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  1. Article ; Online: Remembering Jeff Robbins: The Father of Cardiac Transgenesis.

    Molkentin, Jeffery D / Leinwand, Leslie A

    JACC. Basic to translational science

    2022  Volume 7, Issue 10, Page(s) 1063–1065

    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Editorial
    ISSN 2452-302X
    ISSN (online) 2452-302X
    DOI 10.1016/j.jacbts.2022.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: At the Brink of Human Therapy to Generate New Myocytes in the Adult Injured Heart.

    Prasad, Vikram / Molkentin, Jeffery D

    Circulation

    2022  Volume 145, Issue 17, Page(s) 1356–1358

    MeSH term(s) Heart ; Humans ; Muscle Cells
    Language English
    Publishing date 2022-04-25
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.122.059106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Resident macrophages keep mitochondria running in the heart.

    Vagnozzi, Ronald J / Molkentin, Jeffery D

    Cell research

    2020  Volume 30, Issue 12, Page(s) 1057–1058

    MeSH term(s) Heart ; Homeostasis ; Macrophages/metabolism ; Mitochondria ; Running
    Language English
    Publishing date 2020-09-22
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1319303-x
    ISSN 1748-7838 ; 1001-0602
    ISSN (online) 1748-7838
    ISSN 1001-0602
    DOI 10.1038/s41422-020-00427-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 5283: Show issues Location:
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  4. Article ; Online: MCU-independent Ca

    Bround, Michael J / Abay, Eaman / Huo, Jiuzhou / Havens, Julian R / York, Allen J / Bers, Donald M / Molkentin, Jeffery D

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6751

    Abstract: Mitochondrial ... ...

    Abstract Mitochondrial Ca
    MeSH term(s) Animals ; Humans ; Mice ; Calcium/metabolism ; Calcium Channels/metabolism ; Cell Death ; Mitochondria/metabolism ; Mitochondrial Membrane Transport Proteins/metabolism ; Muscular Dystrophy, Duchenne/pathology ; Necrosis/metabolism
    Chemical Substances Calcium (SY7Q814VUP) ; Calcium Channels ; Mitochondrial Membrane Transport Proteins ; Mcu protein, mouse
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57340-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Undeniable Evidence That the Adult Mammalian Heart Lacks an Endogenous Regenerative Stem Cell.

    Maliken, Bryan D / Molkentin, Jeffery D

    Circulation

    2018  Volume 138, Issue 8, Page(s) 806–808

    MeSH term(s) Animals ; Cell Lineage ; Heart ; Recombinases ; Stem Cells ; Mice
    Chemical Substances Recombinases
    Language English
    Publishing date 2018-12-22
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.118.035186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion.

    Vagnozzi, Ronald J / Sargent, Michelle A / Molkentin, Jeffery D

    Circulation

    2020  Volume 141, Issue 12, Page(s) 1037–1039

    MeSH term(s) Animals ; Cell- and Tissue-Based Therapy/methods ; Disease Models, Animal ; Injections ; Myocytes, Cardiac/pathology ; Rodentia
    Language English
    Publishing date 2020-03-23
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.119.044686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cardiac Cell Therapy Fails to Rejuvenate the Chronically Scarred Rodent Heart.

    Vagnozzi, Ronald J / Kasam, Rajesh K / Sargent, Michelle A / Molkentin, Jeffery D

    Circulation

    2021  Volume 144, Issue 4, Page(s) 328–331

    MeSH term(s) Animals ; Bone Marrow Cells ; Bone Marrow Transplantation ; Cardiomyopathy, Restrictive/diagnosis ; Cardiomyopathy, Restrictive/etiology ; Cardiomyopathy, Restrictive/therapy ; Cell- and Tissue-Based Therapy/methods ; Chronic Disease ; Disease Models, Animal ; Female ; Fibrosis ; Ischemia/complications ; Male ; Mice ; Rodentia ; Stem Cell Transplantation ; Treatment Failure ; Treatment Outcome
    Language English
    Publishing date 2021-07-26
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.053080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy.

    Bround, Michael J / Havens, Julian R / York, Allen J / Sargent, Michelle A / Karch, Jason / Molkentin, Jeffery D

    Science advances

    2023  Volume 9, Issue 34, Page(s) eadi2767

    Abstract: ... an unknown component that requires the chaperone cyclophilin D (CypD) to activate. This model was examined ...

    Abstract Mitochondrial permeability transition pore (MPTP) formation contributes to ischemia-reperfusion injury in the heart and several degenerative diseases, including muscular dystrophy (MD). MD is a family of genetic disorders characterized by progressive muscle necrosis and premature death. It has been proposed that the MPTP has two molecular components, the adenine nucleotide translocase (ANT) family of proteins and an unknown component that requires the chaperone cyclophilin D (CypD) to activate. This model was examined in vivo by deleting the gene encoding ANT1 (
    MeSH term(s) Animals ; Mice ; Muscular Dystrophies ; Necrosis ; Cell Death ; Peptidyl-Prolyl Isomerase F ; Disease Models, Animal
    Chemical Substances Peptidyl-Prolyl Isomerase F
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adi2767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.

    Kuwabara, Yasuhide / York, Allen J / Lin, Suh-Chin / Sargent, Michelle A / Grimes, Kelly M / Pirruccello, James P / Molkentin, Jeffery D

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 19, Page(s) e2213696120

    Abstract: To better understand the genetic basis of heart disease, we identified a variant in ... ...

    Abstract To better understand the genetic basis of heart disease, we identified a variant in the
    MeSH term(s) Humans ; Animals ; Mice ; Actins/metabolism ; Sarcomeres/metabolism ; Genome-Wide Association Study ; Actin Cytoskeleton/metabolism ; Cardiomyopathies/metabolism ; Mammals/genetics ; Microfilament Proteins/metabolism ; Trans-Activators/metabolism ; Tropomodulin/metabolism ; Cytoskeletal Proteins/metabolism ; Muscle Proteins/metabolism
    Chemical Substances Actins ; FLII protein, human ; Microfilament Proteins ; Trans-Activators ; TMOD1 protein, human ; Tropomodulin ; leiomodin protein, mouse ; Cytoskeletal Proteins ; Muscle Proteins ; FlII protein, mouse
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2213696120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1148: Show issues Location:
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  10. Article ; Online: Letter by Molkentin regarding article, "The absence of evidence is not evidence of absence: the pitfalls of Cre Knock-Ins in the c-Kit Locus".

    Molkentin, Jeffery D

    Circulation research

    2014  Volume 115, Issue 8, Page(s) e21–3

    MeSH term(s) Animals ; Gene Knock-In Techniques ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Integrases/genetics ; Integrases/metabolism ; Mice ; Mice, Transgenic ; Myoblasts, Cardiac/cytology ; Myoblasts, Cardiac/metabolism ; Myocardium/cytology ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Proto-Oncogene Proteins c-kit/genetics ; Proto-Oncogene Proteins c-kit/metabolism
    Chemical Substances Green Fluorescent Proteins (147336-22-9) ; Proto-Oncogene Proteins c-kit (EC 2.7.10.1) ; Cre recombinase (EC 2.7.7.-) ; Integrases (EC 2.7.7.-)
    Language English
    Publishing date 2014-09-25
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.114.305011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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