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  1. Book: Natriuretic peptides

    Clerico, Aldo

    the hormones of the heart

    2006  

    Author's details Aldo Clerico ... (ed.)
    Language English
    Size XIV, 184 S : Ill., graph. Darst.
    Publisher Springer
    Publishing place Milan u.a.
    Publishing country Italy
    Document type Book
    HBZ-ID HT014795846
    ISBN 88-470-0497-7 ; 978-88-470-0497-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2006 A 3935 order for loan Magazin

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  2. Article ; Online: Rapid rule-in and rule-out protocols of acute myocardial infarction using hs-cTnI and hs-cTnT methods.

    Clerico, Aldo / Zaninotto, Martina / Plebani, Mario

    Clinical chemistry and laboratory medicine

    2023  Volume 62, Issue 2, Page(s) 213–217

    MeSH term(s) Humans ; Myocardial Infarction/diagnosis ; Biomarkers ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2023-09-25
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-1010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Book ; Online: Natriuretic Peptides

    Clerico, Aldo / Emdin, Michele

    The Hormones of the Heart

    2006  

    Author's details edited by Aldo Clerico, Michele Emdin
    Keywords Cardiology ; Endocrinology ; Pathology
    Language English
    Publisher Springer-Verlag Italia
    Publishing place Milano
    Document type Book ; Online
    HBZ-ID TT050387944
    ISBN 978-88-470-0497-9 ; 978-88-470-0498-6 ; 88-470-0497-7 ; 88-470-0498-5
    DOI 10.1007/88-470-0498-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Cardiovascular risk evaluation in pregnancy: focus on cardiac specific biomarkers.

    Aldo, Clerico / Martina, Zaninotto / Alberto, Aimo / Mario, Plebani

    Clinical chemistry and laboratory medicine

    2023  Volume 62, Issue 4, Page(s) 581–592

    Abstract: Despite the evidence demonstrating the clinical utility of cardiac specific biomarkers in improving cardiovascular risk evaluation in several clinical conditions, even the most recent reviews and guidelines fail to consider their measurement in order to ... ...

    Abstract Despite the evidence demonstrating the clinical utility of cardiac specific biomarkers in improving cardiovascular risk evaluation in several clinical conditions, even the most recent reviews and guidelines fail to consider their measurement in order to enhance the accuracy of the evaluation of cardiovascular risk in pregnant women. The aim of this review article was to examine whether the assay of cardiac specific biomarkers can enhance cardiovascular risk evaluation in pregnant women, first by reviewing the relationships between the physiological state of pregnancy and cardiac specific biomarkers. The clinical relevance of brain natriuretic peptide (BNP)/NT-proBNP and high-sensitivity cardiac troponin I/high-sensitivity cardiac troponin T (hs-cTnI/hs-cTnT) assay in improving cardiovascular risk evaluation is examined based on the results of clinical studies on subjects with normal and those with complicated pregnancy. Finally, the analytical approaches and clinical objectives related to cardio specific biomarkers are advocated in order to allow an early and more accurate evaluation of cardiovascular risk in pregnant women.
    MeSH term(s) Pregnancy ; Humans ; Female ; Cardiovascular Diseases/diagnosis ; Risk Factors ; Heart ; Troponin T ; Biomarkers ; Heart Disease Risk Factors ; Natriuretic Peptide, Brain ; Peptide Fragments
    Chemical Substances Troponin T ; Biomarkers ; Natriuretic Peptide, Brain (114471-18-0) ; Peptide Fragments
    Language English
    Publishing date 2023-11-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2023-0609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Transdermal measurement of cardiac troponins: the future is now.

    Clerico, Aldo / Aimo, Alberto / Zaninotto, Martina / Plebani, Mario

    Clinical chemistry and laboratory medicine

    2022  Volume 60, Issue 8, Page(s) 1133–1135

    MeSH term(s) Biomarkers ; Humans ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2022-05-05
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2022-0382
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: High-sensitivity assay for cardiac troponins with POCT methods. The future is soon.

    Clerico, Aldo / Zaninotto, Martina / Plebani, Mario

    Clinical chemistry and laboratory medicine

    2021  Volume 59, Issue 9, Page(s) 1477–1478

    MeSH term(s) Biomarkers ; Humans ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2021-06-07
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2021-0620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Inflammageing and Cardiovascular System

    Marco Alfonso Perrone / Alberto Aimo / Sergio Bernardini / Aldo Clerico

    International Journal of Molecular Sciences, Vol 24, Iss 1, p

    Focus on Cardiokines and Cardiac-Specific Biomarkers

    2023  Volume 844

    Abstract: The term “inflammageing” was introduced in 2000, with the aim of describing the chronic inflammatory state typical of elderly individuals, which is characterized by a combination of elevated levels of inflammatory biomarkers, a high burden of ... ...

    Abstract The term “inflammageing” was introduced in 2000, with the aim of describing the chronic inflammatory state typical of elderly individuals, which is characterized by a combination of elevated levels of inflammatory biomarkers, a high burden of comorbidities, an elevated risk of disability, frailty, and premature death. Inflammageing is a hallmark of various cardiovascular diseases, including atherosclerosis, hypertension, and rapid progression to heart failure. The great experimental and clinical evidence accumulated in recent years has clearly demonstrated that early detection and counteraction of inflammageing is a promising strategy not only to prevent cardiovascular disease, but also to slow down the progressive decline of health that occurs with ageing. It is conceivable that beneficial effects of counteracting inflammageing should be most effective if implemented in the early stages, when the compensatory capacity of the organism is not completely exhausted. Early interventions and treatments require early diagnosis using reliable and cost-effective biomarkers. Indeed, recent clinical studies have demonstrated that cardiac-specific biomarkers (i.e., cardiac natriuretic peptides and cardiac troponins) are able to identify, even in the general population, the individuals at highest risk of progression to heart failure. However, further clinical studies are needed to better understand the usefulness and cost/benefit ratio of cardiac-specific biomarkers as potential targets in preventive and therapeutic strategies for early detection and counteraction of inflammageing mechanisms and in this way slowing the progressive decline of health that occurs with ageing.
    Keywords ageing ; inflammation ; cardiovascular risk ; cardiac natriuretic peptides ; cardiac troponins ; myocardial injury ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The pathophysiological and clinical relevance of combined measurement of natriuretic peptides and cardiac troponins for risk prediction of incident heart failure in community-dwelling individuals.

    Clerico, Aldo / Aimo, Alberto / Passino, Claudio

    European journal of heart failure

    2021  Volume 23, Issue 3, Page(s) 403–405

    MeSH term(s) Heart Failure ; Humans ; Independent Living ; Natriuretic Peptide, Brain ; Natriuretic Peptides ; Troponin
    Chemical Substances Natriuretic Peptides ; Troponin ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2021-02-11
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.2112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5299: Show issues Location:
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  9. Article ; Online: Measurement of Cardiac-Specific Biomarkers in the Emergency Department: New Insight in Risk Evaluation.

    Aspromonte, Nadia / Zaninotto, Martina / Aimo, Alberto / Fumarulo, Isabella / Plebani, Mario / Clerico, Aldo

    International journal of molecular sciences

    2023  Volume 24, Issue 21

    Abstract: The aim of this article review is to analyze some models and clinical issues related to the implementation of accelerated diagnostic protocols based on specific cardiac biomarkers in patients admitted to the emergency department (ED) with symptoms ... ...

    Abstract The aim of this article review is to analyze some models and clinical issues related to the implementation of accelerated diagnostic protocols based on specific cardiac biomarkers in patients admitted to the emergency department (ED) with symptoms compatible with acute cardiac disorders. Four specific clinical issues will be discussed in detail: (a) pathophysiological and clinical interpretations of circulating hs-cTnI and hs-cTnT levels; (b) the clinical relevance and estimation of the biological variation of biomarkers in patients admitted to the ED with acute and severe diseases; (c) the role and advantages of the point-of-care testing (POCT) methods for cardiac-specific biomarkers in pre-hospital and hospital clinical practice; and (d) the clinical role of specific cardiac biomarkers in patients with acute heart failure (AHF). In order to balance the risk between a hasty discharge versus the potential harms caused by a cardiac assessment in patients admitted to the ED with suspected acute cardiovascular disease, the measurement of specific cardiac biomarkers is essential for the early identification of the presence of myocardial dysfunction and/or injury and to significantly reduce the length and costs of hospitalization. Moreover, specific cardiac biomarkers (especially hs-cTnI and hs-cTnT) are useful predictors of mortality and major adverse cardiovascular events (MACE) in patients admitted to the ED with suspected acute cardiovascular disease. To guide the implementation of the most rapid algorithms for the diagnosis of Non-ST-Elevation Myocardial Infarction (NSTEMI) into routine clinical practice, clinical scientific societies and laboratory medicine societies should promote collaborative studies specifically designed for the evaluation of the analytical performance and, especially, the cost/benefit ratio resulting from the use of these clinical protocols and POCT methods in the ED clinical practice.
    MeSH term(s) Humans ; Myocardial Infarction/diagnosis ; Troponin T ; Troponin I ; Emergency Service, Hospital ; Biomarkers
    Chemical Substances Troponin T ; Troponin I ; Biomarkers
    Language English
    Publishing date 2023-11-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242115998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Diagnostic algorithms for non-ST-segment elevation myocardial infarction: open issues.

    Clerico, Aldo / Aimo, Alberto / Zaninotto, Martina / Plebani, Mario

    Clinical chemistry and laboratory medicine

    2021  Volume 59, Issue 11, Page(s) 1761–1771

    Abstract: The use of serial measurement of cardiac troponin (cTn) is recommended by international guidelines for the diagnosis of myocardial infarction (MI) since 2000. This article focuses on factors influencing temporal changes in high-sensitive cTn (hs)-cTn and ...

    Abstract The use of serial measurement of cardiac troponin (cTn) is recommended by international guidelines for the diagnosis of myocardial infarction (MI) since 2000. This article focuses on factors influencing temporal changes in high-sensitive cTn (hs)-cTn and the impact of these factors on the diagnosis of non-ST-segment elevation MI (NSTEMI). The recommendations proposed by three different international guidelines published in 2020-2021 for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation (NSTE) show some discrepancies. In particular, there is no agreement among these guidelines about cut-off or absolute change values to be used for the rule-in, especially regarding the use of sex-specific cut-off values. Furthermore, there are no sufficient evidences on the diagnostic accuracy and cost effectiveness related to cut-off values suggested for algorithms to be used by some hs-cTnI methods.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Algorithms ; Biomarkers ; Female ; Humans ; Male ; Myocardial Infarction/diagnosis ; Non-ST Elevated Myocardial Infarction/diagnosis ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2021-07-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2021-0550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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