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  1. Article ; Online: Changes in the prevalence of infectious diseases before and after the COVID-19 pandemic in Pakistan.

    Rana, Muhammad Suleman / Usman, Muhammad / Alam, Muhammad Masroor / Tahir, Muhammad / Ikram, Aamer / Zaidi, Syed Sohail Zahoor / Kashif, Muqarrab / Massab, Umair / Faryal, Rani / Anas, Muhammad / Ullah, Nadeem / Salman, Muhammad

    The Journal of infection

    2023  Volume 86, Issue 4, Page(s) 415–416

    MeSH term(s) Humans ; COVID-19/epidemiology ; Pakistan/epidemiology ; Prevalence ; Pandemics ; Communicable Diseases/epidemiology
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2023.01.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Inositol Supplementation in the Prevention of Gestational Diabetes Mellitus.

    Tahir, Faryal / Majid, Zainab

    Cureus

    2019  Volume 11, Issue 9, Page(s) e5671

    Abstract: Inositol, an emerging novel therapy for the treatment of gestational diabetes mellitus (GDM), is a cyclic polyol that has insulin-like effects and plays an important role in glucose homeostasis. The conventional treatment of GDM with insulin and oral ... ...

    Abstract Inositol, an emerging novel therapy for the treatment of gestational diabetes mellitus (GDM), is a cyclic polyol that has insulin-like effects and plays an important role in glucose homeostasis. The conventional treatment of GDM with insulin and oral antihyperglycemic drugs usually comes with side effects, paving the way for and shedding spotlight on clinical trials involving inositol. This review analyzed a host of recent trials that involved inositol supplementation for preventing GDM and their positive outcomes in reducing the rate of GDM among obese and overweight pregnant women, as well as women with polycystic ovarian syndrome (PCOS) or a family history of type 2 diabetes mellitus.
    Language English
    Publishing date 2019-09-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.5671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Chronic Traumatic Encephalopathy; a mere concern for athletes or single blow victims equally vulnerable?

    Majid, Bushra / Majid, Zainab / Tahir, Faryal

    JPMA. The Journal of the Pakistan Medical Association

    2019  Volume 69, Issue 11, Page(s) 1762

    MeSH term(s) Athletes ; Brain Concussion ; Chronic Traumatic Encephalopathy ; Humans ; Motion Pictures ; Physicians
    Language English
    Publishing date 2019-11-18
    Publishing country Pakistan
    Document type Journal Article ; Comment
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.5455/JPMA.36521.
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Post-splenectomy Sepsis: A Review of the Literature.

    Tahir, Faryal / Ahmed, Jawad / Malik, Farheen

    Cureus

    2020  Volume 12, Issue 2, Page(s) e6898

    Abstract: The spleen is an intraperitoneal organ that performs vital hematological and immunological functions. It maintains both innate and adaptive immunity and protects the body from microbial infections. The removal of the spleen as a treatment method was ... ...

    Abstract The spleen is an intraperitoneal organ that performs vital hematological and immunological functions. It maintains both innate and adaptive immunity and protects the body from microbial infections. The removal of the spleen as a treatment method was initiated from the early 1500s for traumatic injuries, even before the physiology of spleen was properly understood. Splenectomy has therapeutic effects in many conditions such as sickle cell anemia, thalassemia, idiopathic thrombocytopenic purpura (ITP), Hodgkin's disease, and lymphoma. However, it increases the risk of infections and, in some cases, can lead to a case of severe sepsis known as overwhelming post-splenectomy infection (OPSI), which has a very high mortality rate. Encapsulated bacteria form a major proportion of the invading organisms, of which the most common is
    Language English
    Publishing date 2020-02-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.6898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Long-standing Sporadic Pancreatic Insulinoma: Report of a Rare Case.

    Majid, Zainab / Tahir, Faryal / Haider, Syed Ali

    Cureus

    2020  Volume 12, Issue 2, Page(s) e6947

    Abstract: Insulinomas are rare, functional pancreatic neuroendocrine tumors arising from the pancreatic multipotent stem cells or neuroendocrine islet, occurring with a higher proportion in females. Majority of insulinomas have a sporadic etiology; however, only 5% ...

    Abstract Insulinomas are rare, functional pancreatic neuroendocrine tumors arising from the pancreatic multipotent stem cells or neuroendocrine islet, occurring with a higher proportion in females. Majority of insulinomas have a sporadic etiology; however, only 5%-10% develop as a part of multiple endocrine neoplasm type 1 syndrome. They usually present with symptoms of hypoglycemia including disturbance in orientation, tremors, diaphoresis, altered mental state, seizures and visual changes among others. The diagnosis is based on appreciation of the classic Whipple triad, i.e. neuroglycopenic symptoms and sympathetic drive along with low serum glucose levels (<50 mg/dL) and a complete reversibility of these symptoms with prompt administration of glucose. The gold standard treatment for insulinoma involves complete surgical excision (i.e. enucleation), which is curative in 90% of the patients. Health care physicians should have a high index of suspicion for this tumor in patients presenting with neurological and sympathetic symptoms, particularly if they are resolved after eating. Here, we report the case of a 48-year-old female with the history of multiple episodes of hypoglycemic symptoms for the past two years which improved on glucose intake. Furthermore, we also summarized the discussion regarding diagnosis and management of pancreatic insulinoma.
    Language English
    Publishing date 2020-02-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.6947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Phenotype versus genotype discordant rifampicin susceptibility testing in tuberculosis: implications for a diagnostic accuracy.

    Qadir, Mehmood / Faryal, Rani / Khan, Muhammad Tahir / Khan, Sajjad Ahmed / Zhang, Shulin / Li, Weimin / Wei, Dong Qing / Tahseen, Sabira / McHugh, Timothy D

    Microbiology spectrum

    2023  Volume 12, Issue 1, Page(s) e0163123

    Abstract: Importance: An accurate diagnosis of drug resistance in clinical isolates is an important step for better treatment outcomes. The current study observed a higher discordance rate of rifampicin resistance on Mycobacteria Growth Indicator Tube (MGIT) drug ...

    Abstract Importance: An accurate diagnosis of drug resistance in clinical isolates is an important step for better treatment outcomes. The current study observed a higher discordance rate of rifampicin resistance on Mycobacteria Growth Indicator Tube (MGIT) drug susceptibility testing (DST) than Lowenstein-Jenson (LJ) DST when compared with the
    MeSH term(s) Humans ; Rifampin/pharmacology ; Rifampin/therapeutic use ; Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Mycobacterium tuberculosis/genetics ; Microbial Sensitivity Tests ; Tuberculosis/diagnosis ; Tuberculosis/drug therapy ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/microbiology ; Genotype ; Phenotype
    Chemical Substances Rifampin (VJT6J7R4TR) ; Antitubercular Agents
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01631-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Anti-tuberculous Effects of Statin Therapy: A Review of Literature.

    Tahir, Faryal / Bin Arif, Taha / Ahmed, Jawad / Shah, Syed Raza / Khalid, Muhammad

    Cureus

    2020  Volume 12, Issue 3, Page(s) e7404

    Abstract: Tuberculosis (TB) is a chronic infection caused ... ...

    Abstract Tuberculosis (TB) is a chronic infection caused by
    Language English
    Publishing date 2020-03-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7404
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Zinc deficiency: An independent risk factor for high blood pressure.

    Tahir, Faryal / Majid, Zainab / Qadar, Laila Tul

    JPMA. The Journal of the Pakistan Medical Association

    2019  Volume 69, Issue 10, Page(s) 1578

    MeSH term(s) Biological Availability ; Deficiency Diseases/metabolism ; Deficiency Diseases/prevention & control ; Humans ; Hypertension/metabolism ; Hypertension/prevention & control ; Nutritional Requirements ; Renal Reabsorption/physiology ; Risk Factors ; Zinc/deficiency ; Zinc/metabolism
    Chemical Substances Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2019-10-17
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Acute Myocardial Infarction as an Initial Presentation of Protein C and Protein S Deficiency Followed by Dilated Cardiomyopathy in a Young Male.

    Tahir, Faryal / Majid, Zainab / Majid, Bushra / Khan, Sherbano

    Cureus

    2019  Volume 11, Issue 4, Page(s) e4492

    Abstract: Protein C and protein S are vitamin K dependent anti-coagulant proteins required for the inhibition of activated protein V and VIII. In an inherited thrombophilia, hypercoagulability caused by the deficiency of protein C and protein S predisposes an ... ...

    Abstract Protein C and protein S are vitamin K dependent anti-coagulant proteins required for the inhibition of activated protein V and VIII. In an inherited thrombophilia, hypercoagulability caused by the deficiency of protein C and protein S predisposes an individual to increased risk of thromboembolism (TE) that could herald as a venous thromboemboilsm (VTE) in the leg, pulmonary embolism (PE), stroke, or Budd-Chiari syndrome. However, very rarely does inherited thrombophilia cause coronary artery thrombosis leading to the development of myocardial infarction (MI). We report a case of a young male with combined protein C and protein S deficiency who presented with acute MI, worsened ventricular systolic function, and progressive declination of ejection fraction (EF) secondary to dilated cardiomyopathy (DCM).
    Language English
    Publishing date 2019-04-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.4492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Chylomicron Retention Disease in A Male Infant: A Rare Case from Pakistan.

    Kumar, Sohail / Nanjiani, Deedar / Tahir, Faryal / Azim, Dua / Parkash, Oam

    Cureus

    2020  Volume 12, Issue 3, Page(s) e7184

    Abstract: Chylomicron retention disease (CMRD), also known as Anderson's disease, is an autosomal recessive condition with a genetic mutation in the secretion associated Ras related GTPase 1B (SAR1B) gene, a protein coding gene. CMRD classically manifests as ... ...

    Abstract Chylomicron retention disease (CMRD), also known as Anderson's disease, is an autosomal recessive condition with a genetic mutation in the secretion associated Ras related GTPase 1B (SAR1B) gene, a protein coding gene. CMRD classically manifests as steatorrhea, vomiting, failure to thrive or abdominal bloating shortly after birth or in childhood. Here, we report a rare case of a 50-day-old male infant who was, at first, overseen as a case of acute gastroenteritis with sepsis owing to the non-specific symptoms i.e. multiple episodes of loose stools with a low-grade fever and failure to thrive, and was managed accordingly. However, the symptoms did not resolve; moreover, the clinical condition deteriorated. Later, lipid profile, clinical presentation and pathological features led to a presumptive diagnosis of CMRD. Our patient showed significant improvement when treated with a trial of medium- and short-chain fatty acids. We conclude that, in resource-restricted countries, a therapeutic trial with the dietary changes is essential to not only prevent the devastating complication but also support the diagnosis.
    Language English
    Publishing date 2020-03-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.7184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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