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  1. Article ; Online: Race Differences in Blood Pressure Trajectory After Delivery-A Window Into Opportunities to Decrease Racial Disparities in Maternal Morbidity and Mortality.

    Hirshberg, Adi

    JAMA network open

    2020  Volume 3, Issue 12, Page(s) e2031122

    MeSH term(s) Blood Pressure ; Female ; Healthcare Disparities ; Humans ; Hypertension/epidemiology ; Postpartum Period ; Pregnancy ; Race Factors
    Language English
    Publishing date 2020-12-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2020.31122
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  2. Article ; Online: Reducing Disparities Using Telehealth Approaches for Postdelivery Preeclampsia Care.

    Kern-Goldberger, Adina / Hirshberg, Adi

    Clinical obstetrics and gynecology

    2021  Volume 64, Issue 2, Page(s) 375–383

    Abstract: The management of hypertensive disease of pregnancy presents an ongoing challenge after patients are discharged from delivery hospitalizations. Preeclampsia and other forms of postpartum hypertension increase the risk for severe maternal morbidity and ... ...

    Abstract The management of hypertensive disease of pregnancy presents an ongoing challenge after patients are discharged from delivery hospitalizations. Preeclampsia and other forms of postpartum hypertension increase the risk for severe maternal morbidity and mortality in the postpartum period, and both hypertension and its associated adverse events disproportionately affect black women. With its ability to transcend barriers to health care access, telemedicine can facilitate high-quality postpartum care delivery for preeclampsia management and thereby reduce racial disparities in obstetric care and outcomes. Here we discuss racial disparities in preeclampsia and the challenge of providing equitable postpartum preeclampsia care. We then describe the utility of novel telemedicine platforms and their application to combat these disparities in preeclampsia care.
    MeSH term(s) Black or African American ; Female ; Health Services Accessibility ; Humans ; Postpartum Period ; Pre-Eclampsia/therapy ; Pregnancy ; Telemedicine
    Language English
    Publishing date 2021-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391207-3
    ISSN 1532-5520 ; 0009-9201
    ISSN (online) 1532-5520
    ISSN 0009-9201
    DOI 10.1097/GRF.0000000000000605
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  3. Article: Best Practices for Managing Postpartum Hypertension.

    Kumar, Natasha Raj / Hirshberg, Adi / Srinivas, Sindhu K

    Current obstetrics and gynecology reports

    2022  Volume 11, Issue 3, Page(s) 159–168

    Abstract: Purpose of review: Patients remain at risk for persistent and de novo postpartum hypertension related to pregnancy. This review aims to summarize the current definitions, clinical practices, and novel systems innovations and therapies for postpartum ... ...

    Abstract Purpose of review: Patients remain at risk for persistent and de novo postpartum hypertension related to pregnancy. This review aims to summarize the current definitions, clinical practices, and novel systems innovations and therapies for postpartum hypertension.
    Recent findings: Recent changes to the definitions of hypertension outside of pregnancy have not yet impacted definitions or management of hypertensive disorders of pregnancy (HDP), though research examining the implications of these new definitions on risks of developing HDP and the resultant sequelae is ongoing. The administration of diuretics has been shown to reduce postpartum hypertension among women with HDP. Widespread implementation of telemedicine models and remote assessment of ambulatory blood pressures has increased data available on postpartum blood pressure trajectories, which may impact clinical management. Additionally, policy changes such as postpartum Medicaid extension and an increasing emphasis on building bridges to primary care in the postpartum period may improve long-term outcomes for women with postpartum hypertension. Prediction models utilizing machine learning are an area of ongoing research to assist with risk assessment in the postpartum period.
    Summary: The clinical management of postpartum hypertension remains focused on blood pressure control and primary care transition for cardiovascular disease risk reduction. In recent years, systemic innovations have improved access through implementation of new care delivery models. However, the implications of changing definitions of hypertension outside of pregnancy, increased data assessing blood pressure trajectories in the postpartum period, and the creation of new risk prediction models utilizing machine learning remain areas of ongoing research.
    Language English
    Publishing date 2022-06-20
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2161-3303
    ISSN 2161-3303
    DOI 10.1007/s13669-022-00343-6
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  4. Article ; Online: Association of a Remote Blood Pressure Monitoring Program With Postpartum Adverse Outcomes.

    Hirshberg, Adi / Zhu, Yifan / Smith-McLallen, Aaron / Srinivas, Sindhu K

    Obstetrics and gynecology

    2023  Volume 141, Issue 6, Page(s) 1163–1170

    Abstract: Objective: To use administrative claims data to evaluate the association of a remote blood pressure monitoring program with adverse postpartum clinical outcomes in patients with a hypertensive disorder of pregnancy.: Methods: This was a retrospective ...

    Abstract Objective: To use administrative claims data to evaluate the association of a remote blood pressure monitoring program with adverse postpartum clinical outcomes in patients with a hypertensive disorder of pregnancy.
    Methods: This was a retrospective cohort study of Independence Blue Cross members with a hypertensive disorder of pregnancy diagnosis across three obstetric hospitals from 2017 to 2021. Patients who were enrolled in twice-daily text-based blood pressure monitoring for 10 days postpartum were compared with two propensity-score matched cohorts of patients who met the program criteria: an asynchronous cohort (cohort A), consisting of patients at any of the three participating hospitals before remote monitoring program implementation, and a contemporaneous cohort (cohort C), consisting of patients at other hospitals during the same time period as clinical use of the program. Patients with less than 16 months of continuous insurance enrollment before delivery were excluded. Claims for adverse clinical outcomes after delivery discharge were evaluated. Health care service utilization and total medical costs were evaluated.
    Results: The 1,700 patients in remote blood pressure monitoring program were matched to 1,021 patients in cohort A and 1,276 in cohort C. Within the first 6 months after delivery, patients enrolled in remote monitoring were less likely to have the composite adverse outcome than those in cohort A (2.9% vs 4.7%; OR 0.61, 95% CI 0.40-0.98). There was no statistically significant difference relative to cohort C (3.2% vs 4.5%; OR 0.71, 95% CI 0.47-1.07). The remote monitoring group had more cardiology visits and fewer postnatal emergency department (ED) visits and readmissions compared with both comparison cohorts. Reductions in ED visits and readmissions drove overall lower total medical costs for the program cohort.
    Conclusion: Patients enrolled in a remote blood pressure monitoring program were less likely to experience an adverse outcome in the first 6 months after delivery. Reductions in ED visits and readmissions resulted in lower postpartum total medical costs compared with both control cohorts. Broad implementation of evidence-based remote monitoring programs may reduce postpartum adverse outcomes, thereby reducing morbidity and mortality in populations such as the one studied here.
    MeSH term(s) Pregnancy ; Female ; Humans ; Retrospective Studies ; Blood Pressure ; Blood Pressure Determination/methods ; Postpartum Period ; Patient Acceptance of Health Care ; Hypertension/diagnosis
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207330-4
    ISSN 1873-233X ; 0029-7844
    ISSN (online) 1873-233X
    ISSN 0029-7844
    DOI 10.1097/AOG.0000000000005197
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  5. Article ; Online: Text message remote monitoring reduced racial disparities in postpartum blood pressure ascertainment.

    Hirshberg, Adi / Sammel, Mary D / Srinivas, Sindhu K

    American journal of obstetrics and gynecology

    2019  Volume 221, Issue 3, Page(s) 283–285

    MeSH term(s) Algorithms ; Blood Pressure Monitoring, Ambulatory/methods ; Continental Population Groups ; Female ; Healthcare Disparities ; Humans ; Hypertension, Pregnancy-Induced/epidemiology ; Patient Compliance ; Patient Readmission/statistics & numerical data ; Postpartum Period ; Text Messaging
    Language English
    Publishing date 2019-05-20
    Publishing country United States
    Document type Letter ; Randomized Controlled Trial
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2019.05.011
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  6. Article ; Online: Epidemiology of maternal morbidity and mortality.

    Hirshberg, Adi / Srinivas, Sindhu K

    Seminars in perinatology

    2017  Volume 41, Issue 6, Page(s) 332–337

    Abstract: Maternal morbidity and mortality remains a significant health care concern in the United States, as the rates continue to rise despite efforts to improve maternal health. In 2013, the United States ranked 60th in maternal mortality worldwide. We review ... ...

    Abstract Maternal morbidity and mortality remains a significant health care concern in the United States, as the rates continue to rise despite efforts to improve maternal health. In 2013, the United States ranked 60th in maternal mortality worldwide. We review the definitions, rates, trends, and top causes of severe maternal morbidity and mortality, as well as risk factors for adverse maternal outcomes. We describe current local and national initiatives in place to reduce maternal morbidity and mortality and offer suggestions for future research.
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752403-1
    ISSN 1558-075X ; 0146-0005
    ISSN (online) 1558-075X
    ISSN 0146-0005
    DOI 10.1053/j.semperi.2017.07.007
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  7. Article ; Online: Pregnancy Watch: remote monitoring of pregnant and postpartum patients with suspected or confirmed COVID-19.

    McCabe, Meaghan G / Gerson, Kristin D / Srinivas, Sindhu K / Hirshberg, Adi

    American journal of obstetrics & gynecology MFM

    2021  Volume 4, Issue 1, Page(s) 100525

    MeSH term(s) COVID-19 ; Female ; Humans ; Postpartum Period ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2
    Language English
    Publishing date 2021-11-08
    Publishing country United States
    Document type Letter
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2021.100525
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  8. Article ; Online: Successful implementation of text-based blood pressure monitoring for postpartum hypertension.

    Triebwasser, Jourdan E / Janssen, Matthew K / Hirshberg, Adi / Srinivas, Sindhu K

    Pregnancy hypertension

    2020  Volume 22, Page(s) 156–159

    Abstract: Objectives: A clinical trial showed postpartum text-based blood pressure (BP) monitoring is effective in meeting clinical guidelines and reduces racial disparities in postpartum hypertension care. Our objective was to compare clinical outcomes to those ... ...

    Abstract Objectives: A clinical trial showed postpartum text-based blood pressure (BP) monitoring is effective in meeting clinical guidelines and reduces racial disparities in postpartum hypertension care. Our objective was to compare clinical outcomes to those from a clinical trial after implementation of the program in a second hospital within our hospital system.
    Study design: Comparison of women randomized to text-based BP monitoring in a clinical trial compared to an implementation cohort clinically enrolled in text-based BP monitoring. BP outcomes and postpartum visit were compared in bivariate and multivariable analyses.
    Main outcome measures: BP ascertainment was defined as at least 1 BP texted during the 10 days of monitoring. American College of Obstetricians and Gynecologists (ACOG) recommendation was defined as BP sent on postpartum day 3-4 and again day 7-10.
    Results: The implementation cohort had 333 women compared to 103 in the trial cohort. The implementation cohort was older (p < 0.001), and more likely to be non-Black race (p < 0.001), married (<0.001), and have commercial insurance (<0.001). BP ascertainment (95.5% vs. 92.2%, adjusted OR 1.41, [95% CI 0.55, 3.58]) and proportion meeting ACOG recommendations (84.7% vs. 81.6%, adjusted OR 0.89 [95% CI 0.48, 1.64]) were similar between groups. There were no differences in BP ascertainment among Black and non-Black women in the trial or implementation cohort.
    Conclusions: Text-based BP monitoring performed similarly in an implementation cohort compared to the trial participants. This program is scalable to manage postpartum hypertension and reduce racial disparities in postpartum care in women with hypertensive disorders of pregnancy.
    MeSH term(s) Adult ; Aftercare/methods ; Blood Pressure Monitoring, Ambulatory/methods ; Female ; Healthcare Disparities ; Humans ; Hypertension/prevention & control ; Postpartum Period ; Pre-Eclampsia/therapy ; Pregnancy ; Randomized Controlled Trials as Topic ; Retrospective Studies ; Text Messaging
    Language English
    Publishing date 2020-09-10
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 2584464-7
    ISSN 2210-7797 ; 2210-7789
    ISSN (online) 2210-7797
    ISSN 2210-7789
    DOI 10.1016/j.preghy.2020.09.001
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  9. Article ; Online: Telemedicine may increase visit completion rates in postpartum patients with preeclampsia.

    Sanghavi, Monika / Packard, Elizabeth / Sperling, Santina / Eberly, Lauren A / Ambrose, Marietta / Julien, Howard M / Hirshberg, Adi / Adusumalli, Sri / Lewey, Jennifer

    PloS one

    2022  Volume 17, Issue 10, Page(s) e0275741

    Abstract: Postpartum cardiovascular (CV) evaluation of women with preeclampsia is recommended to screen for and treat modifiable risk factors to reduce lifetime CV risk. However, attendance at in-person postpartum obstetric and cardiology clinic visits is low. The ...

    Abstract Postpartum cardiovascular (CV) evaluation of women with preeclampsia is recommended to screen for and treat modifiable risk factors to reduce lifetime CV risk. However, attendance at in-person postpartum obstetric and cardiology clinic visits is low. The aim of this study was to compare the completion rate of new patient telemedicine visits to in-person office visits for patients with preeclampsia referred for postpartum hypertension management and CV risk assessment at a single center. There were 236 unique new patient visits scheduled during the study period. The average age was 30.3 years, 73.7% patients were Black, and 56.7% had Medicaid insurance. The completion rate was 32% for in-person clinic visits and 70% for telemedicine visits. Women who did not complete an office visit were more likely to be Black (87% vs. 56%, p < 0.01) and younger (29.1 vs. 31.4 years, p = 0.04) compared to those who completed a visit. Notably, this difference was not seen with telemedicine visits. Telemedicine may provide a novel opportunity to improve the care for blood pressure management and CV risk reduction in a vulnerable population at risk of premature CV disease.
    MeSH term(s) Pregnancy ; United States ; Humans ; Female ; Adult ; Pre-Eclampsia/diagnosis ; Pre-Eclampsia/epidemiology ; Pre-Eclampsia/therapy ; Telemedicine ; Office Visits ; Blood Pressure ; Postpartum Period
    Language English
    Publishing date 2022-10-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0275741
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  10. Article ; Online: Interpregnancy Body Mass Index Changes: Distribution and Impact on Adverse Pregnancy Outcomes in the Subsequent Pregnancy.

    Bender, Whitney / Hirshberg, Adi / Levine, Lisa D

    American journal of perinatology

    2018  Volume 36, Issue 5, Page(s) 517–521

    Abstract: Objective: To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes.: Study design: We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. ...

    Abstract Objective: To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes.
    Study design: We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both pregnancies. Standard BMI categories were used. Adverse pregnancy outcomes included preterm birth at <37 weeks, intrauterine growth restriction (IUGR), pregnancy-related hypertension, and gestational diabetes mellitus (GDM). Women with increased BMI category between pregnancies were compared with those who remained in the same BMI category.
    Results: In total, 537 women were included, of whom 125 (23%) increased BMI category. There was no association between increase in BMI category and risk of preterm birth, IUGR, or pregnancy-related hypertension. Women who increased BMI category had an increased odds of GDM compared with women who remained in the same BMI category (6.4 vs. 2.2%;
    Conclusion: Almost one-quarter of women increased BMI categories between pregnancies. This modifiable risk factor has a significant impact on the risk of GDM.
    MeSH term(s) Adult ; Body Mass Index ; Diabetes, Gestational ; Female ; Fetal Growth Retardation ; Humans ; Hypertension, Pregnancy-Induced ; Obesity, Maternal ; Pregnancy ; Pregnancy Complications ; Pregnancy Outcome ; Premature Birth ; Retrospective Studies ; Risk Factors ; Weight Gain ; Young Adult
    Language English
    Publishing date 2018-09-07
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0038-1670634
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