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  1. Article ; Online: Preface to the series on oral pre-cancer and cancer.

    Patil, Shankargouda

    Translational cancer research

    2022  Volume 9, Issue 4, Page(s) 3073–3075

    Language English
    Publishing date 2022-01-20
    Publishing country China
    Document type Editorial
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr.2020.04.29
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  2. Article ; Online: Deepfakes in health care: Decoding digital deceptions.

    Patil, Shankargouda / Licari, Frank W

    Journal of the American Dental Association (1939)

    2024  

    Language English
    Publishing date 2024-05-08
    Publishing country England
    Document type Editorial
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.1016/j.adaj.2024.04.006
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  3. Article: sHPV-mediated oropharyngeal carcinogenesis: An overview.

    Patil, Shankargouda

    The Indian journal of medical research

    2022  Volume 156, Issue 4&5, Page(s) 687–688

    MeSH term(s) Humans ; Carcinogenesis/genetics ; Papillomaviridae ; Papillomavirus Infections/complications ; Papillomavirus Infections/genetics
    Language English
    Publishing date 2022-11-24
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_2507_20
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  4. Article ; Online: Climate change and the unforeseen challenges for dental practice.

    Licari, Frank W / Patil, Shankargouda

    Journal of the American Dental Association (1939)

    2024  Volume 155, Issue 3, Page(s) 191–192

    MeSH term(s) Humans ; Climate Change
    Language English
    Publishing date 2024-01-20
    Publishing country England
    Document type Editorial
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.1016/j.adaj.2023.12.005
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  5. Article: Potential Application of an Aqueous Extract of

    Patil, Shankargouda

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 12

    Abstract: The in vitro antifibrotic activity ... ...

    Abstract The in vitro antifibrotic activity of
    Language English
    Publishing date 2021-06-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14123374
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  6. Article ; Online: Caveat emptor: The dilemma of direct-to-consumer aligners.

    Patil, Shankargouda / Licari, Frank W / El-Bialy, Tarek

    Journal of the American Dental Association (1939)

    2024  Volume 155, Issue 5, Page(s) 357–359

    MeSH term(s) Humans ; Direct-to-Consumer Advertising
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article ; Editorial
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.1016/j.adaj.2024.02.007
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  7. Article ; Online: CD44 Sorted Cells Have an Augmented Potential for Proliferation, Epithelial-Mesenchymal Transition, Stemness, and a Predominantly Inflammatory Cytokine and Angiogenic Secretome

    Shankargouda Patil

    Current Issues in Molecular Biology, Vol 43, Iss 34, Pp 423-

    2021  Volume 433

    Abstract: Cancer stem cells (CSCs) have garnered attention with their potential for early diagnosis and prognosis of oral squamous cell carcinoma (OSCC). It is still indistinct whether CSCs are recognized with a specific set of characteristics. The present study ... ...

    Abstract Cancer stem cells (CSCs) have garnered attention with their potential for early diagnosis and prognosis of oral squamous cell carcinoma (OSCC). It is still indistinct whether CSCs are recognized with a specific set of characteristics. The present study aimed to assess the association of CD44 with stemness-related, Epithelial Mesenchymal Transition EMT-related genes and the secretome of the CSCs. The single-cell suspension from primary OSCC tumors was prepared by enzymatic digestion and the cells were cultured in-vitro. The cancer stem cells were isolated by CD44+ selection using magnetic cell-sorting. The expression of CD44, proliferation rate, gene expression of EMT-related transcription factors, stemness markers, cytokine levels and angiogenic factors in both cell population was assessed. The sorted CD44+ cells showed significantly higher proliferation rate than heterogenous population. The CD44 expression was >90% in the sorted cells which was higher than the heterogenous cells. The CD44+ CSCs cells demonstrated significant increased levels of EMT-related genes TWIST1 and CDH2 ( N -cadherin), CSC-related genes CD44 and CD133 (PROM1), stemness-related genes OCT4, SOX2, inflammatory cytokines IL-1ß, IL-12, IL-18 and TNF-α and angiogenic factors Angiopoietin-1, Angiopoietin-2, bFGF and VEGF while levels of epithelial gene CDH1 (E-cadherin) decreased in comparison to mixed cell population. The genetic and secretome profiling of the CD44+ CSCs could serve as diagnostic and prognostic tools in the treatment of oral cancers.
    Keywords cancer stem cells ; CD44 ; oral squamous cell carcinoma ; secretome ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: CD44 Sorted Cells Have an Augmented Potential for Proliferation, Epithelial-Mesenchymal Transition, Stemness, and a Predominantly Inflammatory Cytokine and Angiogenic Secretome.

    Patil, Shankargouda

    Current issues in molecular biology

    2021  Volume 43, Issue 1, Page(s) 423–433

    Abstract: Cancer stem cells (CSCs) have garnered attention with their potential for early diagnosis and prognosis of oral squamous cell carcinoma (OSCC). It is still indistinct whether CSCs are recognized with a specific set of characteristics. The present study ... ...

    Abstract Cancer stem cells (CSCs) have garnered attention with their potential for early diagnosis and prognosis of oral squamous cell carcinoma (OSCC). It is still indistinct whether CSCs are recognized with a specific set of characteristics. The present study aimed to assess the association of CD44 with stemness-related, Epithelial Mesenchymal Transition EMT-related genes and the secretome of the CSCs. The single-cell suspension from primary OSCC tumors was prepared by enzymatic digestion and the cells were cultured in-vitro. The cancer stem cells were isolated by CD44+ selection using magnetic cell-sorting. The expression of CD44, proliferation rate, gene expression of EMT-related transcription factors, stemness markers, cytokine levels and angiogenic factors in both cell population was assessed. The sorted CD44+ cells showed significantly higher proliferation rate than heterogenous population. The CD44 expression was >90% in the sorted cells which was higher than the heterogenous cells. The CD44+ CSCs cells demonstrated significant increased levels of EMT-related genes TWIST1 and CDH2 (
    MeSH term(s) Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Cell Proliferation/genetics ; Cell Separation/methods ; Cytokines/genetics ; Cytokines/metabolism ; Epithelial-Mesenchymal Transition/genetics ; Flow Cytometry/methods ; Gene Expression Regulation, Neoplastic ; Humans ; Hyaluronan Receptors/genetics ; Hyaluronan Receptors/metabolism ; Mouth Neoplasms/diagnosis ; Mouth Neoplasms/genetics ; Mouth Neoplasms/metabolism ; Neoplastic Stem Cells/metabolism ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction ; Secretome/metabolism
    Chemical Substances Biomarkers, Tumor ; CD44 protein, human ; Cytokines ; Hyaluronan Receptors
    Language English
    Publishing date 2021-06-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2000024-8
    ISSN 1467-3045 ; 1467-3037
    ISSN (online) 1467-3045
    ISSN 1467-3037
    DOI 10.3390/cimb43010034
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    Zs.A 5122: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: Game on! Gamification in dental education.

    Licari, Frank / Patil, Shankargouda

    Journal of dental education

    2022  Volume 86, Issue 12, Page(s) 1557–1558

    Language English
    Publishing date 2022-11-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 410579-5
    ISSN 1930-7837 ; 0022-0337
    ISSN (online) 1930-7837
    ISSN 0022-0337
    DOI 10.1002/jdd.13142
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    Zs.A 428: Show issues Location:
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  10. Article ; Online: Analyzing the Association between Candida Prevalence, Species Specificity, and Oral Squamous Cell Carcinoma

    Shankargouda Patil

    Applied Sciences, Vol 10, Iss 3, p

    A Systematic Review and Meta-Analysis— Candida and OSCC

    2020  Volume 1099

    Abstract: The present review is a qualitative and quantitative analysis of the overall prevalence of Candida , and its species specificity in oral squamous cell carcinoma (OSCC). PubMed, Scopus, and Web of Science databases were searched using the keywords ‘ ... ...

    Abstract The present review is a qualitative and quantitative analysis of the overall prevalence of Candida , and its species specificity in oral squamous cell carcinoma (OSCC). PubMed, Scopus, and Web of Science databases were searched using the keywords ‘ Candida and oral squamous cell carcinoma’. Only case-control observational studies in the English language evaluating the prevalence and species specificity of Candida in OSCC were included. 297 articles were identified (PubMed-106, Scopus-148, Web of Science-43) using the keywords. After screening the titles and abstracts, 206 articles were removed as they were duplicates (118) or irrelevant to the topic (88). Full text of the remaining 91 articles was assessed using the inclusion criteria, based on which only seven articles were included in the systematic review. For the quantitative analysis, the odds ratio and confidence interval were assessed and a forest plot was generated. Based on the meta-analysis, there is an association between the total Candida , Candida albicans ( CA ) and OSCC, while the association with non- Candida albicans (NCA) is relatively weak. The number of studies included in the meta-analysis was relatively low (four to five). Further, at least one of the studies included in the meta-analysis for the association of CA. , NCA and total Candida with OSCC had a Newcastle−Ottawa score below 7. Thus, although the results showed an association, the quality and quantity of the evidence may not be sufficient for conclusive inference.
    Keywords candida ; candida albicans ; oral squamous cell carcinoma ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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