016/j.ahjo.2022.100220
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  5. Article ; Online: Concomitant coronary microvascular dysfunction and spontaneous coronary artery dissection resulting in ST-segment elevation myocardial infarction.

    Matthia, Eldon / Pepine, Carl J / Keeley, Ellen C

    Journal of cardiology cases

    2021  Volume 25, Issue 2, Page(s) 76–78

    Abstract: We report a patient with angina and no flow-limiting epicardial coronary artery disease who presented with recurrent spontaneous coronary artery dissection resulting in an acute ST-elevation myocardial infarction and evidence of coronary microvascular ... ...

    Abstract We report a patient with angina and no flow-limiting epicardial coronary artery disease who presented with recurrent spontaneous coronary artery dissection resulting in an acute ST-elevation myocardial infarction and evidence of coronary microvascular dysfunction on coronary angiography. We review each condition's pathophysiology and provide a review of the literature for reported associations between these disease processes. <
    Language English
    Publishing date 2021-07-22
    Publishing country Japan
    Document type Case Reports
    ISSN 1878-5409
    ISSN (online) 1878-5409
    DOI 10.1016/j.jccase.2021.06.014
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  6. Article ; Online: Acute myocarditis during the COVID-19 pandemic: A single center experience.

    Petersen, Matthew / Mehrad, Borna / Keeley, Ellen C

    American heart journal plus : cardiology research and practice

    2021  Volume 5, Page(s) 100030

    Abstract: Objective: We sought to compare the occurrence and characteristics of patients with acute myocarditis admitted during the coronavirus disease 2019 pandemic to those admitted prior.: Design: We performed a retrospective chart review of patients with ... ...

    Abstract Objective: We sought to compare the occurrence and characteristics of patients with acute myocarditis admitted during the coronavirus disease 2019 pandemic to those admitted prior.
    Design: We performed a retrospective chart review of patients with the primary discharge diagnosis of acute myocarditis from September 1st 2017 through August 31st 2020.
    Results: We identified 67 patients, 45 (67%) admitted pre-pandemic, and 22 (33%) during the pandemic. Rate of admissions for acute myocarditis was 1.5/month [95% CI 1.04-1.95] pre-pandemic, and 3.7/month [95% CI 2.36-4.97] (p < 0.001) during the first 6 months of the pandemic. Of the 22 patients admitted during the pandemic, 10 (45%) tested positive for SARS-CoV-2. Patients who tested positive for SARS-CoV-2 were older and had lower peak troponin levels.
    Conclusions: During the pandemic, less than half of the patients admitted with acute myocarditis tested positive for SARS-CoV-2. Patients who tested positive were older and had lower peak troponin levels.
    Language English
    Publishing date 2021-06-24
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6022
    ISSN (online) 2666-6022
    DOI 10.1016/j.ahjo.2021.100030
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  7. Article ; Online: Acromegaly-Induced Cardiomyopathy Masquerading as an Acute Coronary Syndrome.

    Patel, Sandip / Minish, Jordan M / Keeley, Ellen C

    The American journal of medicine

    2020  Volume 134, Issue 1, Page(s) e51–e52

    MeSH term(s) Acromegaly/complications ; Acute Coronary Syndrome/physiopathology ; Cardiomyopathies/complications ; Diagnosis, Differential ; Electrocardiography/methods ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged
    Language English
    Publishing date 2020-07-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2020.05.045
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Unplanned Readmissions After Acute Myocardial Infarction: 1-Year Trajectory Following Discharge From a Safety Net Hospital.

    Shah, Ishan T / Keeley, Ellen C

    Critical pathways in cardiology

    2019  Volume 18, Issue 2, Page(s) 72–74

    Abstract: Background: Financial penalties rendered by the Centers for Medicare and Medicaid Services have brought about new challenges for safety net hospitals that serve a vulnerable patient population with risk factors associated with high readmission rates. ... ...

    Abstract Background: Financial penalties rendered by the Centers for Medicare and Medicaid Services have brought about new challenges for safety net hospitals that serve a vulnerable patient population with risk factors associated with high readmission rates. Our goal was to determine the 1-year trajectory of unplanned readmissions in post-myocardial infarction (MI) patients, and to identify factors associated with readmission.
    Methods: A total of 261 acute MI patients admitted from April 2015 to April 2016 were evaluated in a multidisciplinary cardiology clinic within 10 days of hospital discharge and baseline characteristics and medical comorbidities were collected. Readmission and mortality data were obtained at 1 year through chart review and telephone follow-up.
    Results: At 1 year, there were 90 (34%) unplanned readmissions of which half were for noncardiac diagnoses. Of these, 69 patients (77%) were readmitted once, 16 (18%) were readmitted twice, 2 (2%) were readmitted 3 times, and 3 (3%) were readmitted 4 times over the subsequent year. Cardiac causes of 1-year readmission included recurrent MI in 23 (9%) and decompensated heart failure in 18 (7%) patients. Depressed left ventricular systolic function (hazard ratio, 2.23; 95% confidence interval, 2.00-2.44; P = 0.0003) and diabetes mellitus (hazard ratio, 1.60; 95% confidence interval, 1.38-1.82; P = 0.029) were associated with a significantly higher risk of readmission at 1 year.
    Conclusion: Following acute MI, patients are readmitted for cardiac and noncardiac diagnoses well beyond the 30-day mark. This is likely a function of the vulnerability of the patient population rather than a reflection of the medical care provided. More frequent surveillance may attenuate this problem.
    MeSH term(s) Comorbidity ; Diabetes Mellitus/epidemiology ; Female ; Heart Failure/epidemiology ; Heart Failure/therapy ; Humans ; Male ; Middle Aged ; Myocardial Infarction/economics ; Myocardial Infarction/mortality ; Myocardial Infarction/therapy ; Patient Discharge/statistics & numerical data ; Patient Readmission/economics ; Patient Readmission/statistics & numerical data ; Recurrence ; Risk Assessment/methods ; Risk Factors ; Safety-net Providers/methods ; Safety-net Providers/statistics & numerical data ; United States/epidemiology
    Language English
    Publishing date 2019-05-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2079676-6
    ISSN 1535-2811 ; 1535-282X
    ISSN (online) 1535-2811
    ISSN 1535-282X
    DOI 10.1097/HPC.0000000000000170
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Varicella Zoster Virus-Induced Complete Heart Block.

    Singhal, Ruchi / Jin, Phoebe / Nassereddin, Ali T / Lopez, Jonathan E / Keeley, Ellen C

    The American journal of medicine

    2022  Volume 136, Issue 4, Page(s) e63–e64

    MeSH term(s) Humans ; Herpesvirus 3, Human ; Chickenpox ; Heart Block/diagnosis ; Heart Block/etiology ; Herpes Zoster/complications ; Herpes Zoster/diagnosis
    Language English
    Publishing date 2022-12-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2022.12.013
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Recurrent Lethal Allergic Coronary Vasospasm.

    Elzeneini, Mohammed / Aalaei-Andabili, Seyed Hossein / Keeley, Ellen C

    The American journal of medicine

    2020  Volume 133, Issue 12, Page(s) e731–e732

    MeSH term(s) Aged ; Contrast Media/adverse effects ; Coronary Vasospasm/chemically induced ; Echocardiography ; Fatal Outcome ; Fluorocarbons/adverse effects ; Hemorrhage/complications ; Humans ; Kounis Syndrome/pathology ; Lung Diseases/complications ; Lung Diseases/pathology ; Male
    Chemical Substances Contrast Media ; Definity ; Fluorocarbons
    Language English
    Publishing date 2020-06-01
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2020.04.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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