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  1. Book ; Online: TAO Conceptual Design Report

    JUNO Collaboration / Abusleme, Angel / Adam, Thomas / Ahmad, Shakeel / Aiello, Sebastiano / Akram, Muhammad / Ali, Nawab / An, Fengpeng / An, Guangpeng / An, Qi / Andronico, Giuseppe / Anfimov, Nikolay / Antonelli, Vito / Antoshkina, Tatiana / Asavapibhop, Burin / de André, João Pedro Athayde Marcondes / Auguste, Didier / Babic, Andrej / Baldini, Wander /
    Barresi, Andrea / Baussan, Eric / Bellato, Marco / Bergnoli, Antonio / Bernieri, Enrico / Biare, David / Birkenfeld, Thilo / Blin, Sylvie / Blum, David / Blyth, Simon / Bolshakova, Anastasia / Bongrand, Mathieu / Bordereau, Clément / Breton, Dominique / Brigatti, Augusto / Brugnera, Riccardo / Budano, Antonio / Buscemi, Mario / Busto, Jose / Butorov, Ilya / Cabrera, Anatael / Cai, Hao / Cai, Xiao / Cai, Yanke / Cai, Zhiyan / Cammi, Antonio / Campeny, Agustin / Cao, Chuanya / Cao, Guofu / Cao, Jun / Caruso, Rossella / Cerna, Cédric / Chakaberia, Irakli / Chang, Jinfan / Chang, Yun / Chen, Pingping / Chen, Po-An / Chen, Shaomin / Chen, Shenjian / Chen, Xurong / Chen, Yi-Wen / Chen, Yixue / Chen, Yu / Chen, Zhang / Cheng, Jie / Cheng, Yaping / Chepurnov, Alexander / Chiesa, Davide / Chimenti, Pietro / Chukanov, Artem / Chuvashova, Anna / Claverie, Gérard / Clementi, Catia / Clerbaux, Barbara / Di Lorenzo, Selma Conforti / Corti, Daniele / Costa, Salvatore / Corso, Flavio Dal / De La Taille, Christophe / Deng, Jiawei / Deng, Zhi / Deng, Ziyan / Depnering, Wilfried / Diaz, Marco / Ding, Xuefeng / Ding, Yayun / Dirgantara, Bayu / Dmitrievsky, Sergey / Dohnal, Tadeas / Donchenko, Georgy / Dong, Jianmeng / Dornic, Damien / Doroshkevich, Evgeny / Dracos, Marcos / Druillole, Frédéric / Du, Shuxian / Dusini, Stefano / Dvorak, Martin / Enqvist, Timo / Enzmann, Heike / Fabbri, Andrea / Fajt, Lukas / Fan, Donghua / Fan, Lei / Fang, Can / Fang, Jian / Fatkina, Anna / Fedoseev, Dmitry / Fekete, Vladko / Feng, Li-Cheng / Feng, Qichun / Ford, Richard / Formozov, Andrey / Fournier, Amélie / Gan, Haonan / Gao, Feng / Garfagnini, Alberto / Göttel, Alexandre / Genster, Christoph / Giammarchi, Marco / Giaz, Agnese / Giudice, Nunzio / Giuliani, Franco / Gonchar, Maxim / Gong, Guanghua / Gong, Hui / Gorchakov, Oleg / Gornushkin, Yuri / Grassi, Marco / Grewing, Christian / Gromov, Maxim / Gromov, Vasily / Gu, Minghao / Gu, Xiaofei / Gu, Yu / Guan, Mengyun / Guardone, Nunzio / Gul, Maria / Guo, Cong / Guo, Jingyuan / Guo, Wanlei / Guo, Xinheng / Guo, Yuhang / Haacke, Michael / Hackspacher, Paul / Hagner, Caren / Han, Ran / Han, Yang / He, Miao / He, Wei / Heinz, Tobias / Hellmuth, Patrick / Heng, Yuekun / Herrera, Rafael / Hong, Daojin / Hou, Shaojing / Hsiung, Yee / Hu, Bei-Zhen / Hu, Hang / Hu, Jianrun / Hu, Jun / Hu, Shouyang / Hu, Tao / Hu, Zhuojun / Huang, Chunhao / Huang, Guihong / Huang, Hanxiong / Huang, Qinhua / Huang, Wenhao / Huang, Xingtao / Huang, Yongbo / Hui, Jiaqi / Huo, Lei / Huo, Wenju / Huss, Cédric / Hussain, Safeer / Insolia, Antonio / Ioannisian, Ara / Isocrate, Roberto / Jen, Kuo-Lun / Ji, Xiaolu / Ji, Xingzhao / Jia, Huihui / Jia, Junji / Jian, Siyu / Jiang, Di / Jiang, Xiaoshan / Jin, Ruyi / Jing, Xiaoping / Jollet, Cécile / Joutsenvaara, Jari / Jungthawan, Sirichok / Kalousis, Leonidas / Kampmann, Philipp / Kang, Li / Karagounis, Michael / Kazarian, Narine / Khan, Amir / Khan, Waseem / Khosonthongkee, Khanchai / Kinz, Patrick / Korablev, Denis / Kouzakov, Konstantin / Krasnoperov, Alexey / Krokhaleva, Svetlana / Krumshteyn, Zinovy / Kruth, Andre / Kutovskiy, Nikolay / Kuusiniemi, Pasi / Lachenmaier, Tobias / Landini, Cecilia / Leblanc, Sébastien / Lefevre, Frederic / Lei, Liping / Lei, Ruiting / Leitner, Rupert / Leung, Jason / Li, Chao / Li, Demin / Li, Fei / Li, Fule / Li, Haitao / Li, Huiling / Li, Jiaqi / Li, Jin / Li, Kaijie / Li, Mengzhao / Li, Nan / Li, Qingjiang / Li, Ruhui / Li, Shanfeng / Li, Shuaijie / Li, Tao / Li, Teng / Li, Weidong / Li, Weiguo / Li, Xiaomei / Li, Xiaonan / Li, Xinglong / Li, Yi / Li, Yufeng / Li, Zhibing / Li, Ziyuan / Liang, Hao / Liang, Jingjing / Liebau, Daniel / Limphirat, Ayut / Limpijumnong, Sukit / Lin, Guey-Lin / Lin, Shengxin / Lin, Tao / Ling, Jiajie / Lippi, Ivano / Liu, Fang / Liu, Haidong / Liu, Hongbang / Liu, Hongjuan / Liu, Hongtao / Liu, Hu / Liu, Hui / Liu, Jianglai / Liu, Jinchang / Liu, Min / Liu, Qian / Liu, Qin / Liu, Runxuan / Liu, Shuangyu / Liu, Shubin / Liu, Shulin / Liu, Xiaowei / Liu, Yan / Lokhov, Alexey / Lombardi, Paolo / Lombardo, Claudio / Loo, Kai / Lu, Chuan / Lu, Haoqi / Lu, Jingbin / Lu, Junguang / Lu, Shuxiang / Lu, Xiaoxu / Lubsandorzhiev, Bayarto / Lubsandorzhiev, Sultim / Ludhova, Livia / Luo, Fengjiao / Luo, Guang / Luo, Pengwei / Luo, Shu / Luo, Wuming / Lyashuk, Vladimir / Ma, Qiumei / Ma, Si / Ma, Xiaoyan / Ma, Xubo / Maalmi, Jihane / Malyshkin, Yury / Mantovani, Fabio / Manzali, Francesco / Mao, Xin / Mao, Yajun / Mari, Stefano M. / Marini, Filippo / Marium, Sadia / Martellini, Cristina / Martin-Chassard, Gisele / Martini, Agnese / Mayilyan, Davit / Müller, Axel / Meng, Yue / Meregaglia, Anselmo / Meroni, Emanuela / Meyhöfer, David / Mezzetto, Mauro / Miller, Jonathan / Miramonti, Lino / Monforte, Salvatore / Montini, Paolo / Montuschi, Michele / Morozov, Nikolay / Muralidharan, Pavithra / Nastasi, Massimiliano / Naumov, Dmitry V. / Naumova, Elena / Nemchenok, Igor / Nikolaev, Alexey / Ning, Feipeng / Ning, Zhe / Nunokawa, Hiroshi / Oberauer, Lothar / Ochoa-Ricoux, Juan Pedro / Olshevskiy, Alexander / Orestano, Domizia / Ortica, Fausto / Pan, Hsiao-Ru / Paoloni, Alessandro / Parkalian, Nina / Parmeggiano, Sergio / Payupol, Teerapat / Pei, Yatian / Pelliccia, Nicomede / Peng, Anguo / Peng, Haiping / Perrot, Frédéric / Petitjean, Pierre-Alexandre / Petrucci, Fabrizio / Rico, Luis Felipe Piñeres / Popov, Artyom / Poussot, Pascal / Pratumwan, Wathan / Previtali, Ezio / Qi, Fazhi / Qi, Ming / Qian, Sen / Qian, Xiaohui / Qiao, Hao / Qin, Zhonghua / Qiu, Shoukang / Rajput, Muhammad / Ranucci, Gioacchino / Raper, Neill / Re, Alessandra / Rebber, Henning / Rebii, Abdel / Ren, Bin / Ren, Jie / Rezinko, Taras / Ricci, Barbara / Robens, Markus / Roche, Mathieu / Rodphai, Narongkiat / Romani, Aldo / Roskovec, Bedřich / Roth, Christian / Ruan, Xiangdong / Ruan, Xichao / Rujirawat, Saroj / Rybnikov, Arseniy / Sadovsky, Andrey / Saggese, Paolo / Salamanna, Giuseppe / Sanfilippo, Simone / Sangka, Anut / Sanguansak, Nuanwan / Sawangwit, Utane / Sawatzki, Julia / Sawy, Fatma / Schever, Michaela / Schuler, Jacky / Schwab, Cédric / Schweizer, Konstantin / Selivanov, Dmitry / Selyunin, Alexandr / Serafini, Andrea / Settanta, Giulio / Settimo, Mariangela / Shahzad, Muhammad / Shi, Gang / Shi, Jingyan / Shi, Yongjiu / Shutov, Vitaly / Sidorenkov, Andrey / Simkovic, Fedor / Sirignano, Chiara / Siripak, Jaruchit / Sisti, Monica / Slupecki, Maciej / Smirnov, Mikhail / Smirnov, Oleg / Sogo-Bezerra, Thiago / Songwadhana, Julanan / Soonthornthum, Boonrucksar / Sotnikov, Albert / Sramek, Ondrej / Sreethawong, Warintorn / Stahl, Achim / Stanco, Luca / Stankevich, Konstantin / Stefanik, Dus / Steiger, Hans / Steinmann, Jochen / Sterr, Tobias / Stock, Matthias Raphael / Strati, Virginia / Studenikin, Alexander / Sun, Gongxing / Sun, Shifeng / Sun, Xilei / Sun, Yongjie / Sun, Yongzhao / Suwonjandee, Narumon / Szelezniak, Michal / Tang, Jian / Tang, Qiang / Tang, Quan / Tang, Xiao / Tietzsch, Alexander / Tkachev, Igor / Tmej, Tomas / Treskov, Konstantin / Triossi, Andrea / Troni, Giancarlo / Trzaska, Wladyslaw / Tuve, Cristina / van Waasen, Stefan / Boom, Johannes Vanden / Vanroyen, Guillaume / Vassilopoulos, Nikolaos / Vedin, Vadim / Verde, Giuseppe / Vialkov, Maxim / Viaud, Benoit / Volpe, Cristina / Vorobel, Vit / Votano, Lucia / Walker, Pablo / Wang, Caishen / Wang, Chung-Hsiang / Wang, En / Wang, Guoli / Wang, Jian / Wang, Jun / Wang, Kunyu / Wang, Lu / Wang, Meifen / Wang, Meng / Wang, Ruiguang / Wang, Siguang / Wang, Wei / Wang, Wenshuai / Wang, Xi / Wang, Xiangyue / Wang, Yangfu / Wang, Yaoguang / Wang, Yi / Wang, Yifang / Wang, Yuanqing / Wang, Yuman / Wang, Zhe / Wang, Zheng / Wang, Zhimin / Wang, Zongyi / Watcharangkool, Apimook / Wei, Lianghong / Wei, Wei / Wei, Yadong / Wen, Liangjian / Wiebusch, Christopher / Wong, Steven Chan-Fai / Wonsak, Bjoern / Wu, Diru / Wu, Fangliang / Wu, Qun / Wu, Wenjie / Wu, Zhi / Wurm, Michael / Wurtz, Jacques / Wysotzki, Christian / Xi, Yufei / Xia, Dongmei / Xie, Yuguang / Xie, Zhangquan / Xing, Zhizhong / Xu, Benda / Xu, Donglian / Xu, Fanrong / Xu, Jilei / Xu, Jing / Xu, Meihang / Xu, Yin / Xu, Yu / Yan, Baojun / Yan, Xiongbo / Yan, Yupeng / Yang, Anbo / Yang, Changgen / Yang, Huan / Yang, Jie / Yang, Lei / Yang, Xiaoyu / Yang, Yifan / Yao, Haifeng / Yasin, Zafar / Ye, Jiaxuan / Ye, Mei / Yegin, Ugur / Yermia, Frédéric / Yi, Peihuai / Yin, Xiangwei / You, Zhengyun / Yu, Boxiang / Yu, Chiye / Yu, Chunxu / Yu, Hongzhao / Yu, Miao / Yu, Xianghui / Yu, Zeyuan / Yuan, Chengzhuo / Yuan, Ying / Yuan, Zhenxiong / Yuan, Ziyi / Yue, Baobiao / Zafar, Noman / Zambanini, Andre / Zeng, Pan / Zeng, Shan / Zeng, Tingxuan / Zeng, Yuda / Zhan, Liang / Zhang, Feiyang / Zhang, Guoqing / Zhang, Haiqiong / Zhang, Honghao / Zhang, Jiawen / Zhang, Jie / Zhang, Jingbo / Zhang, Peng / Zhang, Qingmin / Zhang, Shiqi / Zhang, Tao / Zhang, Xiaomei / Zhang, Xuantong / Zhang, Yan / Zhang, Yinhong / Zhang, Yiyu / Zhang, Yongpeng / Zhang, Yuanyuan / Zhang, Yumei / Zhang, Zhenyu / Zhang, Zhijian / Zhao, Fengyi / Zhao, Jie / Zhao, Rong / Zhao, Shujun / Zhao, Tianchi / Zheng, Dongqin / Zheng, Hua / Zheng, Minshan / Zheng, Yangheng / Zhong, Weirong / Zhou, Jing / Zhou, Li / Zhou, Nan / Zhou, Shun / Zhou, Xiang / Zhu, Jiang / Zhu, Kejun / Zhuang, Honglin / Zong, Liang / Zou, Jiaheng

    A Precision Measurement of the Reactor Antineutrino Spectrum with Sub-percent Energy Resolution

    2020  

    Abstract: The Taishan Antineutrino Observatory (TAO, also known as JUNO-TAO) is a satellite experiment ...

    Abstract The Taishan Antineutrino Observatory (TAO, also known as JUNO-TAO) is a satellite experiment of the Jiangmen Underground Neutrino Observatory (JUNO). A ton-level liquid scintillator detector will be placed at about 30 m from a core of the Taishan Nuclear Power Plant. The reactor antineutrino spectrum will be measured with sub-percent energy resolution, to provide a reference spectrum for future reactor neutrino experiments, and to provide a benchmark measurement to test nuclear databases. A spherical acrylic vessel containing 2.8 ton gadolinium-doped liquid scintillator will be viewed by 10 m^2 Silicon Photomultipliers (SiPMs) of >50% photon detection efficiency with almost full coverage. The photoelectron yield is about 4500 per MeV, an order higher than any existing large-scale liquid scintillator detectors. The detector operates at -50 degree C to lower the dark noise of SiPMs to an acceptable level. The detector will measure about 2000 reactor antineutrinos per day, and is designed to be well shielded from cosmogenic backgrounds and ambient radioactivities to have about 10% background-to-signal ratio. The experiment is expected to start operation in 2022.

    Comment: 134 pages, 114 figures
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment ; Nuclear Experiment
    Subject code 660
    Publishing date 2020-05-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Boosting performance of Co-free Li-rich cathode material through regulating the anionic activity by means of the strong TaO bonding.

    Wu, Chao / Li, Heng / Cao, Shuang / Li, Zhi / Zeng, Peng / Chen, Jiarui / Zhu, Xitong / Guo, Xiaowei / Chen, Gairong / Chang, Baobao / Shen, Yongqiang / Wang, Xianyou

    Journal of colloid and interface science

    2022  Volume 628, Issue Pt B, Page(s) 1031–1040

    Abstract: Benefiting from the extra contribution of O redox, Co-free Li-rich layered oxides (LRNMO) can satisfy the requirement of high specific capacities. However, during the high-voltage charging process, lattice oxygen being oxidized to ... ...

    Abstract Benefiting from the extra contribution of O redox, Co-free Li-rich layered oxides (LRNMO) can satisfy the requirement of high specific capacities. However, during the high-voltage charging process, lattice oxygen being oxidized to O
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.08.135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Realizing Tao-Thouless-like state in fractional quantum spin Hall effect.

    Liu, Chen-Rong / Guo, Yao-Wu / Li, Zhuo-Jun / Li, Wei / Chen, Yan

    Scientific reports

    2016  Volume 6, Page(s) 33472

    Abstract: ... that non-trivial fractional topological Tao-Thouless-like quantum state can be realized in the fractional ... Furthermore, the experimental realization of the Tao-Thouless-like state as well as its evolution in optical ...

    Abstract The quest for exotic quantum states of matter has become one of the most challenging tasks in modern condensed matter communications. Interplay between topology and strong electron-electron interactions leads to lots of fascinating effects since the discovery of the fractional quantum Hall effect. Here, we theoretically study the Rashba-type spin-orbit coupling effect on a fractional quantum spin Hall system by means of finite size exact diagonalization. Numerical evidences from the ground degeneracies, states evolutions, entanglement spectra, and static structure factor calculations demonstrate that non-trivial fractional topological Tao-Thouless-like quantum state can be realized in the fractional quantum spin Hall effect in a thin torus geometric structure by tuning the strength of spin-orbit coupling. Furthermore, the experimental realization of the Tao-Thouless-like state as well as its evolution in optical lattices are also proposed. The importance of this prediction provides significant insight into the realization of exotic topological quantum states in optical lattice, and also opens a route for exploring the exotic quantum states in condensed matters in future.
    Language English
    Publishing date 2016-09-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep33472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway.

    Luo, Li-Hua / Li, Dong-Mei / Wang, Yan-Ling / Wang, Kang / Gao, Li-Xin / Li, Shuang / Yang, Ji-Gang / Li, Chun-Lin / Feng, Wei / Guo, Hong

    Biochemical and biophysical research communications

    2017  Volume 491, Issue 4, Page(s) 966–972

    Abstract: Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease. Studies showed that T helper 1 ... Th1), Th2, and Th17 cells play important roles in the pathology of TAO. Tim-3 and its only known ... aims to investigate the role of Tim3/Gal-9 in the inflammatory response of TAO. In this study ...

    Abstract Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease. Studies showed that T helper 1 (Th1), Th2, and Th17 cells play important roles in the pathology of TAO. Tim-3 and its only known ligand Galectin-9 (Gal-9) is related to the suppression of Th1 and Th17 cytokine secretion. This study aims to investigate the role of Tim3/Gal-9 in the inflammatory response of TAO. In this study, the levels of Tim3, Gal-9, and cytokines of Th1 (TNF-α and IFN-γ), Th2 (IL-4), and Th17 (IL-17) cells were analyzed in the blood samples of TAO patients and healthy controls as well as in orbital fibroblasts. Tim3 overexpression and Gal-9 neutralizing antibody were used in TAO and LPS-stimulated control orbital fibroblasts to further investigate the role and mechanism of Tim3/Gal-9 on the inflammation of TAO. We found Tim3 and Gal-9 expression was significantly downregulated in TAO patients and further lower in active TAO than inactive TAO or controls. Th1, Th2, and Th17 cytokines were all increased in TAO patients. Th1 and Th17 cytokines were higher in active TAO patients than in inactive TAO patients, while Th2 cytokines were enhanced in inactive TAO. Tim3 overexpression decreased the levels of Th1 and Th17 cytokines, but not Th2 cytokine in TAO or LPS-stimulated control orbital fibroblasts. These effects were abrogated by Gal-9 neutralizing antibody. Moreover, Tim3 reduced the levels of p-Akt and p-p65 in TAO or LPS-induced control orbital fibroblasts that were reversed by Gal-9 blocking. In conclusion, Tim3/Gal-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-κB signaling pathway.
    MeSH term(s) Adult ; Female ; Galectins/metabolism ; Graves Ophthalmopathy/metabolism ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Humans ; Inflammation/metabolism ; Male ; Middle Aged ; NF-kappa B/antagonists & inhibitors ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
    Chemical Substances Galectins ; HAVCR2 protein, human ; Hepatitis A Virus Cellular Receptor 2 ; LGALS9 protein, human ; NF-kappa B ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2017-09-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2017.07.144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway

    Luo, Li-Hua / Chun-Lin Li / Dong-Mei Li / Hong Guo / Ji-Gang Yang / Kang Wang / Li-Xin Gao / Shuang Li / Wei Feng / Yan-Ling Wang

    Biochemical and biophysical research communications. 2017 Sept. 30, v. 491

    2017  

    Abstract: Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease. Studies showed that T helper 1 ... Th1), Th2, and Th17 cells play important roles in the pathology of TAO. Tim-3 and its only known ... aims to investigate the role of Tim3/Gal-9 in the inflammatory response of TAO. In this study ...

    Abstract Thyroid-associated ophthalmopathy (TAO) is an autoimmune disease. Studies showed that T helper 1 (Th1), Th2, and Th17 cells play important roles in the pathology of TAO. Tim-3 and its only known ligand Galectin-9 (Gal-9) is related to the suppression of Th1 and Th17 cytokine secretion. This study aims to investigate the role of Tim3/Gal-9 in the inflammatory response of TAO. In this study, the levels of Tim3, Gal-9, and cytokines of Th1 (TNF-α and IFN-γ), Th2 (IL-4), and Th17 (IL-17) cells were analyzed in the blood samples of TAO patients and healthy controls as well as in orbital fibroblasts. Tim3 overexpression and Gal-9 neutralizing antibody were used in TAO and LPS-stimulated control orbital fibroblasts to further investigate the role and mechanism of Tim3/Gal-9 on the inflammation of TAO. We found Tim3 and Gal-9 expression was significantly downregulated in TAO patients and further lower in active TAO than inactive TAO or controls. Th1, Th2, and Th17 cytokines were all increased in TAO patients. Th1 and Th17 cytokines were higher in active TAO patients than in inactive TAO patients, while Th2 cytokines were enhanced in inactive TAO. Tim3 overexpression decreased the levels of Th1 and Th17 cytokines, but not Th2 cytokine in TAO or LPS-stimulated control orbital fibroblasts. These effects were abrogated by Gal-9 neutralizing antibody. Moreover, Tim3 reduced the levels of p-Akt and p-p65 in TAO or LPS-induced control orbital fibroblasts that were reversed by Gal-9 blocking. In conclusion, Tim3/Gal-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-κB signaling pathway.
    Keywords autoimmune diseases ; blood sampling ; CD4-positive T-lymphocytes ; fibroblasts ; galectins ; inflammation ; interferon-gamma ; interleukin-17 ; interleukin-4 ; ligands ; neutralization ; neutralizing antibodies ; patients ; secretion ; signal transduction ; tumor necrosis factor-alpha
    Language English
    Dates of publication 2017-0930
    Size p. 966-972.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2017.07.144
    Database NAL-Catalogue (AGRICOLA)

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  6. Book: Taiwan di qu xue hong su ji yin bing bian zhi tan tao

    Zhang, Jian'guo

    2004  

    Author's details Zhang Jian'guo bian zhu
    MeSH term(s) Hemoglobinopathies/genetics ; Hemoglobins/genetics
    Keywords Taiwan
    Language Chinese
    Size 96 p. :, ill. (some col.) ;, 23 cm.
    Edition Di 1 ban.
    Publisher Yi xuan tu shu chu ban she
    Publishing place Taibei Xian Xindian Shi
    Document type Book
    ISBN 9789576167751 ; 9576167752
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Book ; Online: Late Miocene palaeoflora and palaeoclimate of Lincang (China), supplementary data to: Jacques, Fr?d?ric M B; Guo, Shuang-Xing; Su, Tao; Xing, Yao-Wu; Huang, Yong-Jiang; Liu, Yu-Sheng Christopher; Ferguson, David-Kay; Zhou, Zhekun (2011): Quantitative reconstruction of the Late Miocene monsoon climates of southwest China: A case study of the Lincang flora from Yunnan Province. Palaeogeography, Palaeoclimatology, Palaeoecology, 304(3-4), 318-327

    Jacques, Fr?d?ric M B / Ferguson, David-Kay / Guo, Shuang-Xing / Huang, Yong-Jiang / Liu, Yu-Sheng Christopher / Su, Tao / Xing, Yao-Wu / Zhou, Zhekun

    2011  

    Abstract: The Miocene Lincang leaf assemblage is used in this paper as proxy data to reconstruct the palaeoclimate of southwestern Yunnan (SW China) and the evolution of monsoon intensity. Three quantitative methods were chosen for this reconstruction, i.e. Leaf ... ...

    Abstract The Miocene Lincang leaf assemblage is used in this paper as proxy data to reconstruct the palaeoclimate of southwestern Yunnan (SW China) and the evolution of monsoon intensity. Three quantitative methods were chosen for this reconstruction, i.e. Leaf Margin Analysis (LMA), Climate Leaf Analysis Multivariate Program (CLAMP), and the Coexistence Approach (CA). These methods, however, yield inconsistent results, particularly for the precipitation, as also shown in European and other East Asian Cenozoic floras. The wide range of the reconstructed climatic parameters includes the Mean Annual Temperature (MAT) of 18.5-24.7 ?C and the Mean Annual Precipitation (MAP) of 1213-3711 mm. Compared with the modern Lincang climate (MAT, 17.3 ?C; MAP, 1178.7 mm), the Miocene climate is slightly warmer, wetter and has a higher temperature seasonality. A detailed comparison on the palaeoclimatic variables with the coeval Late Miocene Xiaolongtan flora from the eastern part of Yunnan allows us to investigate the development and interactions of both South Asian and East Asian monsoons during the Late Miocene in southwest China, now under strong influence of these monsoon systems. Our results suggest that the monsoon climate has already been established in southwest Yunnan during the Late Miocene. Furthermore, our results support that both Southeast Asian and East Asian monsoons co-occurred in Yunnan during the Late Miocene.
    Language English
    Dates of publication 2011-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/j.palaeo.2010.04.014
    DOI 10.1594/PANGAEA.758946
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book: Guo song tao ri ji

    Guo, Songtao

    1980  

    Title variant Guo Songtao riji
    Institution Hu nan ren min chu ban she
    湖南人民出版社
    Author's details Guo song tao zhu, ben she jiao dian
    Language Chinese
    Dates of publication 1980-1983
    Size 4 v, ill, 21 cm
    Edition Di 1 ban
    Publisher Hu nan ren min chu ban she
    Publishing place Chang sha
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book: Er ke yi nan bing li tao lun

    Guo, Zhicai

    1987  

    Title translation Study of difficult-to-diagnose cases in pediatrics.
    Author's details Guo Zhicai zhu bian
    MeSH term(s) Pediatrics
    Language Chinese
    Size 3, 318 p.
    Edition Di 1 ban.
    Publisher Guangxi ren min chu ban she
    Publishing place Nanning Shi
    Document type Book
    ISBN 9787219002667 ; 7219002661
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Book ; Online: Host Genetics in Viral Pathogenesis and Controls

    An, Ping / Guo, Ju-Tao / Ann Winkler, Cheryl

    2019  

    Keywords Science: general issues ; Medical genetics ;  Viruses ; Genetics ; Host-virus interaction ; Epidemiology ; Immunity
    Size 1 electronic resource (283 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230582
    ISBN 9782889632633 ; 2889632636
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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