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  1. Article ; Online: Corrigendum to 'Management of the Diseases of Mesenteric Arteries and Veins: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)' [Eur J Vasc Endovasc Surg 53/4 (2017) 455-457].

    Becquemin, J P

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2018  Volume 56, Issue 6, Page(s) 920

    Language English
    Publishing date 2018-09-25
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2018.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Management of the Diseases of Mesenteric Arteries and Veins: Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS) [corrected].

    Becquemin, J P

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2017  Volume 53, Issue 4, Page(s) 455–457

    MeSH term(s) Mesenteric Arteries ; Specialties, Surgical ; Vascular Surgical Procedures ; Veins
    Language English
    Publishing date 2017-03-30
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2017.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Midterm Results of Physician-Modified Stent Grafts for Thoracoabdominal and Complex Abdominal Aortic Aneurysms Repair.

    Sénémaud, Jean / Becquemin, Jean-Pierre / Chakfé, Nabil / Touma, Joseph / Desgranges, Pascal / Cochennec, Frédéric

    Annals of vascular surgery

    2022  Volume 93, Page(s) 38–47

    Abstract: Background: To assess midterm results of physician-modified stent grafts (PMSG) for the treatment of emergent complex abdominal and thoracoabdominal aortic aneurysms (TAAA) in high-risk patients.: Methods: All consecutive patients with emergent ... ...

    Abstract Background: To assess midterm results of physician-modified stent grafts (PMSG) for the treatment of emergent complex abdominal and thoracoabdominal aortic aneurysms (TAAA) in high-risk patients.
    Methods: All consecutive patients with emergent complex abdominal or TAAA undergoing PMSG technique between January 2012 and July 2019 were retrospectively included. Indications for PMSG were symptomatic aneurysms and rapidly growing aneurysms >70 mm. Ruptured aneurysms were excluded.
    Results: Thirty-three patients (mean age: 74 +/- 11 years) were included. The mean aneurysm diameter was 76 +- 20 mm. Patients presented with TAAA (n = 20, 61%), complex abdominal aortic aneurysms (CAAA, n = 9, 27%), type I endoleak after previous endovascular aneurysm repair (n = 3, 9%) and intramural aortic hematoma (n = 1, 3%). Chimney technique was performed in addition to PMSG in seven cases (21%). Intraoperative adverse events were recorded in seven cases (35%) in the TAAA group and one case (11%) in the CAAA group. In-hospital mortality rate was 15% (n = 3) in the TAAA group and 11% (n = 1) in the CAAA group. Moderate to severe complications were recorded in 45% of cases (n = 15). Spinal cord ischemia occurred in two cases (6%, one case without residual deficit and one with minor motor deficit). One (3%) patient required transient hemodialysis. One patient presented with early aortic rupture and required an open conversion. The mean follow-up duration was 31 months (1-79). Overall survival estimates were 81.4% (95% confidence interval [CI]: 63.1.-91.2) at 1 year and 71.6% (95% CI: 52.6-84.1) at 2 years. Freedom from reintervention rates at 1 and 2 years were 61.2% (95% CI: 41.7-75.9) and 57.4% (95% CI: 37.9-72.8). Target vessel primary patency rates at 1 and 2 years were 99.2% (95% CI: 94.2-99.9) and 97.7% (95% CI: 90.7-99.4).
    Conclusions: PMSG for high-risk patients with complex aneurysms provided acceptable technical success and excellent target vessel patency rates but were associated with a 12% in-hospital mortality rate. Reinterventions were frequent. This technique should be limited to selected high-risk patients for whom the risk of rupture in the short-term is deemed too high to wait for graft manufacturing of custom-made device.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation ; Stents ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/surgery ; Retrospective Studies ; Risk Factors ; Treatment Outcome ; Prosthesis Design ; Time Factors ; Endovascular Procedures ; Aortic Aneurysm, Thoracoabdominal
    Language English
    Publishing date 2022-11-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2022.11.015
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  4. Article ; Online: Bonnes pratiques de l’aérosolthérapie par nébulisation en 2020.

    Dubus, J-C / Becquemin, M-H / Vecellio, L / Chaumuzeau, J-P / Reychler, G

    Revue des maladies respiratoires

    2020  Volume 38, Issue 2, Page(s) 171–176

    Abstract: Nebulization is a drug delivery mode whose prescription and application remain uncertain. A guide to good practice has been proposed by the work group on aerosol therapy of the French Society for Respiratory Diseases, so-called GAT. The previous ... ...

    Title translation Good practice for aerosol therapy by nebulization in 2020.
    Abstract Nebulization is a drug delivery mode whose prescription and application remain uncertain. A guide to good practice has been proposed by the work group on aerosol therapy of the French Society for Respiratory Diseases, so-called GAT. The previous recommendations date from 2007. In addition to an update of data on nebulization, these expert recommendations aim to be of real help to the prescriber.
    MeSH term(s) Administration, Inhalation ; Aerosols ; Drug Delivery Systems ; Humans ; Nebulizers and Vaporizers
    Chemical Substances Aerosols
    Language French
    Publishing date 2020-12-04
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 605743-3
    ISSN 1776-2588 ; 0301-0279 ; 0761-8425
    ISSN (online) 1776-2588
    ISSN 0301-0279 ; 0761-8425
    DOI 10.1016/j.rmr.2020.11.010
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  5. Article ; Online: Results and factors affecting early outcome of fenestrated and/or branched stent grafts for aortic aneurysms: a multicenter prospective study.

    Marzelle, J / Presles, E / Becquemin, J P

    Annals of surgery

    2015  Volume 261, Issue 1, Page(s) 197–206

    Abstract: ... HR) = 2.10; 95% confidence interval (CI): 1.26-3.48; P = 0.0043]. Occurrence of a technical ... complication and duration of intervention significantly influenced both IM (HR = 4.39; 95% CI: 2.05-9.38; P = 0 ... 0001) and CMSC (HR = 3.07; 95% CI: 1.84-5.11; P < 0.0001). Postoperative events associated ...

    Abstract Objective: To present results and to identify predictive factors of early outcome after fenestrated and/or branched endovascular repair (f/b-EVAR) for complex aortic aneurysms, abdominal (AAA) and thoracoabdominal (TAAA).
    Background: Feasibility of f/b-EVAR for complex aneurysms is now established, but little is known about which patients will benefit from this technique.
    Methods: Univariate and multivariate analysis of preoperative and intraoperative factors on postoperative mortality and complications was performed on 268 patients (group 1: juxta- and pararenal AAA; group 2: suprarenal and TAAA IV; group 3: TAAA I, II, III) enrolled in a prospective multicenter trial of f/b-EVAR.
    Results: Thirty-day mortality, in-hospital mortality (IM), and combined mortality and severe complications (CMSC) rates were 6.7%, 10.1%, and 22.0%, respectively. Group belonging (2 or 3 vs 1) was the only preoperative predictive factor of CMSC [hazard ratio (HR) = 2.10; 95% confidence interval (CI): 1.26-3.48; P = 0.0043]. Occurrence of a technical complication and duration of intervention significantly influenced both IM (HR = 4.39; 95% CI: 2.05-9.38; P = 0.0001) and CMSC (HR = 3.07; 95% CI: 1.84-5.11; P < 0.0001). Postoperative events associated with increased IM were spinal cord ischemia (HR = 9.46; 95% CI: 3.98-22.47; P < 0.0001), hemodialysis (HR = 27.44; 95% CI: 12.63-59.61; P < 0.0001), and reintervention (HR = 4.45; 95% CI: 2.03-9.73; P = 0.0002).
    Conclusions: Although promising, f/b-EVAR still carries a significant rate of mortality and complications, mostly related to the complexity of the procedure. In these complex cases, new strategies should be investigated to improve outcomes.
    MeSH term(s) Aged ; Aortic Aneurysm, Abdominal/surgery ; Aortic Aneurysm, Thoracic/surgery ; Blood Vessel Prosthesis Implantation/adverse effects ; Blood Vessel Prosthesis Implantation/methods ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Operative Time ; Prospective Studies ; Stents ; Treatment Outcome
    Language English
    Publishing date 2015-01
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000000612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Hybrid Technique to Treat Iliofemoral Lesions Using a Covered Stent Associated with Open Femoral Repair.

    Bosse, Côme / Becquemin, Jean-Pierre / Touma, Joseph / Desgranges, Pascal / Cochennec, Frédéric

    Annals of vascular surgery

    2019  Volume 66, Page(s) 601–608

    Abstract: Background: To describe a hybrid approach for complex iliofemoral lesions and report short-term and mid-term results.: Methods: In this single-center retrospective study, all consecutive patients (n = 32, 36 limbs) who underwent hybrid repair of ... ...

    Abstract Background: To describe a hybrid approach for complex iliofemoral lesions and report short-term and mid-term results.
    Methods: In this single-center retrospective study, all consecutive patients (n = 32, 36 limbs) who underwent hybrid repair of complex iliofemoral lesions between 2012 and 2017 using a conformable self-expandable covered stent for external iliac artery lesions and open repair of the common femoral artery were included. Lesions were responsible for claudication in 13 (36%) limbs, rest pain in 13 (36%) limbs and tissue loss in 10 (28%) limbs. Over a wire crossing the iliac lesion, the covered stent was deployed, externalized through the femoral arteriotomy, and cut at the iliofemoral junction in such a way that no untreated transition zone remained between the stent and the open reconstruction of the femoral artery.
    Results: Two elderly patients with critical limb ischemia died during the postoperative course, giving in-hospital mortality of 6.2%. Four (12.5%) presented with moderate to severe complications, including one transtibial amputation in a patient who presented with tissue loss at admission. The median follow-up period was 24.1 months (range: 0.8-64 months). One-year and two-year Kaplan-Meier estimates of overall survival were 91% (95% CI: 97-74) and 76% (95% CI: 89-53). One-year and two-year estimates of freedom from major amputation were 96% (95% CI: 99-76) and 91% (95% CI: 97-66). Estimates of primary patency, assisted primary patency, and secondary patency were: 93.7 (95% CI: 77.1-98.4) at 1 year, and 93.7 (95% CI: 77.1-98.4) at 2 years; 96.7% (95% CI: 78.6-99.6) at 1 year, and 96.7% (95% CI: 78.6-99.6) at 2 years; 96.7% (95% CI: 78.6-99.6) at 1 year and 96.7% (95% CI: 78.6-99.6) at 2 years, respectively.
    Conclusions: Our hybrid approach for iliofemoral lesions provided acceptable mortality and good mid-term patency rates. Further studies with long-term followup are needed to evaluate the safety and durability of this technique.
    MeSH term(s) Aged ; Aged, 80 and over ; Amputation ; Combined Modality Therapy ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Endovascular Procedures/mortality ; Female ; Femoral Artery/diagnostic imaging ; Femoral Artery/physiopathology ; Femoral Artery/surgery ; Hospital Mortality ; Humans ; Iliac Artery/diagnostic imaging ; Iliac Artery/physiopathology ; Intermittent Claudication/diagnostic imaging ; Intermittent Claudication/mortality ; Intermittent Claudication/physiopathology ; Intermittent Claudication/therapy ; Limb Salvage ; Male ; Middle Aged ; Peripheral Arterial Disease/diagnostic imaging ; Peripheral Arterial Disease/mortality ; Peripheral Arterial Disease/physiopathology ; Peripheral Arterial Disease/therapy ; Postoperative Complications/mortality ; Postoperative Complications/surgery ; Prosthesis Design ; Retrospective Studies ; Stents ; Time Factors ; Treatment Outcome ; Vascular Patency
    Language English
    Publishing date 2019-12-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2019.12.010
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  7. Article ; Online: Effectiveness of Zilver PTX eluting stent in TASC C/D lesions and restenosis.

    Leopardi, M / Houbballah, R / Becquemin, J P

    The Journal of cardiovascular surgery

    2014  Volume 55, Issue 2, Page(s) 229–234

    Abstract: Aim: The indication for use of drug-eluting stents (DES) in lower limb arteries is still undefined. We report our series of patients treated with Zilver PTS DES, in treating in-stent restenosis (ISR) and Trans-Atlantic Inter-Society Consensus Document ... ...

    Abstract Aim: The indication for use of drug-eluting stents (DES) in lower limb arteries is still undefined. We report our series of patients treated with Zilver PTS DES, in treating in-stent restenosis (ISR) and Trans-Atlantic Inter-Society Consensus Document on Management of Peripheral Arterial Disease (TASC) C/D femoropopliteal lesions.
    Methods: The Zilver PTX DES is a self-expanding nitinol stent with a polymer-free Paclitaxel coating. Patients with symptomatic de novo TASC C/D lesions or IRS lesions of femoropopliteal segment were eligible for enrollment. We evaluated patients at one month, six months and one year after treatment. We used clinical evaluation criteria and US Doppler for primary and secondary patency-free rates.
    Results: From November 2010 to November 2012, we treated 69 patients with DES Zilver PTX. Indication to treat was given in 36 lesions (52%) by an ISR and in 33 cases (48%) by a TASC C/D lesion. Lesions were staged in the superficial femoral artery (SFA) level in 59 patients (85.6%), in the popliteal artery in 6 patients (8.7%), in a femoropopliteal bypass in 4 patients (5.7%). The mean follow-up was 5.3 months (range 1-24). At 12 months the overall primary patency was 85.5%, secondary patency 89.8% and limb salvage 100%.
    Conclusion: Zilver PTX DES seems to be effective in treating TASC C/D lesions and ISR in femoropopliteal lesions at short term. Therefore DES should be recommended when treating those complex lesions.
    MeSH term(s) Aged ; Aged, 80 and over ; Alloys ; Cardiovascular Agents/administration & dosage ; Constriction, Pathologic ; Disease-Free Survival ; Drug-Eluting Stents ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Female ; Humans ; Kaplan-Meier Estimate ; Limb Salvage ; Male ; Middle Aged ; Paclitaxel/administration & dosage ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/physiopathology ; Peripheral Arterial Disease/therapy ; Prosthesis Design ; Recurrence ; Time Factors ; Treatment Outcome ; Ultrasonography, Doppler ; Vascular Patency
    Chemical Substances Alloys ; Cardiovascular Agents ; nitinol (2EWL73IJ7F) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2014-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Awakening of Alice.

    Becquemin, J P / Raux, M / Cochennec, F / Marzelle, J

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2015  Volume 50, Issue 6, Page(s) 825–826

    MeSH term(s) Aortic Aneurysm, Abdominal/surgery ; Blood Vessel Prosthesis Implantation/statistics & numerical data ; Endovascular Procedures/statistics & numerical data ; Female ; Humans ; Male ; Postoperative Complications/epidemiology ; Risk Assessment/methods ; Stents
    Language English
    Publishing date 2015-12
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2015.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Inhaled insulin: a model for pulmonary systemic absorption?

    Becquemin, M-H / Chaumuzeau, J-P

    Revue des maladies respiratoires

    2010  Volume 27, Issue 8, Page(s) e54–65

    Abstract: The European Union recently approved a form of insulin intended to be inhaled. This innovative presentation has the potential to partially or completely replace the injections and thus facilitate starting insulin therapy which is considered with ... ...

    Abstract The European Union recently approved a form of insulin intended to be inhaled. This innovative presentation has the potential to partially or completely replace the injections and thus facilitate starting insulin therapy which is considered with apprehension and often differed. On this occasion, we reviewed the issues raised by this pulmonary route for systemic absorption (anatomical and cytological limits, cellular mechanisms, relevant physical parameters, facilitating chemical cofactors, role of tobacco smoking and of common respiratory diseases). The pharmacokinetics of inhaled and injectable insulins are comparable, apart from an appreciably faster absorption of the former, and both show the same intra-individual variability. The total bioavailability is definitely lower with the inhaled route but is notably increased in smokers. These characteristics can vary according to the inhalation system used. A frequent induced cough, the increase in circulating anti-insulin antibodies, and a potentially higher cost are not really determining obstacles. The indications will have to be clearly specified and the long-term innocuousness of repeated inhalation of such a mitogen, especially in children and former smokers, remains to be fully proven.
    MeSH term(s) Absorption ; Administration, Inhalation ; Adult ; Antibody Formation ; Biological Availability ; Child ; Clinical Trials, Phase III as Topic ; Cough/etiology ; Diabetes Mellitus/drug therapy ; Dry Powder Inhalers ; Equipment Design ; Humans ; Injections ; Insulin/administration & dosage ; Insulin/adverse effects ; Insulin/economics ; Insulin/immunology ; Insulin/pharmacokinetics ; Insulin/therapeutic use ; Lung/metabolism ; Meta-Analysis as Topic ; Models, Biological ; Nebulizers and Vaporizers ; Patient Acceptance of Health Care ; Powders ; Smoking
    Chemical Substances Insulin ; Powders
    Language English
    Publishing date 2010-10
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 605743-3
    ISSN 1776-2588 ; 0301-0279 ; 0761-8425
    ISSN (online) 1776-2588
    ISSN 0301-0279 ; 0761-8425
    DOI 10.1016/j.rmr.2010.04.004
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  10. Article ; Online: Is it time to nail the lid on the coffin of open abdominal aortic aneurysm repair? Not so sure!

    Becquemin, J-P / Schneider, F / Ricco, J-B

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2012  Volume 43, Issue 6, Page(s) 625–626

    MeSH term(s) Aortic Aneurysm, Abdominal/surgery ; Blood Vessel Prosthesis Implantation ; Endovascular Procedures ; Humans
    Language English
    Publishing date 2012-06
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2012.03.015
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