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Article ; Online: The "Hand as Foot" teaching method in the Lauge-Hansen classification of ankle fractures.

Wang, Lihang / Li, Deer / Ni, Xiyu / Sun, Guanwen

2023 Volume 46, Issue 9, Page(s) 3881–3882

MeSH term(s)	Humans ; Ankle Fractures ; Lower Extremity ; Foot ; Hand
Language	English
Publishing date	2023-04-14
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2023.03.152
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Article ; Online: New Parameter Derived from the Hansen Solubility Parameter Used to Evaluate the Solubility of Asphaltene in Solvent.

Li, Maolin / Ren, Taixin / Sun, Yudong / Xiao, Shengyu / Wang, Yuxin / Lu, Mingxing / Zhang, Shuai / Du, Kang

ACS omega

2022 Volume 7, Issue 16, Page(s) 13801–13807

Abstract: In order to determine whether asphaltenes dissolved in certain solvents, the Hansen solubility ...

Abstract	In order to determine whether asphaltenes dissolved in certain solvents, the Hansen solubility parameters (HSPs) of asphaltenes and maltenes extracted from SZ36-1 vacuum residual were measured, and a new parameter Δδ
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c00018
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Article ; Online: Evaluating the Exfoliation Efficiency of Quasi-2D Metal Diboride Nanosheets Using Hansen Solubility Parameters.

Gilliam, Matthew S / Yousaf, Ahmed / Guo, Yuqi / Li, Duo O / Momenah, AbdulAziz / Wang, Qing Hua / Green, Alexander A

Langmuir : the ACS journal of surfaces and colloids

2021 Volume 37, Issue 3, Page(s) 1194–1205

Abstract: ... from more conventional nanosheets produced from layered vdW compounds. Here in this paper we use Hansen ...

Abstract	Non-van der Waals (non-vdW) solids are emerging sources of two-dimensional (2D) nanosheets that can be produced via liquid-phase exfoliation (LPE), and are beginning to expand our understanding of 2D and quasi-2D materials. Recently, nanosheets formed by LPE processing of bulk metal diborides, a diverse family of layered non-vdW ceramic materials, have been reported. However, detailed knowledge of the exfoliation efficiency of these nanomaterials is lacking, and is important for their effective solution-phase processing and for understanding their fundamental surface chemistry, since they have significant differences from more conventional nanosheets produced from layered vdW compounds. Here in this paper we use Hansen solubility theory to investigate nanosheets of the metal borides CrB
Language	English
Publishing date	2021-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.0c03138
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Article ; Online: New Parameter Derived from the Hansen Solubility Parameter Used to Evaluate the Solubility of Asphaltene in Solvent

Maolin Li / Taixin Ren / Yudong Sun / Shengyu Xiao / Yuxin Wang / Mingxing Lu / Shuai Zhang / Kang Du

ACS Omega, Vol 7, Iss 16, Pp 13801-

2022 Volume 13807

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Teaching method of "Simulated Wrist Exercise in Hyperextension Position" in Lauge-Hansen classification of ankle fractures: An orthopedics teaching experience.

He, Bin / Li, Qiang / Zhao, Jianmin / Liu, Rui / Li, Yizhou / Xu, Yafei / Zhen, Zhilong / Hao, Xiaodong / Zou, Dewei

Asian journal of surgery

2020 Volume 43, Issue 12, Page(s) 1200–1202

MeSH term(s)	Ankle Fractures/classification ; Education, Medical/methods ; Humans ; Orthopedics/education ; Teaching ; Wrist
Language	English
Publishing date	2020-10-16
Publishing country	China
Document type	Letter
ZDB-ID	1068461-x
ISSN	0219-3108 ; 1015-9584
ISSN (online)	0219-3108
ISSN	1015-9584
DOI	10.1016/j.asjsur.2020.09.019
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Article ; Online: Weber Ankle Fracture Classification System Yields Greatest Interobserver and Intraobserver Reliability Over AO/OTA and Lauge-Hansen Classification Systems Under Time Constraints in an Asian Population.

Glen, Liau Zi Qiang / Wong, Joel Yat Seng / Tay, Wei Xuan / Li, Tian Pei / Phua, Sean Kean Ann / Manohara, Ruben / Chee, Yu Han

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons

2022 Volume 62, Issue 3, Page(s) 505–510

Abstract: ... Lauge-Hansen and AO Foundation/Orthopaedic Trauma Association (AO/OTA) classification systems under time ... according to Weber, Lauge-Hansen and AO/OTA. Classifications were conducted over 4 successive weeks under ... for Lauge-Hansen; 0.28 to 0.49 and 0.13 to 0.37 for AO/OTA. Intraobserver agreement ranged from 0.83 to 0.85 ...

Abstract	No previous studies have evaluated the intra- and interobserver reliability between the Weber, Lauge-Hansen and AO Foundation/Orthopaedic Trauma Association (AO/OTA) classification systems under time constraints. This study compares the interobserver and intraobserver reliability of the aforementioned classification systems under simulated time constraints. Anteroposterior and lateral radiographs of ankle malleolar fractures from 80 consecutive patients from 2015 to 2016 were classified by 2 independent observers according to Weber, Lauge-Hansen and AO/OTA. Classifications were conducted over 4 successive weeks under timed (25-seconds) and untimed conditions, with 1-week gaps between each classification. Cohen's kappa and percentage agreement were calculated. Cohen's kappa for interobserver agreement ranged 0.67 to 0.67 and 0.59 to 0.73 for untimed and timed classifications for Weber; 0.38 to 0.47 and 0.44 to 0.50 for Lauge-Hansen; 0.28 to 0.49 and 0.13 to 0.37 for AO/OTA. Intraobserver agreement ranged from 0.83 to 0.85 and 0.78 to 0.79 for untimed and timed classifications for Weber; 0.46 to 0.65 and 0.59 to 0.73 for Lauge-Hansen; 0.42 to 0.63 and 0.40 to 0.51 for AO/OTA. Based on the Landis and Koch's benchmark scale, there was substantial agreement in the inter- and intraobserver variables for Weber; moderate agreement in inter- and intraobserver variables for Lauge-Hansen; fair and moderate agreement in inter- and intraobserver variables respectively for AO/OTA. Interobserver and intraobserver reliability was the most substantial for Weber, followed by Lauge-Hansen and AO/OTA. Time constraint did not have a statistically significant effect on the reliability of classifications. We recommend concurrent usage of the Weber and Lauge-Hansen system, since they demonstrate the greatest reliability and reproducibility, and confer better understanding of the fracture type, respectively.
MeSH term(s)	Humans ; Ankle Fractures/diagnostic imaging ; Reproducibility of Results ; Observer Variation ; Radiography ; Ankle Joint/diagnostic imaging
Language	English
Publishing date	2022-12-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1146972-9
ISSN	1542-2224 ; 1067-2516
ISSN (online)	1542-2224
ISSN	1067-2516
DOI	10.1053/j.jfas.2022.12.004
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Article ; Online: Effect of XlogP and hansen solubility parameters on the prediction of small molecule modified docetaxel, doxorubicin and irinotecan conjugates forming stable nanoparticles.

Xu, Mei-Qi / Zhong, Ting / Yao, Xin / Li, Zhuo-Yue / Li, Hui / Wang, Jing-Ru / Feng, Zhen-Han / Zhang, Xuan

Drug delivery

2021 Volume 28, Issue 1, Page(s) 1603–1615

Abstract: Small molecule-chemotherapeutic drug conjugate nanoparticles (SMCDC NPs) has a great advantage in improving drug loading. However, the factors which influence these conjugates forming stable nanoparticles (NPs) are currently unclear. In our previous ... ...

Abstract	Small molecule-chemotherapeutic drug conjugate nanoparticles (SMCDC NPs) has a great advantage in improving drug loading. However, the factors which influence these conjugates forming stable nanoparticles (NPs) are currently unclear. In our previous studies, we synthesized a series of fatty acid-paclitaxel conjugates and suggested that the changes in the hydrophobic parameters (XlogP), solubility parameters and crystallinity of these fatty acid-paclitaxel conjugates were the key factors for affecting these small molecule-chemotherapeutic drug conjugates (SMCDCs) forming stable NPs in water. Here, we selected clinically widely used chemotherapeutic drug (docetaxel (DTX), doxorubicin (DOX) and irinotecan (Ir)) as model drug, and chose three straight-chain fatty acids (acetic acid (Ac), hexanoic acid (HA) and stearic acid (SA)) and one branched small molecule (N-(tert-butoxycarbonyl) glycine (B-G)) to synthesize 12 SMCDCs. Our results indicated that our prediction criterions obtained from paclitaxel conjugates were also appropriated for these synthesized SMCDCs. We suggested that the present studies expanded the scope of application of the above-mentioned influencing factors, provided research ideas for the rational design of SMCDC forming NPs and a basis for screening NPs with good anticancer activity.
MeSH term(s)	Acetic Acid/chemistry ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacology ; Caproates/chemistry ; Cell Survival ; Chemistry, Pharmaceutical ; Docetaxel/administration & dosage ; Docetaxel/pharmacology ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacology ; Drug Carriers/chemistry ; Drug Liberation ; Drug Stability ; Fatty Acids/chemistry ; Humans ; Hydrophobic and Hydrophilic Interactions ; Irinotecan/administration & dosage ; Irinotecan/pharmacology ; MCF-7 Cells ; Nanoparticles/chemistry ; Particle Size ; Solubility ; Stearic Acids/chemistry
Chemical Substances	Antineoplastic Agents ; Caproates ; Drug Carriers ; Fatty Acids ; Stearic Acids ; Docetaxel (15H5577CQD) ; hexanoic acid (1F8SN134MX) ; stearic acid (4ELV7Z65AP) ; Irinotecan (7673326042) ; Doxorubicin (80168379AG) ; Acetic Acid (Q40Q9N063P)
Language	English
Publishing date	2021-07-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1213261-5
ISSN	1521-0464 ; 1071-7544
ISSN (online)	1521-0464
ISSN	1071-7544
DOI	10.1080/10717544.2021.1958107
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Article: Evaluating the Exfoliation Efficiency of Quasi-2D Metal Diboride Nanosheets Using Hansen Solubility Parameters

Gilliam, Matthew S / Yousaf, Ahmed / Guo, Yuqi / Li, Duo O / Momenah, AbdulAziz / Wang, Qing Hua / Green, Alexander A

Langmuir. 2021 Jan. 11, v. 37, no. 3

2021

Abstract: ... from more conventional nanosheets produced from layered vdW compounds. Here in this paper we use Hansen ... dispersions in 33 different solvents, we determine Hansen solubility parameters (δD, δP, δH ...

Abstract	Non-van der Waals (non-vdW) solids are emerging sources of two-dimensional (2D) nanosheets that can be produced via liquid-phase exfoliation (LPE), and are beginning to expand our understanding of 2D and quasi-2D materials. Recently, nanosheets formed by LPE processing of bulk metal diborides, a diverse family of layered non-vdW ceramic materials, have been reported. However, detailed knowledge of the exfoliation efficiency of these nanomaterials is lacking, and is important for their effective solution-phase processing and for understanding their fundamental surface chemistry, since they have significant differences from more conventional nanosheets produced from layered vdW compounds. Here in this paper we use Hansen solubility theory to investigate nanosheets of the metal borides CrB₂ and MgB₂ derived from LPE. By preparing dispersions in 33 different solvents, we determine Hansen solubility parameters (δD, δP, δH) for both these metal diborides. We find that they exhibit notably higher δP and δH values compared to conventional vdW materials such as graphene and MoS₂, likely as a result of the types of bonds broken in such materials from exfoliation which allows for more favorable interactions with more polar and hydrogen-bonding solvents. We apply the solubility parameters to identify cosolvent blends suitable for CrB₂ and MgB₂ that produce dispersions with concentrations that match or exceed those of the top-performing individual solvents for each material and that have markedly higher stability compared to the constituent solvents of the blends alone. This work provides insight into the exfoliation effectiveness of different solvents for preparation of nanosheets from metal diborides and non-vdW materials in general. Such knowledge will be crucial for developing liquid-phase exfoliation strategies for incorporating these materials in applications such as nanocomposites, inks, and coatings.
Keywords	ceramics ; graphene ; hydrogen bonding ; nanocomposites ; nanosheets ; solubility
Language	English
Dates of publication	2021-0111
Size	p. 1194-1205.
Publishing place	American Chemical Society
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.0c03138
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effect of XlogP and Hansen Solubility Parameters on Small Molecule Modified Paclitaxel Anticancer Drug Conjugates Self-Assembled into Nanoparticles.

Zhong, Ting / Hao, Yan-Li / Yao, Xin / Zhang, Shuang / Duan, Xiao-Chuan / Yin, Yi-Fan / Xu, Mei-Qi / Guo, Yang / Li, Zhan-Tao / Zheng, Xiu-Chai / Li, Hui / Zhang, Xuan

Bioconjugate chemistry

2018 Volume 29, Issue 2, Page(s) 437–444

Abstract: ... NPs) as therapeutic NP platforms for cancer treatment. Here we demonstrate that the XlogP and Hansen ...

Abstract	Small molecule modified anticancer drug conjugates (SMMDCs) can self-assemble into nanoparticles (NPs) as therapeutic NP platforms for cancer treatment. Here we demonstrate that the XlogP and Hansen solubility parameters of paclitaxel (PTX) SMMDCs is essential for SMMDCs self-assembling into NPs. The amorphous state of PTX SMMDCs will also affect SMMDCs self-assembling into NPs. However, the antitumor activity of these PTX SMMDCs NPs decreased along with their XlogP values, indicating that a suitable XlogP value for designing the SMMDCs is important for self-assembling into NPs and for possessing antitumor activity. For higher level XlogP SMMDCs, a degradable linker should be considered in the design of SMMDCs to overcome the problem of lower antitumor activity. It is preferable that the hydrophilic groups in the SMMDCs should be present on the surface of self-assembling NPs.
MeSH term(s)	Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/drug therapy ; Cell Survival/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; MCF-7 Cells ; Nanoparticles/chemistry ; Paclitaxel/analogs & derivatives ; Paclitaxel/pharmacology ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Solubility
Chemical Substances	Antineoplastic Agents ; Small Molecule Libraries ; Paclitaxel (P88XT4IS4D)
Language	English
Publishing date	2018-01-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1024041-x
ISSN	1520-4812 ; 1043-1802
ISSN (online)	1520-4812
ISSN	1043-1802
DOI	10.1021/acs.bioconjchem.7b00767
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Article: Solubility Parameter of Ionic Liquids: A Comparative Study of Inverse Gas Chromatography and Hansen Solubility Sphere

Zhao, Li / Ma, KongJun / Wang, Qiang

ACS sustainable chemistry & engineering. 2019 May 17, v. 7, no. 12

2019

Abstract: ... The second is the Hansen solubility sphere method, which determined the Hansen solubility parameters (HSPs ... that the Hansen solubility sphere method provides higher values of the solubility parameters, while the IGC method ... by the method of IGC, and the results exhibit good agreement with those derived from the Hansen solubility ...

Abstract	The solubility parameters of four ionic liquids (ILs), 1-ethyl-3-methylimidazolium methyl sulfate ([EMIM][MeSO4]), 1-butyl-3-methylimidazolium methyl sulfate ([BMIM][MeSO4]), 1-hexyl-3-methylimidazolium methyl sulfate ([HMIM][MeSO4]), and 1-octyl-3-methylimidazolium methyl sulfate ([OMIM][MeSO4]), were estimated using two complementary methods. The first is an inverse gas chromatography (IGC) method, which determined the Hildebrand solubility parameters of four ILs based on a series of formulaic calculations. The second is the Hansen solubility sphere method, which determined the Hansen solubility parameters (HSPs) of the four ILs based on solubility testing of four ILs in 30 pure solvents. The results showed that the Hansen solubility sphere method provides higher values of the solubility parameters, while the IGC method presents lower values. In addition, the miscibilities of ILs in various solvents were evaluated by the method of IGC, and the results exhibit good agreement with those derived from the Hansen solubility sphere method. It is confirmed that the IGC and Hansen solubility sphere methods can be used to determine the solubility parameters of the ILs and were useful for solvent selection.
Keywords	comparative study ; gas chromatography ; ionic liquids ; solubility ; sulfates
Language	English
Dates of publication	2019-0517
Size	p. 10544-10551.
Publishing place	American Chemical Society
Document type	Article
ISSN	2168-0485
DOI	10.1021/acssuschemeng.9b01093
Database	NAL-Catalogue (AGRICOLA)

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