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Article ; Online: Interactive Health Literacy and Symptom Self-management in Patients With Lung Cancer: A Critical Realist Analysis.

Campbell, Julie K / Erickson, Jeanne M

2023

Abstract: Background: Patients with lung cancer experience multiple symptoms requiring self-management. Little is known about how self-management is influenced by interactive health literacy, defined as communicating with healthcare providers to obtain and ... ...

Abstract	Background: Patients with lung cancer experience multiple symptoms requiring self-management. Little is known about how self-management is influenced by interactive health literacy, defined as communicating with healthcare providers to obtain and process information. Objective: This study explored how interactive health literacy relates to symptom self-management among patients with lung cancer. A second aim explored how interactive health literacy might be integrated into the Individual and Family Self-management Theory. Methods: This study used a cross-sectional mixed-methods design. Quantitative data included demographics, the All Aspects of Health Literacy Scale, and the Memorial Symptom Assessment-Short Form. Qualitative data were collected using semistructured interviews. Data analysis followed a critical realist model. Results: Twelve adults who recently received treatment for lung cancer reported an average of 14 symptoms that caused moderate distress. Average interactive health literacy of the sample was in the moderate range. Participants' experiences of self-management differed based on their interactive health literacy. A generative mechanism proposes that those with higher interactive health literacy who accessed online information used this information as a basis for engaging with providers regarding potential symptom self-management strategies. Conclusions: Interactive health literacy skills may play a role in patients' ability and confidence in symptom self-management through interactions with oncology providers. Further research should clarify the relationship between interactive health literacy, self-efficacy, and collaboration with oncology providers. Implications for practice: The patient-provider relationship is a key factor influencing how patients obtain and process symptom self-management information. Oncology providers should implement patient-centered strategies to engage patients in symptom self-management.
Language	English
Publishing date	2023-05-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	391995-x
ISSN	1538-9804 ; 0162-220X
ISSN (online)	1538-9804
ISSN	0162-220X
DOI	10.1097/NCC.0000000000001245
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Article ; Online: The Neuropsychiatry Special Interest Group: a Model for Organizing and Optimizing Member Engagement in a National Organization.

Erickson, Jennifer M / Quinn, Davin K / Kalra, Inder / Roy, Durga

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

2023 Volume 47, Issue 6, Page(s) 700–701

Language	English
Publishing date	2023-09-13
Publishing country	United States
Document type	Letter
ZDB-ID	1045331-3
ISSN	1545-7230 ; 1042-9670
ISSN (online)	1545-7230
ISSN	1042-9670
DOI	10.1007/s40596-023-01854-x
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Zs.B 2043: Show issues

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Article ; Online: Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis.

Adorini, Luciano / Rigbolt, Kristoffer / Feigh, Michael / Roth, Jonathan / Erickson, Mary

PloS one

2024 Volume 19, Issue 4, Page(s) e0300809

Abstract: The nuclear farnesoid X receptor (FXR), a master regulator of bile acid and metabolic homeostasis, is a key target for treatment of nonalcoholic steatohepatitis (NASH). This study compared efficacy of FXR agonists obeticholic acid (OCA) and INT-787 by ... ...

Abstract	The nuclear farnesoid X receptor (FXR), a master regulator of bile acid and metabolic homeostasis, is a key target for treatment of nonalcoholic steatohepatitis (NASH). This study compared efficacy of FXR agonists obeticholic acid (OCA) and INT-787 by liver histopathology, plasma biomarkers of liver damage, and hepatic gene expression profiles in the Amylin liver NASH (AMLN) diet-induced and biopsy-confirmed Lepob/ob mouse model of NASH. Lepob/ob mice were fed the AMLN diet for 12 weeks before liver biopsy and subsequent treatment with vehicle, OCA, or INT-787 for 8 weeks. Hepatic steatosis, inflammation, and fibrosis (liver lipids, galectin-3, and collagen 1a1 [Col1a1], respectively), as well as plasma alanine transaminase (ALT) and aspartate transaminase (AST) levels, were assessed. Hepatic gene expression was assessed in Lepob/ob mice that were fed the AMLN diet for 14 weeks then treated with vehicle, OCA, or INT-787 for 2 weeks. INT-787, which is equipotent to OCA but more hydrophilic, significantly reduced liver lipids, galectin-3, and Col1a1 compared with vehicle, and to a greater extent than OCA. INT-787 significantly reduced plasma ALT and AST levels, whereas OCA did not. INT-787 modulated a substantially greater number of genes associated with FXR signaling, lipid metabolism, and stellate cell activation relative to OCA in hepatic tissue. These findings demonstrate greater efficacy of INT-787 treatment compared with OCA in improving liver histopathology, decreasing liver enzyme levels, and enhancing gene regulation, suggesting superior clinical potential of INT-787 for the treatment of NASH and other chronic liver diseases.
MeSH term(s)	Animals ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/pathology ; Non-alcoholic Fatty Liver Disease/genetics ; Chenodeoxycholic Acid/analogs & derivatives ; Chenodeoxycholic Acid/pharmacology ; Chenodeoxycholic Acid/therapeutic use ; Receptors, Cytoplasmic and Nuclear/agonists ; Receptors, Cytoplasmic and Nuclear/metabolism ; Receptors, Cytoplasmic and Nuclear/genetics ; Mice ; Disease Models, Animal ; Liver/metabolism ; Liver/drug effects ; Liver/pathology ; Male ; Galectin 3/metabolism ; Galectin 3/genetics
Chemical Substances	obeticholic acid (0462Z4S4OZ) ; Chenodeoxycholic Acid (0GEI24LG0J) ; farnesoid X-activated receptor (0C5V0MRU6P) ; Receptors, Cytoplasmic and Nuclear ; Galectin 3 ; Lgals3 protein, mouse
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0300809
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Top advances of the year: Uterine cancer.

Erickson, Britt K / Slomovitz, Brian / Powell, Matthew / Eskander, Ramez N

Cancer

2024

Abstract: Endometrial cancer continues to be the only gynecologic malignancy with a rising incidence and mortality, with both regional and global implications. Combination carboplatin and paclitaxel has been the recognized chemotherapy backbone for the treatment ... ...

Abstract	Endometrial cancer continues to be the only gynecologic malignancy with a rising incidence and mortality, with both regional and global implications. Combination carboplatin and paclitaxel has been the recognized chemotherapy backbone for the treatment of advanced-stage or recurrent disease, with modest clinical outcomes. Over the last year, significant advances were achieved in improving oncologic outcomes by capitalizing on the molecular characterization of this heterogenous disease. These advances include incorporation of immunotherapy, identification of effective hormonal approaches, the evolution of antibody drug conjugates, and utilization of alternate targeted therapies. PLAIN LANGUAGE SUMMARY: The molecular characterization of endometrial cancer has been critical in informing novel treatment strategies. Over the past year, significant gains have been made via the incorporation of immunotherapy, hormonal combinations as well as antibody drug conjugates.
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1429-1
ISSN	1097-0142 ; 0008-543X ; 1934-662X
ISSN (online)	1097-0142
ISSN	0008-543X ; 1934-662X
DOI	10.1002/cncr.35321
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Article ; Online: Moria of Jastrowitz After Bilateral Hippocampal Lesions.

Erickson, Jennifer M / Quinn, Davin K

Journal of the Academy of Consultation-Liaison Psychiatry

2020 Volume 62, Issue 3, Page(s) 357–362

MeSH term(s)	Corneal Stroma ; Hippocampus ; Keratomileusis, Laser In Situ
Language	English
Publishing date	2020-12-13
Publishing country	Netherlands
Document type	Case Reports ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	2667-2960
ISSN (online)	2667-2960
DOI	10.1016/j.jaclp.2020.12.001
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Article: Mesenteric Solitary Fibrous Tumor with High Risk for Aggressive Behavior: A Case Report.

Cucak, Anja / Erickson-Adams, Kaia / Sorrell, Matthew

South Dakota medicine : the journal of the South Dakota State Medical Association

2023 Volume 75, Issue 12, Page(s) 550–552

Abstract: A 64-year-old female presented to the emergency department (ED) with complaints of two days of intermittent fever and chills, progressively worsening back pain, and hematochezia. Initial evaluation and computer tomography (CT) imaging work up revealed a ... ...

Abstract	A 64-year-old female presented to the emergency department (ED) with complaints of two days of intermittent fever and chills, progressively worsening back pain, and hematochezia. Initial evaluation and computer tomography (CT) imaging work up revealed a hypervascular and necrotic appearing pelvic mass, measuring 11.7 x 7.8 x 9.7 cm, closely associated with the inferior mesenteric vein (IMV) in conjunction with portal venous gas. Flexible sigmoidoscopy with biopsy was performed to identify the etiology of the lesion and revealed an ulcerated non-obstructing mass in the recto-sigmoid colon measuring 3 cm in length and involving 1/3 of lumen circumference with oozing present. Interventional radiology (IR) embolization of the feeding vessels was done pre-operatively due to high vascularity of the mass. Pathology of the mass was consistent with a malignant solitary fibrous tumor.
MeSH term(s)	Female ; Humans ; Middle Aged ; Solitary Fibrous Tumors/diagnostic imaging ; Solitary Fibrous Tumors/surgery ; Biopsy ; Portal Vein ; Mesenteric Veins/diagnostic imaging
Language	English
Publishing date	2023-03-09
Publishing country	United States
Document type	Case Reports
ZDB-ID	2278073-7
ISSN	0038-3317
ISSN	0038-3317
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Article ; Online: Development and psychometric evaluation of the Symptom Self-Management Behaviors Tool for adolescents/young adults with cancer.

Stegenga, Kristin / Erickson, Jeanne M / Linder, Lauri / Macpherson, Catherine Fiona / Elswick, R K / Ameringer, Suzanne

Palliative & supportive care

2023 Volume 22, Issue 2, Page(s) 274–280

Abstract: Objectives: Adolescents and Young Adults (AYAs) with cancer experience symptoms related to disease and treatment. To manage these symptoms, they need to develop self-management behaviors, yet no tool exists to assess these behaviors. The Symptom Self- ... ...

Abstract	Objectives: Adolescents and Young Adults (AYAs) with cancer experience symptoms related to disease and treatment. To manage these symptoms, they need to develop self-management behaviors, yet no tool exists to assess these behaviors. The Symptom Self-Management Behaviors Tool (SSMBT) was developed to meet this need. Methods: The study consisted of 2 phases. Phase 1 evaluated content validity, and Phase 2 evaluated reliability and validity. The SSMBT initially contained 14 items with 2 dimensions: (1) behaviors used to Manage Symptoms and (2) behaviors used to communicate with providers regarding symptoms. Four oncology professionals and 5 AYAs with cancer assessed the content validity. Evaluation of reliability and validity involved 61 AYAs with cancer. Reliability was evaluated using Cronbach's alpha. Construct validity was assessed with factor analysis. Discriminant validity was assessed using associations with symptom severity and distress. Results: Content validity evaluation supported the importance of the items. Factor analysis supported a two-factor structure: Manage Symptoms (8 items) and Communicate with Healthcare Providers (4 items) subscales. Internal consistency reliability for the total SSMBT was acceptable with Cronbach's alpha = 0.74. Cronbach's alpha value for the Manage Symptoms subscale was Significance of results: Systematic assessment of behaviors AYAs use is critical for clinical practice and evaluate interventions to improve self-management. The SSMBT demonstrates initial reliability and validity but requires further evaluation for clinical interpretation and future use.
MeSH term(s)	Humans ; Adolescent ; Young Adult ; Surveys and Questionnaires ; Psychometrics ; Reproducibility of Results ; Self-Management ; Neoplasms/complications ; Neoplasms/therapy
Language	English
Publishing date	2023-06-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2454009-2
ISSN	1478-9523 ; 1478-9515
ISSN (online)	1478-9523
ISSN	1478-9515
DOI	10.1017/S1478951523000810
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Zs.A 6697: Show issues

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Article: Active avoidance under social conditions recruits the anterior cingulate cortex in male and female rats.

Ruble, Shannon / Kramer, Cassandra / West, Lexe / Payne, Karissa / Erickson, Greg / Scott, Alyssa / Diehl, Maria

Research square

2024

Abstract: Actively avoiding potential threats is necessary for survival. Most research has focused on the behavioral and neurobiological processes when individuals avoid potential threats alone, under solitary conditions. Therefore, little is known about how ... ...

Abstract	Actively avoiding potential threats is necessary for survival. Most research has focused on the behavioral and neurobiological processes when individuals avoid potential threats alone, under solitary conditions. Therefore, little is known about how social context affects active avoidance. Using a modified version of the platform-mediated avoidance task, we investigated whether the presence of a social partner attenuates freezing responses and promotes greater avoidance learning compared to avoidance learned under solitary conditions. Rats spent a similar percentage of time avoiding during the conditioned tone under both conditions; however, rats trained under social conditions exhibited greater freezing during the tone and lower pressing for food reward compared to solitary rats. Under solitary conditions, we observed greater avoidance in female compared to male rats, which was not present in rats under social conditions. To gain greater mechanistic insight, we optogenetically inactivated glutamatergic projection neurons in the anterior cingulate cortex (ACC) following avoidance training. Photoinactivation of ACC neurons impaired avoidance expression under social conditions both in the presence and absence of the partner. Under solitary conditions, photoinactivation of ACC delayed avoidance in males but blocked avoidance in females. Our findings suggest that avoidance is mediated by the ACC, regardless of social context, and may be dysfunctional in those suffering from trauma-related disorders. Furthermore, sex differences in prefrontal circuits mediating active avoidance warrant further investigation, given that females experience a higher risk of developing anxiety disorders.
Language	English
Publishing date	2024-01-02
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-3750422/v1
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Article: Epidemiology of Digital Dermatitis in Western Canadian Feedlot Cattle.

Erickson, Sarah / Booker, Calvin / Song, Jiming / Janzen, Eugene / Jelinski, Murray / Schwartzkopf-Genswein, Karen

Animals : an open access journal from MDPI

2024 Volume 14, Issue 7

Abstract: Digital dermatitis (DD) is an emerging disease in feedlot cattle. Our objective was to identify animal- and feedlot-level risk factors for DD by analyzing individual animal health records ( ...

Abstract	Digital dermatitis (DD) is an emerging disease in feedlot cattle. Our objective was to identify animal- and feedlot-level risk factors for DD by analyzing individual animal health records (
Language	English
Publishing date	2024-03-29
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani14071040
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Article ; Online: "It Shaped My Future in Ways I Wasn't Prepared for-in the Best Way Possible": Alumni Volunteers' Experiences in an Adapted Sports and Recreation Program.

Wekesser, Meredith / Costa, Guilherme H / Pasik, Piotr J / Erickson, Karl

Adapted physical activity quarterly : APAQ

2023 Volume 40, Issue 2, Page(s) 303–322

Abstract: Adapted sport participation can have many positive benefits for adults with disabilities. However, one barrier to implementing successful adapted sport programs is lack of knowledgeable volunteers who understand accessibility and disability. In fact, ... ...

Abstract	Adapted sport participation can have many positive benefits for adults with disabilities. However, one barrier to implementing successful adapted sport programs is lack of knowledgeable volunteers who understand accessibility and disability. In fact, little is known about volunteers' experiences in adapted sport programs. The purpose of this study was to retrospectively examine experiences of able-bodied volunteers in an adapted sport program. A sample of 105 able-bodied volunteers (Mage = 24.28 ± 1.93) completed an online qualitative survey to share their experiences. Data were analyzed using qualitative thematic analysis, and seven main themes were identified. Results showed that despite differences in initial motives for volunteering, involvement in an adapted sport program was transformative and, for some, life changing. Able-bodied volunteers experienced a wide range of benefits including deeper understanding and awareness of disability and inclusion in sport. Practical recommendations are provided for volunteer-based adapted sport program leaders.
MeSH term(s)	Adult ; Humans ; Retrospective Studies ; Sports for Persons with Disabilities ; Sports ; Disabled Persons ; Volunteers
Language	English
Publishing date	2023-01-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	995992-0
ISSN	1543-2777 ; 0736-5829
ISSN (online)	1543-2777
ISSN	0736-5829
DOI	10.1123/apaq.2022-0046
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