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  1. Article ; Online: Melanocytic ocular surface squamous neoplasia successfully managed with no-touch excisional biopsy, cryotherapy and amniotic membrane transplantation.

    Giachos, Ioannis / Thaung, Caroline / Ting, Darren Shu Jeng

    Eye (London, England)

    2024  

    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-03069-2
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  2. Article ; Online: ChatGPT in ophthalmology: the dawn of a new era?

    Ting, Darren Shu Jeng / Tan, Ting Fang / Ting, Daniel Shu Wei

    Eye (London, England)

    2023  Volume 38, Issue 1, Page(s) 4–7

    MeSH term(s) Ophthalmology ; Artificial Intelligence
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Editorial
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02619-4
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  3. Article ; Online: Re: Bonini et al.: Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis (Ophthalmology. 2018;125:1332-1343).

    Ting, Darren Shu Jeng

    Ophthalmology

    2019  Volume 126, Issue 2, Page(s) e14–e15

    MeSH term(s) Double-Blind Method ; Humans ; Keratitis ; Nerve Growth Factor ; Trigeminal Nerve Diseases
    Chemical Substances Nerve Growth Factor (9061-61-4)
    Language English
    Publishing date 2019-01-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2018.09.017
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  4. Article ; Online: Comment on: The Impact of COVID-19 on Individuals Across the Spectrum of Visual Impairment.

    Ting, Darren Shu Jeng / Krause, Sherine / Said, Dalia G / Dua, Harminder S

    American journal of ophthalmology

    2021  Volume 230, Page(s) 303–304

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Vision, Low
    Language English
    Publishing date 2021-05-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2021.04.036
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  5. Article ; Online: Large language models in medicine.

    Thirunavukarasu, Arun James / Ting, Darren Shu Jeng / Elangovan, Kabilan / Gutierrez, Laura / Tan, Ting Fang / Ting, Daniel Shu Wei

    Nature medicine

    2023  Volume 29, Issue 8, Page(s) 1930–1940

    Abstract: Large language models (LLMs) can respond to free-text queries without being specifically trained in the task in question, causing excitement and concern about their use in healthcare settings. ChatGPT is a generative artificial intelligence (AI) chatbot ... ...

    Abstract Large language models (LLMs) can respond to free-text queries without being specifically trained in the task in question, causing excitement and concern about their use in healthcare settings. ChatGPT is a generative artificial intelligence (AI) chatbot produced through sophisticated fine-tuning of an LLM, and other tools are emerging through similar developmental processes. Here we outline how LLM applications such as ChatGPT are developed, and we discuss how they are being leveraged in clinical settings. We consider the strengths and limitations of LLMs and their potential to improve the efficiency and effectiveness of clinical, educational and research work in medicine. LLM chatbots have already been deployed in a range of biomedical contexts, with impressive but mixed results. This review acts as a primer for interested clinicians, who will determine if and how LLM technology is used in healthcare for the benefit of patients and practitioners.
    MeSH term(s) Humans ; Artificial Intelligence ; Medicine ; Language ; Software ; Technology
    Language English
    Publishing date 2023-07-17
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02448-8
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  6. Article ; Online: The impact of COVID-19 pandemic on ophthalmology services: are we ready for the aftermath?

    Ting, Darren Shu Jeng / Deshmukh, Rashmi / Said, Dalia G / Dua, Harminder S

    Therapeutic advances in ophthalmology

    2020  Volume 12, Page(s) 2515841420964099

    Language English
    Publishing date 2020-10-20
    Publishing country United States
    Document type Journal Article
    ISSN 2515-8414
    ISSN (online) 2515-8414
    DOI 10.1177/2515841420964099
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  7. Article ; Online: Interface Haze After Descemet Stripping Automated Endothelial Keratoplasty.

    Ting, Darren Shu Jeng / Said, Dalia G / Dua, Harminder S

    JAMA ophthalmology

    2019  Volume 137, Issue 10, Page(s) 1201–1202

    Language English
    Publishing date 2019-08-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2019.2745
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  8. Article ; Online: Acute corneal perforation 1 week following uncomplicated cataract surgery: the implication of undiagnosed dry eye disease and topical NSAIDs.

    Ting, Darren Shu Jeng / Ghosh, Saurabh

    Therapeutic advances in ophthalmology

    2019  Volume 11, Page(s) 2515841419869508

    Abstract: Dry eye disease is a common ocular surface disease in patients who are undergoing cataract surgery. The significance of dry eye disease is often underestimated or overlooked during preoperative assessment of cataract. We report an 80-year-old patient, ... ...

    Abstract Dry eye disease is a common ocular surface disease in patients who are undergoing cataract surgery. The significance of dry eye disease is often underestimated or overlooked during preoperative assessment of cataract. We report an 80-year-old patient, with a background of seropositive rheumatoid arthritis and diabetes, who presented with an acute corneal melt and perforation associated with undiagnosed dry eye disease and use of topical ketorolac 1 week following an uncomplicated cataract surgery. The patient underwent repeated corneal gluing for corneal perforation and was subsequently diagnosed and treated for bilateral moderate-severe dry eye disease. This case highlights the importance of meticulous preoperative assessment and management of the ocular surface, especially in patients with systemic diseases such as rheumatoid arthritis and diabetes prior to cataract surgery. The implication of the use of topical nonsteroidal anti-inflammatory drugs following cataract surgery - which might have contributed to the process of corneal melt in our case - is also discussed.
    Language English
    Publishing date 2019-08-12
    Publishing country United States
    Document type Case Reports
    ISSN 2515-8414
    ISSN (online) 2515-8414
    DOI 10.1177/2515841419869508
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  9. Article ; Online: Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review.

    Ahmmed, Afsara A / Ting, Darren Shu Jeng / Figueiredo, Francisco C

    The ocular surface

    2021  Volume 20, Page(s) 199–211

    Abstract: Ocular surface chemical injury (OSCI) is a common type of ocular emergency that can potentially cause significant and permanent visual impairment. However, the global prevalence, demographic factors, socioeconomic burden, and psychological impact of OSCI ...

    Abstract Ocular surface chemical injury (OSCI) is a common type of ocular emergency that can potentially cause significant and permanent visual impairment. However, the global prevalence, demographic factors, socioeconomic burden, and psychological impact of OSCI have not been well investigated or reported. This review aims to provide a comprehensive overview of these aspects, highlight gaps in the literature, and advocate key strategies in reducing the incidence of OSCI. OSCI was responsible for 0.1-15% of all ocular emergency presentations, with an estimated incidence of 5.1-50 per 100,000 population-year. Young working adult men were the most at-risk group, though high rates of OSCI were also observed in young children in developed countries, especially from detergent pods. Low- and middle-income countries were noted to have higher proportions of assault-related and pediatric OSCI cases, often with more severe presentations. Direct and indirect costs for some hospitalized patients led to loss of all personal and household income after the injury. Emergency department costs in the United States were estimated at $106.7 million over four years and costs of treating long term complications such as glaucoma were estimated to be as high as $93,003 over five years. Significant negative impacts on visual and health-related quality of life and psychological well-being have been reported after injury, with higher rates of anxiety, depression, and psychological distress compared to the general population.
    MeSH term(s) Adult ; Burns, Chemical ; Child ; Child, Preschool ; Eye Injuries ; Humans ; Incidence ; Male ; Prevalence ; Quality of Life ; United States
    Language English
    Publishing date 2021-02-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2208578-6
    ISSN 1937-5913 ; 1542-0124
    ISSN (online) 1937-5913
    ISSN 1542-0124
    DOI 10.1016/j.jtos.2021.02.006
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  10. Article ; Online: Correction to: Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance.

    Ting, Darren Shu Jeng / Ho, Charlotte Shan / Deshmukh, Rashmi / Said, Dalia G / Dua, Harminder S

    Eye (London, England)

    2021  Volume 35, Issue 10, Page(s) 2908

    Language English
    Publishing date 2021-05-11
    Publishing country England
    Document type Published Erratum
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-021-01568-0
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