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  1. Article: Comparison of angiographic estimation and invasive hemodynamic measurement of the significance of non-infarct-related residual stenoses in ST-elevation myocardial infarction patients.

    Spacek, Miloslav / Vacha, Jan / Kaminek, Milan / Hutyra, Martin / Nykl, Radomir / Sluka, Martin / Taborsky, Milos

    Archives of medical sciences. Atherosclerotic diseases

    2023  Volume 8, Page(s) e169–e176

    Abstract: Introduction: Up to 50% of patients with ST elevation myocardial infarction (STEMI) have ≥ 50% stenosis in a major non-infarct-related artery. Several studies have evaluated the prognostic value of the completion of revascularization with overall ... ...

    Abstract Introduction: Up to 50% of patients with ST elevation myocardial infarction (STEMI) have ≥ 50% stenosis in a major non-infarct-related artery. Several studies have evaluated the prognostic value of the completion of revascularization with overall inconclusive results. Selection of the stenoses was based on the angiographic evaluation, invasive hemodynamic measurement or the combined approach. It is unknown whether such a selection provides correlation of comparable patient groups.
    Material and methods: We enrolled 51 patients (62.7 ±10.2 years) with acute STEMI and at least one residual (50-90%) stenosis in a non-infarct-related major coronary artery (excluding left main coronary artery). Overall 65 stenoses (67.9 ±10.7%) were evaluated angiographically following primary percutaneous coronary intervention and the hemodynamic significance was estimated with respect to the stenosis severity, caliber of the arterial segment, localization of the stenosis (proximity) as well as the estimated size of the supplied vascular territory. During subsequent hospitalization, invasive measurement of the hemodynamic significance using fractional flow reserve (FFR) was performed to guide the final revascularization strategy (FFR value of ≤ 0.80 considered significant).
    Results: Based on angiographic evaluation, a total of 44 stenoses would be recommended for treatment, whereas only 31 stenoses were revascularized based on FFR measurement. Moreover, visual evaluation and hemodynamic measurement were discrepant in 27 of 65 (41.5%) stenoses.
    Conclusions: We observed a weak correlation between visual angiographic evaluation and invasive hemodynamic measurement. More stents would be implanted based on angiographic evaluation compared to FFR measurement.
    Language English
    Publishing date 2023-12-30
    Publishing country Poland
    Document type Journal Article
    ISSN 2451-0629
    ISSN 2451-0629
    DOI 10.5114/amsad/172971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Complete revascularization of multivessel coronary artery disease in patients with ST elevation acute coronary syndrome - for whom and when? A comprehensive review.

    Spacek, Miloslav / Vacha, Jan / Precek, Jan / Hutyra, Martin / Nykl, Radomir / Sluka, Martin / Taborsky, Milos

    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

    2022  Volume 167, Issue 1, Page(s) 16–23

    Abstract: Atherosclerosis is the most common cause of coronary steno-occlusive disease and acute myocardial infarction is the leading cause of death in industrialized countries. In patients with acute ST elevation myocardial infarction (STEMI), there is ... ...

    Abstract Atherosclerosis is the most common cause of coronary steno-occlusive disease and acute myocardial infarction is the leading cause of death in industrialized countries. In patients with acute ST elevation myocardial infarction (STEMI), there is unquestionable evidence that primary percutaneous coronary intervention providing recanalization of the infarct related artery (IRA) is the preferred reperfusion strategy. Nevertheless, up to 50% of patients with STEMI have multivessel coronary artery disease defined as at least 50% stenosis exclusive of IRA. There is conflicting data regarding the optimal treatment strategy and timing in such patients. Currently, it is assumed that stable patients might benefit from complete revascularization particularly in reducing the need for future unplanned procedures but only culprit lesion should be treated during index procedure in unstable patients. In this article, we provide a comprehensive overview of this important and currently highly debated topic.
    MeSH term(s) Humans ; Coronary Artery Disease/complications ; Coronary Artery Disease/surgery ; ST Elevation Myocardial Infarction/etiology ; ST Elevation Myocardial Infarction/surgery ; Acute Coronary Syndrome/etiology ; Acute Coronary Syndrome/surgery ; Treatment Outcome ; Myocardial Infarction ; Percutaneous Coronary Intervention/adverse effects ; Arrhythmias, Cardiac
    Language English
    Publishing date 2022-06-14
    Publishing country Czech Republic
    Document type Journal Article ; Review
    ZDB-ID 17196-7
    ISSN 1804-7521 ; 1213-8118 ; 0231-5599 ; 0862-481X
    ISSN (online) 1804-7521
    ISSN 1213-8118 ; 0231-5599 ; 0862-481X
    DOI 10.5507/bp.2022.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Karotický stenting - vývoj, trendy a inovace.

    Špaček, Miloslav / Veselka, Josef

    Vnitrni lekarstvi

    2014  Volume 60, Issue 12, Page(s) 1072–1075

    Abstract: Surgical carotid endarterectomy is traditionally considered the standard approach for the treatment of atherosclerotic carotid artery disease based on its long history of favorable outcomes. Many of the patients could, however, be offered carotid artery ... ...

    Title translation Carotid artery stenting - history, trends and innovations.
    Abstract Surgical carotid endarterectomy is traditionally considered the standard approach for the treatment of atherosclerotic carotid artery disease based on its long history of favorable outcomes. Many of the patients could, however, be offered carotid artery stenting (CAS), which has over time evolved into an elaborate method. With proper selection of patients, CAS provides comparable long-term outcomes and very low risk of periprocedural complication. This article summarises the current knowledge, trends and innovations in CAS.
    MeSH term(s) Angioplasty, Balloon/methods ; Carotid Stenosis/surgery ; Carotid Stenosis/therapy ; Endarterectomy, Carotid/methods ; Humans ; Randomized Controlled Trials as Topic ; Recurrence ; Stents ; Treatment Outcome
    Language Czech
    Publishing date 2014-12
    Publishing country Czech Republic
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 138213-5
    ISSN 1801-7592 ; 0042-773X
    ISSN (online) 1801-7592
    ISSN 0042-773X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Carotid Artery Stenting-Historical Context, Trends, and Innovations.

    Spacek, Miloslav / Veselka, Josef

    The International journal of angiology : official publication of the International College of Angiology, Inc

    2015  Volume 24, Issue 3, Page(s) 205–209

    Abstract: Surgical carotid endarterectomy (CEA) has been proven effective in both primary and secondary stroke prevention and, until recently, has been considered the standard treatment approach for patients with severe carotid artery disease. Because of its ... ...

    Abstract Surgical carotid endarterectomy (CEA) has been proven effective in both primary and secondary stroke prevention and, until recently, has been considered the standard treatment approach for patients with severe carotid artery disease. Because of its technical limitations and less favorable outcomes, carotid artery stenting (CAS) has been offered preferably to patients considered to be too comorbid to undergo surgical treatment. However, CAS has evolved over time into a reliable method and is currently considered an alternative to CEA. The aim of this review was to discuss the historical aspects, trends, and innovations in CAS.
    Language English
    Publishing date 2015-08-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1144390-x
    ISSN 1061-1711
    ISSN 1061-1711
    DOI 10.1055/s-0035-1556842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Determination of the prevalence and predictors of ventricular thrombus with assessment of the risk of systemic embolization to the CNS in patients after acute myocardial infarction using magnetic resonance imaging, echocardiography and cardiac markers - a prospective, unicentric, observational study.

    Hudec, Stepan / Hutyra, Martin / Precek, Jan / Latal, Jan / Nykl, Radomir / Spacek, Miloslav / Sluka, Martin / Sanak, Daniel / Tudos, Zbynek / Pastucha, Dalibor / Taborsky, Milos

    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

    2023  

    Abstract: Background: Left ventricular thrombus (LVT) formation is one of the well-known and serious complications of acute myocardial infarction (AMI) due to the risk of systemic arterial embolization (SE). To diagnose LVT, echocardiography (TTE) is used. Late ... ...

    Abstract Background: Left ventricular thrombus (LVT) formation is one of the well-known and serious complications of acute myocardial infarction (AMI) due to the risk of systemic arterial embolization (SE). To diagnose LVT, echocardiography (TTE) is used. Late gadolinium-enhanced cardiovascular magnetic resonance (DE-CMR) is the gold standard for diagnosing LVT.
    Objectives: The aim of this observational study was to determine the role of transthoracic echocardiography and cardiac markers in predicting the occurrence of LVT compared with a reference cardiac imaging (DE-CMR) and to determine the risk of systemic embolization to the CNS using brain MRA.
    Methods: Seventy patients after MI managed by percutaneous coronary intervention (localization: 92.9% anterior wall, 7% other; median age 58.7 years) were initially examined by transthoracic echocardiography (TTE, n=69) with a focus on LVT detection. Patients were then referred for DE-CMR (n=55). Laboratory determination of cardiac markers (Troponin T and NTproBNP) was carried out in all. Brain MRA was performed 1 year apart (n=51).
    Results: The prevalence of LVT detected by echocardiography: (n=11/69, i.e. 15.9%); by DE-CMR: (n=9/55, i.e. 16.7%). Statistically significant parameters to predict the occurrence of LVT after AMI (cut off value): (a) detected by echocardiography: anamnestic data - delay (≥ 5 hours), echocardiographic parameters - left atrial volume index (LAVI≥ 32 mL/m
    Conclusion: Our study confirmed a relatively high prevalence of LVT in the high-risk group of patients with anterior wall STEMI. Due to the low prevalence of thromboembolic complications, no significant association between the LVT detection and the occurrence of a cardioembolic event was demonstrated.
    Language English
    Publishing date 2023-01-08
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 17196-7
    ISSN 1804-7521 ; 1213-8118 ; 0231-5599 ; 0862-481X
    ISSN (online) 1804-7521
    ISSN 1213-8118 ; 0231-5599 ; 0862-481X
    DOI 10.5507/bp.2023.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Bovine arch.

    Spacek, Miloslav / Veselka, Josef

    Archives of medical science : AMS

    2012  Volume 8, Issue 1, Page(s) 166–167

    Language English
    Publishing date 2012-03-19
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2203781-0
    ISSN 1896-9151 ; 1896-9151
    ISSN (online) 1896-9151
    ISSN 1896-9151
    DOI 10.5114/aoms.2012.27297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Microembolization following balloon deflation during proximally protected carotid artery stenting-a potential focus of procedure improvement?

    Spacek, Miloslav / Veselka, Josef

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2014  Volume 83, Issue 7, Page(s) 1185–1186

    MeSH term(s) Angioplasty, Balloon/instrumentation ; Carotid Artery, Internal/physiopathology ; Carotid Stenosis/therapy ; Cerebrovascular Circulation ; Cerebrovascular Disorders/prevention & control ; Embolic Protection Devices ; Female ; Humans ; Male ; Stents
    Language English
    Publishing date 2014-06-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.24969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Composition of carotid artery stenosis and restenosis: A series of patients assessed with intravascular ultrasound and near-infrared spectroscopy.

    Štěchovský, Cyril / Hájek, Petr / Horváth, Martin / Špaček, Miloslav / Veselka, Josef

    International journal of cardiology

    2016  Volume 207, Page(s) 64–66

    MeSH term(s) Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/pathology ; Coronary Angiography/methods ; Humans ; Male ; Multimodal Imaging/methods ; Spectroscopy, Near-Infrared/methods ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2016-03-15
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2016.01.104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Claudication pain in the left arm of a coronary artery bypass graft patient using crutches: Coronary subclavian steal syndrome - a case report.

    Spaček, Miloslav / Veselka, Josef

    The International journal of angiology : official publication of the International College of Angiology, Inc

    2012  Volume 19, Issue 1, Page(s) e41–2

    Abstract: A 77-year-old male former smoker with hypercholesterolemia and diabetes, who underwent coronary artery bypass graft surgery three years before admission and right carotid endarterectomy four years before admission, presented with recent-onset exertional ... ...

    Abstract A 77-year-old male former smoker with hypercholesterolemia and diabetes, who underwent coronary artery bypass graft surgery three years before admission and right carotid endarterectomy four years before admission, presented with recent-onset exertional chest pain. His medical history revealed that the chest pain was preceded by gradually worsening exertional claudication pain in his left arm when he was using crutches. The chest pain was similar to the pain he experienced before the coronary artery bypass graft surgery was performed. Coronary angiography and bypass graft imaging showed significant stenosis of the left subclavian artery proximal to the origin of the left internal mammary artery bypass, decreased flow in the left internal mammary artery with partial retrograde filling from the left anterior descending artery, and severe narrowing of the left vertebral artery with preserved centrifugal flow. Percutaneous stent implantation into the left subclavian artery was performed together with proximal balloon angioplasty of the left vertebral artery. The patient has been symptom free since the stent implantation.
    Language English
    Publishing date 2012-04-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1144390-x
    ISSN 1061-1711
    ISSN 1061-1711
    DOI 10.1055/s-0031-1278360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Obesity paradox in female patients after stent implantation for carotid artery disease.

    Veselka, Josef / Spaček, Miloslav / Homolová, Inge / Zimolová, Petra

    International journal of cardiology

    2014  Volume 172, Issue 3, Page(s) 600–601

    MeSH term(s) Aged ; Blood Vessel Prosthesis Implantation/methods ; Body Mass Index ; Carotid Stenosis/complications ; Carotid Stenosis/epidemiology ; Carotid Stenosis/surgery ; Czech Republic/epidemiology ; Female ; Follow-Up Studies ; Humans ; Incidence ; Male ; Obesity/complications ; Obesity/epidemiology ; Prevalence ; Risk Factors ; Sex Factors ; Stents ; Treatment Outcome
    Language English
    Publishing date 2014-04-01
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2014.01.092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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