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  1. Article ; Online: J

    Castiblanco, Diana P / Norton, Darrell D / Maul, Robert W / Gearhart, Patricia J

    Molecular immunology

    2018  Volume 97, Page(s) 101–108

    Abstract: ... polymerase II accumulation and promote mutagenesis, we deleted 613 bp of DNA downstream of the J ...

    Abstract Activation-induced deaminase (AID) introduces nucleotide substitutions within the variable region of immunoglobulin genes to promote antibody diversity. This activity, which is limited to 1.5 kb downstream of the variable gene promoter, mutates both the coding exon and downstream intronic sequences. We recently reported that RNA polymerase II accumulates in these regions during transcription in mice. This build-up directly correlates with the area that is accessible to AID, and manipulation of RNA polymerase II levels alters the mutation frequency. To address whether the intronic DNA sequence by itself can regulate RNA polymerase II accumulation and promote mutagenesis, we deleted 613 bp of DNA downstream of the J
    MeSH term(s) Animals ; Base Sequence ; Burkitt Lymphoma/genetics ; Burkitt Lymphoma/pathology ; Cell Line, Tumor ; DNA Mutational Analysis ; Genes, Immunoglobulin ; Humans ; Immunoglobulin Variable Region/genetics ; Introns/genetics ; Mice ; Mutagenesis/physiology ; Mutation Rate ; RNA Polymerase II/metabolism ; Somatic Hypermutation, Immunoglobulin/genetics
    Chemical Substances Immunoglobulin Variable Region ; RNA Polymerase II (EC 2.7.7.-)
    Language English
    Publishing date 2018-04-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 424427-8
    ISSN 1872-9142 ; 0161-5890
    ISSN (online) 1872-9142
    ISSN 0161-5890
    DOI 10.1016/j.molimm.2018.03.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 166: Show issues Location:
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  2. Article: A National Department of Health: Professor J. Pease Norton, of Yale University, Department of Social Science, Advocates the Establishment of a Department of Health at Washington as an Administrative Branch of the Government.

    Norton, J Pease

    Buffalo medical journal

    2023  Volume 62, Issue 5, Page(s) 291–292

    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426473-3
    ISSN 1040-3817
    ISSN 1040-3817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    AMP -385/400-: Show issues

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  3. Article ; Online: Redescriptions of North American Epidamaeus (Acari, Oribatida, Damaeidae) species proposed by N. Banks, H.E. Ewing, A.P. Jacot, and J.W. Wilson.

    Norton, Roy A / Ermilov, Sergey G

    Zootaxa

    2021  Volume 5021, Issue 1, Page(s) 1–65

    Abstract: Early American acarologists proposed several species that have been recombined to the oribatid mite genus Epidamaeus (Damaeidae), but none has been redescribed to modern standards. These include E. puritanicus (Banks, 1906), E. michaeli (Ewing, 1909), E. ...

    Abstract Early American acarologists proposed several species that have been recombined to the oribatid mite genus Epidamaeus (Damaeidae), but none has been redescribed to modern standards. These include E. puritanicus (Banks, 1906), E. michaeli (Ewing, 1909), E. globifer (Ewing, 1913), E. florida (Wilson, 1936), E. olitor (Jacot, 1937), and E. craigheadi (Jacot, 1939). We redescribe and illustrate these species, based on available type specimens and other material in various collections, and give an indication of their overall distributions. Juvenile instars are at least partly described for all except E. florida and E. olitor. Since these six collectively include the most encountered Epidamaeus species in the eastern USA, a diagnostic key is presented that also includes E. arcticola (Hammer, 1952), which is reliably recorded from eastern North America (New Hampshire) for the first time. A neotype is selected for E. michaeli, which is considered a senior subjective synonym of E. canadensis (Banks, 1909) [new syn.]. Synonymy of E. puritanicus with E. grandjeani (Bulanova-Zachvatkina, 1957) is rejected.
    MeSH term(s) Animals ; Mites
    Language English
    Publishing date 2021-08-16
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5021.1.1
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  4. Article ; Online: The Importance of Environmental Exposure History in Forecasting Dungeness Crab Megalopae Occurrence Using J-SCOPE, a High-Resolution Model for the US Pacific Northwest

    Emily L. Norton / Samantha Siedlecki / Isaac C. Kaplan / Albert J. Hermann / Jennifer L. Fisher / Cheryl A. Morgan / Suzanna Officer / Casey Saenger / Simone R. Alin / Jan Newton / Nina Bednaršek / Richard A. Feely

    Frontiers in Marine Science, Vol

    2020  Volume 7

    Abstract: ... extracted from JISAO’s Seasonal Coastal Ocean Prediction of the Ecosystem (J-SCOPE), a high-resolution ... coupled physical-biogeochemical model. The analysis included variables from J-SCOPE identified ...

    Abstract The Dungeness crab (Metacarcinus magister) fishery is one of the highest value fisheries in the US Pacific Northwest, but its catch size fluctuates widely across years. Although the underlying causes of this wide variability are not well understood, the abundance of M. magister megalopae has been linked to recruitment into the adult fishery 4 years later. These pelagic megalopae are exposed to a range of ocean conditions during their dispersal period, which may drive their occurrence patterns. Environmental exposure history has been found to be important for some pelagic organisms, so we hypothesized that inclusion of recent environmental exposure history would improve our ability to predict inter-annual variability in M. magister megalopae occurrence patterns compared to using “in situ” conditions alone. We combined 8 years of local observations of M. magister megalopae and regional simulations of ocean conditions to model megalopae occurrence using a generalized linear model (GLM) framework. The modeled ocean conditions were extracted from JISAO’s Seasonal Coastal Ocean Prediction of the Ecosystem (J-SCOPE), a high-resolution coupled physical-biogeochemical model. The analysis included variables from J-SCOPE identified in the literature as important for larval crab occurrence: temperature, salinity, dissolved oxygen concentration, nitrate concentration, phytoplankton concentration, pH, aragonite, and calcite saturation state. GLMs were developed with either in situ ocean conditions or environmental exposure histories generated using particle tracking experiments. We found that inclusion of exposure history improved the ability of the GLMs to predict megalopae occurrence 98% of the time. Of the six swimming behaviors used to simulate megalopae dispersal, five behaviors generated GLMs with superior fits to the observations, so a biological ensemble of these models was constructed. When the biological ensemble was used for forecasting, the model showed skill in predicting megalopae occurrence (AUC = 0.94). Our ...
    Keywords Metacarcinus magister ; megalopae ; particle tracking ; simulated larval behaviors ; exposure history ; habitat modeling ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Subject code 333 ; 551
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Fano resonance in a gold nanosphere with a J-aggregate coating.

    Fales, Andrew M / Norton, Stephen J / Crawford, Bridget M / DeLacy, Brendan G / Vo-Dinh, Tuan

    Physical chemistry chemical physics : PCCP

    2015  Volume 17, Issue 38, Page(s) 24931–24936

    Abstract: We present a facile method to induce J-aggregate formation on gold nanospheres in colloidal ... solution using polyvinylsulfate. The nanoparticle J-aggregate complex results in an absorption spectrum ... and exciton of the J-aggregates. A theoretical simulation of a J-aggregate coated and uncoated gold ...

    Abstract We present a facile method to induce J-aggregate formation on gold nanospheres in colloidal solution using polyvinylsulfate. The nanoparticle J-aggregate complex results in an absorption spectrum with a split lineshape due to plasmon-exciton coupling, i.e. via the formation of upper and lower plexcitonic branches. The use of nanoparticles with different plasmon resonances alters the position of the upper plexcitonic band while the lower band remains at the same wavelength. This splitting is investigated theoretically, and shown analytically to arise from Fano resonance between the plasmon of the gold nanoparticles and exciton of the J-aggregates. A theoretical simulation of a J-aggregate coated and uncoated gold nanosphere produces an absorption spectrum that shows good agreement with the experimentally measured spectra.
    MeSH term(s) Gold/chemistry ; Metal Nanoparticles/chemistry ; Particle Size ; Polyvinyls/chemistry ; Sulfonic Acids/chemistry ; Surface Plasmon Resonance
    Chemical Substances Polyvinyls ; Sulfonic Acids ; lyapolate (26101-52-0) ; Gold (7440-57-5)
    Language English
    Publishing date 2015-10-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/c5cp03277f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Erratum to "The Movius Line sensu lato (Norton et al., 2006) further assessed and defined" J. H. Evol. 55 (2008) 1148-1150.

    Norton, Christopher J / Bae, Kidong

    Journal of human evolution

    2008  Volume 57, Issue 3, Page(s) 331–334

    MeSH term(s) Archaeology ; Far East ; Humans ; Manufactured Materials
    Language English
    Publishing date 2008-12-01
    Publishing country England
    Document type Comment ; News
    ZDB-ID 120141-4
    ISSN 1095-8606 ; 0047-2484
    ISSN (online) 1095-8606
    ISSN 0047-2484
    DOI 10.1016/j.jhevol.2009.03.002
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    Zs.A 976: Show issues Location:
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  7. Article: Bariatric surgery--a successful way to battle the weight crisis (Br J Surg 2006; 93: 259-260).

    Smart, N / Norton, S / Morgan, J

    The British journal of surgery

    2006  Volume 93, Issue 6, Page(s) 769

    MeSH term(s) Gastric Bypass/methods ; Humans ; Obesity, Morbid/surgery
    Language English
    Publishing date 2006-06
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 2985-3
    ISSN 0007-1323 ; 0263-1202 ; 1355-7688
    ISSN 0007-1323 ; 0263-1202 ; 1355-7688
    DOI 10.1002/bjs.5477
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    Uk I Zs.66: Show issues Location:
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  8. Article: Rupture of the Heart.

    Norton, J Howard

    Medical examiner (Philadelphia, Pa.)

    2023  Volume 7, Issue 23, Page(s) 276

    Language English
    Publishing date 2023-12-20
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Treatment of Tetanus.

    Norton, J F

    Buffalo medical and surgical journal

    2023  Volume 2, Issue 1, Page(s) 19–22

    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426472-1
    ISSN 1040-3825
    ISSN 1040-3825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    AMP -365/384-: Show issues

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  10. Article: Tumor in the Lumbar Region.

    Norton, J F

    Buffalo medical and surgical journal

    2023  Volume 2, Issue 5, Page(s) 142–143

    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426472-1
    ISSN 1040-3825
    ISSN 1040-3825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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