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  1. Article ; Online: Age-Related Changes in Total Corneal Astigmatism in Eyes With High Myopia.

    Hayashi, Ken / Uno, Koichi / Manabe, Shin-Ichi / Yoshimura, Koichi

    Cornea

    2023  

    Abstract: Purpose: The purpose of this study was to compare age-related changes in corneal astigmatism in eyes with and without high myopia.: Methods: Eight-hundred eyes with high myopia (axial length ≥26.0 mm) and 800 eyes without high myopia (200 eyes each ... ...

    Abstract Purpose: The purpose of this study was to compare age-related changes in corneal astigmatism in eyes with and without high myopia.
    Methods: Eight-hundred eyes with high myopia (axial length ≥26.0 mm) and 800 eyes without high myopia (200 eyes each from patients in their 40s, 50s, 60s, and ≥70s) underwent videokeratographic examination. The amounts of vertical/horizontal (Rx) and oblique astigmatism (Ry) components, irregular astigmatism, and corneal shape were compared between eyes with and without high myopia and among age categories.
    Results: In both groups, the mean Rx significantly changed to more positive with age (P < 0.001), whereas the Ry did not change significantly. The Rx was significantly more negative in the high myopia group than in the control group in all age categories (P ≤ 0.003), whereas the Ry did not differ significantly. The mean changes in the Rx and Ry during each 2 consecutive decades did not differ significantly between groups. The asymmetry and higher-order irregularity components increased with age (P ≤ 0.001) but did not differ significantly between groups, except for the higher-order irregularity in patients in their 60s (P = 0.018). In the averaged map, the corneal shape changed from with-the-rule to against-the-rule astigmatism with age in both groups, but the changes occurred later in the high myopia group.
    Conclusions: Age-related changes from with-the-rule to against-the-rule astigmatism occurred later in eyes with high myopia compared with eyes without high myopia in middle or older aged patients, but this change in each age decade was comparable between eyes with and without high myopia.
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000003447
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  2. Article: Ultrafiltration in Japanese critically ill patients with acute kidney injury on renal replacement therapy.

    Kitamura, Koichi / Hayashi, Koichi / Fujitani, Shigeki / Murugan, Raghavan / Suzuki, Toshihiko

    Journal of intensive care

    2021  Volume 9, Issue 1, Page(s) 77

    Abstract: A recent worldwide survey indicates an international diversity in net ultrafiltration ( ... ...

    Abstract A recent worldwide survey indicates an international diversity in net ultrafiltration (UF
    Language English
    Publishing date 2021-12-20
    Publishing country England
    Document type Letter
    ZDB-ID 2739853-5
    ISSN 2052-0492
    ISSN 2052-0492
    DOI 10.1186/s40560-021-00590-4
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  3. Article ; Online: Novel Mg

    Wang, Mengqi / Zhao, Yimeng / Hayashi, Yoshiki / Ito, Koichi / Hattori, Motoyuki

    Acta biochimica et biophysica Sinica

    2023  Volume 55, Issue 4, Page(s) 683–690

    Abstract: MgtE is a ... ...

    Abstract MgtE is a Mg
    MeSH term(s) Humans ; Antiporters/chemistry ; Antiporters/genetics ; Antiporters/metabolism ; Bacterial Proteins/metabolism ; Binding Sites ; Crystallography, X-Ray ; Models, Molecular ; X-Rays ; Thermus thermophilus
    Chemical Substances Antiporters ; Bacterial Proteins
    Language English
    Publishing date 2023-04-25
    Publishing country China
    Document type Journal Article
    ZDB-ID 2175256-4
    ISSN 1745-7270 ; 0582-9879 ; 1672-9145
    ISSN (online) 1745-7270
    ISSN 0582-9879 ; 1672-9145
    DOI 10.3724/abbs.2023067
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  4. Article ; Online: Polyarteritis nodosa with splenic rupture and multiple cerebral infarctions.

    Norimatsu, Yuta / Saku, Aiko / Kawashima, Hirotoshi / Minagawa, Takuya / Itano, Osamu / Shiga, Takashi / Hayashi, Yuichiro / Hirose, Koichi / Sugaya, Makoto

    The Journal of dermatology

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17162
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  5. Article ; Online: Intrathoracic Needle Migration from the Mediastinum into the Thoracic Cavity.

    Sato, Tomo / Kato, Yasufumi / Kataba, Hiroaki / Yoshida, Koichi / Hayashi, Hiroki / Kakihana, Masatoshi / Ikeda, Norihiko

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia

    2024  Volume 30, Issue 1

    Abstract: Intrathoracic needles are rarely used in clinical practice. They can migrate within the body, injure large blood vessels and other organs, and cause severe complications. We report an interesting case of intrathoracic needle removal using video-assisted ... ...

    Abstract Intrathoracic needles are rarely used in clinical practice. They can migrate within the body, injure large blood vessels and other organs, and cause severe complications. We report an interesting case of intrathoracic needle removal using video-assisted thoracoscopic surgery. The needle was inserted under the left clavicle, penetrated the mediastinum, and migrated into the right thoracic cavity. Although pneumothorax developed during the disease course, no severe complications were observed. This rare case illustrates the course of needle migration from the mediastinum into the thoracic cavity. Prompt imaging and surgical removal of foreign bodies are necessary in cases of intrathoracic foreign bodies.
    MeSH term(s) Humans ; Mediastinum ; Treatment Outcome ; Thoracic Cavity/surgery ; Foreign Bodies/surgery ; Thoracic Surgery, Video-Assisted/methods ; Foreign-Body Migration/surgery
    Language English
    Publishing date 2024-04-18
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2019756-1
    ISSN 2186-1005 ; 1341-1098
    ISSN (online) 2186-1005
    ISSN 1341-1098
    DOI 10.5761/atcs.cr.24-00039
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  6. Article ; Online: Efficacy of 3-day versus 5-day aprepitant regimens for long-delayed chemotherapy-induced nausea and vomiting in patients receiving cisplatin-based chemotherapy.

    Hayashi, Toshinobu / Shimokawa, Mototsugu / Matsuo, Koichi / Kawada, Kei / Nakano, Takafumi / Egawa, Takashi

    Expert opinion on pharmacotherapy

    2024  Volume 24, Issue 18, Page(s) 2221–2226

    Abstract: Background: Chemotherapy-induced nausea and vomiting (CINV) is an ongoing problem. While effectiveness of triplet antiemetic regimens in the delayed CINV phase (24-120 hours after administration of chemotherapy) has been studied, their effectiveness in ... ...

    Abstract Background: Chemotherapy-induced nausea and vomiting (CINV) is an ongoing problem. While effectiveness of triplet antiemetic regimens in the delayed CINV phase (24-120 hours after administration of chemotherapy) has been studied, their effectiveness in the long-delayed phase (120-168 hours post-administration) is unknown. We compared the efficacy of 3- and 5-day courses of a triplet antiemetic prophylaxis containing aprepitant (APR) in controlling long-delayed CINV after cisplatin (CDDP)-based chemotherapy.
    Research design and methods: We obtained patient-level data from a nationwide, multicenter, prospective observational study in Japan. The incidence and timing of CINV after 3- and 5-day APR-containing regimens were compared using inverse probability treatment weighting.
    Results: The analysis included 380 patients. The incidence rates of long-delayed nausea and vomiting were significantly reduced for the 5-day compared with the 3-day regimen (29.1% vs. 22.2%,
    Conclusion: A 5-day regimen triplet antiemetic prophylaxis with APR decreased long-delayed vomiting compared with a 3-day regimen in patients receiving CDDP-based chemotherapy. However, the 5-day regimen showed no advantage over the 3-day regimen against long-delayed nausea.
    MeSH term(s) Humans ; Antiemetics ; Antineoplastic Agents/adverse effects ; Aprepitant/therapeutic use ; Cisplatin/adverse effects ; Nausea/chemically induced ; Nausea/prevention & control ; Nausea/drug therapy ; Vomiting/chemically induced ; Vomiting/prevention & control ; Vomiting/drug therapy
    Chemical Substances Antiemetics ; Antineoplastic Agents ; Aprepitant (1NF15YR6UY) ; Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2023.2288288
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  7. Article ; Online: Statistical reliability of a relative standard deviation of chromatographic peak area estimated by a chemometric tool based on the FUMI theory.

    Kotani, Akira / Watanabe, Ryo / Hayashi, Yuzuru / Machida, Koichi / Hakamata, Hideki

    Journal of pharmaceutical and biomedical analysis

    2023  Volume 237, Page(s) 115777

    Abstract: In pharmaceutical analysis using a high-performance liquid chromatography (HPLC) system, repeatability assessment is significant to obtain reliable and precise quantitative results. The purpose of the present study is to experimentally show the ... ...

    Abstract In pharmaceutical analysis using a high-performance liquid chromatography (HPLC) system, repeatability assessment is significant to obtain reliable and precise quantitative results. The purpose of the present study is to experimentally show the statistical reliability of a relative standard deviation (RSD) of peak area estimated by a chemometric tool based on probability theory, called the function of mutual information (FUMI) theory, which stochastically provided an RSD of peak area and SD of baseline areas with width k (s(k)) from noises and a signal on a single chromatogram. An ultra-high-performance liquid chromatography with ultraviolet detection (UHPLC-UV) for determining ergosterol was applied as an example of the repeatability assessment. In addition, the statistical reliability of an RSD of peak area in the UHPLC-UV system was certified according to a chi-square (χ
    MeSH term(s) Reproducibility of Results ; Chemometrics ; Chromatography, High Pressure Liquid/methods
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 604917-5
    ISSN 1873-264X ; 0731-7085
    ISSN (online) 1873-264X
    ISSN 0731-7085
    DOI 10.1016/j.jpba.2023.115777
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  8. Article ; Online: Impact of dynamic parameter of trends in vital signs on the prediction of serious events in hospitalized patients -a retrospective observational study.

    Tanii, Rimi / Hayashi, Kuniyoshi / Naito, Takaki / Shui-Yee Wong, Zoie / Yoshida, Toru / Hayashi, Koichi / Fujitani, Shigeki

    Resuscitation plus

    2024  Volume 18, Page(s) 100628

    Abstract: Aim: Although early detection of patients' deterioration may improve outcomes, most of the detection criteria use on-the-spot values of vital signs. We investigated whether adding trend values over time enhanced the ability to predict adverse events ... ...

    Abstract Aim: Although early detection of patients' deterioration may improve outcomes, most of the detection criteria use on-the-spot values of vital signs. We investigated whether adding trend values over time enhanced the ability to predict adverse events among hospitalized patients.
    Methods: Patients who experienced adverse events, such as unexpected cardiac arrest or unplanned ICU admission were enrolled in this retrospective study. The association between the events and the combination of vital signs was evaluated at the time of the worst vital signs 0-8 hours before events (near the event) and at 24-48 hours before events (baseline). Multivariable logistic analysis was performed, and the area under the receiver operating characteristic curve (AUC) was used to assess the prediction power for adverse events among various combinations of vital sign parameters.
    Results: Among 24,509 in-patients, 54 patients experienced adverse events(cases) and 3,116 control patients eligible for data analysis were included. At the timepoint near the event, systolic blood pressure (SBP) was lower, heart rate (HR) and respiratory rate (RR) were higher in the case group, and this tendency was also observed at baseline. The AUC for event occurrence with reference to SBP, HR, and RR was lower when evaluated at baseline than at the timepoint near the event (0.85 [95%CI: 0.79-0.92] vs. 0.93 [0.88-0.97]). When the trend in RR was added to the formula constructed of baseline values of SBP, HR, and RR, the AUC increased to 0.92 [0.87-0.97].
    Conclusion: Trends in RR may enhance the accuracy of predicting adverse events in hospitalized patients.
    Language English
    Publishing date 2024-04-09
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-5204
    ISSN (online) 2666-5204
    DOI 10.1016/j.resplu.2024.100628
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  9. Article ; Online: Author Correction: Direct measurement of radiation exposure dose to individual organs during diagnostic computed tomography examination.

    Yamashita, Kazuta / Higashino, Kosaku / Hayashi, Hiroaki / Takegami, Kazuki / Hayashi, Fumio / Tsuruo, Yoshihiro / Sairyo, Koichi

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 5035

    Language English
    Publishing date 2022-03-23
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-08891-w
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  10. Article ; Online: Prevalence and characteristics of oblique astigmatism.

    Hayashi, Ken / Uno, Koichi / Manabe, Shin-Ichi / Hirata, Akira

    Eye (London, England)

    2023  Volume 37, Issue 15, Page(s) 3174–3179

    Abstract: Objective: To examine the incidence and characteristics of eyes with oblique astigmatism stratified by meridian, age, sex, and eye side (left to right).: Methods: One thousand eyes of 1000 patients with oblique corneal astigmatism underwent ... ...

    Abstract Objective: To examine the incidence and characteristics of eyes with oblique astigmatism stratified by meridian, age, sex, and eye side (left to right).
    Methods: One thousand eyes of 1000 patients with oblique corneal astigmatism underwent videokeratographic examination and was classified into 4 meridian categories: (1) 31°-45°, (2) 46°-59°, (3) 121°-135°, and (4) 136°-149°. Amounts of regular and irregular astigmatism, and the vertical/horizontal (Rx) and oblique astigmatism components (Ry) decomposed using vector analysis were compared among the 4 categories and age groups, and between sexes and eye sides.
    Results: Incidences of the 4 meridian categories were similar and did not differ significantly among age groups or between sexes. The incidence was significantly greater in eyes in meridian categories 1 and 2 in the left eye and categories 3 and 4 in the right eye, and significantly greater in men in their 40 s and 50 s and in women in their 70 s and 80 s (P < 0.0001). The mean regular astigmatism, asymmetry and higher-order irregularity components, and Rx and absolute Ry significantly increased with age (P ≤ 0.0372). The mean regular and irregular astigmatism, and absolute Rx and Ry did not differ significantly among the 4 categories, or between sexes or left and right eyes.
    Conclusions: The incidence of oblique astigmatism was significantly greater in the temporal side meridians, and the incidence in women increased with age. The degree of oblique astigmatism increased with age, with an increase in irregular astigmatism.
    MeSH term(s) Male ; Humans ; Female ; Astigmatism/etiology ; Prevalence ; Cornea ; Corneal Topography ; Corneal Diseases/complications
    Language English
    Publishing date 2023-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02470-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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