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  1. Article: Breakthroughs in Oral and Maxillofacial Surgery.

    Antonelli, Alessandro / Bennardo, Francesco / Giudice, Amerigo

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: In the field of oral and maxillofacial surgery, continuous advances have ushered in a new era of innovation, profoundly influencing this branch of medicine [ ... ]. ...

    Abstract In the field of oral and maxillofacial surgery, continuous advances have ushered in a new era of innovation, profoundly influencing this branch of medicine [...].
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Three-dimensional facial swelling evaluation of pre-operative single-dose of prednisone in third molar surgery: a split-mouth randomized controlled trial.

    Antonelli, Alessandro / Barone, Selene / Bennardo, Francesco / Giudice, Amerigo

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 614

    Abstract: Background: Facial swelling, pain, and trismus are the most common postoperative sequelae after mandibular third molar (M3M) surgery. Corticosteroids are the most used drugs to reduce the severity of inflammatory symptoms after M3M surgery. This study ... ...

    Abstract Background: Facial swelling, pain, and trismus are the most common postoperative sequelae after mandibular third molar (M3M) surgery. Corticosteroids are the most used drugs to reduce the severity of inflammatory symptoms after M3M surgery. This study aimed to evaluate the effect of a single pre-operative dose of prednisone on pain, trismus, and swelling after M3M surgery.
    Methods: This study was designed as a split-mouth randomized, controlled, triple-blind trial with two treatment groups, prednisone (PG) and control (CG). All the parameters were assessed before the extraction (T0), two days (T1), and seven days after surgery (T2). Three-dimensional evaluation of facial swelling was performed with Bellus 3D Face App. A visual analogue scale (VAS) was used to assess pain. The maximum incisal distance was recorded with a calibrated rule to evaluate the trismus. The Shapiro-Wilk test was used to evaluate the normal distribution of each variable. To compare the two study groups, the analysis of variance was performed using a two-tailed Student t-test for normal distributions. The level of significance was set at a = 0.05. Statistical analysis was conducted using the software STATA (STATA 11, StataCorp, College Station, TX).
    Results: Thirty-two patients were recruited with a mean age of 23.6 ± 3.7 years, with a male-to-female ratio of 1:3. A total of 64 M3Ms (32 right and 32 left) were randomly assigned to PG or CG. Surgery time recorded a mean value of 15.6 ± 3.7 min, without statistically significant difference between the groups. At T1, PG showed a significantly lower facial swelling compared to CG (PG: 3.3 ± 2.1 mm; CG: 4.2 ± 1.7 mm; p = 0.02). Similar results were recorded comparing the groups one week after surgery (PG: 1.2 ± 1.2; CG: 2.1 ± 1.3; p = 0.0005). All patients reported a decrease in facial swelling from T1 to T2 without differences between the two groups. At T1, the maximum buccal opening was significantly reduced than T0, and no difference between PG (35.6 ± 8.2 mm) and CG (33.7 ± 7.3 mm) (p > 0.05) was shown. Similar results were reported one week after surgery (PG: 33.2 ± 14.4 mm; CG: 33.7 ± 13.1 mm; p > 0.05). PG showed significantly lower pain values compared to CG, both at T1 (PG: 3.1 ± 1.5; CG: 4.6 ± 1.8; p = 0.0006) and T2 (PG: 1.0 ± 0.8; CG: 1.9 ± 1.4; p = 0.0063).
    Conclusion: Our results showed that pre-operative low-dose prednisone administration could reduce postoperative sequelae by improving patient comfort after M3M surgery and reducing facial swelling two days and one week after surgical procedures.
    Trial registration: www.
    Clinicaltrials: gov - NCT05830747 retrospectively recorded-Date of registration: 26/04/2023.
    MeSH term(s) Humans ; Female ; Male ; Young Adult ; Adult ; Prednisone/therapeutic use ; Molar, Third/surgery ; Trismus/prevention & control ; Retrospective Studies ; Mouth ; Disease Progression ; Pain
    Chemical Substances Prednisone (VB0R961HZT)
    Language English
    Publishing date 2023-08-31
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03334-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Oral mucous membrane pemphigoid after SARS-CoV-2 vaccination.

    Calabria, Elena / Antonelli, Alessandro / Lavecchia, Annamaria / Giudice, Amerigo

    Oral diseases

    2022  Volume 30, Issue 2, Page(s) 782–783

    MeSH term(s) Humans ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Mucous Membrane ; Oral Ulcer/chemically induced ; Pemphigoid, Benign Mucous Membrane/chemically induced ; Pemphigoid, Bullous/chemically induced ; Vaccination/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-12-28
    Publishing country Denmark
    Document type Case Reports ; Letter
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14468
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  4. Article ; Online: Can different osteotomies have an influence on surgically assisted rapid maxillary expansion? A systematic review.

    Barone, Selene / Bennardo, Francesco / Salviati, Marianna / Calabria, Elena / Bocchino, Tecla / Michelotti, Ambra / Giudice, Amerigo

    Head & face medicine

    2024  Volume 20, Issue 1, Page(s) 16

    Abstract: The purpose of this study was to systematically review the randomized and non-randomized clinical trials (RCT; nRCT) concerning the different available osteotomies for surgically assisted rapid maxillary expansion (SARME): pterygomaxillary disjunction ( ... ...

    Abstract The purpose of this study was to systematically review the randomized and non-randomized clinical trials (RCT; nRCT) concerning the different available osteotomies for surgically assisted rapid maxillary expansion (SARME): pterygomaxillary disjunction (SARME + PD vs SARME-PD) and segmental Le Fort I osteotomy (2-piece vs 3-piece). Outcomes focused on skeletal, dental, upper airway changes, complications, and relapse. Two authors investigated five databases (PubMed, Cochrane Library, Google Scholar, Scopus, Web of Science) until August 2023. The Cochrane Collaboration Tool and the Newcastle-Ottawa scale were used for the quality assessment of the included RCTs and nRCTs, respectively. A total of 554 articles were retrieved and after duplicates removing and full-text reading, 40 studies were included. Two RCTs showed a low risk of bias, one an unclear risk and one a high risk. Among the non-RCTs, 15 studies showed a good quality, while 21 exhibited a fair quality score. SARME + PD resulted in more homogeneous posterior bone expansion, with minimal dental effects. No difference between 2-piece and 3-piece in asymmetric expansion was observed, although 3SO showed 1-2 mm of more transverse increase. The oropharynx minimum cross-sectional area, the nasopharynx and the oropharynx volume were greater in SARME + PD. Both dental and bone relapse can occur but no differences between the groups were observed. All osteotomies guaranteed a correction of transverse maxillary deficiency. Lower side effects were described in SARME + PD. Two-piece and 3-piece segmental Le Fort I osteotomies did not show any differences in the symmetry and amount of expansion.
    MeSH term(s) Humans ; Clinical Trials as Topic ; Maxilla/surgery ; Osteotomy, Le Fort ; Palatal Expansion Technique ; Recurrence ; Tooth
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2202219-3
    ISSN 1746-160X ; 1746-160X
    ISSN (online) 1746-160X
    ISSN 1746-160X
    DOI 10.1186/s13005-024-00415-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Short- and Long-Term Effects of Maxillary Expander with Tongue Crib in Growing Open-Bite and Skeletal Class II Patients: A Retrospective Study.

    Barone, Selene / Bennardo, Francesco / Diodati, Federica / Salviati, Marianna / Calabria, Elena / Colangeli, Walter / Antonelli, Alessandro / Giudice, Carmen / Giudice, Amerigo

    Dentistry journal

    2024  Volume 12, Issue 2

    Abstract: The purpose of this study was to evaluate short- and long-term changes in growing patients with Class II malocclusion and open bite after rapid maxillary expansion (RME). A retrospective cohort study was conducted with 16 growing patients with open-bite ... ...

    Abstract The purpose of this study was to evaluate short- and long-term changes in growing patients with Class II malocclusion and open bite after rapid maxillary expansion (RME). A retrospective cohort study was conducted with 16 growing patients with open-bite malocclusion enrolled in a group treated with a rapid maxillary expander (RME) with a crib (TG), and 16 untreated patients with similar malocclusion in the control group (CG). Cephalograms were recorded before starting the treatment (T0), at the end of the latency phase (T1), and before the fixed therapy (T2) in order to analyze skeletal and dental changes in vertical, transversal, and sagittal relationships. Statistical analysis was performed with α = 0.05 as level of significance. At the end of the active expansion (T1), all subjects in the TG showed a corrected overbite with a statistically significant difference compared to the CG (
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj12020022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Usefulness of wedge-shaped implants in the full-arch rehabilitation of severe maxillary atrophy: a case report.

    Giudice, Amerigo / Attanasio, Ferdinando / Bennardo, Francesco / Antonelli, Alessandro / Vercellotti, Tomaso

    The International journal of periodontics & restorative dentistry

    2023  

    Abstract: The management of marked horizontal bone atrophy represents a critical challenge for traditional implantology procedures. For this purpose, clinicians have developed several protocols and procedure to allow the most suitable and accurate surgical and ... ...

    Abstract The management of marked horizontal bone atrophy represents a critical challenge for traditional implantology procedures. For this purpose, clinicians have developed several protocols and procedure to allow the most suitable and accurate surgical and prosthetic implant rehabilitation. Despite the development of guided-bone regeneration methods or the use of small-diameter implants, the rehabilitation of thin bone areas represents a clinical dilemma for the medium- and long-term survival of implant-prosthetic therapies. This clinical case evaluates the use of wedge implants for the full arch rehabilitation of an atrophic maxilla with a thin ridge. This treatment choice allowed a minimally invasive rehabilitation, avoiding regenerative bone surgery, while respecting biological and prosthetic limits. Furthermore, the evaluation of ISQ and MBL values during the first year of follow-up allowed us to analyse the behaviour of this rehabilitation solution in full arch maxillary cases.
    Language English
    Publishing date 2023-10-11
    Publishing country United States
    Document type Journal Article
    ISSN 1945-3388
    ISSN (online) 1945-3388
    DOI 10.11607/prd.6453
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  7. Article ; Online: Accuracy of Zygomatic Implant Placement Using a Full Digital Planning and Custom-Made Bone-Supported Guide: A Retrospective Observational Cohort Study.

    Gallo, Francesco / Zingari, Francesco / Bolzoni, Alessandro / Barone, Selene / Giudice, Amerigo

    Dentistry journal

    2023  Volume 11, Issue 5

    Abstract: The aim of the study was to evaluate the accuracy of zygomatic implant placement using customized bone-supported laser-sintered titanium templates. Pre-surgical computed tomography (CT) scans allowed to develop the ideal virtual planning for each patient. ...

    Abstract The aim of the study was to evaluate the accuracy of zygomatic implant placement using customized bone-supported laser-sintered titanium templates. Pre-surgical computed tomography (CT) scans allowed to develop the ideal virtual planning for each patient. Direct metal laser-sintering was used to create the surgical guides for the implant placement. Post-operative CT scans were taken 6 months after surgery to assess any differences between the planned and placed zygomatic implants. Qualitative and quantitative three-dimensional analyses were performed with the software Slicer3D, recording linear and angular displacements after the surface registration of the planned and placed models of each implant. A total of 59 zygomatic implants were analyzed. Apical displacement showed a mean movement of 0.57 ± 0.49 mm on the X-axis, 1.1 ± 0.6 mm on the Y-axis, and 1.15 ± 0.69 mm on the Z-axis for the anterior implant, with a linear displacement of 0.51 ± 0.51 mm on the X-axis, 1.48 ± 0.9 mm on the Y-axis, and 1.34 ± 0.9 mm on the Z-axis for the posterior implant. The basal displacement showed a mean movement of 0.33 ± 0.25 mm on the X-axis, 0.66 ± 0.47 mm on the Y-axis, and 0.58 ± 0.4 mm on the Z-axis for the anterior implant, with a linear displacement of 0.39 ± 0.43 mm on the X-axis, 0.42 ± 0.35 mm on the Y-axis, and 0.66 ± 0.4 mm on the Z-axis for the posterior implant. The angular displacements recorded significative differences between the anterior implants (yaw: 0.56 ± 0.46°; pitch: 0.52 ± 0.45°; roll: 0.57 ± 0.44°) and posterior implants (yaw: 1.3 ± 0.8°; pitch: 1.3 ± 0.78°; roll: 1.28 ± 1.1°) (
    Language English
    Publishing date 2023-05-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj11050123
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  8. Article ; Online: Efficacy of rehabilitative therapies on otologic symptoms in patients with temporomandibular disorders: A systematic review of randomised controlled trials.

    Ferrillo, Martina / Marotta, Nicola / Viola, Pasquale / Chiarella, Giuseppe / Fortunato, Leonzio / Ammendolia, Antonio / Giudice, Amerigo / de Sire, Alessandro

    Journal of oral rehabilitation

    2024  

    Abstract: Background: The term temporomandibular disorder (TMD) indicates a set of musculoskeletal conditions involving temporomandibular joint (TMJ), masticatory musculature, and related anatomical structures. Pain is the most common clinical manifestation of ... ...

    Abstract Background: The term temporomandibular disorder (TMD) indicates a set of musculoskeletal conditions involving temporomandibular joint (TMJ), masticatory musculature, and related anatomical structures. Pain is the most common clinical manifestation of TMD, and the auditory system might be involved and affected, through tinnitus, dizziness, otalgia and ear fullness sensation.
    Objectives: The aim of this systematic review of randomised controlled trails (RCTs) was to evaluate the efficacy of rehabilitative approaches on otologic symptoms in patients with TMD.
    Methods: PubMed, Scopus and Web of Science were systematically searched from the inception until 8th October 2023 to identify RCTs presenting participants with a diagnosis of TMD associated with otologic signs and symptoms, rehabilitative approaches as interventions, and modification of the otological symptoms as outcome.
    Results: Out of 931 papers suitable for title/abstract screening, 627 articles were assessed for eligibility. Five studies were included reporting the efficacy of occlusal splint therapy, low-level laser therapies, and physical therapy in patients diagnosed whit secondary otalgia or tinnitus associated with TMD. No RCTs evaluating other otologic symptoms, ear fullness, dizziness or vertigo were found.
    Conclusions: Results of this systematic review suggested that rehabilitative approaches might be effective in improving secondary otalgia and tinnitus in TMD patients. Thus, further RCTs with a higher level of evidence and more representative samples should be conducted to better understand the effects of TMD therapy on otologic complains.
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 187079-8
    ISSN 1365-2842 ; 0305-182X
    ISSN (online) 1365-2842
    ISSN 0305-182X
    DOI 10.1111/joor.13716
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  9. Article: Incidence and management of condylar resorption after orthognathic surgery: An overview.

    Barone, Selene / Cosentini, Giorgio / Bennardo, Francesco / Antonelli, Alessandro / Giudice, Amerigo

    Korean journal of orthodontics

    2022  Volume 52, Issue 1, Page(s) 29–41

    Abstract: Objective: Condylar resorption (CR) is one of the major post-surgical complications of orthognathic surgery. This systematic review (SR) aimed to evaluate epidemiological data, risk factors, and therapeutical management of CR.: Methods: Six databases ...

    Abstract Objective: Condylar resorption (CR) is one of the major post-surgical complications of orthognathic surgery. This systematic review (SR) aimed to evaluate epidemiological data, risk factors, and therapeutical management of CR.
    Methods: Six databases were screened by two investigators until September 2020 to obtain all SRs. After reading the titles and abstracts, eligible SRs were determined and data extraction was performed. Using the latest version of A Measurement Tool to Assess Systematic Reviews, the methodological quality of the included SRs was determined.
    Results: Ten SRs with low or critically-low methodological quality were included in this review. Mandibular hypoplasia on the sagittal plane and hyperdivergent growth pattern on the vertical plane were the most common skeletal alterations in which CR could occur after orthognathic surgery. Post-operative condylar changes were analyzed both on two-dimensional and three-dimensional (3D) radiographic examinations. The incidence of CR was not related to the fixation method. Based on the severity of the pathological conditions, management of CR can include conservative or surgical therapy.
    Conclusions: Despite the limited evidence in literature, CR is considered a consequence of orthognathic surgery. However, an accurate diagnosis of CR and a better orthognathic surgical planning must include 3D radiographic examinations to improve pre- and post-surgical comparison. Well-designed studies with long-term follow-up and 3D data are needed to clarify the findings of this analysis..
    Language English
    Publishing date 2022-01-19
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2888152-7
    ISSN 2234-7518 ; 2234-7518 ; 1225-5610
    ISSN (online) 2234-7518
    ISSN 2234-7518 ; 1225-5610
    DOI 10.4041/kjod.2022.52.1.29
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  10. Article ; Online: Efficacy of SMAS flap technique to prevent Frey's syndrome and aesthetic outcomes. A retrospective cohort analysis.

    Cristofaro, Maria Giulia / Cordaro, Raffaella / Barca, Ida / Giudice, Amerigo

    Annali italiani di chirurgia

    2022  Volume 92, Page(s) 683–690

    Abstract: Aim: The aim of this retrospective cohort study was to evaluate the efficacy of Superficial Musculoaponeurotic System (SMAS) flap technique to prevent Frey's Syndrome (FS) and improve aesthetic outcomes following superficial parotidectomy.: Materials ... ...

    Abstract Aim: The aim of this retrospective cohort study was to evaluate the efficacy of Superficial Musculoaponeurotic System (SMAS) flap technique to prevent Frey's Syndrome (FS) and improve aesthetic outcomes following superficial parotidectomy.
    Materials and methods: A total of 140 patients were treated between January 2003 and December 2018 at the Maxillofacial Unit of Magna Graecia University of Catanzaro with Superficial Parotidectomy (SP) for benign tumor and divided in two groups: Group 1 (78 patients) underwent SMAS flap reconstruction of the parotid lodge through a modified facelift incision and Group 2 (62 patients) underwent to SP without the use of SMAS interposition through a Redon type incision.
    Results: Significant statistical difference concerning FS, transient facial nerve injury, facial paralysis, salivary fistula, haematoma and skin deepness were found between Group 1 and Group 2, (0,00% vs 6,45% [p < 0,036], 2,56% vs 16,12% [p = 0,005], 0,00% vs 9,67% [p= 0,006], 1,28% vs 9,67% [p= 0,044], 1,28% vs 19,35% [p = 0,0002]) respectively. No significant statistical differences between the two groups were observed about wound infections (3,84% vs 8,06% [p= 0,466]).
    Discussion: SP represents the gold standard for the surgical treatment of benign tumors of the parotid gland greater than 3,5 cm in size involving superficial portion of the gland, for the low rate of recurrences over time and lower incidence of transient or permanent facial paralysis to which this technique leads. However, SP is not free from other complications such as FS, haematoma, salivary fistula and aesthetic results like facial contour deformity due to surgical site depression and visible scar. A reconstructive technique to reduce the impact of complications after SP is the SMAS flap because its preparation is easy, contextual to the parotidectomy and increases a little the surgical time.
    Conclusions: This study highlights the advantages of SMAS flap technique in reducing complications following parotid surgery, particularly FS, and in improving the quality of life.
    Key words: Frey's Syndrome, Minor test, Parotid benign tumor, SMAS flap, Superficial parotidectomy.
    MeSH term(s) Cohort Studies ; Esthetics ; Humans ; Parotid Gland/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control ; Quality of Life ; Retrospective Studies ; Superficial Musculoaponeurotic System ; Sweating, Gustatory/etiology ; Sweating, Gustatory/prevention & control
    Language English
    Publishing date 2022-02-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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