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  1. Book ; Online: Solid Organ Transplantation in the Era of COVID-19

    Schuurmans, Macé M / Hage, René / Hage, René

    2023  

    Keywords Research & information: general ; Biology, life sciences ; SARS-CoV-2 ; coronavirus ; immunosuppression ; tacrolimus ; corticosteroids ; mycophenolate mofetil ; hyperinflammation ; cytokine storm ; pandemic ; transplantation ; Lung Transplantation ; COVID-19 ; Coronavirus ; norovirus ; treatment ; hypothesis ; cytokine storm syndrome ; FK506 ; cyclosporine ; myocarditis ; pediatric heart transplantation ; viral infection ; dexamethasone ; remdesivir ; hemodialysis ; transplant ; kidney ; PCR ; infection ; transplant recipients ; inflammation ; survival ; n/a ; solid-organ transplant ; unvaccinated ; lung transplantation ; fibrosis ; phenotype hypothesis ; lung transplant recipients ; immunocompromised ; breakthrough infections ; chronic lung allograft dysfunction ; community-acquired respiratory viral infection ; CLAD hypothesis
    Language English
    Size 1 electronic resource (128 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030722349
    ISBN 9783036565149 ; 3036565140
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Calcineurin Inhibitors and COVID-19.

    Hage, René / Schuurmans, Macé M

    Reumatologia clinica

    2022  Volume 18, Issue 5, Page(s) 314–315

    MeSH term(s) COVID-19 ; Calcineurin Inhibitors/pharmacology ; Calcineurin Inhibitors/therapeutic use ; Humans ; Immunosuppressive Agents/adverse effects
    Chemical Substances Calcineurin Inhibitors ; Immunosuppressive Agents
    Language English
    Publishing date 2022-05-13
    Publishing country Spain
    Document type Letter ; Comment
    ISSN 2173-5743
    ISSN (online) 2173-5743
    DOI 10.1016/j.reumae.2020.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Malaria-associated pulmonary edema

    Rene Hage / Macé M Schuurmans

    Eurasian Journal of Pulmonology, Vol 22, Iss 2, Pp 132-

    2020  Volume 134

    Abstract: Malaria-associated (MA) noncardiogenic pulmonary edema, or its more severe forms, i.e. acute lung injury and acute respiratory distress syndrome due to Plasmodium malariae, is a potentially fatal complication of malaria. It can mimic respiratory ... ...

    Abstract Malaria-associated (MA) noncardiogenic pulmonary edema, or its more severe forms, i.e. acute lung injury and acute respiratory distress syndrome due to Plasmodium malariae, is a potentially fatal complication of malaria. It can mimic respiratory infections and present with concurrent malarial pulmonary edema and bacteriological respiratory infection. In our patient, malaria was diagnosed by microscopy (peripheral thick and thin Giemsa-stained blood smear) and serology testing. The chest computed tomography showed interstitial edema and a pleural effusion. Bronchoalveolar lavage was performed, which was negative for both bacteria and hemozoin. After initiation of antimalarial treatment, the patient rapidly responded. Recognizing and promptly treating malaria is critical to reduce the mortality of MA pulmonary complications.
    Keywords acute respiratory distress syndrome ; hemozoin ; malaria ; plasmodium malariae ; pleural effusion ; pulmonary edema ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article ; Online: Adaptive Immunosuppression in Lung Transplant Recipients Applying Complementary Biomarkers: The Zurich Protocol.

    Schuurmans, Macé M / Raeber, Miro E / Roeder, Maurice / Hage, René

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 3

    Abstract: Achieving adequate immunosuppression for lung transplant recipients in the first year after lung transplantation is a key challenge. Prophylaxis of allograft rejection must be balanced with the adverse events associated with immunosuppressive drugs, for ... ...

    Abstract Achieving adequate immunosuppression for lung transplant recipients in the first year after lung transplantation is a key challenge. Prophylaxis of allograft rejection must be balanced with the adverse events associated with immunosuppressive drugs, for example infection, renal failure, and diabetes. A triple immunosuppressive combination is standard, including a steroid, a calcineurin inhibitor, and an antiproliferative compound beginning with the highest levels of immunosuppression and a subsequent tapering of the dose, usually guided by therapeutic drug monitoring and considering clinical results, bronchoscopy sampling results, and additional biomarkers such as serum viral replication or donor-specific antibodies. Balancing the net immunosuppression level required to prevent rejection without overly increasing the risk of infection and other complications during the tapering phase is not well standardized and requires repeated assessments for dose-adjustments. In our adaptive immunosuppression approach, we additionally consider results from the white blood cell counts, in particular lymphocytes and eosinophils, as biomarkers for monitoring the level of immunosuppression and additionally use them as therapeutic targets to fine-tune the immunosuppressive strategy over time. The concept and its rationale are outlined, and areas of future research mentioned.
    MeSH term(s) Humans ; Transplant Recipients ; Immunosuppressive Agents/adverse effects ; Immunosuppression Therapy/adverse effects ; Biomarkers ; Lung ; Graft Rejection/prevention & control
    Chemical Substances Immunosuppressive Agents ; Biomarkers
    Language English
    Publishing date 2023-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59030488
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Cyclosporine A and COVID-19 – The COQUIMA cohort

    Macé M. Schuurmans / René Hage

    EClinicalMedicine, Vol 31, Iss , Pp 100680- (2021)

    2021  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Suggested management of e-cigarette or vaping product use associated lung injury (EVALI).

    Hage, René / Schuurmans, Macé M

    Journal of thoracic disease

    2020  Volume 12, Issue 7, Page(s) 3460–3468

    Language English
    Publishing date 2020-07-31
    Publishing country China
    Document type Editorial
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2020.03.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cyclosporine A and COVID-19 - The COQUIMA cohort.

    Schuurmans, Macé M / Hage, René

    EClinicalMedicine

    2020  Volume 31, Page(s) 100680

    Language English
    Publishing date 2020-12-23
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2020.100680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Calcineurin Inhibitors and COVID-19.

    Hage, René / Schuurmans, Macé M

    Reumatologia clinica

    2020  

    Keywords covid19
    Language Spanish
    Publishing date 2020-09-24
    Publishing country Spain
    Document type Letter
    ISSN 2173-5743
    ISSN (online) 2173-5743
    DOI 10.1016/j.reuma.2020.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Coronavirus Disease 2019 (COVID-19) in Solid-organ Transplant Recipients.

    Hage, René / Schuurmans, Macé M

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 73, Issue 9, Page(s) e2832–e2833

    MeSH term(s) COVID-19 ; Humans ; Organ Transplantation/adverse effects ; SARS-CoV-2 ; Transplant Recipients
    Keywords covid19
    Language English
    Publishing date 2020-10-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa1629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

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  10. Article: Vaping-assoziierte Lungenerkrankung «VAPI».

    Hage, René / Schuurmans, Macé M

    Praxis

    2020  Volume 109, Issue 13, Page(s) 1063–1069

    Abstract: Vaping-Associated Pulmonary ... ...

    Title translation Vaping-Associated Pulmonary Illness.
    Abstract Vaping-Associated Pulmonary Illness
    MeSH term(s) Electronic Nicotine Delivery Systems ; Humans ; Lung ; Lung Diseases/etiology ; Vaping/adverse effects
    Language German
    Publishing date 2020-10-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 1661-8157 ; 0369-8394
    ISSN (online) 1661-8165
    ISSN 1661-8157 ; 0369-8394
    DOI 10.1024/1661-8157/a003529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.118: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 12: Show issues

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