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Article ; Online: The Relevance of Stress and Trauma to Forensic Psychiatry.

Bourget, Dominique

The journal of the American Academy of Psychiatry and the Law

2017 Volume 45, Issue 2, Page(s) 145–146

MeSH term(s)	Forensic Psychiatry ; Humans ; Psychiatry
Language	English
Publishing date	2017
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	1381489-8
ISSN	1943-3662 ; 0091-634X ; 1093-6793
ISSN (online)	1943-3662
ISSN	0091-634X ; 1093-6793
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Article ; Online: Forensic considerations of substance-induced psychosis.

Bourget, Dominique

The journal of the American Academy of Psychiatry and the Law

2013 Volume 41, Issue 2, Page(s) 168–173

MeSH term(s)	Alcohol Amnestic Disorder/diagnosis ; Alcohol Amnestic Disorder/epidemiology ; Alcohol Amnestic Disorder/psychology ; Canada ; Capgras Syndrome/diagnosis ; Capgras Syndrome/epidemiology ; Capgras Syndrome/psychology ; Comorbidity ; Diagnosis, Differential ; Diagnostic and Statistical Manual of Mental Disorders ; Expert Testimony/legislation & jurisprudence ; Homicide/legislation & jurisprudence ; Homicide/psychology ; Humans ; Insanity Defense ; Intention ; Liability, Legal ; Mental Competency/legislation & jurisprudence ; Psychoses, Substance-Induced/diagnosis ; Psychoses, Substance-Induced/epidemiology ; Psychoses, Substance-Induced/psychology ; Psychotic Disorders/diagnosis ; Psychotic Disorders/epidemiology ; Psychotic Disorders/psychology ; Violence/legislation & jurisprudence ; Violence/psychology
Language	English
Publishing date	2013
Publishing country	United States
Document type	Editorial ; Review
ZDB-ID	1381489-8
ISSN	1943-3662 ; 0091-634X ; 1093-6793
ISSN (online)	1943-3662
ISSN	0091-634X ; 1093-6793
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Article ; Online: Dissociation: Defining the Concept in Criminal Forensic Psychiatry.

Bourget, Dominique / Gagné, Pierre / Wood, Stephen Floyd

The journal of the American Academy of Psychiatry and the Law

2017 Volume 45, Issue 2, Page(s) 147–160

Abstract: Claims of amnesia and dissociative experiences in association with a violent crime are not uncommon. Research has shown that dissociation is a risk factor for violence and is seen most often in crimes of extreme violence. The subject matter is most ... ...

Abstract	Claims of amnesia and dissociative experiences in association with a violent crime are not uncommon. Research has shown that dissociation is a risk factor for violence and is seen most often in crimes of extreme violence. The subject matter is most relevant to forensic psychiatry. Peritraumatic dissociation for instance, with or without a history of dissociative disorder, is quite frequently reported by offenders presenting for a forensic psychiatric examination. Dissociation or dissociative amnesia for serious offenses can have legal repercussions stemming from their relevance to the legal constructs of fitness to stand trial, criminal responsibility, and diminished capacity. The complexity in forensic psychiatric assessments often lies in the difficulty of connecting clinical symptomatology reported by violent offenders to a specific condition included in the Diagnostic and Statistical Manual of Mental Disorders (DSM). This article provides a review of diagnostic considerations with regard to dissociation across the DSM nomenclature, with a focus on the main clinical constructs related to dissociation. Forensic implications are discussed, along with some guides for the forensic evaluator of offenders presenting with dissociation.
Language	English
Publishing date	2017-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	1381489-8
ISSN	1943-3662 ; 0091-634X ; 1093-6793
ISSN (online)	1943-3662
ISSN	0091-634X ; 1093-6793
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Article ; Online: Managing pathologic aggression in people with psychotic disorders.

Bourget, Dominique / Labelle, Alain

Journal of psychiatry & neuroscience : JPN

2012 Volume 37, Issue 2, Page(s) E3–4

MeSH term(s)	Aggression/psychology ; Antipsychotic Agents/therapeutic use ; Clozapine/therapeutic use ; Forensic Psychiatry ; Homicide ; Humans ; Male ; Middle Aged ; Psychotic Disorders/psychology ; Psychotic Disorders/therapy ; Schizophrenia, Paranoid/psychology ; Violence
Chemical Substances	Antipsychotic Agents ; Clozapine (J60AR2IKIC)
Language	English
Publishing date	2012-02-16
Publishing country	Canada
Document type	Case Reports ; Journal Article
ZDB-ID	1077443-9
ISSN	1488-2434 ; 1180-4882
ISSN (online)	1488-2434
ISSN	1180-4882
DOI	10.1503/jpn.110174
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Article ; Online: Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria.

Laroussi, Haifa / Aoudache, Yanis / Robert, Emilie / Libante, Virginie / Thiriet, Louise / Mias-Lucquin, Dominique / Douzi, Badreddine / Roussel, Yvonne / Chauvot de Beauchêne, Isaure / Soler, Nicolas / Leblond-Bourget, Nathalie

Nucleic acids research

2022 Volume 50, Issue 14, Page(s) 8127–8142

Abstract: Integrative and conjugative elements (ICEs) are important drivers of horizontal gene transfer in prokaryotes. They are responsible for antimicrobial resistance spread, a major current health concern. ICEs are initially processed by relaxases that ... ...

Abstract	Integrative and conjugative elements (ICEs) are important drivers of horizontal gene transfer in prokaryotes. They are responsible for antimicrobial resistance spread, a major current health concern. ICEs are initially processed by relaxases that recognize the binding site of oriT sequence and nick at a conserved nic site. The ICESt3/Tn916/ICEBs1 superfamily, which is widespread among Firmicutes, encodes uncanonical relaxases belonging to a recently identified family called MOBT. This family is related to the rolling circle replication initiators of the Rep_trans family. The nic site of these MOBT relaxases is conserved but their DNA binding site is still unknown. Here, we identified the bind site of RelSt3, the MOBT relaxase from ICESt3. Unexpectedly, we found this bind site distantly located from the nic site. We revealed that the binding of the RelSt3 N-terminal HTH domain is required for efficient nicking activity. We also deciphered the role of RelSt3 in the initial and final stages of DNA processing during conjugation. Especially, we demonstrated a strand transfer activity, and the formation of covalent DNA-relaxase intermediate for a MOBT relaxase.
MeSH term(s)	Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Binding Sites ; Conjugation, Genetic ; DNA Nucleotidyltransferases/genetics ; DNA Nucleotidyltransferases/metabolism ; DNA, Bacterial/genetics ; Gene Transfer, Horizontal ; Gram-Positive Bacteria/genetics ; Interspersed Repetitive Sequences ; Plasmids/genetics
Chemical Substances	Bacterial Proteins ; DNA, Bacterial ; DNA Nucleotidyltransferases (EC 2.7.7.-) ; DNA relaxase (EC 2.7.7.-)
Language	English
Publishing date	2022-07-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	186809-3
ISSN	1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
ISSN (online)	1362-4962 ; 1362-4954
ISSN	0301-5610 ; 0305-1048
DOI	10.1093/nar/gkac607
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Article ; Online: Women who kill their mates.

Bourget, Dominique / Gagné, Pierre

Behavioral sciences & the law

2012 Volume 30, Issue 5, Page(s) 598–614

Abstract: Spousal homicide perpetrators are much more likely to be men than women. Accordingly, little research has focused on delineating characteristics of women who have committed spousal homicide. A retrospective clinical review of coroners' files containing ... ...

Abstract	Spousal homicide perpetrators are much more likely to be men than women. Accordingly, little research has focused on delineating characteristics of women who have committed spousal homicide. A retrospective clinical review of coroners' files containing all cases of spousal homicide occurring in Quebec over a 20-year period was carried out. A total of 276 spousal homicides occurred between 1991 and 2010, with 42 homicides by female spouses and 234 homicides by male spouses. Differences between homicides committed by female offenders and male offenders are discussed, and findings on spousal homicide committed by women are compared with those of previous studies. Findings regarding offenses perpetrated by females in the context of mental illness, domestic violence, and homicide-suicide are explored. The finding that only 28% of the female offenders in the Quebec sample had previously been subjected to violence by their victim is in contrast to the popular belief and reports that indicate that most female-perpetrated spousal homicide occurs in self-defense or in reaction to long-term abuse. In fact, women rarely gave a warning before killing their mates. Most did not suffer from a mental illness, although one-fifth were acutely intoxicated at the time of the killing. In the vast majority of cases of women who killed their mates, there were very few indicators that might have signaled the risk and helped predict the violent lethal behavior.
MeSH term(s)	Adult ; Age Factors ; Confidence Intervals ; Female ; Homicide/psychology ; Humans ; Interview, Psychological ; Logistic Models ; Male ; Mental Disorders/epidemiology ; Odds Ratio ; Prisoners/psychology ; Quebec/epidemiology ; Sex Distribution ; Spouses ; Women/psychology ; Young Adult
Language	English
Publishing date	2012-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	232671-1
ISSN	1099-0798 ; 0735-3936
ISSN (online)	1099-0798
ISSN	0735-3936
DOI	10.1002/bsl.2033
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Article: Forensic psychiatry in Canada: a journey on the road to specialty.

Bourget, Dominique / Chaimowitz, Gary

The journal of the American Academy of Psychiatry and the Law

2010 Volume 38, Issue 2, Page(s) 158–162

MeSH term(s)	Academies and Institutes/trends ; Accreditation/trends ; Canada ; Fellowships and Scholarships/trends ; Forecasting ; Forensic Psychiatry/trends ; Humans ; Specialization/trends
Language	English
Publishing date	2010
Publishing country	United States
Document type	Editorial
ZDB-ID	1381489-8
ISSN	1093-6793 ; 0091-634X
ISSN	1093-6793 ; 0091-634X
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Article ; Online: Sexual sadism in sexual offenders and sexually motivated homicide.

Briken, Peer / Bourget, Dominique / Dufour, Mathieu

The Psychiatric clinics of North America

2014 Volume 37, Issue 2, Page(s) 215–230

Abstract: This article gives a clinically oriented overview of forensically relevant forms of sexual sadism disorder and its specific relationship to sexual homicide. In sexual homicide perpetrators, peculiar patterns of sexual sadism may be a motivational pathway ...

Abstract	This article gives a clinically oriented overview of forensically relevant forms of sexual sadism disorder and its specific relationship to sexual homicide. In sexual homicide perpetrators, peculiar patterns of sexual sadism may be a motivational pathway to kill. Sexual sadism increases the risk for reoffending in sexual offenders. Through psychotherapy and pharmacological interventions, treatment of sadistic sex offenders has to consider special characteristics that may be different from those of nonsadistic sex offenders. Many of these offenders share a combination of sexual sadistic motives and an intact self-regulation, sometimes combined with a high level of sexual preoccupation.
MeSH term(s)	Brain Mapping ; Comorbidity ; Diagnostic and Statistical Manual of Mental Disorders ; Disease Management ; Homicide/psychology ; Homicide/statistics & numerical data ; Humans ; Magnetic Resonance Imaging ; Mental Disorders/epidemiology ; Motivation ; Psychiatric Status Rating Scales ; Sadism/diagnosis ; Sadism/epidemiology ; Sadism/physiopathology ; Sex Offenses/psychology ; Sex Offenses/statistics & numerical data
Language	English
Publishing date	2014-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	431518-2
ISSN	1558-3147 ; 0193-953X
ISSN (online)	1558-3147
ISSN	0193-953X
DOI	10.1016/j.psc.2014.03.003
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Article ; Online: Assessment of the paraphilias.

Seto, Michael C / Kingston, Drew A / Bourget, Dominique

The Psychiatric clinics of North America

2014 Volume 37, Issue 2, Page(s) 149–161

Abstract: Paraphilias are recurrent, persistent, and intense sexual interests in atypical objects or activities. The most commonly encountered paraphilias in sexological or forensic settings are pedophilia, sexual sadism, exhibitionism, and voyeurism. Paraphilias ... ...

Abstract	Paraphilias are recurrent, persistent, and intense sexual interests in atypical objects or activities. The most commonly encountered paraphilias in sexological or forensic settings are pedophilia, sexual sadism, exhibitionism, and voyeurism. Paraphilias are often comorbid with other sexual, mood, and personality disorders. Assessment and diagnosis require an integration of multiple sources of clinical information, given the limits and biases of self-report (through clinical interview or questionnaires). Clinicians ideally have access to more objective assessment methods, such as phallometric testing of sexual arousal. The accurate assessment and diagnosis of paraphilias is essential to effective treatment and management.
MeSH term(s)	Adult ; Comorbidity ; Exhibitionism/epidemiology ; Exhibitionism/psychology ; Humans ; Male ; Mental Disorders/epidemiology ; Mental Disorders/psychology ; Observer Variation ; Paraphilic Disorders/diagnosis ; Paraphilic Disorders/epidemiology ; Paraphilic Disorders/psychology ; Paraphilic Disorders/therapy ; Psychiatric Status Rating Scales ; Voyeurism/epidemiology ; Voyeurism/psychology
Language	English
Publishing date	2014-06
Publishing country	United States
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	431518-2
ISSN	1558-3147 ; 0193-953X
ISSN (online)	1558-3147
ISSN	0193-953X
DOI	10.1016/j.psc.2014.03.001
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Article ; Online: Management and clinical outcomes of Lyme disease in acute care facilities in 2 endemic regions of Quebec, Canada: a multicentre retrospective cohort study.

Musonera, Jean B / Valiquette, Louis / Baron, Geneviève / Milord, François / Marcoux, Dominique / Thivierge, Karine / Bedard-Dallaire, Samuel / Pelletier, Andrée A / Lachance, Raphaël / Bourget, Jeremy / Simard, Catherine / Cantin, Emmanuelle / Abbasi, Farhad / Haraoui, Louis-Patrick / Carignan, Alex

CMAJ open

2022 Volume 10, Issue 2, Page(s) E570–E576

Abstract: Background: Despite increases in cases of Lyme disease, little is known about the management and clinical course of the disease in Canada. We aimed to describe the management and clinical course of Lyme disease in patients treated in acute care ... ...

Abstract	Background: Despite increases in cases of Lyme disease, little is known about the management and clinical course of the disease in Canada. We aimed to describe the management and clinical course of Lyme disease in patients treated in acute care facilities in Quebec and to assess adherence to the 2006 Infectious Diseases Society of America (IDSA) guideline. Methods: This retrospective multicentre cohort study included pediatric and adult patients with serologically confirmed Lyme disease treated in acute care facilities (12 community hospitals and 2 tertiary care centres) of 2 endemic regions of Quebec (Estrie and Montérégie), from 2004 to 2017. We considered drug choice, prescribed dose and treatment duration in assessing adherence of prescriptions to the 2006 IDSA guideline. The main outcome was complete resolution of symptoms at 3 months after the initiation of treatment. Results: We included 272 patients from 14 institutions (age range 3-87 yr). Early disseminated Lyme disease (140 patients [51%]) was predominant. Adherence to the IDSA guideline was observed in 235 (90%) of the 261 cases with complete information, and adherence was stable over time (2004-2013: 57/64 [89%]; 2014-2015: 64/71 [90%]; 2016-2017: 114/126 [90%]; Interpretation: We observed clinical resolution of Lyme disease in 99% of the patients, and most treatments (90%) complied with the 2006 IDSA guideline. The incidence of post-treatment Lyme disease syndrome increased over the study period, warranting further prospective studies.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Canada ; Child ; Child, Preschool ; Cohort Studies ; Humans ; Lyme Disease/diagnosis ; Lyme Disease/drug therapy ; Lyme Disease/epidemiology ; Middle Aged ; Post-Lyme Disease Syndrome ; Prospective Studies ; Quebec/epidemiology ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2022-06-28
Publishing country	Canada
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2701622-5
ISSN	2291-0026 ; 2291-0026
ISSN (online)	2291-0026
ISSN	2291-0026
DOI	10.9778/cmajo.20210063
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