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Book ; Online: Earth Observation in Forest Biophysical/Biochemical Parameter Retrieval

Srivastava, Prashant K / Malhi, Ramandeep Kaur M / Behera, Mukunda Dev / Kiran, G. Sandhya / Pandey, Prem Chandra / Petropoulos, George P

2023

Keywords	Research & information: general ; Biology, life sciences ; blue carbon ; hyperspectral data ; mangrove forest ; carbon stock ; Bhitarkanika Forest Reserve ; regression models ; machine learning ; P-band polarimetric interferometric synthetic aperture radar (Pol-InSAR) ; forest vertical structure ; Gaussian vertical backscatter (GVB) volume ; multi-baseline optimization ; symbolic regression ; random forest ; Sentinel-1 ; Sentinel-2 ; ICESat ; Bhitarkanika ; ATLAS ; ground topography in forested terrain ; laser intensity ; laser pointing angle ; UAV ; different altitudes ; multispectral ; biophysical parameters ; young oil palm ; lidar ; remote sensing ; forest structure ; stand volume ; stand dominant species ; spaceborne SAR ; multifrequency ; GEDI ; PolInSAR inversion ; forest height ; dynamic habitat index ; moderate resolution imaging spectroradiometer ; plant richness ; Indian biogeographic region ; phenology ; NDVI ; smoothing ; MODIS ; mixed forest in karst areas ; leaf N/P ratio ; fractional differentiation ; combined model ; overcome overfitting ; field spectroradiometer
Language	English
Size	1 electronic resource (216 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030722348
ISBN	9783036565262 ; 3036565264
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Effectiveness of hyperbaric oxygen therapy in the management of COVID-19-associated mucormycosis.

Pandey, Sandhya / Kumar, Vijay / Kumar, Ravi / Mishra, Brijesh / Singh, Anshu / Reddy, Gowtham

Medical gas research

2023 Volume 14, Issue 2, Page(s) 87–88

MeSH term(s)	Humans ; Mucormycosis/therapy ; Hyperbaric Oxygenation ; COVID-19/therapy ; Combined Modality Therapy
Language	English
Publishing date	2023-10-20
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2616230-1
ISSN	2045-9912 ; 2045-9912
ISSN (online)	2045-9912
ISSN	2045-9912
DOI	10.4103/2045-9912.385442
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Article: Bowen's Disease of the Palm and Its Management with In-step Graft.

Pandey, Sandhya / Friji, M T / Mohapatra, Devi P / Chittoria, Ravi K

Journal of cutaneous and aesthetic surgery

2021 Volume 14, Issue 4, Page(s) 449–451

Abstract: Bowen's disease is ... ...

Abstract	Bowen's disease is an
Language	English
Publishing date	2021-07-31
Publishing country	India
Document type	Case Reports
ZDB-ID	2461107-4
ISSN	0974-5157 ; 0974-2077
ISSN (online)	0974-5157
ISSN	0974-2077
DOI	10.4103/JCAS.JCAS_50_20
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Article ; Online: Development and use of miRNA-derived SSR markers for the study of genetic diversity, population structure, and characterization of genotypes for breeding heat tolerant wheat varieties.

Tyagi, Sandhya / Kumar, Anuj / Gautam, Tinku / Pandey, Renu / Rustgi, Sachin / Mir, Reyazul Rouf

PloS one

2021 Volume 16, Issue 2, Page(s) e0231063

Abstract: Heat stress is an important abiotic factor that limits wheat production globally, including south-east Asia. The importance of micro (mi) RNAs in gene expression under various biotic and abiotic stresses is well documented. Molecular markers, ... ...

Abstract	Heat stress is an important abiotic factor that limits wheat production globally, including south-east Asia. The importance of micro (mi) RNAs in gene expression under various biotic and abiotic stresses is well documented. Molecular markers, specifically simple sequence repeats (SSRs), play an important role in the wheat improvement breeding programs. Given the role of miRNAs in heat stress-induced transcriptional regulation and acclimatization, the development of miRNA-derived SSRs would prove useful in studying the allelic diversity at the heat-responsive miRNA-genes in wheat. In the present study, efforts have been made to identify SSRs from 96 wheat heat-responsive miRNA-genes and their characterization using a panel of wheat genotypes with contrasting reactions (tolerance/susceptible) to heat stress. A set of 13 miRNA-derived SSR markers were successfully developed as an outcome. These miRNA-SSRs are located on 11 different common wheat chromosomes (2A, 3A, 3B, 3D, 4D, 5A, 5B, 5D, 6A, 6D, and 7A). Among 13 miRNA-SSRs, seven were polymorphic on a set of 37 selected wheat genotypes. Within these polymorphic SSRs, three makers, namely HT-169j, HT-160a, and HT-160b, were found promising as they could discriminate heat-tolerant and heat-susceptible genotypes. This is the first report of miRNA-SSR development in wheat and their deployment in genetic diversity and population structure studies and characterization of trait-specific germplasm. The study suggests that this new class of molecular makers has great potential in the marker-assisted breeding (MAB) programs targeted at improving heat tolerance and other adaptability or developmental traits in wheat and other crops.
MeSH term(s)	Acclimatization/genetics ; Alleles ; Genetic Markers/genetics ; Genetic Variation/genetics ; Genotype ; Heat-Shock Response/genetics ; MicroRNAs/genetics ; Microsatellite Repeats/genetics ; Phenotype ; Phylogeny ; Plant Breeding ; Stress, Physiological/genetics ; Thermotolerance/genetics ; Triticum/genetics
Chemical Substances	Genetic Markers ; MicroRNAs
Language	English
Publishing date	2021-02-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0231063
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Development and use of miRNA-derived SSR markers for the study of genetic diversity, population structure, and characterization of genotypes for breeding heat tolerant wheat varieties.

Sandhya Tyagi / Anuj Kumar / Tinku Gautam / Renu Pandey / Sachin Rustgi / Reyazul Rouf Mir

PLoS ONE, Vol 16, Iss 2, p e

2021 Volume 0231063

Abstract	Heat stress is an important abiotic factor that limits wheat production globally, including south-east Asia. The importance of micro (mi) RNAs in gene expression under various biotic and abiotic stresses is well documented. Molecular markers, specifically simple sequence repeats (SSRs), play an important role in the wheat improvement breeding programs. Given the role of miRNAs in heat stress-induced transcriptional regulation and acclimatization, the development of miRNA-derived SSRs would prove useful in studying the allelic diversity at the heat-responsive miRNA-genes in wheat. In the present study, efforts have been made to identify SSRs from 96 wheat heat-responsive miRNA-genes and their characterization using a panel of wheat genotypes with contrasting reactions (tolerance/susceptible) to heat stress. A set of 13 miRNA-derived SSR markers were successfully developed as an outcome. These miRNA-SSRs are located on 11 different common wheat chromosomes (2A, 3A, 3B, 3D, 4D, 5A, 5B, 5D, 6A, 6D, and 7A). Among 13 miRNA-SSRs, seven were polymorphic on a set of 37 selected wheat genotypes. Within these polymorphic SSRs, three makers, namely HT-169j, HT-160a, and HT-160b, were found promising as they could discriminate heat-tolerant and heat-susceptible genotypes. This is the first report of miRNA-SSR development in wheat and their deployment in genetic diversity and population structure studies and characterization of trait-specific germplasm. The study suggests that this new class of molecular makers has great potential in the marker-assisted breeding (MAB) programs targeted at improving heat tolerance and other adaptability or developmental traits in wheat and other crops.
Keywords	Medicine ; R ; Science ; Q
Subject code	571
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Molecular subtypes of colorectal cancer

Manish Pratap Singh / Sandhya Rai / Ashutosh Pandey / Nand K. Singh / Sameer Srivastava

Genes and Diseases, Vol 8, Iss 2, Pp 133-

An emerging therapeutic opportunity for personalized medicine

2021 Volume 145

Abstract: Molecular subtypes-based therapies offer new potential framework for desired and precise outcome in clinical settings. Current treatment strategies in colorectal cancer are largely ‘one drug fit all’ model for patients that display same pathological ... ...

Abstract	Molecular subtypes-based therapies offer new potential framework for desired and precise outcome in clinical settings. Current treatment strategies in colorectal cancer are largely ‘one drug fit all’ model for patients that display same pathological conditions. However, CRC is a very heterogenous set of malignancy that does not support for above criteria. Each subtype displays different pathological and genetic signatures. Based on these features, therapeutic stratification for individual patients may be designed, which may ultimately lead to improved therapeutic outcomes. In this comprehensive review, we have attempted to briefly outline major CRC pathways. A detailed overview of molecular subtypes and their clinical significance has been discussed. Present and future methods, governing CRC subtyping in the era of personalized therapy with a special emphasis on CMS subtypes of CRC has been reviewed. Together, discovery and validation of new CRC patient stratification methods, screening for novel therapeutic targets, and enhanced diagnosis of CRC may improve the treatment outcome.
Keywords	Biomarkers ; CMS subtypes ; Immunotherapy ; Molecular screening ; Personalized medicine ; Medicine (General) ; R5-920 ; Genetics ; QH426-470
Subject code	616
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Childhood and Adolescent Sleep Awareness in Caregivers and Health Care Providers: A Community- and Hospital-Based Survey.

Rajan, Aswani / Chakrabarty, Biswaroop / Gulati, Sheffali / Jauhari, Prashant / Pandey, Ravindra Mohan / Tripathi, Manjari / Kabra, Sushil Kumar / Jain, Vandana / Sikka, Kapil / Zulfiqar, Luhar / Upadhyay, Ashish Datt / Gupta, Sandhya / Chandeliya, Kamlesh

Pediatric neurology

2023 Volume 147, Page(s) 14–23

Abstract: Background: Sleep disorders are common in childhood and adolescence with mental and physical consequences needing appropriate intervention by caregivers and health care providers (HCPs). The objective of the study, conducted at a tertiary teaching ... ...

Abstract	Background: Sleep disorders are common in childhood and adolescence with mental and physical consequences needing appropriate intervention by caregivers and health care providers (HCPs). The objective of the study, conducted at a tertiary teaching hospital and public school in north India, was to develop validated questionnaires to evaluate childhood and adolescent sleep awareness in caregivers and HCPs. Methods: The study participants (caregivers represented by parents of 2-18 year olds attending a public school and of those attending outpatient services at the study hospital and HCPs represented by medical interns and nursing graduates within 1 year of graduation) were enrolled after appropriate screening. Results: Two separate questionnaires in English for caregivers (also translated in Hindi) and HCPs were applied on 313 caregivers and 175 HCPs (110 medical interns and 65 nursing graduates) and developed and validated with a Cronbach α of 0.73 and 0.74, respectively. The questionnaires covered three domains: sleep hygiene, sleep related health problems, and miscellaneous. Both group of respondents had >50% correct responses in sleep hygiene. The ĸ agreement between knowledge and practice of sleep hygiene in caregivers was 0.2. Poor response (<50% correct responses) was seen in sleep-related health problems in both groups of respondents implying knowledge deficit in various sleep disorders. The HCPs performed poorly on basic theoretical questions in miscellaneous domain. For consultation of sleep problems, most caregivers (48%) chose pediatricians. Conclusion: There is a need to strengthen undergraduate medical and nursing curriculum in sleep. Caregivers should be made aware of implications of unhealthy sleep.
MeSH term(s)	Humans ; Adolescent ; Caregivers ; Health Personnel ; Surveys and Questionnaires ; Sleep Wake Disorders ; Sleep ; Hospitals
Language	English
Publishing date	2023-06-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	639164-3
ISSN	1873-5150 ; 0887-8994
ISSN (online)	1873-5150
ISSN	0887-8994
DOI	10.1016/j.pediatrneurol.2023.06.018
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Article ; Online: Biomass and carbon stock estimation across the timberline of Khangchendzonga National Park, Eastern Himalaya, India

Sandhya Rai / Aseesh Pandey / Hemant K. Badola

Taiwania, Vol 63, Iss 4, Pp 311-

2018 Volume 320

Abstract: Globally it is recognized that the productive capacity, energy potential and capability to sequester carbon of forests can be conveniently indicated by the forest biomass and its carbon stocks. For the first time, present study explored the timberlines ... ...

Abstract	Globally it is recognized that the productive capacity, energy potential and capability to sequester carbon of forests can be conveniently indicated by the forest biomass and its carbon stocks. For the first time, present study explored the timberlines of Khangchendzonga National Park, Eastern Himalaya, India, with an aim to assess the status of biomass and carbon stock. Along 3800 m asl to 4000 m asl, in Dzongri landscape, we assessed nine major timberline sites for the estimation of total basal area, aboveground biomass, belowground biomass, total carbon and stem density. The total basal area varied between 99.55±1.90 and 4.50±2.41m2 ha-1. The total above ground biomass differed between 279.25±3.04 and 15.35±7.38Mg ha-1, while the total below ground biomass ranged between 144.76±8.10 and 9.85±4.82Mg ha-1. The total carbon content estimated between 195.03±2.32 and 11.59±5.61 Mg ha-1. Among the studied environmental factors, elevation and humus were observed the determining factors for the tree growth and forest composition in the study area. The present investigation in the timberlines offers a potential platform for long term monitoring of climate change induced changes.
Keywords	Biomass ; Carbon stock ; Eastern Himalaya ; India ; Khangchendzonga National Park ; Timberline ; Biology (General) ; QH301-705.5
Subject code	333
Language	English
Publishing date	2018-10-01T00:00:00Z
Publisher	National Taiwan University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Topoisomerases: Resistance versus Sensitivity, How Far We Can Go?

Bansal, Sandhya / Bajaj, Priyanka / Pandey, Stuti / Tandon, Vibha

Medicinal research reviews

2017 Volume 37, Issue 2, Page(s) 404–438

Abstract: DNA topoisomerases are ubiquitously present remarkable molecular machines that help in altering topology of DNA in living cells. The crucial role played by these nucleases during DNA replication, transcription, and recombination vis-à-vis less sequence ... ...

Abstract	DNA topoisomerases are ubiquitously present remarkable molecular machines that help in altering topology of DNA in living cells. The crucial role played by these nucleases during DNA replication, transcription, and recombination vis-à-vis less sequence similarity among different species makes topoisomerases unique and attractive targets for different anticancer and antibacterial drugs. However, druggability of topoisomerases by the existing class of molecules is increasingly becoming questationable due to resistance development predominated by mutations in the corresponding genes. The current scenario facing a decline in the development of new molecules further comprises an important factor that may challenge topoisomerase-targeting therapy. Thus, it is imperative to wisely use the existing inhibitors lest with this rapid rate of losing grip over the target we may not go too far. Furthermore, it is important not only to design new molecules but also to develop new approaches that may avoid obstacles in therapies due to multiple resistance mechanisms. This review provides a succinct account of different classes of topoisomerase inhibitors, focuses on resistance acquired by mutations in topoisomerases, and discusses the various approaches to increase the efficacy of topoisomerase inhibitors. In a later section, we also suggest the possibility of using bisbenzimidazoles along with efflux pump inhibitors for synergistic bactericidal effects.
MeSH term(s)	DNA Topoisomerases/chemistry ; DNA Topoisomerases/metabolism ; Drug Resistance ; Humans ; Topoisomerase Inhibitors/pharmacology
Chemical Substances	Topoisomerase Inhibitors ; DNA Topoisomerases (EC 5.99.1.-)
Language	English
Publishing date	2017-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	603210-2
ISSN	1098-1128 ; 0198-6325
ISSN (online)	1098-1128
ISSN	0198-6325
DOI	10.1002/med.21417
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Article: Island Nasolabial Flap for Tongue Reconstruction: Locoregional Flap of Choice and an Alternative to Free Flap for Tongue Cancer.

Sharma, Vikas / Pandey, Sandhya / Gandhi, Ajeet Kumar / Pandey, Arun / Rastogi, Madhup / Sethi, Rohini / Hadi, Rahat / Hussain, Nuzhat

Indian journal of surgical oncology

2020 Volume 12, Issue 1, Page(s) 94–99

Abstract: Reconstruction following excision for tongue cancer carries important functional consequences. Island nasolabial flap (NLF) is robust and oncologically safe and has a good functional outcome, identical to free flap reconstruction. We retrospectively ... ...

Abstract	Reconstruction following excision for tongue cancer carries important functional consequences. Island nasolabial flap (NLF) is robust and oncologically safe and has a good functional outcome, identical to free flap reconstruction. We retrospectively analyzed the data of 11 tongue cancer patients operated between January 2019 and August 2019. Surgical resection and neck dissection followed by immediate reconstruction by island NLF were done. Post-operative functional outcome assessed using the University of Washington Quality of Life Questionnaire. Age of patients ranged between 39 and 70 years. All patients had either T2 or T3 tongue cancer. No incidence of flap necrosis noted in any patient. On an average, all were discharged between 3rd and 5th post-operative days. Cosmetic and functional outcomes were satisfactory in all patients. Island nasolabial has an excellent reach and can reach any part of the oral cavity, even to the contralateral side and base of the tongue. It has an excellent post-operative tongue function, almost equivalent to free flap. Hence, it should be considered locoregional flap of choice for tongue reconstruction.
Language	English
Publishing date	2020-09-17
Publishing country	India
Document type	Journal Article
ZDB-ID	2568289-1
ISSN	0976-6952 ; 0975-7651
ISSN (online)	0976-6952
ISSN	0975-7651
DOI	10.1007/s13193-020-01214-3
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