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  1. Article ; Online: Frailty as a Predictor of Bleeding and Poor Outcomes After AVR: An Important Observation or a Future Therapeutic Target?

    Kinnaird, Tim

    JACC. Cardiovascular interventions

    2020  Volume 13, Issue 9, Page(s) 1069–1070

    MeSH term(s) Aged ; Aortic Valve Stenosis/surgery ; Frailty/diagnosis ; Heart Valve Prosthesis Implantation ; Humans ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
    Language English
    Publishing date 2020-03-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2020.02.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: "No Such Thing as a Free Lunch": Personalized P2Y

    Kinnaird, Tim

    Journal of the American Heart Association

    2019  Volume 8, Issue 2, Page(s) e011660

    Abstract: See Article by Crimi et al. ...

    Abstract See Article by Crimi et al.
    MeSH term(s) Acute Coronary Syndrome ; Aged ; Clopidogrel ; Humans ; Platelet Aggregation Inhibitors ; Prasugrel Hydrochloride ; Ticlopidine
    Chemical Substances Platelet Aggregation Inhibitors ; Clopidogrel (A74586SNO7) ; Prasugrel Hydrochloride (G89JQ59I13) ; Ticlopidine (OM90ZUW7M1)
    Language English
    Publishing date 2019-01-12
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.118.011660
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Modelling the impact of historic landscape change on soil erosion and degradation.

    Brandolini, Filippo / Kinnaird, Tim C / Srivastava, Aayush / Turner, Sam

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 4949

    Abstract: International policies and guidelines often highlight the divide between 'nature' and 'heritage' in landscape management, and the weakness of monodisciplinary approaches. This study argues that historic agricultural practices have played a key role in ... ...

    Abstract International policies and guidelines often highlight the divide between 'nature' and 'heritage' in landscape management, and the weakness of monodisciplinary approaches. This study argues that historic agricultural practices have played a key role in shaping today's landscapes, creating a heritage which affords opportunities for more sustainable landscape management. The paper develops a new interdisciplinary approach with particular reference to soil loss and degradation over the long term. It presents innovative methods for assessing and modelling how pre-industrial agricultural features can mitigate soil erosion risk in response to current environmental conditions. Landscape archaeology data presented through Historic Landscape Characterisation are integrated in a GIS-RUSLE model to illustrate the impact of varying historic land-uses on soil erosion. The resulting analyses could be used to inform strategies for sustainable land resource planning.
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31334-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply: Rotational Atherectomy: Where Practice Makes Perfect.

    Kinnaird, Tim / Gallagher, Sean / Mamas, Mamas A

    JACC. Cardiovascular interventions

    2021  Volume 14, Issue 17, Page(s) 1957

    MeSH term(s) Angioplasty, Balloon, Coronary ; Atherectomy, Coronary/adverse effects ; Coronary Angiography ; Humans ; Treatment Outcome
    Language English
    Publishing date 2021-09-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2021.07.044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Treatment of patients with diffuse coronary disease: a challenge yet to be solved?

    Kinnaird, Tim / Mamas, Mamas A

    Polish archives of internal medicine

    2019  Volume 129, Issue 6, Page(s) 365–366

    MeSH term(s) Coronary Artery Disease ; Drug-Eluting Stents ; Humans
    Language English
    Publishing date 2019-06-28
    Publishing country Poland
    Document type Journal Article ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.14883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Modelling the impact of historic landscape change on soil erosion and degradation

    Filippo Brandolini / Tim C. Kinnaird / Aayush Srivastava / Sam Turner

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 16

    Abstract: Abstract International policies and guidelines often highlight the divide between ‘nature’ and ‘heritage’ in landscape management, and the weakness of monodisciplinary approaches. This study argues that historic agricultural practices have played a key ... ...

    Abstract Abstract International policies and guidelines often highlight the divide between ‘nature’ and ‘heritage’ in landscape management, and the weakness of monodisciplinary approaches. This study argues that historic agricultural practices have played a key role in shaping today’s landscapes, creating a heritage which affords opportunities for more sustainable landscape management. The paper develops a new interdisciplinary approach with particular reference to soil loss and degradation over the long term. It presents innovative methods for assessing and modelling how pre-industrial agricultural features can mitigate soil erosion risk in response to current environmental conditions. Landscape archaeology data presented through Historic Landscape Characterisation are integrated in a GIS-RUSLE model to illustrate the impact of varying historic land-uses on soil erosion. The resulting analyses could be used to inform strategies for sustainable land resource planning.
    Keywords Medicine ; R ; Science ; Q
    Subject code 710
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Preconception counselling for women on cardiovascular medications.

    Morgan, Holly / Nana, Melanie / Kinnaird, Tim

    European heart journal

    2019  Volume 40, Issue 41, Page(s) 3436–3437

    Language English
    Publishing date 2019-11-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehz690
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  8. Article ; Online: Dating Agricultural Terraces in the Mediterranean Using Luminescence

    Aayush Srivastava / Tim Kinnaird / Christopher Sevara / Justin Allen Holcomb / Sam Turner

    Land, Vol 12, Iss 716, p

    Recent Progress and Challenges

    2023  Volume 716

    Abstract: Agricultural terraces provide farmers in hilly landscapes with effective ways to increase the area available for crops. They mitigate the risks of soil erosion and promote crop productivity by slowing surface water runoff and retaining moisture. As in ... ...

    Abstract Agricultural terraces provide farmers in hilly landscapes with effective ways to increase the area available for crops. They mitigate the risks of soil erosion and promote crop productivity by slowing surface water runoff and retaining moisture. As in other parts of the world, terraces have been constructed and used in the Mediterranean for millennia. The availability of terraced agriculture had important socio-economic, ecological, and environmental implications for past societies. However, the chronology of construction, use, and abandonment of terraces in different regions remains uncertain. A more robust set of chronological data will allow better assessment of whether terrace agriculture was a resilient strategy in the face of past economic or ecological instability and, in turn, inform how terraces could be used to address future agricultural and environmental challenges. In this paper, we review the application of luminescence dating to terrace sediments, the key challenges involved, and the currently published data which include over 250 luminescence ages. We also discuss the use of a multidisciplinary approach involving other geoarchaeological tools (e.g., use of GIS analyses, field-based luminescence readers, and micromorphology) to enhance the ways that past terrace systems can be understood. Terrace systems are inextricably linked to sustainable land use across the Mediterranean. Luminescence dating methods, therefore, have a crucial role to play in understanding the complexities of past and future landscape change.
    Keywords agricultural terraces ; Mediterranean ; luminescence dating ; landscape archaeology ; Agriculture ; S
    Subject code 333
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Sex differences in high-risk but indicated coronary interventions (CHiP): National report from British Cardiovascular Intervention Society Registry.

    Shamkhani, Warkaa / Kinnaird, Tim / Ludman, Peter / Rashid, Muhammad / Mamas, Mamas A

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  Volume 99, Issue 2, Page(s) 447–456

    Abstract: Objective: To assess sex-based differences in clinical outcomes following complex and high-risk but indicated percutaneous coronary intervention (CHiP).: Background: CHiP is increasingly common in contemporary percutaneous coronary intervention (PCI) ...

    Abstract Objective: To assess sex-based differences in clinical outcomes following complex and high-risk but indicated percutaneous coronary intervention (CHiP).
    Background: CHiP is increasingly common in contemporary percutaneous coronary intervention (PCI) practice. Data on sex differences in the type of CHiP procedures undertaken or their associated clinical outcomes are limited.
    Methods: Patients with stable coronary artery disease who underwent CHiP between January 1, 2006, and December 31, 2017, were included. All procedures were stratified by sex. Multivariate logistic regression analyses were performed to investigate the sex-specific adjusted odds ratios (aOR) of in-hospital outcomes.
    Results: Out of 424,290 PCI procedures, 141,610 (33.37%) were CHiP procedures. Overall, 32,129 (23%) of CHiP were undertaken in females. Females were older than males (median: 74.8 vs. 69.1 years). Males had a higher prevalence of previous myocardial infarction (MI) (44.6% vs. 35.6%) and previous PCI (40% vs. 32.5%). The most common variable observed in female patients undergoing CHiP was age >80 (35.4%), followed by prior coronary artery bypass graft (CABG) (24.3%) and severe coronary calcification (22.6%). In contrast, the most common variable in male patients was prior CABG (36%), followed by chronic thrombus occlusion (CTO) PCI (34.4%) and severe coronary calcification (22%). Females had higher odds (aOR) for mortality (aOR: 1.78, 95% CI: [1.4, 2.2]), bleeding (aOR: 1.99, 95% CI: [1.72, 3.2]), and major adverse cardiovascular and cerebral events (aOR: 1.23, 95% CI: [1.09, 1.38]) compared to males.
    Conclusion: In this national analysis of CHiP procedures over 12 years, there were significant sex differences in the type of CHiP procedures undertaken, with females at increased odds for mortality and in-hospital adverse outcomes.
    MeSH term(s) Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/etiology ; Coronary Artery Disease/therapy ; Female ; Humans ; Male ; Percutaneous Coronary Intervention/adverse effects ; Registries ; Risk Factors ; Sex Characteristics ; Treatment Outcome
    Language English
    Publishing date 2022-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Variation in practice for out-of-hospital cardiac arrest treated with percutaneous coronary intervention in England and Wales.

    Rashid, Muhammad / Kinnaird, Tim / Ludman, Peter / Keeble, Thomas R / Mamas, Mamas / Curzen, Nick

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  Volume 100, Issue 3, Page(s) 306–316

    Abstract: Objectives: We assessed the association between total center volume, operator volume, and out-of-hospital cardiac arrest (OHCA) percutaneous coronary intervention (PCI) volume.: Background: Variations between OHCA PCI volume, hospital total PCI, and ... ...

    Abstract Objectives: We assessed the association between total center volume, operator volume, and out-of-hospital cardiac arrest (OHCA) percutaneous coronary intervention (PCI) volume.
    Background: Variations between OHCA PCI volume, hospital total PCI, and primary PCI volume are not well studied and are unlikely to be clinically justifiable.
    Methods: Patients undergoing PCI for the acute coronary syndrome (ACS) between January 1, 2014, and March 31, 2019, in England and Wales were grouped as OHCA PCI and non-OHCA PCI. Spearman's correlation was used to determine the degree of correlation between each hospital PCI volume and OHCA PCI volume.
    Results: Out of 250,088 PCI procedures undertaken for ACS, 12,016 (4.8%) were performed for OHCA, and 238,072 (95.2%) were non-OHCA PCI procedures. The OHCA PCI group were younger [mean age (SD) 63.2 (12.3) and 65.6 (12.5, p < 0.001)], less likely to be female (20.2% vs. 26.9%, p < 0.001) or Black, Asian, and Minority Ethnicity (11.5% vs. 14.8%, p < 0.001) compared to the non-OHCA PCI group. Although there was a degree of correlation between total PCI and OHCA PCI, there was wide variation for both ACS cohort (Spearman correlation R
    Conclusion: These national data demonstrate wide variation in the practice of OHCA PCI both between centers and individuals. These variations are not expected according to clinical factors and require further investigation.
    MeSH term(s) Acute Coronary Syndrome/diagnostic imaging ; Acute Coronary Syndrome/therapy ; Cardiopulmonary Resuscitation ; Female ; Humans ; Male ; Out-of-Hospital Cardiac Arrest/diagnostic imaging ; Out-of-Hospital Cardiac Arrest/therapy ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome ; Wales
    Language English
    Publishing date 2022-06-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30316
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