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  1. Article: Candida albicans

    Richardson, Jonathan P

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 4

    Abstract: Fungal infections kill ~1 [ ... ]. ...

    Abstract Fungal infections kill ~1 [...].
    Language English
    Publishing date 2022-04-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11040459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Candida albicans

    Jonathan P. Richardson

    Pathogens, Vol 11, Iss 459, p

    A Major Fungal Pathogen of Humans

    2022  Volume 459

    Abstract: Fungal infections kill ~1 [.] ...

    Abstract Fungal infections kill ~1 [.]
    Keywords n/a ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Time-domain self-broadened and air-broadened nitrogen S-branch Raman linewidths at 80-200 K recorded in an underexpanded jet.

    Retter, Jonathan E / Koll, Matthew / Richardson, Daniel R / Kearney, Sean P

    The Journal of chemical physics

    2022  Volume 156, Issue 19, Page(s) 194201

    Abstract: We report pure-rotational ... ...

    Abstract We report pure-rotational N
    Language English
    Publishing date 2022-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0090613
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 49/16: Show issues

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  4. Article ; Online: Clinical and financial outcomes of transplant recipients following emergency general surgery operations.

    Tran, Zachary / Lee, Jonathan / Richardson, Shannon / Bakhtiyar, Syed Shahyan / Shields, Lauren / Benharash, Peyman

    Surgery open science

    2023  Volume 13, Page(s) 41–47

    Abstract: ... temporally (2010: 0.23 %, 2020: 0.36 %, p < 0.001) with : Conclusion: The incidence of transplant ...

    Abstract Introduction: Due to immunosuppression and underlying comorbidities, transplant recipients represent a vulnerable population following emergency general surgery (EGS) operations. The present study sought to evaluate clinical and financial outcomes of transplant patients undergoing EGS.
    Methods: The 2010-2020 Nationwide Readmissions Database was queried for adults (≥18 years) with non-elective EGS. Operations included bowel resection, perforated ulcer repair, cholecystectomy, appendectomy and lysis of adhesions. Patients were classified by transplant history (
    Results: Of 7,914,815 patients undergoing EGS, 25,278 (0.32 %) had prior transplantation. The incidence of transplant patients increased temporally (2010: 0.23 %, 2020: 0.36 %, p < 0.001) with
    Conclusion: The incidence of transplant recipients undergoing EGS operations has increased.
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article
    ISSN 2589-8450
    ISSN (online) 2589-8450
    DOI 10.1016/j.sopen.2023.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Implementation of Integrated Electronic Health Record Access for Prehospital Clinicians.

    O'Connor, Laurel / Hall, Michael / Smiley, Abbey / Richardson, Jonathan / McCluskey, Adam / Dufton, Jack / Sanseverino, Alexandra / Broach, John P

    The American journal of emergency medicine

    2023  Volume 74, Page(s) 182–184

    MeSH term(s) Humans ; Electronic Health Records ; Emergency Medical Services
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Letter
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2023.09.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2005: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Special Issue: Mucosal Fungal Infections.

    Richardson, Jonathan P / Naglik, Julian R

    Journal of fungi (Basel, Switzerland)

    2018  Volume 4, Issue 2

    Abstract: The past four decades have seen a staggering escalation in the number of invasive fungal infections worldwide.[ ... ]. ...

    Abstract The past four decades have seen a staggering escalation in the number of invasive fungal infections worldwide.[...].
    Language English
    Publishing date 2018-03-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof4020043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Response to comments by Dr Forero to our daring discourse.

    Lonnqvist, P A / Karmakar, Manoj Kumar / Richardson, Jonathan / Moriggl, Bernhard

    Regional anesthesia and pain medicine

    2020  Volume 46, Issue 9, Page(s) 837–838

    MeSH term(s) Humans ; Pain, Postoperative
    Language English
    Publishing date 2020-11-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2020-102216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2399: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Response to Dr Howle and collegues.

    Lonnqvist, P A / Karmakar, Manoj Kumar / Richardson, Jonathan / Moriggl, Bernhard

    Regional anesthesia and pain medicine

    2020  Volume 46, Issue 10, Page(s) 929–930

    MeSH term(s) Humans ; Nerve Block ; Pain, Postoperative
    Language English
    Publishing date 2020-11-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2020-102254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2399: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Fungal Toxins and Host Immune Responses.

    Brown, Rhys / Priest, Emily / Naglik, Julian R / Richardson, Jonathan P

    Frontiers in microbiology

    2021  Volume 12, Page(s) 643639

    Abstract: Fungi are ubiquitous organisms that thrive in diverse natural environments including soils, plants, animals, and the human body. In response to warmth, humidity, and moisture, certain fungi which grow on crops and harvested foodstuffs can produce ... ...

    Abstract Fungi are ubiquitous organisms that thrive in diverse natural environments including soils, plants, animals, and the human body. In response to warmth, humidity, and moisture, certain fungi which grow on crops and harvested foodstuffs can produce mycotoxins; secondary metabolites which when ingested have a deleterious impact on health. Ongoing research indicates that some mycotoxins and, more recently, peptide toxins are also produced during active fungal infection in humans and experimental models. A combination of innate and adaptive immune recognition allows the host to eliminate invading pathogens from the body. However, imbalances in immune homeostasis often facilitate microbial infection. Despite the wide-ranging effects of fungal toxins on health, our understanding of toxin-mediated modulation of immune responses is incomplete. This review will explore the current understanding of fungal toxins and how they contribute to the modulation of host immunity.
    Language English
    Publishing date 2021-04-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.643639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: In Vitro Biophysical Characterization of Candidalysin: A Fungal Peptide Toxin.

    Lee, Sejeong / Kichik, Nessim / Hepworth, Olivia W / Richardson, Jonathan P / Naglik, Julian R

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2542, Page(s) 163–176

    Abstract: In 2016, the first peptide toxin in any human fungal pathogen was identified. It was discovered in Candida albicans and was named candidalysin. Candidalysin is an amphipathic cationic peptide that damages cell membranes. Like most lytic peptides, ... ...

    Abstract In 2016, the first peptide toxin in any human fungal pathogen was identified. It was discovered in Candida albicans and was named candidalysin. Candidalysin is an amphipathic cationic peptide that damages cell membranes. Like most lytic peptides, candidalysin shows alpha-helical secondary structure. As the helicity and the membrane lytic activity of candidalysin are key factors for pathogenicity, here we describe in vitro approaches to monitor both its membrane-lytic function and the secondary structure. First, membrane permeabilization activity of candidalysin is measured in real time by direct electrical recording. Second, the secondary structure and helicity of candidalysin are determined by circular dichroism spectroscopy. These biophysical methods provide a means to characterize the activity and physical properties of candidalysin in vitro and will be useful in determining the structural and functional features of candidalysin and other similar cationic membrane-active peptides.
    MeSH term(s) Candida albicans/metabolism ; Circular Dichroism ; Fungal Proteins/metabolism ; Humans ; Mycotoxins/metabolism ; Peptides/metabolism ; Virulence
    Chemical Substances ECE1 protein, Candida albicans ; Fungal Proteins ; Mycotoxins ; Peptides
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2549-1_12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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