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  1. Article ; Online: THC and CBD: Similarities and differences between siblings.

    Stella, Nephi

    Neuron

    2023  Volume 111, Issue 3, Page(s) 302–327

    Abstract: ... ...

    Abstract Δ
    MeSH term(s) Humans ; Cannabidiol/adverse effects ; Dronabinol/pharmacology ; Siblings ; Cannabinoids ; Cannabinoid Receptor Agonists/pharmacology
    Chemical Substances Cannabidiol (19GBJ60SN5) ; Dronabinol (7J8897W37S) ; Cannabinoids ; Cannabinoid Receptor Agonists
    Language English
    Publishing date 2023-01-12
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 808167-0
    ISSN 1097-4199 ; 0896-6273
    ISSN (online) 1097-4199
    ISSN 0896-6273
    DOI 10.1016/j.neuron.2022.12.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interrogating the Impact of Δ

    Stella, Nephi

    Biological psychiatry

    2022  Volume 92, Issue 11, Page(s) 830–831

    MeSH term(s) Dronabinol/pharmacology ; Microglia
    Chemical Substances Dronabinol (7J8897W37S)
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2022.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The serine hydrolase ABHD6 controls survival and thermally induced seizures in a mouse model of Dravet syndrome.

    Westenbroek, Ruth / Kaplan, Joshua / Viray, Katie / Stella, Nephi

    Neurobiology of disease

    2023  Volume 180, Page(s) 106099

    Abstract: Evidence suggests that inhibition of α/β hydrolase-domain containing 6 (ABHD6) reduces seizures; however, the molecular mechanism of this therapeutic response remains unknown. We discovered that heterozygous expression of Abhd6 ( ... ...

    Abstract Evidence suggests that inhibition of α/β hydrolase-domain containing 6 (ABHD6) reduces seizures; however, the molecular mechanism of this therapeutic response remains unknown. We discovered that heterozygous expression of Abhd6 (Abhd6
    MeSH term(s) Animals ; Mice ; Epilepsies, Myoclonic/genetics ; Neurons ; gamma-Aminobutyric Acid ; Hydrolases/therapeutic use ; Serine ; NAV1.1 Voltage-Gated Sodium Channel/genetics ; Monoacylglycerol Lipases
    Chemical Substances gamma-Aminobutyric Acid (56-12-2) ; Hydrolases (EC 3.-) ; Serine (452VLY9402) ; NAV1.1 Voltage-Gated Sodium Channel ; Scn1a protein, mouse ; ABHD6 protein, mouse (EC 3.1.1.23) ; Monoacylglycerol Lipases (EC 3.1.1.23)
    Language English
    Publishing date 2023-03-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1211786-9
    ISSN 1095-953X ; 0969-9961
    ISSN (online) 1095-953X
    ISSN 0969-9961
    DOI 10.1016/j.nbd.2023.106099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A preclinical model of THC edibles that produces high-dose cannabimimetic responses.

    English, Anthony / Uittenbogaard, Fleur / Torrens, Alexa / Sarroza, Dennis / Slaven, Anna Veronica Elizabeth / Piomelli, Daniele / Bruchas, Michael R / Stella, Nephi / Land, Benjamin Bruce

    eLife

    2024  Volume 12

    Abstract: No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration ... ...

    Abstract No preclinical experimental approach enables the study of voluntary oral consumption of high-concentration Δ
    MeSH term(s) Mice ; Male ; Female ; Animals ; Dronabinol ; Reflex, Startle ; Hypothermia ; Gelatin/pharmacology ; Behavior, Animal
    Chemical Substances Dronabinol (7J8897W37S) ; Gelatin (9000-70-8)
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.89867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Mitosis exit followed by death in interphase prevents the development of polyploid giant cancer cells.

    Vicente, Juan Jesus / Khan, Kainat / Tillinghast, Grant / McFaline-Figueroa, José L / Sancak, Yasemin / Stella, Nephi

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Microtubule targeting agents ( ...

    Abstract Microtubule targeting agents (
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.31.555795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome.

    Chuang, Shu-Hui / Westenbroek, Ruth E / Stella, Nephi / Catterall, William A

    Journal of experimental neurology

    2021  Volume 2, Issue 2, Page(s) 81–85

    Abstract: Dravet Syndrome (DS) is a severe childhood epilepsy caused by heterozygous loss-of-function mutations in ... ...

    Abstract Dravet Syndrome (DS) is a severe childhood epilepsy caused by heterozygous loss-of-function mutations in the
    Language English
    Publishing date 2021-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 2692-2819
    ISSN (online) 2692-2819
    DOI 10.33696/neurol.2.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pharmacological Characterization of the Endocannabinoid Sensor GRAB

    Singh, Simar / Sarroza, Dennis / English, Anthony / McGrory, Maya / Dong, Ao / Zweifel, Larry / Land, Benjamin B / Li, Yulong / Bruchas, Michael R / Stella, Nephi

    Cannabis and cannabinoid research

    2023  

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2867624-5
    ISSN 2378-8763 ; 2578-5125
    ISSN (online) 2378-8763
    ISSN 2578-5125
    DOI 10.1089/can.2023.0036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: P2X

    Singh, Simar / Sarroza, Dennis / English, Anthony / Whittington, Dale / Dong, Ao / Malamas, Michael / Makriyannis, Alexandros / van der Stelt, Mario / Li, Yulong / Zweifel, Larry / Bruchas, Michael R / Land, Benjamin B / Stella, Nephi

    British journal of pharmacology

    2024  

    Abstract: Background and purpose: Neurotransmission and neuroinflammation are controlled by local increases in both extracellular ATP and the endocannabinoid 2-arachidonoyl glycerol (2-AG). While it is known that extracellular ATP stimulates 2-AG production in ... ...

    Abstract Background and purpose: Neurotransmission and neuroinflammation are controlled by local increases in both extracellular ATP and the endocannabinoid 2-arachidonoyl glycerol (2-AG). While it is known that extracellular ATP stimulates 2-AG production in cells in culture, the dynamics and molecular mechanisms that underlie this response remain poorly understood. Detection of real-time changes in eCB levels with the genetically encoded sensor, GRAB
    Experimental approach: 2-AG and arachidonoylethanolamide (AEA) levels in Neuro2a (N2a) cells were measured by LC-MS, and GRAB
    Key results: 2-AG and AEA increased GRAB
    Conclusions and implications: Considering that P2X
    Language English
    Publishing date 2024-04-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 80081-8
    ISSN 1476-5381 ; 0007-1188
    ISSN (online) 1476-5381
    ISSN 0007-1188
    DOI 10.1111/bph.16348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Neuroscience. Inflammation to rebuild a brain.

    Stella, Nephi

    Science (New York, N.Y.)

    2012  Volume 338, Issue 6112, Page(s) 1303–1304

    MeSH term(s) Animals ; Brain Injuries/physiopathology ; Encephalitis/physiopathology ; Neural Stem Cells/physiology ; Neurogenesis ; Regeneration ; Zebrafish/physiology
    Language English
    Publishing date 2012-11-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.1232331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB

    Deng, Liting / Viray, Katie / Singh, Simar / Cravatt, Ben / Stella, Nephi

    Cannabis and cannabinoid research

    2021  Volume 7, Issue 2, Page(s) 188–198

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Amphetamine/pharmacology ; Animals ; Arachidonic Acids/pharmacology ; Glycerides/pharmacology ; Hydrolases ; Mice ; Mice, Knockout ; Monoacylglycerol Lipases/genetics ; Receptors, Cannabinoid
    Chemical Substances Arachidonic Acids ; Glycerides ; Receptors, Cannabinoid ; Amphetamine (CK833KGX7E) ; Hydrolases (EC 3.-) ; ABHD6 protein, mouse (EC 3.1.1.23) ; Monoacylglycerol Lipases (EC 3.1.1.23)
    Language English
    Publishing date 2021-10-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2867624-5
    ISSN 2378-8763 ; 2578-5125
    ISSN (online) 2378-8763
    ISSN 2578-5125
    DOI 10.1089/can.2021.0066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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