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  1. Article: Unveiling the Eris Subvariant: The Next Challenge in the COVID-19 Pandemic?

    Kali, Arunava

    Journal of Laboratory Physicians

    2023  

    Abstract: Since the COVID-19 pandemic's onset, the SARS-CoV-2 virus has displayed remarkable mutation abilities, resulting in distinct variants. Alpha, Beta, Gamma, Delta, and Omicron are major World Health Organization (WHO)-identified variants of concern. The ... ...

    Abstract Since the COVID-19 pandemic's onset, the SARS-CoV-2 virus has displayed remarkable mutation abilities, resulting in distinct variants. Alpha, Beta, Gamma, Delta, and Omicron are major World Health Organization (WHO)-identified variants of concern. The Omicron variant and its sub-lineages dominated globally in 2022. A novel strain, EG.5.1 (Eris), originating from Omicron's XBB sub-lineage, has recently sparked a significant COVID-19 surge across continents. Detected since June 2023, EG.5.1 is linked to increased cases in Europe, the Americas, and Asia. Factors like waning immunity, overcrowding, and poor air quality contributed to its rise. This variant is likely to prevail over other circulating variants and become dominant in UK by September 2023. Surveillance of its global epidemiology and implementing preventive measures have become imperative in light of the current situation.
    Keywords EG.5.1 ; Eris subvariant ; SARS-CoV-2
    Language English
    Publishing date 2023-09-08
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727 ; 0974-7826
    ISSN (online) 0974-7826
    ISSN 0974-2727 ; 0974-7826
    DOI 10.1055/s-0043-1774410
    Database Thieme publisher's database

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  2. Article ; Online: An Update on the Recent Diagnostic Modalities of SARS-CoV-2

    Marie Victor Pravin Charles / Arunava Kali / Santhanam Vidyalakshmi

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 3, Pp DE01-DE

    A Review

    2023  Volume 06

    Abstract: The pandemic of respiratory viral pneumonia initiated as an outbreak during December 2019, at the Hubei region, China. The demanding research work conducted by the scientific community across the globe identified the causative agent as Severe Acute ... ...

    Abstract The pandemic of respiratory viral pneumonia initiated as an outbreak during December 2019, at the Hubei region, China. The demanding research work conducted by the scientific community across the globe identified the causative agent as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The Case Fatality Rate (CFR) is high for the infection. Laboratory diagnosis of infectious diseases has an integral role in case surveillance, diagnosis, treatment, and prevention. SARS-CoV-2 is a positive sense single stranded Ribonucleic Acid (RNA) virus grouped under the order nidovirales, Family Coronaviridae, and subfamily Orthocoronavirinae. The structural proteins are spike protein (S), membrane protein (M), nucleocapsid protein (N), and the envelope protein (E). The common symptoms are fever, cough, dyspnoea, fatigue, headache, muscle pain, anosmia, and ageusia. The less common symptoms are sore throat, congestion, nausea, vomiting and diarrhoea. Sample collection is a critical step in the laboratory diagnosis of SARS-CoV-2 infection. The molecular methods used for diagnosis of SARS-CoV-2 are Real time Reverse Transcription Polymerase Chain Reaction (r-RT-PCR), Reverse Transcription Loop Mediated Isothermal Amplification (RT-LAMP), digital PCR, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) based assay and sequencing methods. The antigen and antibody detection methods supplement the molecular tests. Although a huge array of tests are available, the pertinent choice of diagnostic test is crucial. The molecular detection methods are highly sensitive, accurate and reliable.
    Keywords covid-19 diagnostic testing ; covid-19 nucleic acid testing ; sars-cov-2 infection serological testing ; Medicine ; R
    Subject code 572 ; 570
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Impact of Monsoon on the Pattern of Infectious Diseases in the Indian Setting-A Review

    Marie Victor Pravin Charles / Arunava Kali / Santhanam Vidyalakshmi

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 4, Pp DE01-DE

    2023  Volume 05

    Abstract: The survival of life on earth depends on equilibrium between the organisms and the environment. The monsoon is a seasonal variation prevailing in the Indian sub-continent. Monsoon has two seasons which are separated by a transition. The infectious ... ...

    Abstract The survival of life on earth depends on equilibrium between the organisms and the environment. The monsoon is a seasonal variation prevailing in the Indian sub-continent. Monsoon has two seasons which are separated by a transition. The infectious diseases epidemiology is affected by both climatic and societal influences. An interaction of climatic and societal influence favours the infectious disease exposure in a population. The infectious diseases affecting the population can be broadly classified as vector borne diseases, food borne diseases, water borne diseases, and respiratory diseases. The rainfall associated change in temperature and floods favours the survival of infectious diseases and their transmitting vectors. The changing global climatic trends including the EL nino Southern oscillation bring undue rainfall during other seasons. The drastic events associated with these climatic changes affect the heath and sanitation infrastructure. India being a developing country has more vulnerability to such infections. A better strengthening of the infrastructure and health policies is the need of the hour to curb the infections.
    Keywords climate change ; elevated temperature ; environment ; food borne disease ; infectious agents ; rainy season ; vector borne disease ; water borne disease ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Teixobactin: a novel antibiotic in treatment of gram positive bacterial infections.

    Kali, Arunava

    Journal of clinical and diagnostic research : JCDR

    2015  Volume 9, Issue 3, Page(s) DL01

    Language English
    Publishing date 2015-03-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2775283-5
    ISSN 0973-709X ; 2249-782X
    ISSN (online) 0973-709X
    ISSN 2249-782X
    DOI 10.7860/JCDR/2015/13033.5720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Scientific impact and altmetrics.

    Kali, Arunava

    Indian journal of pharmacology

    2015  Volume 47, Issue 5, Page(s) 570–571

    MeSH term(s) Humans ; Journal Impact Factor ; Periodicals as Topic ; Publishing ; Research
    Language English
    Publishing date 2015-09
    Publishing country India
    Document type Letter
    ZDB-ID 605829-2
    ISSN 1998-3751 ; 0253-7613
    ISSN (online) 1998-3751
    ISSN 0253-7613
    DOI 10.4103/0253-7613.165184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1983: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 311: Show issues

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  6. Article ; Online: Rapid characterization of carbapenem-resistant Enterobacterales by multiplex lateral flow assay and detection of ceftazidime-avibactam-aztreonam synergy.

    Kalaivani, R / Kali, Arunava / Surendran, R / Sujaritha, T / Ganesh Babu, C P

    Indian journal of medical microbiology

    2024  Volume 47, Page(s) 100530

    Abstract: Purpose: The choice of antibiotics for treatment of Carbapenem-Resistant Enterobacterales (CRE) is increasing becoming limited due to co-expression of Metallo-beta-lactamases (MBL) along with other carbapenemases in these isolates. The study aimed to ... ...

    Abstract Purpose: The choice of antibiotics for treatment of Carbapenem-Resistant Enterobacterales (CRE) is increasing becoming limited due to co-expression of Metallo-beta-lactamases (MBL) along with other carbapenemases in these isolates. The study aimed to investigate the occurrence of CRE and to determine the in-vitro synergy and clinical outcomes of Ceftazidime-Avibactam and Aztreonam combination in CRE infections in adult Intensive Care Units (ICUs).
    Methods: 79 CRE isolates recovered from adult ICUs during January to March 2023 were tested by O.K.N.V.I. RESIST-5, a lateral flow multiplex assay for rapid detection of OXA-48-like, NDM, IMP, VIM, and KPC carbapenemases. Ceftazidime-Avibactam MIC was determined by microbroth dilution method and in vitro synergy between Ceftazidime-Avibactam and Aztreonam was assessed by Modified E-test/disc diffusion method for these isolates.
    Results: The study revealed 7.5 % occurrence of CRE in our hospital, with high occurrence of NDM (n = 42, 53.1 %) and OXA-48-like (n = 63, 79.7 %) carbapenemase. Production of more than one type of carbapenemases was found in 44 isolates. A total of 57 isolates (72 %) had Ceftazidime-Avibactam resistance and 44 of them displayed Ceftazidime-Avibactam and Aztreonam in-vitro synergy. Successful clinical outcome was observed in two patients who received Ceftazidime-Avibactam and Aztreonam combination therapy for 7 days or more.
    Conclusions: Despite the preponderance of Ceftazidime-Avibactam resistant CRE expressing NDM and OXA-48-like carbapenemase in our hospital, 77.2 % of them displayed in-vitro synergy of Ceftazidime-Avibactam with Aztreonam. It emphasizes the potential therapeutic utility of this combination in CRE strains showing coproduction of MBL and serine carbapenemases. Greater therapeutic potential of Ceftazidime-Avibactam and Aztreonam combination was observed with extended duration of therapy. However, further clinical evidence is needed to establish the efficacy of this combination and consider other factors that influence treatment outcomes.
    MeSH term(s) Adult ; Humans ; Aztreonam/pharmacology ; Aztreonam/therapeutic use ; Ceftazidime/pharmacology ; Ceftazidime/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Drug Combinations ; beta-Lactamases ; Carbapenems ; Microbial Sensitivity Tests ; Azabicyclo Compounds
    Chemical Substances Aztreonam (G2B4VE5GH8) ; avibactam, ceftazidime drug combination ; Ceftazidime (9M416Z9QNR) ; Anti-Bacterial Agents ; Drug Combinations ; beta-Lactamases (EC 3.5.2.6) ; Carbapenems ; Azabicyclo Compounds
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2024.100530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2639: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Reference management

    Arunava Kali

    Journal of Advanced Pharmaceutical Technology & Research, Vol 7, Iss 1, Pp 27-

    A critical element of scientific writing

    2016  Volume 29

    Abstract: With the rapid growth of medical science, the number of scientific writing contributing to medical literature has increased significantly in recent years. Owing to considerable variation of formatting in different citation styles, strict adherence to the ...

    Abstract With the rapid growth of medical science, the number of scientific writing contributing to medical literature has increased significantly in recent years. Owing to considerable variation of formatting in different citation styles, strict adherence to the accurate referencing manually is labor intensive and challenging. However, the introduction of referencing tools has decreased the complexity to a great extent. These software have advanced overtime to include newer features to support effective reference management. Since scientific writing is an essential component of medical curriculum, it is imperative for medical graduates to understand various referencing systems to effectively make use of these tools in their dissertations and future researches.
    Keywords Citation manager ; reference management ; referencing tools ; Medicine ; R ; Pharmacy and materia medica ; RS1-441
    Publishing date 2016-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Psychobiotics

    Arunava Kali

    Biomedical Journal, Vol 39, Iss 3, Pp 223-

    An emerging probiotic in psychiatric practice

    2016  Volume 224

    Abstract: Intestinal microbial flora plays critical role in maintenance of health. Probiotic organisms have been recognized as an essential therapeutic component in the treatment of intestinal dysbiosis. Current research suggests their health benefits extends ... ...

    Abstract Intestinal microbial flora plays critical role in maintenance of health. Probiotic organisms have been recognized as an essential therapeutic component in the treatment of intestinal dysbiosis. Current research suggests their health benefits extends beyond intestinal disorders. The neuroactive molecules produced by the gut microbiota has been found to modulate neural signals which affect neurological and psychiatric parameters like sleep, appetite, mood and cognition. Use of these novel probiotics opens up the possibility of restructuring of intestinal microbiota for effective management of various psychiatric disorders.
    Keywords Psychobiotics ; Microbiome ; Intestinal microbiota ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2016-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Microbial infection imaging: A novel diagnostic approach.

    Kali, Arunava

    Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

    2015  Volume 30, Issue 2, Page(s) 189–190

    Language English
    Publishing date 2015-01-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 2181722-4
    ISSN 0974-0244 ; 0972-3919
    ISSN (online) 0974-0244
    ISSN 0972-3919
    DOI 10.4103/0972-3919.152993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Scientific impact and altmetrics

    Arunava Kali

    Indian Journal of Pharmacology, Vol 47, Iss 5, Pp 570-

    2015  Volume 571

    Keywords Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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