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  1. Article ; Online: Chemical Bonding, 10Dq Parameter and Superexchange in the Model Compound KNiF3.

    Sánchez-Movellán, Inés / Aramburu, Jose Antonio / Moreno, Miguel

    Chemphyschem : a European journal of chemical physics and physical chemistry

    2024  , Page(s) e202400006

    Abstract: The cubic field splitting parameter, 10Dq, plays a central role in the ligand field theory on insulating transition metal compounds. Experimental data prove that 10Dq depends on changes of the metal-ligand distance, R. Despite this fact has consequences ... ...

    Abstract The cubic field splitting parameter, 10Dq, plays a central role in the ligand field theory on insulating transition metal compounds. Experimental data prove that 10Dq depends on changes of the metal-ligand distance, R. Despite this fact has consequences on optical and magnetic properties of such compounds, its actual origin is still controversial. Seeking to clarify that crucial issue, this work is focused on KNiF3, a reference system among insulating transition metal compounds. By means of first principles calculations we show that, the R-dependence of 10Dq does not arise neither from the crystal field contribution nor from the covalent admixture of 3d(Ni) with valence 2p(F) orbitals. Indeed, we prove that it is mainly due to the covalency with 2s(F) orbitals, highly sensitive to R variations. The calculations show that the 3d-2pσ and 3d-2pπ admixtures raise practically equal the energy of antibonding eg and t2g orbitals of NiF64- units in KNiF3 thus leading to a null contribution to 10Dq. This conclusion is not significantly altered when considering the excited state 3T2(t2g5eg3). The different influence of chemical bonding on the superexchange constant, J, and 10Dq is also discussed in a second step. The meaning of 10Dq is also briefly analyzed.
    Language English
    Publishing date 2024-04-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2025223-7
    ISSN 1439-7641 ; 1439-4235
    ISSN (online) 1439-7641
    ISSN 1439-4235
    DOI 10.1002/cphc.202400006
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  2. Article: Treatment of Chondral Lesions in the Knee.

    Filho, José Paulo Aramburu Gabbi / Sousa, Eduardo Branco de

    Revista brasileira de ortopedia

    2023  Volume 58, Issue 4, Page(s) e551–e556

    Abstract: Articular cartilage injuries are common and lead to early joint deterioration and osteoarthritis. Articular cartilage repair techniques aim at forming a cartilaginous neo-tissue to support the articular load and prevent progressive degeneration. Several ... ...

    Abstract Articular cartilage injuries are common and lead to early joint deterioration and osteoarthritis. Articular cartilage repair techniques aim at forming a cartilaginous neo-tissue to support the articular load and prevent progressive degeneration. Several techniques are available for this purpose, such as microfracture and chondrocyte transplantation. However, the procedural outcome is often fibrocartilage, which does not have the same mechanical resistance as cartilaginous tissue. Procedures with autologous osteochondral graft have a morbidity risk, and tissue availability limits their use. As such, larger lesions undergo osteochondral transplantation using fresh or frozen grafts. New techniques using minced or particulate cartilage fragments or mesenchymal stem cells are promising. This paper aims to update the procedures for treating chondral lesions of the knee.
    Language English
    Publishing date 2023-08-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2411301-3
    ISSN 1982-4378 ; 0102-3616
    ISSN (online) 1982-4378
    ISSN 0102-3616
    DOI 10.1055/s-0043-1772196
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  3. Article ; Online: Understanding of Flow Allows Better Tumor Microsphere Coverage.

    Aramburu, Jorge / Antón, Raúl / Rodríguez-Fraile, Macarena / Bilbao, José I

    Journal of vascular and interventional radiology : JVIR

    2022  Volume 34, Issue 1, Page(s) 21–22

    MeSH term(s) Humans ; Microspheres ; Neoplasms ; Regional Blood Flow
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2022.09.009
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3720: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Understanding the Structure and Ground State of the Prototype CuF

    Aramburu, José Antonio / Moreno, Miguel

    Inorganic chemistry

    2019  Volume 58, Issue 7, Page(s) 4609–4618

    Abstract: Insulating ... ...

    Abstract Insulating CuF
    Language English
    Publishing date 2019-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.9b00178
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  5. Article: Functional paraganglioma, an uncommon cause of seminoma metastasis, diagnostic and therapeutic management.

    García Picazo, Alberto / Sáez, José / Aramburu, Alba / Centeno, Xavier / Romagosa, Cleofé / Díez-Caballero Alonso, Alberto

    Revista espanola de enfermedades digestivas

    2024  

    Abstract: We report a 62-year-old male, with history of uncontrolled hypertension (3 drugs) in who, it was found an incidentally left retroperitoneal hypervascular tumor (5.7 x 3.5 cm) in the CT. It was demonstrated contact between tumor and left renal artery and ... ...

    Abstract We report a 62-year-old male, with history of uncontrolled hypertension (3 drugs) in who, it was found an incidentally left retroperitoneal hypervascular tumor (5.7 x 3.5 cm) in the CT. It was demonstrated contact between tumor and left renal artery and ureter, without regional lymphadenopathy. The patient was asymptomatic, but had increased of norepinephrine (1141.1 pg/mL), epinephrine (93.3 pg/mL) and serotonin blood levels (264.1 g/L). The MRI confirm the tumor, with serotonin affinity in the 68Galium-Edotreotide PET/CT (DOTATATE) but not in the MIBG/Scan. Therefore, a paraganglioma was the suspected diagnosis. Tumor board recommended excision, due to the risk of being a functional paraganglioma. The tumor was resected through laparoscopic approach after alpha-beta-adrenergic blockade. Postoperatively, hypertension and norepinephrine blood levels were normalized. The histological report surprisingly showed a Seminoma (positivity for PLAP, OCT ¾, c-kit, MDM2) and the surgical margins were free.
    Language English
    Publishing date 2024-01-29
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2024.10232/2023
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 199: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Influence of physical activity on the prognosis of COPD patients: the HADO.2 score - health, activity, dyspnoea and obstruction.

    Esteban, Cristóbal / Aguirre, Nere / Aramburu, Amaia / Moraza, Javier / Chasco, Leyre / Aburto, Myriam / Aizpiri, Susana / Golpe, Rafael / Quintana, José M

    ERJ open research

    2024  Volume 10, Issue 1

    Abstract: Objective: The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score).! ...

    Abstract Objective: The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score).
    Methods: A prospective, observational, non-intervention study was carried out. Patients were recruited from the six outpatient clinics of the respiratory service of a single university hospital. The component variables of the HADO.2 score and BODE index were studied, and PA was measured using an accelerometer. The outcomes for the HADO.2 score were mortality and hospitalisations during follow-up and an exploration of the correlation with health-related quality of life at the moment of inclusion in the study.
    Results: 401 patients were included in the study and followed up for three years. The HADO.2 score showed good predictive capacity for mortality: C-index 0.79 (0.72-0.85). The C-index for hospitalisations was 0.72 (0.66-0.77) and the predictive ability for quality of life, as measured by R2, was 0.63 and 0.53 respectively for the Saint George's Respiratory Questionnaire and COPD Assessment Test.
    Conclusions: There was no statistically significant difference between the mortality predictive capacity of the HADO.2 score and the BODE index. Adding PA to the original BODE index significantly improved the predictive capacity of the index. The HADO.2 score, which includes PA as a key variable, showed good predictive capacity for mortality and hospitalisations. There were no differences in the predictive capacity of the HADO.2 score and the BODE index.
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00488-2023
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  7. Article ; Online: Ground State and Optical Excitations in Compounds with Tetragonal CuF

    Aramburu, Jose Antonio / Moreno, Miguel

    Inorganic chemistry

    2019  Volume 59, Issue 1, Page(s) 539–547

    Abstract: It has been argued that ... ...

    Abstract It has been argued that AAlCuF
    Language English
    Publishing date 2019-12-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.9b02827
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  8. Article ; Online: Regulation of Inflammatory Functions of Macrophages and T Lymphocytes by NFAT5.

    Aramburu, Jose / López-Rodríguez, Cristina

    Frontiers in immunology

    2019  Volume 10, Page(s) 535

    Abstract: The transcription factor NFAT5, also known as TonEBP, belongs to the family of Rel homology domain-containing factors, which comprises the NF-κB proteins and the calcineurin-dependent NFAT1 to NFAT4. NFAT5 shares several structural and functional ... ...

    Abstract The transcription factor NFAT5, also known as TonEBP, belongs to the family of Rel homology domain-containing factors, which comprises the NF-κB proteins and the calcineurin-dependent NFAT1 to NFAT4. NFAT5 shares several structural and functional features with other Rel-family factors, for instance it recognizes DNA elements with the same core sequence as those bound by NFAT1 to 4, and like NF-κB it responds to Toll-like receptors (TLR) and activates macrophage responses to microbial products. On the other hand, NFAT5 is quite unique among Rel-family factors as it can be activated by hyperosmotic stress caused by elevated concentrations of extracellular sodium ions. NFAT5 regulates specific genes but also others that are inducible by NF-κB and NFAT1 to 4. The ability of NFAT5 to do so in response to hypertonicity, microbial products, and inflammatory stimuli may extend the capabilities of immune cells to mount effective anti-pathogen responses in diverse microenvironment and signaling conditions. Recent studies identifying osmostress-dependent and -independent functions of NFAT5 have broadened our understanding of how NFAT5 may modulate immune function. In this review we focus on the role of NFAT5 in macrophages and T cells in different contexts, discussing findings from
    MeSH term(s) Animals ; Humans ; Hypernatremia/immunology ; Macrophages/immunology ; Osmotic Pressure ; T-Lymphocytes/immunology ; Transcription Factors/immunology
    Chemical Substances NFAT5 protein, human ; Nfat5 protein, mouse ; Transcription Factors
    Language English
    Publishing date 2019-03-20
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2019.00535
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  9. Article ; Online: Social Media Multidimensional Analysis for Intelligent Health Surveillance.

    Aramburu, María José / Berlanga, Rafael / Lanza, Indira

    International journal of environmental research and public health

    2020  Volume 17, Issue 7

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Data Mining ; Public Health Surveillance ; Social Media ; Social Networking
    Language English
    Publishing date 2020-03-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17072289
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  10. Article ; Online: Daniel Alcides Carrión

    José Alejandro Graña Aramburú

    Acta Médica Peruana, Vol 32, Iss

    una visión funcional

    2016  Volume 3

    Abstract: Se hace la consideración de Daniel Alcides Carrión, héroe de la Medicina peruana y de la Nación, desde el punto de vista fenomenológico, tanto filosófico como psicológico, considerando más la visión social que un fenómeno individual, bajo las influencias ...

    Abstract Se hace la consideración de Daniel Alcides Carrión, héroe de la Medicina peruana y de la Nación, desde el punto de vista fenomenológico, tanto filosófico como psicológico, considerando más la visión social que un fenómeno individual, bajo las influencias de las corrientes de pensamiento vigentes a fines del siglo XIX. Tanto el romanticismo como el positivismo fueron de origen europeo, pero influenciaron definitivamente en el Perú en la época de Carrión y, seguramente, tuvieron que ver en gran medida con su decisión a la autoexperimentación. Se hace especial mención a su rol pionero como investigador clínico y se remarca la necesidad de completar aquellos acontecimientos que formaron parte del funcionamiento del héroe en el tiempo histórico correspondiente.
    Keywords Medicine ; R
    Language English
    Publishing date 2016-12-01T00:00:00Z
    Publisher Colegio Médico del Perú
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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