Article ; Online: Fisiopatología del shock séptico.
Medicina intensiva
2024 Volume 46 Suppl 1, Page(s) 1–13
Abstract: Sepsis and septic shock result from an inadequate host response to an infection, which causes organ dysfunction. The progression of this condition is manifested by the occurrence of successive clinical stages, resulting from the systemic inflammatory ... ...
| Title translation | Pathophysiology of septic shock. |
|---|---|
| Abstract | Sepsis and septic shock result from an inadequate host response to an infection, which causes organ dysfunction. The progression of this condition is manifested by the occurrence of successive clinical stages, resulting from the systemic inflammatory response secondary to the activation of different inflammatory mediators, leading to organ dysfunction. There is a high burden of evidence on the role of endotoxin in the pathogenesis of sepsis and its crucial role in triggering the inflammatory response in sepsis caused by gram-negative bacteria. The coagulation cascade activation in sepsis patients is part of the host's adaptive immune response to infection. The endothelium is the main target in sepsis, which is metabolically active and can. |
| Language | Spanish |
| Publishing date | 2024-01-04 |
| Publishing country | Spain |
| Document type | English Abstract ; Journal Article |
| ISSN | 2173-5727 |
| ISSN (online) | 2173-5727 |
| DOI | 10.1016/j.medine.2022.03.010 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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