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  1. Article ; Online: Classification of chikungunya cases: a proposal.

    Brito, Carlos Alexandre Antunes de / Freitas, André Ricardo Ribas / Said, Rodrigo Fabiano / Falcão, Melissa Barreto / Cunha, Rivaldo Venâncio da / Siqueira, André Machado / Teixeira, Maria Glória / Ribeiro, Guilherme Sousa / Brito, Marina Coelho Moraes de / Cavalcanti, Luciano Pamplona de Góes

    Revista da Sociedade Brasileira de Medicina Tropical

    2020  Volume 53, Page(s) e20200529

    MeSH term(s) Chikungunya Fever/diagnosis ; Chikungunya virus ; Dengue ; Humans
    Language English
    Publishing date 2020-11-25
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0529-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2726: Show issues Location:
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  2. Article ; Online: Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19.

    Falcão, Melissa Barreto / Pamplona de Góes Cavalcanti, Luciano / Filgueiras Filho, Nivaldo Menezes / Antunes de Brito, Carlos Alexandre

    The American journal of tropical medicine and hygiene

    2020  Volume 102, Issue 6, Page(s) 1214–1216

    Abstract: Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe ... ...

    Abstract Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQ during the COVID-19 pandemic, this case alerts us to the potential for HCQ to be associated with hepatotoxicity and the need to monitor liver function during HCQ therapy.
    MeSH term(s) Adult ; Alanine Transaminase/blood ; Aspartate Aminotransferases/blood ; Azithromycin/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/isolation & purification ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Coronavirus Infections/therapy ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/adverse effects ; Liver/diagnostic imaging ; Liver/drug effects ; Liver/pathology ; Liver/virology ; Lung/diagnostic imaging ; Lung/drug effects ; Lung/pathology ; Lung/virology ; Pandemics ; Piperacillin, Tazobactam Drug Combination/therapeutic use ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/therapy ; Respiration, Artificial ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Chemical Substances Piperacillin, Tazobactam Drug Combination (157044-21-8) ; Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5) ; Aspartate Aminotransferases (EC 2.6.1.1) ; Alanine Transaminase (EC 2.6.1.2)
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.20-0276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lipidomic Analysis Reveals Serum Alteration of Plasmalogens in Patients Infected With ZIKA Virus.

    Queiroz, Adriano / Pinto, Isabella Fernanda Dantas / Lima, Maricélia / Giovanetti, Marta / de Jesus, Jaqueline Goes / Xavier, Joilson / Barreto, Fernanda Khouri / Canuto, Gisele André Baptista / do Amaral, Helineide Ramos / de Filippis, Ana Maria Bispo / Mascarenhas, Denise Lima / Falcão, Melissa Barreto / Santos, Normeide Pedreira / Azevedo, Vasco Ariston de Carvalho / Yoshinaga, Marcos Yukio / Miyamoto, Sayuri / Alcantara, Luiz Carlos Junior

    Frontiers in microbiology

    2019  Volume 10, Page(s) 753

    Abstract: Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in ... ...

    Abstract Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the
    Language English
    Publishing date 2019-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2019.00753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Case Report: Hepatotoxicity Associated with the Use of Hydroxychloroquine in a Patient with COVID-19

    Falcão, Melissa Barreto / Pamplona de Góes Cavalcanti, Luciano / Filgueiras Filho, Nivaldo Menezes / Antunes de Brito, Carlos Alexandre

    Am J Trop Med Hyg

    Abstract: Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe ... ...

    Abstract Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease (COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can be associated with its use. Here, we report a case of a patient with severe COVID-19 who, after being administered HCQ, exhibited a 10-fold increase in serum levels of transaminases, followed by a rapid decrease after HCQ was withdrawn. Considering the significantly increased use of HCQ during the COVID-19 pandemic, this case alerts us to the potential for HCQ to be associated with hepatotoxicity and the need to monitor liver function during HCQ therapy.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32314698
    Database COVID19

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  5. Article ; Online: Classification of chikungunya cases

    Carlos Alexandre Antunes de Brito / André Ricardo Ribas Freitas / Rodrigo Fabiano Said / Melissa Barreto Falcão / Rivaldo Venâncio da Cunha / André Machado Siqueira / Maria Glória Teixeira / Guilherme Sousa Ribeiro / Marina Coelho Moraes de Brito / Luciano Pamplona de Góes Cavalcanti

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    a proposal

    2020  Volume 53

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Update on the treatment of musculoskeletal manifestations in chikungunya fever: a guideline.

    Brito, Carlos Alexandre Antunes de / Marques, Cláudia Diniz Lopes / Falcão, Melissa Barreto / Cunha, Rivaldo Venâncio da / Simon, Fabrice / Valadares, Lilian David de Azevedo / Luz, Kleber Giovanni / Melo, Carlos Frederico Campelo de Albuquerque E / Albuquerque Filho, Dalcy de Oliveira / Brito, Marina Coelho Moraes de / Duarte, Angela Luzia Branco Pinto

    Revista da Sociedade Brasileira de Medicina Tropical

    2020  Volume 53, Page(s) e20190517

    Abstract: Since the emergence of the chikungunya virus in Brazil in 2014, more than 700,000 cases have been reported throughout the country, corresponding to one-third of all cases reported in the Americas. In addition to its high attack rates, resulting in ... ...

    Abstract Since the emergence of the chikungunya virus in Brazil in 2014, more than 700,000 cases have been reported throughout the country, corresponding to one-third of all cases reported in the Americas. In addition to its high attack rates, resulting in hundreds of thousands of cases, the disease has high chronicity rates with persistent joint manifestations for more than 3 months, which can spread to more than half of the patients affected in the acute phase. Pain associated with musculoskeletal manifestations, often disabling, has an effect on patients' quality of life at different stages of the disease. Currently, the challenge faced by specialists is identifying the best therapy to be instituted for symptom relief despite the limited number of published intervention studies. In 2016, a multidisciplinary group published pharmacological treatment protocols for pain in patients with chikungunya, which was incorporated into the guidelines for clinical management of the Brazilian Ministry of Health in 2017; in that same year, a consensus was published by the Brazilian Society of Rheumatology about diagnosis and treatment. After 5 years of experience with chikungunya epidemics, in 2019, specialists involved in the protocols of the Brazilian Society of Rheumatology and Brazilian Ministry of Health prepared an update with the main objective of developing flowcharts for the therapeutic approach of musculoskeletal manifestations in adult patients to enable specialists at different levels of healthcare to spread and apply this guideline in a systematic and simplified manner.
    MeSH term(s) Adult ; Brazil ; Chikungunya Fever/complications ; Chikungunya Fever/diagnosis ; Chikungunya Fever/therapy ; Consensus ; Humans ; Quality of Life ; Rheumatology
    Language English
    Publishing date 2020-07-31
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0517-2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole: a case report.

    Hagan, José Edward / Dias, Jesângeli Sousa / Villasboas-Bisneto, José Caetano / Falcão, Melissa Barreto / Ko, Albert Icksang / Ribeiro, Guilherme Sousa

    Revista da Sociedade Brasileira de Medicina Tropical

    2014  Volume 47, Issue 2, Page(s) 254–256

    Abstract: Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV- ... ...

    Abstract Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
    MeSH term(s) Adult ; Antifungal Agents/therapeutic use ; Female ; Fluconazole/therapeutic use ; Humans ; Magnetic Resonance Imaging ; Meningitis, Cryptococcal/diagnosis ; Meningitis, Cryptococcal/drug therapy ; Puerperal Infection/diagnosis ; Puerperal Infection/drug therapy
    Chemical Substances Antifungal Agents ; Fluconazole (8VZV102JFY)
    Language English
    Publishing date 2014-05-27
    Publishing country Brazil
    Document type Case Reports ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0215-2013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2726: Show issues Location:
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  8. Article ; Online: Update on the treatment of musculoskeletal manifestations in chikungunya fever

    Carlos Alexandre Antunes de Brito / Cláudia Diniz Lopes Marques / Melissa Barreto Falcão / Rivaldo Venâncio da Cunha / Fabrice Simon / Lilian David de Azevedo Valadares / Kleber Giovanni Luz / Carlos Frederico Campelo de Albuquerque e Melo / Dalcy de Oliveira Albuquerque Filho / Marina Coelho Moraes de Brito / Angela Luzia Branco Pinto Duarte

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    a guideline

    2020  Volume 53

    Abstract: Abstract Since the emergence of the chikungunya virus in Brazil in 2014, more than 700,000 cases have been reported throughout the country, corresponding to one-third of all cases reported in the Americas. In addition to its high attack rates, resulting ... ...

    Abstract Abstract Since the emergence of the chikungunya virus in Brazil in 2014, more than 700,000 cases have been reported throughout the country, corresponding to one-third of all cases reported in the Americas. In addition to its high attack rates, resulting in hundreds of thousands of cases, the disease has high chronicity rates with persistent joint manifestations for more than 3 months, which can spread to more than half of the patients affected in the acute phase. Pain associated with musculoskeletal manifestations, often disabling, has an effect on patients’ quality of life at different stages of the disease. Currently, the challenge faced by specialists is identifying the best therapy to be instituted for symptom relief despite the limited number of published intervention studies. In 2016, a multidisciplinary group published pharmacological treatment protocols for pain in patients with chikungunya, which was incorporated into the guidelines for clinical management of the Brazilian Ministry of Health in 2017; in that same year, a consensus was published by the Brazilian Society of Rheumatology about diagnosis and treatment. After 5 years of experience with chikungunya epidemics, in 2019, specialists involved in the protocols of the Brazilian Society of Rheumatology and Brazilian Ministry of Health prepared an update with the main objective of developing flowcharts for the therapeutic approach of musculoskeletal manifestations in adult patients to enable specialists at different levels of healthcare to spread and apply this guideline in a systematic and simplified manner.
    Keywords Chikungunya fever ; Musculoskeletal pain ; Arbovirus ; Management ; Arctic medicine. Tropical medicine ; RC955-962
    Subject code 616
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole

    José Edward Hagan / Jesângeli Sousa Dias / José Caetano Villasboas-Bisneto / Melissa Barreto Falcão / Albert Icksang Ko / Guilherme Sousa Ribeiro

    Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 2, Pp 254-

    a case report

    2014  Volume 256

    Abstract: Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV- ... ...

    Abstract Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
    Keywords Cryptococcus ; Immune reconstitution inflammatory syndrome ; Treatment ; Medicine (General) ; R5-920 ; Medicine ; R
    Language Portuguese
    Publishing date 2014-04-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical - SBMT
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article ; Online: Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole

    José Edward Hagan / Jesângeli Sousa Dias / José Caetano Villasboas-Bisneto / Melissa Barreto Falcão / Albert Icksang Ko / Guilherme Sousa Ribeiro

    Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 2, Pp 254-

    a case report

    2014  Volume 256

    Abstract: Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV- ... ...

    Abstract Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
    Keywords Cryptococcus ; Immune reconstitution inflammatory syndrome ; Treatment ; Medicine (General) ; R5-920 ; Medicine ; R
    Language Portuguese
    Publishing date 2014-04-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical - SBMT
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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