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  1. Article ; Online: Recurrent lower urinary tract infections in adults: don't think it is E. coli, don't choose ciprofloxacin to treat.

    Stompór, Tomasz

    Polish archives of internal medicine

    2020  Volume 130, Issue 5, Page(s) 369–370

    MeSH term(s) Adult ; Anti-Bacterial Agents ; Bacteria ; Ciprofloxacin ; Escherichia coli ; Humans ; Urinary Tract Infections
    Chemical Substances Anti-Bacterial Agents ; Ciprofloxacin (5E8K9I0O4U)
    Language English
    Publishing date 2020-05-29
    Publishing country Poland
    Document type Editorial ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15394
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Renalase in chronic kidney disease: the evolving story.

    Stompór, Tomasz

    Polish archives of internal medicine

    2020  Volume 130, Issue 1, Page(s) 89–90

    MeSH term(s) Erythrocytes ; Humans ; Monoamine Oxidase ; Renal Insufficiency, Chronic
    Chemical Substances Monoamine Oxidase (EC 1.4.3.4) ; renalase (EC 1.4.3.4.)
    Language English
    Publishing date 2020-01-31
    Publishing country Poland
    Document type Letter ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In search for the right way in medical care of older adults: navigating between geriatrician and other specialties on the sea of multimorbidity.

    Stompór, Małgorzata / Stompór, Tomasz

    Polish archives of internal medicine

    2021  Volume 131, Issue 12

    MeSH term(s) Aged ; Geriatricians ; Humans ; Medicine ; Multimorbidity
    Language English
    Publishing date 2021-12-22
    Publishing country Poland
    Document type Editorial ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.16167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Kidneys in heart failure: Impact of flozins.

    Stompór, Tomasz / Winiarska, Agata

    Kardiologia polska

    2023  Volume 81, Issue 11, Page(s) 1071–1080

    Abstract: Chronic kidney disease (CKD) and heart failure (HF) represent two modern diseases of civilization and are closely related. According to the concept of cardio-renal and reno-cardiac syndromes, most patients with CKD are affected by cardiovascular disease ( ...

    Abstract Chronic kidney disease (CKD) and heart failure (HF) represent two modern diseases of civilization and are closely related. According to the concept of cardio-renal and reno-cardiac syndromes, most patients with CKD are affected by cardiovascular disease (CVD), and CVD (including HF) is one of the factors not only promoting progression of established CKD but also triggering its onset and development. Treatment of CVD and HF in CKD patients remains challenging since CKD patients are characterized by extremely diverse and strongly expressed risk profiles, and the data from well-designed clinical trials addressing this population are scarce. Nevertheless, it seems that most of the drugs used in the treatment of CVD and HF (including beta-blockers, angiotensin-converting enzyme [ACE] inhibitors, angiotensin II receptor blocking agents, mineralocorticosteroid receptor antagonists, and sacubitril/valsartan) are of similar efficacy in patients with glomerular filtration rate (GFR) ranging between 45 and 60 ml/min/1.73 m² (although higher prevalence of side effects may limit their use). The data on cardiovascular (CV) drug efficacy in patients with lower GFR values (i.e. below 30-45 ml/min/1.73 m²) remain limited. In this review, we focused on the efficacy of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in the treatment of CVD and HF in CKD patients with or without diabetes. SGLT2i are clearly cardioprotective in a wide spectrum of estimated GFR although the data for HF patients with respect to urine albumin-creatinine ratio (UACR) are scarce, and for those with significantly reduced estimated GFR are still not available or not convincing, even after completion of large-scale high-quality major cardiovascular outcome trials (CVOT) in type 2 diabetes mellitus (T2DM) or trials with flozins in CKD and HF.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/drug therapy ; Heart Failure/complications ; Heart Failure/drug therapy ; Kidney ; Cardiovascular Diseases/drug therapy ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors
    Language English
    Publishing date 2023-11-08
    Publishing country Poland
    Document type Review ; Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/v.kp.97844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Abandonment of internal medicine as a specialty: the point of no return?

    Stompór, Tomasz

    Polskie Archiwum Medycyny Wewnetrznej

    2016  Volume 126, Issue 10, Page(s) 824–826

    MeSH term(s) Humans ; Internal Medicine/education ; Internal Medicine/trends
    Language English
    Publishing date 2016-10-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.3632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hypertensive kidney disease: a true epidemic or rare disease?

    Stompór, Tomasz / Perkowska-Ptasińska, Agnieszka

    Polish archives of internal medicine

    2020  Volume 130, Issue 2, Page(s) 130–139

    Abstract: In the industrialized world, hypertension affects approximately 30% of the general population. Hypertensive kidney disease is considered one of the consequences of long-term and poorly controlled hypertension. According to renal databases, it is a ... ...

    Abstract In the industrialized world, hypertension affects approximately 30% of the general population. Hypertensive kidney disease is considered one of the consequences of long-term and poorly controlled hypertension. According to renal databases, it is a leading cause of end‑stage renal failure, second only to diabetic kidney disease. We challenge this dogma by emphasizing lack of specificity of both clinical and morphological presentations of hypertension‑related kidney disease and very low prevalence of hypertensive kidney disease that is diagnosed based on kidney biopsy findings in registries. In most cases of concomitant hypertension and chronic kidney disease (CKD), the sequence of events (ie, which came first, CKD or hypertension) cannot be established. Arterial hypertension plays a role in the pathogenesis of chronic vascular disease and may occasionally lead to arterionephrosclerosis, but its general significance in the evolution of CKD and prevalence among CKD patients appear to be highly overestimated. Studies of the morphology of kidney biopsies have indicated that arterionephrosclerosis, classically considered a morphological equivalent of the clinical term "hypertensive kidney disease"(previously referred to as "hypertensive nephropathy"), most commonly superimposes upon variable chronic renal diseases, even in the absence of elevated blood pressure. To date, no prospective controlled clinical trials have been conducted in primary hypertension patients with renal events as primary endpoints. Data from available clinical trials with renal events that serve as secondary endpoints suggest that lowering blood pressure below current targets may provide additional cardiovascular benefits but may be harmful to the kidneys.
    MeSH term(s) Humans ; Hypertension/complications ; Kidney Failure, Chronic/etiology ; Renal Insufficiency, Chronic/etiology
    Language English
    Publishing date 2020-01-22
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Challenges for Polish Archives of Internal Medicine in 2021: what is new in 2022?

    Undas, Anetta / Gajos, Grzegorz / Stompór, Tomasz

    Polish archives of internal medicine

    2021  Volume 131, Issue 12

    MeSH term(s) Humans ; Internal Medicine ; Poland ; Societies, Medical
    Language English
    Publishing date 2021-12-22
    Publishing country Poland
    Document type Editorial
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.16176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Role of Sclerostin in Rheumatic Diseases: A Review.

    Jaśkiewicz, Łukasz / Chmielewski, Grzegorz / Kuna, Jakub / Stompór, Tomasz / Krajewska-Włodarczyk, Magdalena

    Journal of clinical medicine

    2023  Volume 12, Issue 19

    Abstract: Systemic connective tissue disorders constitute a heterogenous group of autoimmune diseases with the potential to affect a range of organs. Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune inflammatory disease affecting the joints. ... ...

    Abstract Systemic connective tissue disorders constitute a heterogenous group of autoimmune diseases with the potential to affect a range of organs. Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune inflammatory disease affecting the joints. Systemic lupus erythematosus (SLE) may manifest with multiple system involvement as a result of inflammatory response to autoantibodies. Spondyloarthropathies (SpAs) such as ankylosing spondylitis (AS) or psoriatic arthritis (PsA) are diseases characterised by the inflammation of spinal joints, paraspinal tissues, peripheral joints and enthesitis as well as inflammatory changes in many other systems and organs. Physiologically, sclerostin helps to maintain balance in bone tissue metabolism through the Wnt/β-catenin pathway, which represents a major intracellular signalling pathway. This review article aims to present the current knowledge on the role of sclerostin in the Wnt/β-catenin pathway and its correlation with clinical data from RA, SLE, AS and PsA patients.
    Language English
    Publishing date 2023-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Patterns of Dickkopf-3 Serum and Urine Levels at Different Stages of Chronic Kidney Disease.

    Dziamałek-Macioszczyk, Paulina / Winiarska, Agata / Pawłowska, Anna / Wojtacha, Paweł / Stompór, Tomasz

    Journal of clinical medicine

    2023  Volume 12, Issue 14

    Abstract: Dickkopf 3 (Dkk3) is a WNT/β-catenin signaling pathway regulator secreted by tubular epithelial cells upon the influence of different stressors. Recently Dkk3 was described as a biomarker of tubular cell injury and a tool that may estimate the risk of ... ...

    Abstract Dickkopf 3 (Dkk3) is a WNT/β-catenin signaling pathway regulator secreted by tubular epithelial cells upon the influence of different stressors. Recently Dkk3 was described as a biomarker of tubular cell injury and a tool that may estimate the risk of chronic kidney disease (CKD) progression. The data about Dkk3 concentrations at particular stages of CKD are lacking. The aim of this study was to measure serum and urine Dkk3 levels in patients with different 'renal status' and evaluate its role as a biomarker of renal damage. One hundred individuals, aged between 24 and 85 years (mean 53.1 ± 17.1), were enrolled in the study. Five groups of 20 subjects each were recruited based on their kidney function. Serum and urine Dkk3 levels were measured by ELISA. The highest median urinary Dkk3 normalized to urinary creatinine was found in patients with established CKD (7051 pg/mg). It was two times higher in renal transplant patients (5705 pg/mg) than in healthy individuals (2654 pg/mg) and the glomerulonephritis group (2470 pg/mg). Urinary Dkk3 was associated with serum creatinine in participants with established CKD and following transplantation. Our results confirm the potential role of Dkk3 as a biomarker of an ongoing renal injury.
    Language English
    Publishing date 2023-07-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12144705
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Kidney and heart: TGFβ1-mediated cross-talk.

    Stompór, Tomasz

    Kardiologia polska

    2013  Volume 71, Issue 2, Page(s) 129

    MeSH term(s) Angioplasty ; Cytokines/metabolism ; Diastole ; Female ; Humans ; Hypertrophy, Left Ventricular/prevention & control ; Male ; Renal Artery Obstruction/complications ; Renal Artery Obstruction/therapy ; Stents
    Chemical Substances Cytokines
    Language English
    Publishing date 2013
    Publishing country Poland
    Document type Comment ; Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.5603/KP.2013.0004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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