LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 22

Search options

  1. Article ; Online: Distinct dorsal and ventral streams for binocular rivalry dominance and suppression revealed by magnetoencephalography.

    Bock, Elizabeth A / Fesi, Jeremy D / Da Silva Castenheira, Jason / Baillet, Sylvain / Mendola, Janine D

    The European journal of neuroscience

    2023  Volume 57, Issue 8, Page(s) 1317–1334

    Abstract: Binocular rivalry is an example of bistable visual perception extensively examined in neuroimaging. Magnetoencephalography can track brain responses to phasic visual stimulations of predetermined frequency and phase to advance our understanding of ... ...

    Abstract Binocular rivalry is an example of bistable visual perception extensively examined in neuroimaging. Magnetoencephalography can track brain responses to phasic visual stimulations of predetermined frequency and phase to advance our understanding of perceptual dominance and suppression in binocular rivalry. We used left and right eye stimuli that flickered at two tagging frequencies to track their respective oscillatory cortical evoked responses. We computed time-resolved measures of coherence to track brain responses phase locked with stimulus frequencies and with respect to the participants' indications of alternations of visual rivalry they experienced. We compared the brain maps obtained to those from a non-rivalrous control replay condition that used physically changing stimuli to mimic rivalry. We found stronger coherence within a posterior cortical network of visual areas during rivalry dominance compared with rivalry suppression and replay control. This network extended beyond the primary visual cortex to several retinotopic visual areas. Moreover, network coherence with dominant percepts in primary visual cortex peaked at least 50 ms prior to the suppressed percept nadir, consistent with the escape theory of alternations. Individual alternation rates were correlated with the rate of change in dominant evoked peaks, but not for the slope of response to suppressed percepts. Effective connectivity measures revealed that dominant (respectively, suppressed) percepts were expressed in dorsal (respectively ventral) streams. We thus demonstrate that binocular rivalry dominance and suppression engage distinct mechanisms and brain networks. These findings advance neural models of rivalry and may relate to more general aspects of selection and suppression in natural vision.
    MeSH term(s) Humans ; Vision, Binocular/physiology ; Magnetoencephalography ; Visual Perception/physiology ; Brain ; Brain Mapping ; Photic Stimulation ; Vision Disparity
    Language English
    Publishing date 2023-03-17
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 645180-9
    ISSN 1460-9568 ; 0953-816X
    ISSN (online) 1460-9568
    ISSN 0953-816X
    DOI 10.1111/ejn.15955
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Cardiorenal syndrome: new perspectives.

    Bock, Jeremy S / Gottlieb, Stephen S

    Circulation

    2010  Volume 121, Issue 23, Page(s) 2592–2600

    MeSH term(s) Heart Failure/complications ; Heart Failure/epidemiology ; Heart Failure/therapy ; Humans ; Kidney Diseases/complications ; Kidney Diseases/epidemiology ; Kidney Diseases/therapy ; Syndrome
    Language English
    Publishing date 2010-06-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.109.886473
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Blunt cardiac injury.

    Bock, Jeremy S / Benitez, R Michael

    Cardiology clinics

    2012  Volume 30, Issue 4, Page(s) 545–555

    Abstract: Blunt chest trauma represents a spectrum of injuries to the heart and aorta that vary markedly in character and severity. The setting, signs, and symptoms of chest trauma are often nonspecific, which represents a challenge to emergency providers. ... ...

    Abstract Blunt chest trauma represents a spectrum of injuries to the heart and aorta that vary markedly in character and severity. The setting, signs, and symptoms of chest trauma are often nonspecific, which represents a challenge to emergency providers. Individuals with suspected blunt chest trauma who have only mild or no symptoms, a normal electrocardiogram (ECG), and are hemodynamically stable typically have a benign course and rarely require further diagnostic testing or long periods of close observation. Individuals with pain, ECG abnormalities, or hemodynamic instability may require rapid evaluation of the heart by echocardiography and the great vessels by advanced imaging.
    MeSH term(s) Aorta/injuries ; Aortic Rupture/diagnosis ; Aortic Rupture/etiology ; Aortic Rupture/therapy ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/etiology ; Arrhythmias, Cardiac/therapy ; Commotio Cordis/diagnosis ; Commotio Cordis/etiology ; Commotio Cordis/therapy ; Contusions/diagnosis ; Contusions/etiology ; Contusions/therapy ; Echocardiography ; Electrocardiography ; Heart Injuries/complications ; Heart Injuries/diagnosis ; Heart Injuries/therapy ; Heart Valves/injuries ; Humans ; Myocardial Infarction/diagnosis ; Myocardial Infarction/etiology ; Myocardial Infarction/therapy ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/therapy
    Language English
    Publishing date 2012-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1196385-2
    ISSN 1558-2264 ; 0733-8651
    ISSN (online) 1558-2264
    ISSN 0733-8651
    DOI 10.1016/j.ccl.2012.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Comparing Physician and Patient Perspectives on Prophylactic Treatment with BAY 94-9027 for Severe Haemophilia A: A Post Hoc Analysis.

    Lalezari, Shadan / Acquadro, Michaël / de Bock, Elodie / Lambert, Jérémy / Simpson, Mindy L

    Advances in therapy

    2020  Volume 37, Issue 6, Page(s) 2763–2776

    Abstract: Introduction: BAY 94-9027 is a newly developed extended half-life product to treat haemophilia, allowing for fewer injections than with standard products. This post hoc analysis aimed to compare physicians' and patients' opinions on BAY 94-9027 ... ...

    Abstract Introduction: BAY 94-9027 is a newly developed extended half-life product to treat haemophilia, allowing for fewer injections than with standard products. This post hoc analysis aimed to compare physicians' and patients' opinions on BAY 94-9027 prophylaxis, and explore how qualitative interview data is aligned with the data from the Haemophilia-specific Quality of Life questionnaire for Adults (Haemo-QoL-A).
    Methods: Exploratory qualitative interviews were conducted with physicians and patients by phone upon the exit of patients from the PROTECT VIII extension phase following a semi-directed guide. In this post hoc analysis, all transcripts were reviewed and reported concepts were compared to assess the level of concordance between physicians and patients. These qualitative data were compared with the Haemo-QoL-A mean global and subscale scores at baseline and end of main phase (36 weeks later).
    Results: Ten physicians and 16 patients (mean age 47 years) from Israel, the Netherlands and the USA were interviewed. Significant improvements were reported by all physicians from baseline [e.g. lower frequency of bleeds (80%), improvement in emotional functioning (90%)], which is in concordance with patients' reports. The improved confidence reported by physicians cascaded to greater participation in various activities, resulting in a better perceived emotional state and a significant improvement on the Haemo-QoL-A emotional impact subscale score (p = 0.04) between baseline and end of main phase. Most physicians (80%) reported improvement in bleed frequency, as patients did (88%). Improvement in physical functioning or mobility was not consistently reported in this 8-month study.
    Conclusion: Interviewed physicians and patients generally agreed on the beneficial impact of BAY 94-9027, specifically regarding the increased level of self-confidence in patients and its subsequent positive impact on patients' lives. These findings supported the observed improvement on the Haemo-QoL-A emotional impact subscale. Overall, this study highlights the concordance between physician and patient perspective on the positive experience with BAY 94-9027.
    MeSH term(s) Adult ; Aged ; Attitude of Health Personnel ; Coagulants/therapeutic use ; Factor VIII/therapeutic use ; Female ; Hemophilia A/drug therapy ; Hemorrhage/drug therapy ; Humans ; Israel ; Male ; Middle Aged ; Netherlands ; Patient Satisfaction/statistics & numerical data ; Physicians/psychology ; Polyethylene Glycols/therapeutic use ; Quality of Life/psychology ; Surveys and Questionnaires ; United States
    Chemical Substances Coagulants ; Polyethylene Glycols (3WJQ0SDW1A) ; Factor VIII (9001-27-8)
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632651-1
    ISSN 1865-8652 ; 0741-238X
    ISSN (online) 1865-8652
    ISSN 0741-238X
    DOI 10.1007/s12325-020-01374-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Creating ultimate customer loyalty through loyalty conviction and customer-company identification

    Wolter, Jeremy S / Bock, Dora / Cronin, J. J / Smith, Jeffery S

    Journal of retailing Vol. 93, No. 4 , p. 458-476

    2017  Volume 93, Issue 4, Page(s) 458–476

    Author's details Jeremy S. Wolter, Dora Bock, Jeffery S. Smith, J. Joseph Cronin Jr
    Keywords Customer-company identification ; Satisfaction ; Loyalty ; Conviction ; Uncertainty ; JUMP model
    Language English
    Publisher Elsevier
    Publishing place New York, NY [u.a.]
    Document type Article
    ZDB-ID 410802-4 ; 2013905-6
    ISSN 0022-4359
    ISSN 0022-4359
    Database ECONomics Information System

    More links

    Kategorien

  6. Article ; Online: Tagged MEG measures binocular rivalry in a cortical network that predicts alternation rate.

    Bock, Elizabeth A / Fesi, Jeremy D / Baillet, Sylvain / Mendola, Janine D

    PloS one

    2019  Volume 14, Issue 7, Page(s) e0218529

    Abstract: Binocular rivalry (BR) is a dynamic visual illusion that provides insight into the cortical mechanisms of visual awareness, stimulus selection, and object identification. When dissimilar binocular images cannot be fused, perception switches every few ... ...

    Abstract Binocular rivalry (BR) is a dynamic visual illusion that provides insight into the cortical mechanisms of visual awareness, stimulus selection, and object identification. When dissimilar binocular images cannot be fused, perception switches every few seconds between the left and right eye images. The speed at which individuals switch between alternatives is a stable, partially heritable trait. In order to isolate the monocular and binocular processes that determine the speed of rivalry, we presented stimuli tagged with a different flicker frequency in each eye and applied stimulus-phase locked MEG source imaging. We hypothesized that the strength of the evoked fundamental or intermodulation frequencies would vary when comparing Fast and Slow Switchers. Ten subjects reported perceptual alternations, with mean dominance durations between 1.2-4.0 sec. During BR, event-related monocular input in V1, and broadly in higher-tier ventral temporal cortex, waxed and waned with the periods of left or right eye dominance/suppression. In addition, we show that Slow Switchers produce greater evoked intermodulation frequency responses in a cortical network composed of V1, lateral occipital, posterior STS, retrosplenial & superior parietal cortices. Importantly, these dominance durations were not predictable from the brain responses to either of the fundamental tagging frequencies in isolation, nor from any responses to a pattern rivalry control condition, or a non-rivalrous control. The novel cortical network isolated, which overlaps with the default-mode network, may contain neurons that compute the level of endogenous monocular difference, and monitor accumulation of this conflict over extended periods of time. These findings are the first to relate the speed of rivalry across observers to the 'efficient coding' theory of computing binocular differences that may apply to binocular vision generally.
    MeSH term(s) Adult ; Cerebral Cortex/physiology ; Female ; Humans ; Male ; Models, Neurological ; Nerve Net/physiology ; Photic Stimulation ; Vision, Binocular/physiology ; Vision, Monocular/physiology
    Language English
    Publishing date 2019-07-11
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0218529
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: A prickly situation.

    Bock, Jeremy S / Riedel, David J / Davis, Charles E

    The American journal of medicine

    2008  Volume 121, Issue 3, Page(s) 199–200

    MeSH term(s) Aneurysm, False/diagnosis ; Aneurysm, False/etiology ; Aneurysm, False/pathology ; Aneurysm, False/surgery ; Anti-Bacterial Agents/therapeutic use ; Endocarditis, Bacterial/drug therapy ; Foreign Bodies/complications ; HIV Infections/complications ; Hepatitis C/complications ; Humans ; Male ; Middle Aged ; Nafcillin/therapeutic use ; Needles ; Substance Abuse, Intravenous/complications
    Chemical Substances Anti-Bacterial Agents ; Nafcillin (4CNZ27M7RV)
    Language English
    Publishing date 2008-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2007.10.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Effect of Iris Color on the Outcome of Descemet Membrane Endothelial Keratoplasty.

    Hayashi, Takahiko / Hos, Deniz / Schrittenlocher, Silvia / Siebelmann, Sebastian / Matthaei, Mario / Franklin, Jeremy / Clahsen, Thomas / Bock, Felix / Bachmann, Björn / Cursiefen, Claus

    Cornea

    2020  Volume 39, Issue 7, Page(s) 846–850

    Abstract: Purpose: To explore the impact of iris color on the outcome of Descemet membrane endothelial keratoplasty (DMEK).: Methods: Consecutive cases of Fuchs endothelial dystrophy after DMEK were retrospectively analyzed from the prospective Cologne DMEK ... ...

    Abstract Purpose: To explore the impact of iris color on the outcome of Descemet membrane endothelial keratoplasty (DMEK).
    Methods: Consecutive cases of Fuchs endothelial dystrophy after DMEK were retrospectively analyzed from the prospective Cologne DMEK database between 2011 and 2017 at the University of Cologne, Germany. Iris pictures were graded by color into blue, green, or brown and compared regarding outcome parameters including best-corrected visual acuity (converted to logarithm of the minimal angle of resolution), central corneal thickness, endothelial cell density (ECD), each at preoperative (baseline) and postoperative 12 months, rebubbling rates, cystoid macular edema (CME), and immune rejections after surgery.
    Results: One thousand one hundred six eyes of 814 patients were included in this study that consisted of 354 blue eyes, 418 green eyes, and 244 brown eyes. There was no significant correlation between iris color and any parameter (best corrected visual acuity; P = 0.064 at preoperatively, P = 0.959 at 12 months) (ECD; P = 0.158 preoperatively, P = 0.859 at 12 months) (central corneal thickness; P = 0.148 preoperatively, P = 0.252 at 12 months). The loss of ECD at 12 months after surgery was 37.2% ± 1.0% in blue eyes, 37.2% ± 0.9% in green eyes, and 37.2% ± 1.2% in brown eyes (P = 0.999). Immune rejections were 1.7%, 2.9%, and 0.8% (P = 0.168) in blue, green, and brown eyes, respectively. Rebubbling rates and CME incidence were similar in each group (P = 0.129, and P = 0.552 respectively).
    Conclusions: The iris color has no significant impact on the outcome after DMEK. Thus, DMEK can be applied effectively, regardless of the iris color.
    MeSH term(s) Aged ; Descemet Stripping Endothelial Keratoplasty/methods ; Eye Color/physiology ; Female ; Follow-Up Studies ; Fuchs' Endothelial Dystrophy/diagnosis ; Fuchs' Endothelial Dystrophy/surgery ; Humans ; Iris/diagnostic imaging ; Male ; Postoperative Period ; Prospective Studies
    Language English
    Publishing date 2020-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604826-2
    ISSN 1536-4798 ; 0277-3740
    ISSN (online) 1536-4798
    ISSN 0277-3740
    DOI 10.1097/ICO.0000000000002305
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Co-catalytic absorption layers for controlled laser-induced chemical vapor deposition of carbon nanotubes.

    Michaelis, F Benjamin / Weatherup, Robert S / Bayer, Bernhard C / Bock, Maximilian C D / Sugime, Hisashi / Caneva, Sabina / Robertson, John / Baumberg, Jeremy J / Hofmann, Stephan

    ACS applied materials & interfaces

    2014  Volume 6, Issue 6, Page(s) 4025–4032

    Abstract: The concept of co-catalytic layer structures for controlled laser-induced chemical vapor deposition of carbon nanotubes is established, in which a thin Ta support layer chemically aids the initial Fe catalyst reduction. This enables a significant ... ...

    Abstract The concept of co-catalytic layer structures for controlled laser-induced chemical vapor deposition of carbon nanotubes is established, in which a thin Ta support layer chemically aids the initial Fe catalyst reduction. This enables a significant reduction in laser power, preventing detrimental positive optical feedback and allowing improved growth control. Systematic study of experimental parameters combined with simple thermostatic modeling establishes general guidelines for the effective design of such catalyst/absorption layer combinations. Local growth of vertically aligned carbon nanotube forests directly on flexible polyimide substrates is demonstrated, opening up new routes for nanodevice design and fabrication.
    Language English
    Publishing date 2014-03-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/am405460r
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Co-catalytic Absorption Layers for Controlled Laser-Induced Chemical Vapor Deposition of Carbon Nanotubes

    Michaelis, F. Benjamin / Baumberg Jeremy J / Bayer Bernhard C / Bock Maximilian C. D / Caneva Sabina / Hofmann Stephan / Robertson John / Sugime Hisashi / Weatherup Robert S

    ACS Applied Materials & Interfaces. 2014 Mar. 26, v. 6, no. 6

    2014  

    Abstract: The concept of co-catalytic layer structures for controlled laser-induced chemical vapor deposition of carbon nanotubes is established, in which a thin Ta support layer chemically aids the initial Fe catalyst reduction. This enables a significant ... ...

    Abstract The concept of co-catalytic layer structures for controlled laser-induced chemical vapor deposition of carbon nanotubes is established, in which a thin Ta support layer chemically aids the initial Fe catalyst reduction. This enables a significant reduction in laser power, preventing detrimental positive optical feedback and allowing improved growth control. Systematic study of experimental parameters combined with simple thermostatic modeling establishes general guidelines for the effective design of such catalyst/absorption layer combinations. Local growth of vertically aligned carbon nanotube forests directly on flexible polyimide substrates is demonstrated, opening up new routes for nanodevice design and fabrication.
    Keywords absorption ; carbon nanotubes ; catalysts ; guidelines ; iron ; models ; vapors
    Language English
    Dates of publication 2014-0326
    Size p. 4025-4032.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021%2Fam405460r
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top