Article ; Online: Anastomotic leakage following resection of the esophagus-introduction of an endoscopic grading system.
World journal of surgical oncology
2022 Volume 20, Issue 1, Page(s) 104
Abstract: Background: Malignant tumors of the esophagus are the sixth leading cause of cancer-related deaths worldwide. Postoperative leakage of the esophago-gastrostomy leads to mediastinal sepsis, which is still associated with a high morbidity and mortality ... ...
| Abstract | Background: Malignant tumors of the esophagus are the sixth leading cause of cancer-related deaths worldwide. Postoperative leakage of the esophago-gastrostomy leads to mediastinal sepsis, which is still associated with a high morbidity and mortality rate. The aim of this study was to describe the endoscopic view of the different severity grades of an anastomotic leakage. Methods: Patients Between June 2016 and September 2018, 144 patients were operated upon in the Department of Surgery, University of Munich, Germany. Among these patients, 34 (23.6%) presented with a leakage of the anastomosis. Endoscopy In this retrospective analysis, the focus is to describe different patterns of leakage of the anastomosis. Results: We studied 34 patients in whom post-esophagectomy leakage of the anastomosis was detected and treated with an endoluminal vacuum sponge system. The leakage healed in 26 of 29 patients (success rate 89.7%). With the increasing severity of leakage, the treatment time and the in-hospital mortality correspondingly increased. Furthermore, the incidence of the development of a fistula to the tracheobronchial system increased with higher grades of leakage. Conclusions: Exact descriptions of leakage are necessary to compare the cases and to prove post-treatment improvement. This is, to our knowledge, the first publication to present a leakage grading score in patients after esophagectomy including reconstruction with a gastric tube. This new grading system needs to be tested in further analyses, with a special focus on prospective analysis. |
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| MeSH term(s) | Anastomotic Leak/etiology ; Endoscopy, Gastrointestinal ; Esophagectomy/adverse effects ; Esophagus/surgery ; Humans ; Retrospective Studies |
| Language | English |
| Publishing date | 2022-03-31 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2118383-1 |
| ISSN | 1477-7819 ; 1477-7819 |
| ISSN (online) | 1477-7819 |
| ISSN | 1477-7819 |
| DOI | 10.1186/s12957-022-02551-z |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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