LIVIVO - Search results -

Search results

Result 1 - 10 of total 371

Search options

Article ; Online: The GAD-7 and the PHQ-8 exhibit the same mathematical pattern of item responses in the general population: analysis of data from the National Health Interview Survey.

Tomitaka, Shinichiro / Furukawa, Toshiaki A

2021 Volume 9, Issue 1, Page(s) 149

Abstract: Background: Recent studies have shown that, among the general population, responses to depression-rating scales follow a common mathematical pattern. However, the mathematical pattern among responses to the items of the Generalized Anxiety Disorder-7 ( ... ...

Abstract	Background: Recent studies have shown that, among the general population, responses to depression-rating scales follow a common mathematical pattern. However, the mathematical pattern among responses to the items of the Generalized Anxiety Disorder-7 (GAD-7) is currently unknown. The present study investigated whether item responses to the GAD-7, when administered to the general population, follow the same mathematical distribution as those of depression-rating scales. Methods: We used data from the 2019 National Health Interview Survey (31,997 individuals), which is a nationwide survey of adults conducted annually in the United States. The patterns of item responses to the GAD-7 and the Patient Health Questionnaire-8 (PHQ-8), respectively, were analyzed inductively. Results: For all GAD-7 items, the frequency distribution for each response option ("not at all," "several days," "more than half the days," and "nearly every day," respectively) was positively skewed. Line charts representing the responses to each GAD-7 item all crossed at a single point between "not at all" and "several days" and, on a logarithmic scale, showed a parallel pattern from "several days" to "nearly every day." This mathematical pattern among the item responses was identical to that of the PHQ-8. This characteristic pattern of the item responses developed because the values for the "more than half the days" to "several days" ratio were similar across all items, as were the values for the "nearly every day" to "more than half the days" ratio. Conclusions: Our results suggest that the symptom criteria of generalized anxiety disorder and major depression have a common distribution pattern in the general population.
MeSH term(s)	Adult ; Anxiety Disorders ; Depressive Disorder, Major ; Humans ; Patient Health Questionnaire ; Surveys and Questionnaires
Language	English
Publishing date	2021-09-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2705921-2
ISSN	2050-7283 ; 2050-7283
ISSN (online)	2050-7283
ISSN	2050-7283
DOI	10.1186/s40359-021-00657-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Mathematical pattern of Kessler psychological distress distribution in the general population of the U.S. and Japan.

Tomitaka, Shinichiro / Furukawa, Toshiaki A

BMC psychiatry

2021 Volume 21, Issue 1, Page(s) 188

Abstract: Background: Although the 6-item Kessler psychological scale (K6) is a useful depression screening scale in clinical settings and epidemiological surveys, little is known about the distribution model of the K6 score in the general population. Using four ... ...

Abstract	Background: Although the 6-item Kessler psychological scale (K6) is a useful depression screening scale in clinical settings and epidemiological surveys, little is known about the distribution model of the K6 score in the general population. Using four major national survey datasets from the United States and Japan, we explored the mathematical pattern of the K6 distributions in the general population. Methods: We analyzed four datasets from the National Health Interview Survey, the National Survey on Drug Use and Health, and the Behavioral Risk Factor Surveillance System in the United States, and the Comprehensive Survey of Living Conditions in Japan. We compared the goodness of fit between three models: exponential, power law, and quadratic function models. Graphical and regression analyses were employed to investigate the mathematical patterns of the K6 distributions. Results: The exponential function had the best fit among the three models. The K6 distributions exhibited an exponential pattern, except for the lower end of the distribution across the four surveys. The rate parameter of the K6 distributions was similar across all surveys. Conclusions: Our results suggest that, regardless of different sample populations and methodologies, the K6 scores exhibit a common mathematical distribution in the general population. Our findings will contribute to the development of the distribution model for such a depression screening scale.
MeSH term(s)	Humans ; Japan/epidemiology ; Psychological Distress ; Regression Analysis ; Stress, Psychological/epidemiology ; Substance-Related Disorders ; Surveys and Questionnaires ; United States/epidemiology
Language	English
Publishing date	2021-04-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1471-244X
ISSN (online)	1471-244X
DOI	10.1186/s12888-021-03198-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Shortening the Alzheimer's disease assessment scale cognitive subscale.

Levine, Stephen Z / Goldberg, Yair / Rotstein, Anat / Samara, Myrto / Yoshida, Kazufumi / Cipriani, Andrea / Iwatsubo, Takeshi / Leucht, Stefan / Furukawa, Toshiaki A

European psychiatry : the journal of the Association of European Psychiatrists

2024 Volume 67, Issue 1, Page(s) e19

Abstract: Background: A short yet reliable cognitive measure is needed that separates treatment and placebo for treatment trials for Alzheimer's disease. Hence, we aimed to shorten the : Methods: Secondary data analysis of participant-level data from five ... ...

Abstract	Background: A short yet reliable cognitive measure is needed that separates treatment and placebo for treatment trials for Alzheimer's disease. Hence, we aimed to shorten the Methods: Secondary data analysis of participant-level data from five pivotal clinical trials of donepezil compared with placebo for Alzheimer's disease (N = 2,198). Across all five trials, cognition was appraised using the original 11-item ADAS-Cog. Statistical analysis consisted of sample characterization, item response theory (IRT) to identify an ADAS-Cog short version, and mixed models for repeated-measures analysis to examine the effect sizes of ADAS-Cog change on the original and short versions in the placebo versus donepezil groups. Results: Based on IRT, a short ADAS-Cog was developed with seven items and two response options. The original and short ADAS-Cog correlated at baseline and at weeks 12 and 24 at 0.7. Effect sizes based on mixed modeling showed that the short and original ADAS-Cog separated placebo and donepezil comparably (ADAS-Cog original ES = 0.33, 95% CI = 0.29, 0.40, ADAS-Cog short ES = 0.25, 95% CI =0.23, 0.34). Conclusions: IRT identified a short ADAS-cog version that separated donepezil and placebo, suggesting its clinical potential for assessment and treatment monitoring.
MeSH term(s)	Humans ; Alzheimer Disease/diagnosis ; Alzheimer Disease/drug therapy ; Alzheimer Disease/psychology ; Donepezil/therapeutic use ; Cognition Disorders ; Cognition
Chemical Substances	Donepezil (8SSC91326P)
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1074337-6
ISSN	1778-3585 ; 0767-399X ; 0924-9338
ISSN (online)	1778-3585
ISSN	0767-399X ; 0924-9338
DOI	10.1192/j.eurpsy.2024.14
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2369: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 558: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Role of ABCB1 and ABCB4 in renal and biliary excretion of perfluorooctanoic acid in mice.

Furukawa, Kazuyoshi / Okamoto-Matsuda, Kahori / Harada, Kouji H / Minata, Mutsuko / Hitomi, Toshiaki / Kobayashi, Hatasu / Koizumi, Akio

Environmental health and preventive medicine

2024 Volume 29, Page(s) 21

Abstract: Background: Perfluorooctanoic acid (PFOA) is one of the major per- and polyfluoroalkyl substances. The role of ATP-binding cassette (ABC) transporters in PFOA toxicokinetics is unknown.: Methods: In this study, two ABC transporters, ABCB1 and ABCB4, ... ...

Abstract	Background: Perfluorooctanoic acid (PFOA) is one of the major per- and polyfluoroalkyl substances. The role of ATP-binding cassette (ABC) transporters in PFOA toxicokinetics is unknown. Methods: In this study, two ABC transporters, ABCB1 and ABCB4, were examined in mice with single intravenous PFOA administration (3.13 µmol/kg). To identify candidate renal PFOA transporters, we used a microarray approach to evaluate changes in gene expression of various kidney transporters in Abcb4 null mice. Results: Biliary PFOA concentrations were lower in Abcb4 null mice (mean ± standard deviation: 0.25 ± 0.12 µg/mL) than in wild-type mice (0.87 ± 0.02 µg/mL). Immunohistochemically, ABCB4 expression was confirmed at the apical region of hepatocytes. However, renal clearance of PFOA was higher in Abcb4 null mice than in wild-type mice. Among 642 solute carrier and ABC transporters, 5 transporters showed significant differences in expression between wild-type and Abcb4 null mice. These candidates included two major xenobiotic transporters, multidrug resistance 1 (Abcb1) and organic anion transporter 3 (Slc22a8). Abcb1 mRNA levels were higher in Abcb4 null mice than in wild-type mice in kidney. In Abcb4 null mice, Abcb1b expression was enhanced in proximal tubules immunohistochemically, while that of Slc22a8 was not. Finally, in Abcb1a/b null mice, there was a significant decrease in the renal clearance of PFOA (0.69 ± 0.21 vs 1.1 mL ± 0.37/72 h in wild-type mice). A homology search of ABCB1 showed that several amino acids are mutated in humans compared with those in rodents and monkeys. Conclusions: These findings suggest that, in the mouse, Abcb4 and Abcb1 are excretory transporters of PFOA into bile and urine, respectively.
MeSH term(s)	Humans ; Mice ; Animals ; Hepatobiliary Elimination ; ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/metabolism ; Fluorocarbons/toxicity ; Fluorocarbons/metabolism ; Kidney ; ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Caprylates
Chemical Substances	perfluorooctanoic acid (947VD76D3L) ; ATP-Binding Cassette Transporters ; Fluorocarbons ; ABCB1 protein, human ; ATP Binding Cassette Transporter, Subfamily B ; Caprylates
Language	English
Publishing date	2024-03-25
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2018758-0
ISSN	1347-4715 ; 1342-078X
ISSN (online)	1347-4715
ISSN	1342-078X
DOI	10.1265/ehpm.23-00284
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5232: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The characteristics of patients with severe social withdrawal 'Hikikomori' in two community psychiatry clinics in Japan.

Imai, Hissei / Takamatsu, Toko / Mitsuya, Hideaki / Mitsuya, Hidehiko / Furukawa, Toshiaki A

Asian journal of psychiatry

2021 Volume 65, Page(s) 102833

MeSH term(s)	Community Psychiatry ; Humans ; Japan ; Phobia, Social ; Shame ; Social Isolation
Language	English
Publishing date	2021-09-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2456678-0
ISSN	1876-2026 ; 1876-2018
ISSN (online)	1876-2026
ISSN	1876-2018
DOI	10.1016/j.ajp.2021.102833
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Measuring the performance of prediction models to personalize treatment choice.

Efthimiou, Orestis / Hoogland, Jeroen / Debray, Thomas P A / Seo, Michael / Furukawa, Toshiaki A / Egger, Matthias / White, Ian R

Statistics in medicine

2023 Volume 42, Issue 8, Page(s) 1188–1206

Abstract: When data are available from individual patients receiving either a treatment or a control intervention in a randomized trial, various statistical and machine learning methods can be used to develop models for predicting future outcomes under the two ... ...

Abstract	When data are available from individual patients receiving either a treatment or a control intervention in a randomized trial, various statistical and machine learning methods can be used to develop models for predicting future outcomes under the two conditions, and thus to predict treatment effect at the patient level. These predictions can subsequently guide personalized treatment choices. Although several methods for validating prediction models are available, little attention has been given to measuring the performance of predictions of personalized treatment effect. In this article, we propose a range of measures that can be used to this end. We start by defining two dimensions of model accuracy for treatment effects, for a single outcome: discrimination for benefit and calibration for benefit. We then amalgamate these two dimensions into an additional concept, decision accuracy, which quantifies the model's ability to identify patients for whom the benefit from treatment exceeds a given threshold. Subsequently, we propose a series of performance measures related to these dimensions and discuss estimating procedures, focusing on randomized data. Our methods are applicable for continuous or binary outcomes, for any type of prediction model, as long as it uses baseline covariates to predict outcomes under treatment and control. We illustrate all methods using two simulated datasets and a real dataset from a trial in depression. We implement all methods in the R package predieval. Results suggest that the proposed measures can be useful in evaluating and comparing the performance of competing models in predicting individualized treatment effect.
MeSH term(s)	Humans ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Precision Medicine ; Models, Statistical ; Clinical Decision Rules
Language	English
Publishing date	2023-01-26
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	843037-8
ISSN	1097-0258 ; 0277-6715
ISSN (online)	1097-0258
ISSN	0277-6715
DOI	10.1002/sim.9665
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1756: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer.

Hamada, Taiji / Higashi, Michiyo / Yokoyama, Seiya / Akahane, Toshiaki / Hisaoka, Masanori / Noguchi, Hirotsugu / Furukawa, Tatsuhiko / Tanimoto, Akihide

BMC cancer

2023 Volume 23, Issue 1, Page(s) 424

Abstract: Background: The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a cancer biomarker. Furthermore, fusion of the MALAT1 gene with glioma-associated oncogene 1 (GLI1) is a diagnostic marker of plexiform fibromyxoma ... ...

Abstract	Background: The long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a cancer biomarker. Furthermore, fusion of the MALAT1 gene with glioma-associated oncogene 1 (GLI1) is a diagnostic marker of plexiform fibromyxoma and gastroblastoma; however, the function of this fusion gene remains unexplored. Method: In this study, we elucidate the structure and function of the MALAT1::GLI1 fusion gene. To this end, we determined a transcriptional start site (TSS) and promoter region for truncated GLI1 expression using rapid amplification of the 5' cDNA end and a luciferase reporter assay in cultured cells transfected with a plasmid harboring the MALAT1::GLI1 fusion gene. Results: We found that the TATA box, ETS1 motif, and TSS were located in MALAT1 and that MALAT1 exhibited transcriptional activity and induced expression of GLI1 from the MALAT1::GLI1 fusion gene. Truncated GLI1, lacking SUMOylation and SUFU binding sites and located in the nucleus, upregulated mRNA expression of GLI1 target genes in the hedgehog signaling pathway. Conclusions: We demonstrate a distinct and alternative function of MALAT1 as a transcriptional promoter for expression of the MALAT1::GLI1 fusion gene. Our findings will aid future research on MALAT1 and its fusion gene partners.
MeSH term(s)	Humans ; Hedgehog Proteins/genetics ; Promoter Regions, Genetic ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Stomach Neoplasms/pathology ; Transcription Factors/genetics ; Zinc Finger Protein GLI1/genetics ; Zinc Finger Protein GLI1/metabolism
Chemical Substances	GLI1 protein, human ; Hedgehog Proteins ; RNA, Long Noncoding ; Transcription Factors ; Zinc Finger Protein GLI1 ; MALAT1 long non-coding RNA, human
Language	English
Publishing date	2023-05-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-023-10867-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Behavioral change stage might moderate the impact of multifaceted interventions on non-attendance from medical care among patients with type 2 diabetes: The Japan Diabetes Outcome Intervention Trial-2 Large-Scale Trial 007 (J-DOIT2-LT007).

Bouchi, Ryotaro / Noda, Mitsuhiko / Hayashino, Yasuaki / Goto, Atsushi / Yamazaki, Katsuya / Suzuki, Hikari / Furukawa, Toshiaki A / Izumi, Kazuo / Kobayashi, Masashi

Journal of diabetes investigation

2023 Volume 14, Issue 7, Page(s) 907–916

Abstract: Aims/introduction: Non-attendance from regular medical care is a major problem in diabetes patients. This study aimed to examine the impact of a multifaceted lifestyle intervention by face-to-face approach (FFA) on non-attendance from regular medical ... ...

Abstract	Aims/introduction: Non-attendance from regular medical care is a major problem in diabetes patients. This study aimed to examine the impact of a multifaceted lifestyle intervention by face-to-face approach (FFA) on non-attendance from regular medical care in comparison with that by telephone from the technical support center (TSC). Materials and methods: This was secondary analysis from a 1-year, prospective, cluster randomized, intervention study. Patients with type 2 diabetes, who were regularly visiting primary care physicians cluster-randomized into the control or intervention (TSC or FFA according to resource availability of the district medical associations) groups, were consecutively recruited. The primary end-point was non-attendance from regular medical care. The interaction between the type of intervention (TSC vs FFA) and behavioral change stage (pre- vs post-action stage) in diet and exercise for the dropout rate was assessed. Results: Among the 1,915 participants (mean age 56 ± 6 years; 36% women) enrolled, 828, 564 and 264 patients belonged to the control, TSC and FFA groups, respectively. We found evidence suggestive of an interaction between the intervention type and behavioral change stage in diet (P = 0.042) and exercise (P = 0.038) after adjusting for covariates. The hazard ratios (95% confidence interval) of FFA to TSC were 0.21 (0.05-0.93) and 7.69 (0.50-117.78) in the pre-action and post-action stages for diet, respectively, whereas they were 0.20 (0.05-0.92) and 4.75 (0.29-73.70) in the pre-action and post-action stages for exercise. Conclusions: Among diabetes patients, the impact of multifaceted intervention on non-attendance from medical care might differ by the behavioral change stage.
MeSH term(s)	Humans ; Female ; Middle Aged ; Male ; Diabetes Mellitus, Type 2/therapy ; Japan ; Prospective Studies ; Transtheoretical Model ; Life Style
Language	English
Publishing date	2023-04-05
Publishing country	Japan
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2625840-7
ISSN	2040-1124 ; 2040-1116
ISSN (online)	2040-1124
ISSN	2040-1116
DOI	10.1111/jdi.14012
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6920: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Association of HFA-PEFF score with clinical outcomes after catheter ablation for atrial fibrillation.

Okada, Taiji / Kitai, Takeshi / Kobori, Atsushi / Sano, Madoka / Murai, Ryosuke / Toyota, Toshiaki / Sasaki, Yasuhiro / Taniguchi, Tomohiko / Kim, Kitae / Ehara, Natsuhiko / Kinoshita, Makoto / Furukawa, Yutaka

Open heart

2024 Volume 11, Issue 1

Abstract: Background: The Heart Failure Association Pretest assessment, echocardiography and natriuretic peptide, functional testing and final aetiology (HFA-PEFF) score has been developed for diagnosing heart failure with preserved ejection fraction (HFpEF), ... ...

Abstract	Background: The Heart Failure Association Pretest assessment, echocardiography and natriuretic peptide, functional testing and final aetiology (HFA-PEFF) score has been developed for diagnosing heart failure with preserved ejection fraction (HFpEF), which is frequently associated with atrial fibrillation (AF). We aimed to investigate whether preprocedural HFA-PEFF score could be used to predict clinical outcomes in patients with AF who underwent catheter ablation (CA). Methods: Overall, 1679 patients with AF who underwent primary CA (71±10 years, 1218 males (72.5%), median follow-up duration 3.3 years) from July 2011 to December 2019 were included in this retrospective study. HFpEF was defined as an HFA-PEFF score ≥5. The primary study outcome was 5-year major adverse cardiovascular and cerebrovascular events (MACCE), which is a composite of all-cause death, hospitalisation for heart failure (HF) and hospitalisation for stroke. Results: The prevalence of HFpEF was 32.3%, but only 7.7% were diagnosed with HF at the time of CHADS Conclusions: Early detection of HFpEF using the HFA-PEFF score may have clinical applications in guiding therapeutic decision-making and improving prognosis by preventing HF and stroke in patients with AF undergoing CA.
MeSH term(s)	Male ; Humans ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Heart Failure/diagnosis ; Heart Failure/etiology ; Retrospective Studies ; Stroke Volume ; Stroke ; Catheter Ablation/adverse effects
Language	English
Publishing date	2024-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2747269-3
ISSN	2053-3624
ISSN	2053-3624
DOI	10.1136/openhrt-2023-002526
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Behavioral Activation Contributed to the Total Reduction of Depression Symptoms in the Smartphone-based Cognitive Behavioral Therapy: A Secondary Analysis of a Randomized, Controlled Trial.

Imai, Hissei / Yamada, Mitsuhiko / Inagaki, Masatoshi / Watanabe, Norio / Chino, Bun / Mantani, Akio / Furukawa, Toshiaki A

Innovations in clinical neuroscience

2021 Volume 17, Issue 7-9, Page(s) 21–25

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2021-01-14
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2675366-2
ISSN	2158-8341 ; 2158-8333
ISSN (online)	2158-8341
ISSN	2158-8333
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito