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Article ; Online: Neuromyelitis optica in a 9 year old girl

Soutrik Seth

Asian Journal of Medical Sciences, Vol 7, Iss 5, Pp 132-

A case report

2016 Volume 134

Abstract: Neuromyelitis optica (NMO) is an acquired demyelinating disorder affecting the optic nerves and spinal cord either simultaneously or sequentially. Prognosis is guarded particularly for the optic neuritis.We report here a case of first attack of NMO ... ...

Abstract	Neuromyelitis optica (NMO) is an acquired demyelinating disorder affecting the optic nerves and spinal cord either simultaneously or sequentially. Prognosis is guarded particularly for the optic neuritis.We report here a case of first attack of NMO occurring in a 9 year old girl child coming from a rural area of Burdwan.
Keywords	demyelinating disorder ; optic neuritis ; neuromyelitis optica ; Medicine ; R
Language	English
Publishing date	2016-08-01T00:00:00Z
Publisher	Manipal College of Medical Sciences, Pokhara
Document type	Article ; Online
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Article ; Online: Clinical Features and Adverse Prognostic Indicators in Datura Poisoning in Children.

Islam, Kamirul / Khatun, Nazima / Seth, Soutrik / Datta, Asok Kumar

Indian pediatrics

2022 Volume 59, Issue 8, Page(s) 652–653

Abstract: We describe the clinical features and adverse prognostic indicators of Datura intoxication in 47 children. 15 (31.9%) children required intensive care and 1 (2.1%) died. Time elapsed >3.15 hour between ingestion and starting treatment [RR (95% CI): 9.4 ( ... ...

Abstract	We describe the clinical features and adverse prognostic indicators of Datura intoxication in 47 children. 15 (31.9%) children required intensive care and 1 (2.1%) died. Time elapsed >3.15 hour between ingestion and starting treatment [RR (95% CI): 9.4 (3.1-28.3)], age <9.5 year [RR (95% CI): 3.5 (1.5-8.0)], and seizure [RR (95% CI): 2.8 (1.4-5.8)] were the most important adverse prognostic features.
MeSH term(s)	Child ; Datura ; Humans ; Poisoning ; Prognosis
Language	English
Publishing date	2022-08-12
Publishing country	India
Document type	Journal Article
ZDB-ID	402594-5
ISSN	0974-7559 ; 0019-6061
ISSN (online)	0974-7559
ISSN	0019-6061
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Article ; Online: Predictors of Renal Complications in Children With Hematotoxic Snakebite.

Islam, Kamirul / Seth, Soutrik / Roy, Atanu / Datta, Asok Kumar

Indian pediatrics

2020 Volume 57, Issue 5, Page(s) 427–430

Abstract: Objective: To study the predictors of renal complications following hematotoxic snakebite in children.: Methods: This comparative study was conducted in the pediatric ward of a tertiary-care centre among 364 consecutively children admitted with ... ...

Abstract	Objective: To study the predictors of renal complications following hematotoxic snakebite in children. Methods: This comparative study was conducted in the pediatric ward of a tertiary-care centre among 364 consecutively children admitted with hematotoxic snakebite between January 2016 and December 2017. Clinical and laboratory indicators were compared between children who developed acute kidney injury and those who did not. Results: Acute kidney injury was seen in 139 children (38.2%), majority being stage 2 (55, 39.5%). 59 children (16.2%) developed permanent renal damage and 16 (4.4%) died due to envenomation. Acute tubular necrosis was the most common (25, 39.1%) histopathological change. Conclusions: Receiving anti-snake venom more than one hour after bite was the most significant adverse prognostic indicator, both for renal complications and mortality.
Language	English
Publishing date	2020-05-19
Publishing country	India
Document type	Journal Article
ZDB-ID	402594-5
ISSN	0974-7559 ; 0019-6061
ISSN (online)	0974-7559
ISSN	0019-6061
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Article ; Online: Nasal HFOV versus nasal IPPV as a post-extubation respiratory support in preterm infants-a randomised controlled trial.

Seth, Soutrik / Saha, Bijan / Saha, Anindya Kumar / Mukherjee, Suchandra / Hazra, Avijit

European journal of pediatrics

2021 Volume 180, Issue 10, Page(s) 3151–3160

Abstract: Early and successful extubation prevents several morbidities in preterm newborns. Several secondary non-invasive respiratory modalities exist but with their merits and demerits. Given the benefits of nasal high-frequency oscillatory ventilation (nHFOV), ... ...

Abstract	Early and successful extubation prevents several morbidities in preterm newborns. Several secondary non-invasive respiratory modalities exist but with their merits and demerits. Given the benefits of nasal high-frequency oscillatory ventilation (nHFOV), we tried to examine whether nHFOV could reduce reintubation rates compared to nasal intermittent positive pressure ventilation (NIPPV) during the post-extubation phase in preterm infants. Stratified randomisation based on gestational age was done for 86 mechanically ventilated preterm infants between 26 and 36
MeSH term(s)	Airway Extubation ; Child, Preschool ; Continuous Positive Airway Pressure ; Gestational Age ; High-Frequency Ventilation ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Intermittent Positive-Pressure Ventilation ; Respiratory Distress Syndrome, Newborn/therapy
Language	English
Publishing date	2021-04-23
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-021-04084-1
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Article: A study on the prevalence and correlates of nicotine dependence among adolescents of Burdwan Town, West Bengal.

Islam, Kamirul / Datta, Asok Kumar / Seth, Soutrik / Roy, Atanu / Das, Rajib

Indian journal of psychiatry

2019 Volume 61, Issue 1, Page(s) 89–93

Abstract: Context: Tobacco will cause one billion deaths in the 21: Aims: To find out the level of nicotine dependence and it correlates among adolescents.: Settings and design: A community-based, cross-sectional, observational study was conducted in the ... ...

Abstract	Context: Tobacco will cause one billion deaths in the 21 Aims: To find out the level of nicotine dependence and it correlates among adolescents. Settings and design: A community-based, cross-sectional, observational study was conducted in the Burdwan town, West Bengal, among 1354 adolescent tobacco users. Materials and methods: Data were collected by direct interview using a pretested, predesigned, semistructured schedule containing the Fagerström Test for Nicotine Dependence (FTND) questionnaire. Statistical analysis: Pearson's Chi-square test, Student's unpaired Results: The mean FTND score was significantly higher among adolescents aged >15 years, males, Hindu, tobacco users from joint family, who belonged to lower socioeconomic status, who started using tobacco at the age of 10-12 years, using tobacco for ≥5 years, who were not married, were illiterate, working, and not aware of the injurious effect of tobacco to health. Conclusions: A suitable individualized approach should be used for those who want to quit tobacco depending on their FTND score.
Language	English
Publishing date	2019-02-11
Publishing country	India
Document type	Journal Article
ZDB-ID	221523-8
ISSN	0019-5545
ISSN	0019-5545
DOI	10.4103/psychiatry.IndianJPsychiatry_112_18
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Article ; Online: Comparison of STOPS and SNAPPE-II in Predicting Neonatal Survival at Hospital Discharge: A Prospective, Multicentric, Observational Study.

Vardhelli, Venkateshwarlu / Seth, Soutrik / Mohammed, Yassar Arafat / Murki, Srinivas / Tandur, Baswaraj / Saha, Bijan / Oleti, Tejo Pratap / Deshabhotla, Saikiran / Siramshetty, Sunayana / Kallem, Venkat Reddy

Indian journal of pediatrics

2022 Volume 90, Issue 8, Page(s) 781–786

Abstract: Objective: To compare SNAPPE-II and STOPS admission severity scores in neonates admitted to neonatal intensive care unit (NICU) with a gestational age of ≥ 33 wk.: Methods: In this multicenter, prospective, observational study, the sickness scoring ... ...

Abstract	Objective: To compare SNAPPE-II and STOPS admission severity scores in neonates admitted to neonatal intensive care unit (NICU) with a gestational age of ≥ 33 wk. Methods: In this multicenter, prospective, observational study, the sickness scoring was done on all the neonates at 12 h after admission to the NICUs. The scoring systems were compared by the area under the curve (AUC) on the receiver operating characteristics (ROC) curve. Results: A total of 669 neonates with gestational age ≥ 33 wk (mortality rate: 2.4%), who were admitted to five participating NICUs within 24 h of birth, were included. Both SNAPPE-II and STOPS had the good discriminatory and predictive ability for mortality with AUCs of 0.965 [95% confidence interval (CI): 0.94-0.98] and 0.92 (95% CI: 0.87-0.99), respectively. The STOPS scoring system with a cutoff score ≥ 4 on the ROC curve had 85% accuracy, whereas the SNAPPE-II cutoff score ≥ 33 on the ROC curve had 94% accuracy in predicting mortality. Conclusion: In infants with the gestational age of ≥ 33 wk, SNAPPE-II and STOPS showed similar predictive ability, but the STOPS score, being a simpler clinical tool, might be more useful in resource-limited settings.
MeSH term(s)	Infant, Newborn ; Infant ; Humans ; Prospective Studies ; Patient Discharge ; Severity of Illness Index ; Gestational Age ; Intensive Care Units, Neonatal ; ROC Curve ; Hospitals
Language	English
Publishing date	2022-09-22
Publishing country	India
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	218231-2
ISSN	0973-7693 ; 0019-5456
ISSN (online)	0973-7693
ISSN	0019-5456
DOI	10.1007/s12098-022-04330-w
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Article ; Online: Comparison of CRIB-II with SNAPPE-II for predicting survival and morbidities before hospital discharge in neonates with gestation ≤ 32 weeks: a prospective multicentric observational study.

Vardhelli, Venkateshwarlu / Murki, Srinivas / Tandur, Baswaraj / Saha, Bijan / Oleti, Tejo Pratap / Deshabhotla, Saikiran / Mohammed, Yassar Arafat / Seth, Soutrik / Siramshetty, Sunayana / Kallem, Venkat Reddy

European journal of pediatrics

2022 Volume 181, Issue 7, Page(s) 2831–2838

Abstract: Various studies validated and compared Score for Neonatal Acute Physiology with Perinatal extension-II (SNAPPE-II) and Clinical Risk Index for Babies-II (CRIB-II) admission sickness severity scores for predicting survival, but very few studies compared ... ...

Abstract	Various studies validated and compared Score for Neonatal Acute Physiology with Perinatal extension-II (SNAPPE-II) and Clinical Risk Index for Babies-II (CRIB-II) admission sickness severity scores for predicting survival, but very few studies compared them for predicting the morbidities in preterm infants. In this multicenter prospective observational study, SNAPPE-II and CRIB-II newborn illness severity scores were compared for predicting mortality and morbidities in infants with gestational age of ≤ 32 weeks. Major morbidities were classified as bronchopulmonary dysplasia, abnormal cranial ultrasound (presence of intraventricular hemorrhage grade III or more or periventricular leukomalacia grade II to IV), and retinopathy of prematurity requiring treatment. Combined adverse outcome was defined as death or any major morbidity. Comparison of the scoring systems was done by area under the curve (AUC) on receiver operating characteristics curve (ROC curve) analysis. A total of 419 neonates who were admitted to 5 participating NICUs were studied. The mortality rate in the study population was 8.8%. Both CRIB-II (AUC: 0.795) and SNAPPE-II (AUC: 0.78) had good predictive ability for in-hospital mortality. For predicting any one of the major morbidities and combined adverse outcome, CRIB-II had better predictive ability than SNAPPE-II with AUC of 0.83 vs. 0.70 and 0.85 vs. 0.74, respectively. Conclusion: In infants with gestational age of ≤ 32 weeks, both CRIB-II and SNAPPE-II are good scoring systems for predicting mortality. CRIB-II, being a simpler scoring system and having better predictive ability for major morbidities and combined adverse outcome, is preferable over SNAPPE-II. What is known: • SNAPPE-II and CRIB-II scores have good predictive ability on in-hospital mortality in preterm neonates. What is new: • SNAPPE-II and CRIB-II both have good predictive ability for mortality, but CRIB-II has better ability for short-term morbidities related to the prematurity.
MeSH term(s)	Female ; Gestational Age ; Hospitals ; Humans ; Infant ; Infant, Newborn ; Infant, Newborn, Diseases ; Infant, Premature ; Infant, Premature, Diseases ; Infant, Very Low Birth Weight ; Morbidity ; Patient Discharge ; Pregnancy ; Prospective Studies ; Severity of Illness Index
Language	English
Publishing date	2022-05-06
Publishing country	Germany
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-022-04463-2
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Article: A study on association of iron deficiency with attention deficit hyperactivity disorder in a tertiary care center.

Islam, Kamirul / Seth, Soutrik / Saha, Suman / Roy, Atanu / Das, Rajib / Datta, Asok Kumar

Indian journal of psychiatry

2018 Volume 60, Issue 1, Page(s) 131–134

Abstract: Background: Iron is important for brain development and cognitive function. Iron deficiency may cause alteration of neurotransmitters and may be manifested by different central nervous system disorders including attention deficit hyperactivity disorder ( ...

Abstract	Background: Iron is important for brain development and cognitive function. Iron deficiency may cause alteration of neurotransmitters and may be manifested by different central nervous system disorders including attention deficit hyperactivity disorder (ADHD). Aims: As studies are scarce in the Indian context, we had undertaken this study to find out the association between iron deficiency and ADHD. Settings and design: Hospital-based cross-sectional study. Materials and methods: Hematological parameters indicating iron status (hemoglobin [Hb], ferritin, Iron, total iron binding capacity [TIBC], mean corpuscular volume [MCV], and mean corpuscular Hb [MCH]) were measured among 119 ADHD patients selected by complete enumeration method and 119 controls. Statistical analysis: Shapiro-Wilk test, Mann-Whitney U-test, Spearman's correlation, and binary logistic regression were used. Results: Hb, iron, ferritin, MCV, and MCH were lower among cases and negatively correlated to ADHD, while reverse is true for TIBC and ADHD. Iron deficiency anemia makes one 3.82 times more prone for ADHD. Conclusion: Iron deficiency was associated with ADHD.
Language	English
Publishing date	2018-04-30
Publishing country	India
Document type	Journal Article
ZDB-ID	221523-8
ISSN	0019-5545
ISSN	0019-5545
DOI	10.4103/psychiatry.IndianJPsychiatry_197_17
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Article: Cardiofaciocutaneous Syndrome: Case Report of a Rare Disorder.

Seth, Soutrik / Biswas, Tanmoy / Biswas, Biswajit / Roy, Atanu / Datta, Asok Kumar

Journal of clinical and diagnostic research : JCDR

2016 Volume 10, Issue 11, Page(s) SD01–SD02

Abstract: Cardiofaciocutaneous syndrome or CFC syndrome is a rare genetic disorder first described in 1986. It is one of the RASopathies involving multiple organs particularly the heart, skin and face affecting males and females equally. The phenotypic features ... ...

Abstract	Cardiofaciocutaneous syndrome or CFC syndrome is a rare genetic disorder first described in 1986. It is one of the RASopathies involving multiple organs particularly the heart, skin and face affecting males and females equally. The phenotypic features overlap with 2 other conditions, the Noonan and Costello syndrome. We report on a 22-month-old boy with CFC syndrome presenting with typical craniofacial appearance, heart defects, ectodermal abnormalities, growth failure and developmental delay. Estimated population of affected individuals worldwide is a few hundreds.
Language	English
Publishing date	2016-11-01
Publishing country	India
Document type	Case Reports
ZDB-ID	2775283-5
ISSN	0973-709X ; 2249-782X
ISSN (online)	0973-709X
ISSN	2249-782X
DOI	10.7860/JCDR/2016/21586.8811
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Article ; Online: Cardiofaciocutaneous Syndrome

Soutrik Seth / Tanmoy Biswas / Biswajit Biswas / Atanu Roy / Asok Kumar Datta

Journal of Clinical and Diagnostic Research, Vol 10, Iss 11, Pp SD01-SD

Case Report of a Rare Disorder

2016 Volume 02

Abstract	Cardiofaciocutaneous syndrome or CFC syndrome is a rare genetic disorder first described in 1986. It is one of the RASopathies involving multiple organs particularly the heart, skin and face affecting males and females equally. The phenotypic features overlap with 2 other conditions, the Noonan and Costello syndrome. We report on a 22-month-old boy with CFC syndrome presenting with typical craniofacial appearance, heart defects, ectodermal abnormalities, growth failure and developmental delay. Estimated population of affected individuals worldwide is a few hundreds.
Keywords	costello syndrome ; noonan syndrome ; rasopathies ; Medicine ; R
Language	English
Publishing date	2016-11-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
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