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Article ; Online: Variation of M···H-C Interactions in Square-Planar Complexes of Nickel(II), Palladium(II), and Platinum(II) Probed by Luminescence Spectroscopy and X-ray Diffraction at Variable Pressure.

Poirier, Stéphanie / Lynn, Hudson / Reber, Christian / Tailleur, Elodie / Marchivie, Mathieu / Guionneau, Philippe / Probert, Michael R

Inorganic chemistry

2018 Volume 57, Issue 13, Page(s) 7713–7723

Abstract: Luminescence spectra of isoelectronic square-planar ... ...

Abstract	Luminescence spectra of isoelectronic square-planar d
Language	English
Publishing date	2018-07-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	1484438-2
ISSN	1520-510X ; 0020-1669
ISSN (online)	1520-510X
ISSN	0020-1669
DOI	10.1021/acs.inorgchem.8b00724
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A unified filtering method for estimating asymmetric orientation distribution functions.

Poirier, Charles / Descoteaux, Maxime

NeuroImage

2024 Volume 287, Page(s) 120516

Abstract: Numerous filtering methods have been proposed for estimating asymmetric orientation distribution functions (ODFs) for diffusion magnetic resonance imaging (dMRI). It can be hard to make sense of all these different methods, which share similar features ... ...

Abstract	Numerous filtering methods have been proposed for estimating asymmetric orientation distribution functions (ODFs) for diffusion magnetic resonance imaging (dMRI). It can be hard to make sense of all these different methods, which share similar features and result in similar outputs. In this work, we disentangle these many filtering methods proposed in the past and combine them into a novel, unified filtering equation. We also propose a self-supervised data-driven approach for calibrating the filtering parameter values. Our equation is implemented in an open-source GPU-accelerated python software to facilitate its integration into any existing dMRI processing pipeline. Our method is applied on multi-shell multi-tissue fiber ODFs from the Human Connectome Project dataset (1.25 mm
MeSH term(s)	Humans ; Image Processing, Computer-Assisted/methods ; Algorithms ; Brain/diagnostic imaging ; White Matter/diagnostic imaging ; Diffusion Magnetic Resonance Imaging/methods
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1147767-2
ISSN	1095-9572 ; 1053-8119
ISSN (online)	1095-9572
ISSN	1053-8119
DOI	10.1016/j.neuroimage.2024.120516
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Zs.A 3664: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Mechanisms of T cell evasion by Epstein-Barr virus and implications for tumor survival.

Sausen, D G / Poirier, M C / Spiers, L M / Smith, E N

Frontiers in immunology

2023 Volume 14, Page(s) 1289313

Abstract: Epstein-Barr virus (EBV) is a prevalent oncogenic virus estimated to infect greater than 90% of the world's population. Following initial infection, it establishes latency in host B cells. EBV has developed a multitude of techniques to avoid detection by ...

Abstract	Epstein-Barr virus (EBV) is a prevalent oncogenic virus estimated to infect greater than 90% of the world's population. Following initial infection, it establishes latency in host B cells. EBV has developed a multitude of techniques to avoid detection by the host immune system and establish lifelong infection. T cells, as important contributors to cell-mediated immunity, make an attractive target for these immunoevasive strategies. Indeed, EBV has evolved numerous mechanisms to modulate T cell responses. For example, it can augment expression of programmed cell death ligand-1 (PD-L1), which inhibits T cell function, and downregulates the interferon response, which has a strong impact on T cell regulation. It also modulates interleukin secretion and can influence major histocompatibility complex (MHC) expression and presentation. In addition to facilitating persistent EBV infection, these immunoregulatory mechanisms have significant implications for evasion of the immune response by tumor cells. This review dissects the mechanisms through which EBV avoids detection by host T cells and discusses how these mechanisms play into tumor survival. It concludes with an overview of cancer treatments targeting T cells in the setting of EBV-associated malignancy.
MeSH term(s)	Humans ; Herpesvirus 4, Human ; Epstein-Barr Virus Infections ; T-Lymphocytes ; Neoplasms ; B-Lymphocytes/metabolism
Language	English
Publishing date	2023-12-21
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1289313
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Article ; Online: Credible narrators and misinformed readers.

Houghton, Kenneth J / Poirier, Rachel C / Klin, Celia M

Memory & cognition

2022 Volume 51, Issue 4, Page(s) 825–844

Abstract: Stories have a powerful ability to shape our beliefs, attitudes, opinions, and knowledge about the world. In the current work, we ask how readers evaluate the truth of facts embedded in fiction. In three experiments, we investigate the influence of the ... ...

Abstract	Stories have a powerful ability to shape our beliefs, attitudes, opinions, and knowledge about the world. In the current work, we ask how readers evaluate the truth of facts embedded in fiction. In three experiments, we investigate the influence of the credibility of the story's narrator on the likelihood that readers encode and recall misinformation contained in the narrative. Participants read stories containing accurate real-world facts and misleading lures. The stories were narrated by either a credible or a non-credible narrator. Following the stories, participants were tested for the critical story information with a free response test of their general knowledge (Experiments 1 and 2) or with a speeded true-false test (Experiment 3). Overall, narrator credibility had no influence on readers' memory for accurate information. However, readers were more likely to reproduce and affirm misinformation when it was delivered by a credible than a non-credible narrator. The current studies suggest that the credibility and the expertise of the source of the information are critical in determining what readers remember and believe.
MeSH term(s)	Humans ; Mental Recall ; Reading ; Narration ; Communication ; Attitude ; Comprehension/physiology
Language	English
Publishing date	2022-11-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	185691-1
ISSN	1532-5946 ; 0090-502X
ISSN (online)	1532-5946
ISSN	0090-502X
DOI	10.3758/s13421-022-01368-1
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Zs.A 4560: Show issues

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Article ; Online: A LAMP point-of-care test to guide antimicrobial choice for treatment of Staphylococcus pseudintermedius pyoderma in dogs.

Pirolo, M / Menezes, M / Poulsen, M / Søndergaard, V / Damborg, P / Poirier, A C / La Ragione, R / Schjærff, M / Guardabassi, L

Veterinary journal (London, England : 1997)

2024 Volume 304, Page(s) 106105

Abstract: Staphylococcus pseudintermedius is the most common cause of pyoderma in dogs. We validated a point-of-care (PoC) test based on colorimetric loop-mediated isothermal amplification (LAMP) for rapid S. pseudintermedius identification and susceptibility ... ...

Abstract	Staphylococcus pseudintermedius is the most common cause of pyoderma in dogs. We validated a point-of-care (PoC) test based on colorimetric loop-mediated isothermal amplification (LAMP) for rapid S. pseudintermedius identification and susceptibility testing for first line antimicrobials for systemic treatment of canine pyoderma, i.e., lincosamides, first generation cephalosporins and amoxicillin clavulanate. Newly designed LAMP primers targeting clinically relevant resistance genes were combined with a previously validated set of primers targeting spsL for species identification. After laboratory validation on 110 clinical isolates, we assessed the performance of the test on 101 clinical specimens using routine culture and susceptibility testing as a reference standard. The average hands-on and turnaround times for the PoC test were 30 and 90 min, respectively. The assay showed sensitivity and specificity near 100% for both species identification and susceptibility testing when performed on bacterial cultures or clinical specimens in the laboratory. However, the PoC test yielded less accurate results when performed on-site by clinical staff (92% sensitivity and 64% specificity for species identification, 67% sensitivity and 96% specificity for β-lactam susceptibility, and 83% sensitivity and 71% specificity for lincosamide susceptibility). These results indicate that the PoC test should be adapted to a user-friendly technology to facilitate performance and interpretation of results by clinical staff. If properly developed, the test would allow veterinarians to gain rapid information on antimicrobial choice, limiting the risk of treatment failure and facilitating adherence to antimicrobial use guidelines in small animal veterinary dermatology.
MeSH term(s)	Dogs ; Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Staphylococcus ; Pyoderma/drug therapy ; Pyoderma/veterinary ; Pyoderma/microbiology ; Anti-Infective Agents/therapeutic use ; Microbial Sensitivity Tests/veterinary ; Dog Diseases/drug therapy ; Dog Diseases/microbiology ; Staphylococcal Infections/veterinary
Chemical Substances	Anti-Bacterial Agents ; Anti-Infective Agents
Language	English
Publishing date	2024-03-26
Publishing country	England
Document type	Journal Article
ZDB-ID	428614-5
ISSN	1532-2971 ; 0372-5545 ; 1090-0233
ISSN (online)	1532-2971
ISSN	0372-5545 ; 1090-0233
DOI	10.1016/j.tvjl.2024.106105
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Article ; Online: Choanoflagellates alongside diverse uncultured predatory protists consume the abundant open-ocean cyanobacterium

Wilken, Susanne / Yung, Charmaine C M / Poirier, Camille / Massana, Ramon / Jimenez, Valeria / Worden, Alexandra Z

Proceedings of the National Academy of Sciences of the United States of America

2023 Volume 120, Issue 27, Page(s) e2302388120

Abstract: ... ...

Abstract	Prochlorococcus
MeSH term(s)	Choanoflagellata ; Prochlorococcus/genetics ; Bacteria ; Dinoflagellida ; Oceans and Seas ; Seawater/microbiology
Language	English
Publishing date	2023-06-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2302388120
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Article ; Online: Standardized direct oral anticoagulants prescription for treatment of acute venous thromboembolism in the emergency department: A quality improvement initiative.

Simard, C / Poirier-Blanchette, L / Rizzolo, A / Cafaro, T / Kerzner, R / Mantzanis, H / Koolian, M

Thrombosis research

2024 Volume 236, Page(s) 68–73

Abstract: Introduction: Direct oral anticoagulants (DOACs) are commonly used for the treatment and prevention of venous thromboembolism (VTE). However, prescription errors with DOACs can lead to patient dissatisfaction and harm. This study aimed to evaluate the ... ...

Abstract	Introduction: Direct oral anticoagulants (DOACs) are commonly used for the treatment and prevention of venous thromboembolism (VTE). However, prescription errors with DOACs can lead to patient dissatisfaction and harm. This study aimed to evaluate the impact of a standardized prescription for DOACs for VTE on prescription appropriateness. Materials and methods: The study included patients discharged from the Emergency Department (ED) with a DOAC prescription for an acute VTE. A standardized prescription tool was developed and implemented, and patients were divided into pre- and post-intervention groups. The appropriateness of prescriptions was assessed using the Medication Appropriateness Index (MAI). Results: A total of 161 patients with VTE were included in the study. The post-intervention group showed a significant increase in prescriptions with an MAI rating of "appropriate" and a decrease in ratings of "inappropriate." Improvements were observed in loading dose duration, maintenance dose frequency and duration, and inclusion of necessary drug coverage codes. Conclusion: The implementation of a standardized prescription for DOACs in the management of VTE in the ED significantly improved medication appropriateness and reduced inappropriate prescriptions. Standardized prescriptions have the potential to enhance patient safety and optimize care by providing clear and uniform guidance to healthcare providers. Further research is needed to explore the effectiveness of medication prescription software systems in real-world clinical settings to improve prescribing practices.
MeSH term(s)	Humans ; Anticoagulants/therapeutic use ; Venous Thromboembolism/drug therapy ; Quality Improvement ; Administration, Oral ; Venous Thrombosis/drug therapy ; Prescriptions ; Emergency Service, Hospital
Chemical Substances	Anticoagulants
Language	English
Publishing date	2024-02-16
Publishing country	United States
Document type	Letter
ZDB-ID	121852-9
ISSN	1879-2472 ; 0049-3848
ISSN (online)	1879-2472
ISSN	0049-3848
DOI	10.1016/j.thromres.2024.02.015
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Article ; Online: Remembering Radim J. Šrám.

DeMarini, David M / Poirier, Miriam C / Waters, Michael D / Holland, Nina

Environmental and molecular mutagenesis

2023 Volume 64, Issue 2, Page(s) 70–71

Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	639145-x
ISSN	1098-2280 ; 0893-6692
ISSN (online)	1098-2280
ISSN	0893-6692
DOI	10.1002/em.22528
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Article ; Online: Federal food assistance accessibility and acceptability among Indigenous Peoples in the United States: A scoping review.

Estradé, Michelle / Bode, Bree / Walls, Melissa / Lewis, Emma C / Poirier, Lisa / Sundermeir, Samantha M / Gittelsohn, Joel

The Journal of nutrition

2024

Abstract: The purpose of this scoping review was to determine the extent to which accessibility and acceptability of federal food assistance programs in the United States (U.S.) have been evaluated among Indigenous Peoples, and to summarize what is currently known. ...

Abstract	The purpose of this scoping review was to determine the extent to which accessibility and acceptability of federal food assistance programs in the United States (U.S.) have been evaluated among Indigenous Peoples, and to summarize what is currently known. Twelve publications were found that examine aspects of accessibility or acceptability by indigenous peoples of one or more federal food assistance programs, including the Supplemental Nutrition Assistance Program (SNAP) and/or the Food Distribution Program on Indian Reservations (FDPIR) (n=8), the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) (n=3), and the National School Lunch Program (NSLP) (n=1). No publications were found to include the Commodity Supplemental Food Program (CSFP) or the Child and Adult Care Food Program (CACFP). Publications ranged in time from 1990 - 2023, and all reported on findings from rural populations, while three also included urban settings. Program accessibility varied by program type and geographic location. Road conditions, transportation access, telephone and internet connectivity, and overall number of food stores were identified as key access barriers to SNAP and WIC benefit redemption in rural areas. Program acceptability was attributed to factors such as being tribally administered, providing culturally sensitive services, and offering foods of cultural significance. For these reasons, FDPIR and WIC were more frequently described as acceptable compared to SNAP and NSLP. However, SNAP was occasionally described as more acceptable than other assistance programs because it allows participants autonomy to decide which foods to purchase and when. Overall, little attention has been paid to the accessibility and acceptability of federal food assistance programs among Indigenous Peoples in the U.S. More research is needed to understand and improve the participation experiences and health trajectories of these priority populations.
Language	English
Publishing date	2024-04-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.1016/j.tjnut.2024.04.017
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Article ; Online: A Single-Center 18-Year Series of 73 Cases of Metaplastic Carcinoma of the Breast.

Thériault, Kassandra / Ben Moussa, Mariem / Perron, Marjorie / Desbiens, Christine / Poirier, Brigitte / Poirier, Éric / Leblanc, Dominique / Morin, Claudya / Lemieux, Julie / Hogue, Jean-Charles / Boudreau, Dominique

The breast journal

2024 Volume 2024, Page(s) 5920505

Abstract: Aim: To examine the clinical management of metaplastic breast cancer (MeBC), particularly the role of chemotherapy.: Methods: This retrospective study included patients with MeBC (: Results: The median follow-up was 57.2 months. The mean tumor ... ...

Abstract	Aim: To examine the clinical management of metaplastic breast cancer (MeBC), particularly the role of chemotherapy. Methods: This retrospective study included patients with MeBC ( Results: The median follow-up was 57.2 months. The mean tumor size was 39.5 ± 32.1 (range, 1-200) mm. Most were in grade 3 (75.3%), without evidence of clinical nodal involvement (75.3%), and triple-negative (79.5%). Chemotherapy was given to 49 (67.1%) patients. Thirty-seven patients (50.7%) underwent a mastectomy, and 22/37 (59.5%) received radiotherapy. Adjuvant chemotherapy was given to 36 patients (49.3%), and nine (12.3%) patients were treated with neoadjuvant chemotherapy. The 5-year OS and DFS rates were 60.2% and 66.8%. Among the nine patients who received neoadjuvant chemotherapy, three (33.3%) achieved a partial response, three (33.3%) had stable disease, and three (33.3%) had disease progression. The use of chemotherapy, especially in the adjuvant setting, had a significant positive effect on 5-year OS ( Conclusion: MeBC represents a rare heterogeneous group of malignancies with poor prognosis. Adjuvant chemotherapy was associated with improved OS and DFS. Patients should be carefully selected for neoadjuvant chemotherapy.
MeSH term(s)	Humans ; Female ; Breast Neoplasms/pathology ; Mastectomy ; Retrospective Studies ; Radiotherapy, Adjuvant ; Disease-Free Survival ; Chemotherapy, Adjuvant ; Carcinoma/surgery ; Neoadjuvant Therapy ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Prognosis
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1289960-4
ISSN	1524-4741 ; 1075-122X
ISSN (online)	1524-4741
ISSN	1075-122X
DOI	10.1155/2024/5920505
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