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  1. Article ; Online: Valves, Vegetations, and Valves.

    Judson, Gregory L / Mahadevan, Vaikom S

    The Journal of invasive cardiology

    2022  Volume 34, Issue 7, Page(s) E580

    Abstract: We present a novel method for the treatment of right-sided bioprosthetic valve endocarditis with AngioVac debulking followed by percutaneous pulmonic and tricuspid valve replacement for residual transcatheter valve degeneration and right ventricular ... ...

    Abstract We present a novel method for the treatment of right-sided bioprosthetic valve endocarditis with AngioVac debulking followed by percutaneous pulmonic and tricuspid valve replacement for residual transcatheter valve degeneration and right ventricular dysfunction.
    MeSH term(s) Bioprosthesis/adverse effects ; Endocarditis/diagnosis ; Endocarditis/etiology ; Heart Valve Prosthesis/adverse effects ; Humans
    Language English
    Publishing date 2022-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3701: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 272: Show issues
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  2. Article ; Online: Transcatheter Edge-to-Edge Repair for Left Atrioventricular Valve Cleft After Previously Repaired Complete Atrioventricular Canal Defect in Down Syndrome.

    Mital, Rohit / Ramakrishna, Satvik / Judson, Gregory L / Watt, Clifton / Tolstrup, Kirsten / Mahadevan, Vaikom S

    CASE (Philadelphia, Pa.)

    2022  Volume 7, Issue 1, Page(s) 35–38

    Language English
    Publishing date 2022-11-09
    Publishing country United States
    Document type Case Reports
    ISSN 2468-6441
    ISSN (online) 2468-6441
    DOI 10.1016/j.case.2022.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Implantable cardioverter-defibrillator placement among patients with left ventricular ejection fraction ≤35 % at least 40 days after acute myocardial infarction.

    Judson, Gregory L / Cohen, Beth E / Muniyappa, Anoop / Raitt, Merritt H / Shen, Hui / Tarasovsky, Gary / Whooley, Mary A / Dhruva, Sanket S

    American heart journal plus : cardiology research and practice

    2023  Volume 19

    Abstract: Background: Implantable cardioverter-defibrillators (ICDs) reduce the risk of sudden cardiac death among patients with persistently reduced (≤35 %) left ventricular ejection fraction (LVEF) at least 40 days following acute myocardial infarction (AMI). ... ...

    Abstract Background: Implantable cardioverter-defibrillators (ICDs) reduce the risk of sudden cardiac death among patients with persistently reduced (≤35 %) left ventricular ejection fraction (LVEF) at least 40 days following acute myocardial infarction (AMI). Few prior studies have used LVEF measured after the 40-day waiting period to examine primary prevention ICD placement.
    Methods: We sought to determine factors associated with ICD placement among patients who met LVEF criteria post-MI within a large integrated health care system in the U.S by conducting a retrospective cohort study of Veteran patients hospitalized for AMI from 2004 to 2017 who had documented LVEF ≤35 % from echocardiograms performed between 40 and 455 (90 days +1 year) days post-MI. We used multivariable logistic regression to examine factors associated with ICD placement.
    Results: Of 12,893 patients with LVEF ≤35 % at least 40 days post-MI, 2176 (16.9 %) received an ICD between 91- and 455-days post-MI. Younger age, fewer comorbidities, revascularization with PCI, and greater use of GDMT were associated with increased odds of receiving an ICD. However, half of patients treated with a beta-blocker, ACE inhibitor or angiotensin receptor blocker, and mineralocorticoid receptor antagonist prior to LVEF assessment did not receive an ICD. Eligible Black patients were less likely (odds ratio 0.80, 95 % confidence interval 0.69-0.92) to receive an ICD than White patients.
    Conclusion: Many factors affect ICD placement among Veteran patients with a confirmed LVEF ≤35 % at least 40 days post-MI. Greater understanding of factors influencing ICD placement would help clinicians ensure guideline-concordant care.
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6022
    ISSN (online) 2666-6022
    DOI 10.1016/j.ahjo.2022.100186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Conduction System Abnormalities After Transcatheter Aortic Valve Replacement: Mechanism, Prediction, and Management.

    Judson, Gregory L / Agrawal, Harsh / Mahadevan, Vaikom S

    Interventional cardiology clinics

    2019  Volume 8, Issue 4, Page(s) 403–409

    Abstract: Conduction disturbances following TAVR are a common occurrence given the proximity of the various conduction system tissues, including the AV node, His-bundle, and bundle branches to the left ventricular outflow tract and aortic root. Impairment of these ...

    Abstract Conduction disturbances following TAVR are a common occurrence given the proximity of the various conduction system tissues, including the AV node, His-bundle, and bundle branches to the left ventricular outflow tract and aortic root. Impairment of these conduction system abnormalities may necessitate permanent pacemaker implantation, which increases morbidity and mortality, as well as length of stay, for the patient. The incidence, mechanisms, and predictors of conduction abnormalities and treatment options are discussed in this up-to-date review of the topic.
    MeSH term(s) Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Electrocardiography ; Heart Conduction System/injuries ; Heart Conduction System/physiopathology ; Heart Injuries/etiology ; Heart Injuries/physiopathology ; Humans ; Intraoperative Complications ; Transcatheter Aortic Valve Replacement/adverse effects
    Language English
    Publishing date 2019-07-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2019.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection.

    Judson, Gregory L / Kelemen, Benjamin W / Njoroge, Joyce N / Mahadevan, Vaikom S

    Cardiology and therapy

    2020  Volume 9, Issue 2, Page(s) 293–305

    Abstract: The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has ...

    Abstract The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has united researchers from bench to bedside in attempts to understand the pathophysiology of the disease and define optimal treatment strategies. Cardiovascular disease is highly prevalent and a leading cause of death across gender, race, and ethnic groups. As the pandemic spreads, there is increasing concern about the cardiovascular effects of the viral infection and the interaction of infection with existing cardiovascular disease. Additionally, there are concerns about the cardiac effects of the numerous treatment agents under study. It will be essential for cardiologists to understand the interplay between underlying cardiac comorbidities, acute cardiovascular effects of COVID-19 disease, and adverse effects of new treatments. Here we describe emerging evidence of the epidemiology of SARS-CoV-2 infection and underlying cardiovascular disease, the evidence for direct myocardial injury in SARS-CoV-2 infection, the specific presentations of cardiovascular involvement by SARS-CoV-2, and the cardiac effects of emerging treatments.
    Keywords covid19
    Language English
    Publishing date 2020-06-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2700626-8
    ISSN 2193-6544 ; 2193-8261
    ISSN (online) 2193-6544
    ISSN 2193-8261
    DOI 10.1007/s40119-020-00184-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Factors associated with remote monitoring adherence for cardiovascular implantable electronic devices.

    Muniyappa, Anoop N / Raitt, Merritt H / Judson, Gregory L / Shen, Hui / Tarasovsky, Gary / Whooley, Mary A / Dhruva, Sanket S

    Heart rhythm

    2022  Volume 19, Issue 9, Page(s) 1499–1507

    Abstract: Background: Professional societies strongly recommend remote monitoring (RM) of all cardiac implantable electronic devices, and higher RM adherence is associated with improved patient outcomes. However, adherence with RM is suboptimal.: Objective: ... ...

    Abstract Background: Professional societies strongly recommend remote monitoring (RM) of all cardiac implantable electronic devices, and higher RM adherence is associated with improved patient outcomes. However, adherence with RM is suboptimal.
    Objective: The purpose of this study was to better understand factors associated with RM adherence.
    Methods: We linked RM data from the Veterans Affairs National Cardiac Device Surveillance Program to clinical data for patients monitored between October 25, 2018, and October 24, 2020. RM adherence was defined as the percentage of days covered by an RM transmission during the study period. Patients were classified into 3 categories: complete (100% of days covered by an RM transmission), intermediate (above median in patients with <100% adherence), and low (below median in patients with <100% adherence) adherence. We used multivariable logistic regression to examine patient, device, and facility characteristics associated with adherence.
    Results: In 52,574 patients, average RM adherence was 71.9%. Only 30.9% (16,224) of patients had complete RM adherence. Black or African American patients had a lower odds of complete RM adherence than white patients (odds ratio 0.88; 95% confidence interval 0.82-0.94), and Hispanic or Latino patients had a lower odds of complete RM adherence (odds ratio 0.79; 95% confidence interval 0.70-0.89) than non-Hispanic or Latino patients. Dementia, depression, and posttraumatic stress disorder were associated with a lower odds of RM adherence.
    Conclusion: There are significant disparities in RM adherence by race, ethnicity, and neuropsychiatric comorbidities. These findings can inform strategies to improve health equity and ensure that all patients with cardiac implantable electronic devices receive the evidence-based clinical benefits of RM.
    MeSH term(s) Defibrillators, Implantable ; Electronics ; Humans ; Monitoring, Physiologic ; Remote Sensing Technology
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2022.04.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6278: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection

    Judson, Gregory L. / Kelemen, Benjamin W. / Njoroge, Joyce N. / Mahadevan, Vaikom S.

    Cardiology and Therapy ; ISSN 2193-8261 2193-6544

    2020  

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s40119-020-00184-5
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: From vision toward best practices: Evaluating

    Reardon, Anthony J F / Farmahin, Reza / Williams, Andrew / Meier, Matthew J / Addicks, Gregory C / Yauk, Carole L / Matteo, Geronimo / Atlas, Ella / Harrill, Joshua / Everett, Logan J / Shah, Imran / Judson, Richard / Ramaiahgari, Sreenivasa / Ferguson, Stephen S / Barton-Maclaren, Tara S

    Frontiers in toxicology

    2023  Volume 5, Page(s) 1194895

    Abstract: The growing number of chemicals in the current consumer and industrial markets presents a major challenge for regulatory programs faced with the need to assess the potential risks they pose to human and ecological health. The increasing demand for hazard ...

    Abstract The growing number of chemicals in the current consumer and industrial markets presents a major challenge for regulatory programs faced with the need to assess the potential risks they pose to human and ecological health. The increasing demand for hazard and risk assessment of chemicals currently exceeds the capacity to produce the toxicity data necessary for regulatory decision making, and the applied data is commonly generated using traditional approaches with animal models that have limited context in terms of human relevance. This scenario provides the opportunity to implement novel, more efficient strategies for risk assessment purposes. This study aims to increase confidence in the implementation of new approach methods in a risk assessment context by using a parallel analysis to identify data gaps in current experimental designs, reveal the limitations of common approaches deriving transcriptomic points of departure, and demonstrate the strengths in using high-throughput transcriptomics (HTTr) to derive practical endpoints. A uniform workflow was applied across six curated gene expression datasets from concentration-response studies containing 117 diverse chemicals, three cell types, and a range of exposure durations, to determine tPODs based on gene expression profiles. After benchmark concentration modeling, a range of approaches was used to determine consistent and reliable tPODs. High-throughput toxicokinetics were employed to translate
    Language English
    Publishing date 2023-05-23
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3080
    ISSN (online) 2673-3080
    DOI 10.3389/ftox.2023.1194895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection

    Judson, Gregory L / Kelemen, Benjamin W / Njoroge, Joyce N / Mahadevan, Vaikom S

    Cardiol Ther

    Abstract: The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has ...

    Abstract The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has united researchers from bench to bedside in attempts to understand the pathophysiology of the disease and define optimal treatment strategies. Cardiovascular disease is highly prevalent and a leading cause of death across gender, race, and ethnic groups. As the pandemic spreads, there is increasing concern about the cardiovascular effects of the viral infection and the interaction of infection with existing cardiovascular disease. Additionally, there are concerns about the cardiac effects of the numerous treatment agents under study. It will be essential for cardiologists to understand the interplay between underlying cardiac comorbidities, acute cardiovascular effects of COVID-19 disease, and adverse effects of new treatments. Here we describe emerging evidence of the epidemiology of SARS-CoV-2 infection and underlying cardiovascular disease, the evidence for direct myocardial injury in SARS-CoV-2 infection, the specific presentations of cardiovascular involvement by SARS-CoV-2, and the cardiac effects of emerging treatments.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #597878
    Database COVID19

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  10. Article ; Online: Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection.

    Judson, Gregory L / Kelemen, Benjamin W / Njoroge, Joyce N / Mahadevan, Vaikom S

    Cardiology and therapy, vol 9, iss 2

    2020  

    Abstract: The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has ...

    Abstract The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has profoundly impacted all fields of medicine. Infection with SARS-CoV-2 and the resulting coronavirus of 2019 (COVID-19) syndrome has multiorgan effects. The pandemic has united researchers from bench to bedside in attempts to understand the pathophysiology of the disease and define optimal treatment strategies. Cardiovascular disease is highly prevalent and a leading cause of death across gender, race, and ethnic groups. As the pandemic spreads, there is increasing concern about the cardiovascular effects of the viral infection and the interaction of infection with existing cardiovascular disease. Additionally, there are concerns about the cardiac effects of the numerous treatment agents under study. It will be essential for cardiologists to understand the interplay between underlying cardiac comorbidities, acute cardiovascular effects of COVID-19 disease, and adverse effects of new treatments. Here we describe emerging evidence of the epidemiology of SARS-CoV-2 infection and underlying cardiovascular disease, the evidence for direct myocardial injury in SARS-CoV-2 infection, the specific presentations of cardiovascular involvement by SARS-CoV-2, and the cardiac effects of emerging treatments.
    Keywords COVID-19 ; Cardiovascular implications ; Coronavirus ; SARS ; covid19
    Publishing date 2020-12-01
    Publisher eScholarship, University of California
    Publishing country us
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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