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  1. Article ; Online: SER-109 for Recurrent Clostridioides difficile Infection.

    Blot, Mathieu / Piroth, Lionel

    The New England journal of medicine

    2022  Volume 386, Issue 20, Page(s) 1957

    MeSH term(s) Clostridioides difficile ; Clostridium Infections/drug therapy ; Humans ; Microbiota
    Language English
    Publishing date 2022-05-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2202493
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    Ua VI Zs.34: Show issues Location:
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  2. Article ; Online: CMV Infection and Lymphopenia: Warning Markers of

    Eberl, Isabelle / Binquet, Christine / Guilloteau, Adrien / Legendre, Mathieu / Dalle, Frederic / Piroth, Lionel / Tinel, Claire / Blot, Mathieu

    Transplant international : official journal of the European Society for Organ Transplantation

    2024  Volume 37, Page(s) 12192

    Abstract: ... ...

    Abstract Pneumocystis
    MeSH term(s) Humans ; Pneumonia, Pneumocystis/diagnosis ; Pneumonia, Pneumocystis/complications ; Pneumonia, Pneumocystis/drug therapy ; Case-Control Studies ; Kidney Transplantation/adverse effects ; Pneumocystis carinii ; Creatinine ; Cytomegalovirus Infections/complications ; Cytomegalovirus Infections/diagnosis ; Cytomegalovirus Infections/epidemiology ; Risk Factors ; Lymphopenia/complications ; Thrombocytopenia/complications ; Transplant Recipients ; Retrospective Studies
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2024.12192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2358: Show issues Location:
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  3. Article: The evolution of lung computed tomography findings in COVID-19 from 2020 to 2023: more signs of co-infection.

    Romagny, Sabrina / Sixt, Thibault / Moretto, Florian / Ray, Patrick / Ricolfi, Frederic / Piroth, Lionel / Blot, Mathieu

    ERJ open research

    2024  Volume 10, Issue 1

    Abstract: Significant changes were observed in the lung imaging of hospitalised COVID-19 patients from 2020 to 2023, with the emergence of more signs of co- ... ...

    Abstract Significant changes were observed in the lung imaging of hospitalised COVID-19 patients from 2020 to 2023, with the emergence of more signs of co-infection
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00727-2023
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  4. Article ; Online: Empiric Antibiotics in Hospitalized Pneumonia: Discontinuation Is Better than De-escalation.

    Blot, Mathieu / Dinh, Aurélien

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 74, Issue 4, Page(s) 749–750

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Cross Infection/drug therapy ; Hospitalization ; Humans ; Pneumonia/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-06-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciab544
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  5. Article ; Online: Re: Predicting critical illness on initial diagnosis of COVID-19 based on easily-obtained clinical variables.

    Moretto, Florian / Sixt, Thibault / Blot, Mathieu / Piroth, Lionel

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2022  Volume 28, Issue 8, Page(s) 1161–1162

    MeSH term(s) COVID-19/diagnosis ; Critical Illness ; Humans ; SARS-CoV-2 ; Severity of Illness Index
    Language English
    Publishing date 2022-05-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2022.01.015
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    Zs.MO 284: Show issues

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  6. Article: Intractable liver abscess and positive string test: Think

    Godon, Jeanne / Das-Neves, Sylvia / Blanchot, Thomas / Piroth, Lionel / Blot, Mathieu

    IDCases

    2022  Volume 27, Page(s) e01447

    Language English
    Publishing date 2022-02-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2022.e01447
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  7. Article ; Online: Addition of daptomycin for the treatment of pneumococcal meningitis: protocol for the AddaMAP study.

    Chavanet, Pascal / Fournel, Isabelle / Bourredjem, Abderrahmane / Piroth, Lionel / Blot, Mathieu / Sixt, Thibault / Binquet, Christine

    BMJ open

    2023  Volume 13, Issue 7, Page(s) e073032

    Abstract: Background: The leading cause of acute bacterial meningitis in adults is : Methods and analysis: The AddaMAP trial is a phase II, open-label, Simon's two-stage, multicentre trial that has been designed to assess the efficacy and safety of adding ... ...

    Abstract Background: The leading cause of acute bacterial meningitis in adults is
    Methods and analysis: The AddaMAP trial is a phase II, open-label, Simon's two-stage, multicentre trial that has been designed to assess the efficacy and safety of adding daptomycin (10 mg/kg/d for 8 days) to the recommended treatment (corticosteroids+third generation cephalosporin) in adults with confirmed pneumococcal meningitis. The main endpoint is the disability-free survival (defined as modified Rankin Scale mRS≤2) at day 30. Secondary outcomes are overall mortality, disability at D30 and D90 (mRS, Glasgow Coma Scale and Glasgow Outcome Scales, mini-mental score), hearing loss (Hearing Handicap Inventory Test at D30 and D90, routine audiometric test and Hearing-it test at D30), and quality of life (12-item Short Form Survey and WHO QOL BREF). Seventy-two analysable patients are required.
    Ethics and dissemination: The study protocol was approved by the Institutional Review Board of the IDF 1 of the ethics committee on 16 January 2018, and authorisation was obtained from the Agence Nationale de Securité des Médicaments et des Produits de Santé on 22 September 2017. The results will be submitted for publication in a peer-reviewed journal.
    Trial registration number: NCT03480191.
    MeSH term(s) Adult ; Humans ; Anti-Bacterial Agents/therapeutic use ; Daptomycin/therapeutic use ; Meningitis, Pneumococcal/drug therapy ; Meningitis, Pneumococcal/cerebrospinal fluid ; Meningitis, Pneumococcal/complications ; Multicenter Studies as Topic ; Quality of Life ; Streptococcus pneumoniae ; Clinical Trials, Phase II as Topic
    Chemical Substances Anti-Bacterial Agents ; Daptomycin (NWQ5N31VKK)
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-073032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Is IL-6 the Right Target in COVID-19 Severe Pneumonia?

    Blot, Mathieu / Bourredjem, Abderrahmane / Binquet, Christine / Piroth, Lionel

    American journal of respiratory and critical care medicine

    2020  Volume 203, Issue 1, Page(s) 139–140

    MeSH term(s) Antibodies, Monoclonal, Humanized ; COVID-19 ; Humans ; Interleukin-6 ; SARS-CoV-2 ; Severity of Illness Index
    Chemical Substances Antibodies, Monoclonal, Humanized ; Interleukin-6
    Keywords covid19
    Language English
    Publishing date 2020-09-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202007-2924LE
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  9. Article ; Online: Children Hospitalized With Respiratory Syncytial Virus Infection: A Pre Versus Late COVID-19 Pandemic Comparison.

    Solus, Astrid / Huet, Frederic / Perez-Martin, Stephanie / Verney, Cindy / Auvray, Christelle / Binquet, Christine / Piroth, Lionel / Blot, Mathieu

    The Pediatric infectious disease journal

    2023  Volume 43, Issue 3, Page(s) e110–e113

    Abstract: Our study aimed to compare children under 5 years hospitalized with respiratory syncytial virus in prepandemic and late-pandemic periods. We included 209 children at the Dijon University Hospital (France). We observed a nearly 3-fold increase in the ... ...

    Abstract Our study aimed to compare children under 5 years hospitalized with respiratory syncytial virus in prepandemic and late-pandemic periods. We included 209 children at the Dijon University Hospital (France). We observed a nearly 3-fold increase in the number of cases in the late period, with older children, but less frequently requiring intensive care. These observations could help prepare a new pandemic.
    MeSH term(s) Child ; Humans ; Infant ; Child, Preschool ; Adolescent ; Respiratory Syncytial Virus Infections/epidemiology ; Pandemics ; COVID-19/epidemiology ; Respiratory Syncytial Virus, Human ; Critical Care ; Respiratory Tract Infections
    Language English
    Publishing date 2023-12-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000004222
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    Zs.A 1852: Show issues Location:
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  10. Article: Delayed diagnosis of pneumonia in the emergency department: factors associated and prognosis.

    Bouam, Maria / Binquet, Christine / Moretto, Florian / Sixt, Thibault / Vourc'h, Michèle / Piroth, Lionel / Ray, Patrick / Blot, Mathieu

    Frontiers in medicine

    2023  Volume 10, Page(s) 1042704

    Abstract: Introduction: Whether a delayed diagnosis of community-acquired pneumonia (CAP) in the emergency department (ED) is associated with worse outcome is uncertain. We sought factors associated with a delayed diagnosis of CAP in the ED and those associated ... ...

    Abstract Introduction: Whether a delayed diagnosis of community-acquired pneumonia (CAP) in the emergency department (ED) is associated with worse outcome is uncertain. We sought factors associated with a delayed diagnosis of CAP in the ED and those associated with in-hospital mortality.
    Methods: Retrospective study including all inpatients admitted to an ED (Dijon University Hospital, France) from 1 January to 31 December 2019, and hospitalized with a diagnosis of CAP. Patients diagnosed with CAP in the ED (
    Results: 435 inpatients were included: 361 (83%) with an early and 74 (17%) with a delayed diagnosis. The latter less frequently required oxygen (54 vs. 77%;
    Conclusion: Delayed diagnosis of pneumonia was associated with a less severe clinical presentation, lack of obvious signs of pneumonia on chest X-ray, and delayed antibiotics initiation, but was not associated with worse outcome.
    Language English
    Publishing date 2023-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1042704
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