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  1. Article ; Online: Layered dermal reconstitution through epigallocatechin 3-gallate loaded chitosan nanoparticle within enzymatically crosslinked polyvinyl alcohol/collagen fibrous mat.

    Badali, Elham / Goodarzi, Arash / Khodayari, Hamid / Khodayari, Saeed / Habibi, Azizollah / Hasanzadeh, Sajad / Khanmohammadi, Mehdi

    Journal of biomaterials applications

    2022  Volume 37, Issue 3, Page(s) 502–516

    Abstract: Biocompatible electrospun fiber comprising bioactive substrates has potential to implant into the wound site as a reliable therapeutic approach in tissue regeneration. Here, electrospun polyvinyl alcohol conjugated tyramine (PVA-Tyr) and collagen (Col) ... ...

    Abstract Biocompatible electrospun fiber comprising bioactive substrates has potential to implant into the wound site as a reliable therapeutic approach in tissue regeneration. Here, electrospun polyvinyl alcohol conjugated tyramine (PVA-Tyr) and collagen (Col) fibrous mat containing chitosan nanoparticle loaded with epigallocatechin 3-gallate (NCs-EGCG) developed and the composite was applied to evaluate in vivo wound healing ability of fabricated wound patch. The synthesized PVA-Tyr and Col were electrospun and crosslinked through peroxidase reaction in presence of vaporized H
    MeSH term(s) Animals ; Catechin/analogs & derivatives ; Chitosan/chemistry ; Collagen ; Hydrogen Peroxide ; Nanoparticles ; Polyvinyl Alcohol/chemistry
    Chemical Substances Catechin (8R1V1STN48) ; Polyvinyl Alcohol (9002-89-5) ; Collagen (9007-34-5) ; Chitosan (9012-76-4) ; Hydrogen Peroxide (BBX060AN9V) ; gallocatechol (HEJ6575V1X)
    Language English
    Publishing date 2022-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 639283-0
    ISSN 1530-8022 ; 0885-3282
    ISSN (online) 1530-8022
    ISSN 0885-3282
    DOI 10.1177/08853282221104175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identification and detection of pathogenic bacteria from patients with hospital-acquired pneumonia in southwestern Iran; evaluation of biofilm production and molecular typing of bacterial isolates.

    Mazloomirad, Farzad / Hasanzadeh, Sajad / Sharifi, Asghar / Nikbakht, Gordafarin / Roustaei, Narges / Khoramrooz, Seyed Sajjad

    BMC pulmonary medicine

    2021  Volume 21, Issue 1, Page(s) 408

    Abstract: Background: Hospital-acquired pneumonia (HAP) is the second most common nosocomial infection in intensive care units (ICUs). The present study aims to determine the prevalence of pathogenic bacteria, their biofilm formation, and molecular typing from ... ...

    Abstract Background: Hospital-acquired pneumonia (HAP) is the second most common nosocomial infection in intensive care units (ICUs). The present study aims to determine the prevalence of pathogenic bacteria, their biofilm formation, and molecular typing from patients with HAP in southwestern Iran.
    Methods: Fifty-eight patients with HAP participated in this cross-sectional study. Sputum and endotracheal aspirate were collected from each patient for isolation and detection of bacteria. Biofilm formation was evaluated using Congo red agar or Microtiter plate assay. The antimicrobial susceptibility patterns of the isolates were investigated. The multiplex polymerase chain reaction (M-PCR) technique was used to determine the Staphylococcal Cassette Chromosome mec (SCCmec) types of methicillin-resistant Staphylococcus aureus (MRSA) strains. All S. aureus isolates were typed using the agr typing method. A repetitive element sequence-based PCR (rep-PCR) typing method was used for typing of Gram-negative bacteria. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software version 15 and the chi-square test.
    Results: Bacteria were isolated in 52 (89.7%) of patients. Acinetobacter baumannii (A. baumannii) was the most prevalent organism (37%), followed by S. aureus, Pseudomonas aeruginosa (P. aeruginosa), and Escherichia coli (E. coli). Using the PCR method, 56 bacteria were detected. A. baumannii was the most prevalent (35.7%) organism. A. baumannii and P. aeruginosa were biofilm-producing. All Gram-negative isolates were colistin-sensitive, and most of the A. baumannii isolates were multidrug-resistant (MDR). MRSA was identified in 12 (80%) S. aureus isolates, and 91.6% of MRSA were SCCmec type III. The agr type III was the most predominant. The rep-PCR analysis showed seven different patterns in 20 A. baumannii, six patterns in 13 P. aeruginosa, and four patterns in 6 E. coli.
    Conclusion: A. baumannii was more prevalent than S. aureus in ventilator-associated pneumonia (VAP), while S. aureus is a major pathogen in non-ventilator hospital-acquired pneumonia (NV-HAP), possibly due to the tendency of the former to aquatic environments. Based on the rep-PCR typing method, it was concluded that bacteria were transmitted from patients or healthcare workers among different wards. Colistin can be used as a treatment in Gram-negative MDR isolates.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biofilms ; Cross-Sectional Studies ; Female ; Gram-Negative Bacteria/genetics ; Gram-Negative Bacteria/isolation & purification ; Gram-Negative Bacterial Infections/epidemiology ; Gram-Positive Bacteria/genetics ; Gram-Positive Bacteria/isolation & purification ; Gram-Positive Bacterial Infections/epidemiology ; Healthcare-Associated Pneumonia/epidemiology ; Healthcare-Associated Pneumonia/microbiology ; Humans ; Iran/epidemiology ; Male ; Middle Aged ; Polymerase Chain Reaction ; Young Adult
    Language English
    Publishing date 2021-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-021-01773-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A fractional-order model for the novel coronavirus (COVID-19) outbreak.

    Rajagopal, Karthikeyan / Hasanzadeh, Navid / Parastesh, Fatemeh / Hamarash, Ibrahim Ismael / Jafari, Sajad / Hussain, Iqtadar

    Nonlinear dynamics

    2020  Volume 101, Issue 1, Page(s) 711–718

    Abstract: The outbreak of the novel coronavirus (COVID-19), which was firstly reported in China, has affected many countries worldwide. To understand and predict the transmission dynamics of this disease, mathematical models can be very effective. It has been ... ...

    Abstract The outbreak of the novel coronavirus (COVID-19), which was firstly reported in China, has affected many countries worldwide. To understand and predict the transmission dynamics of this disease, mathematical models can be very effective. It has been shown that the fractional order is related to the memory effects, which seems to be more effective for modeling the epidemic diseases. Motivated by this, in this paper, we propose fractional-order susceptible individuals, asymptomatic infected, symptomatic infected, recovered, and deceased (SEIRD) model for the spread of COVID-19. We consider both classical and fractional-order models and estimate the parameters by using the real data of Italy, reported by the World Health Organization. The results show that the fractional-order model has less root-mean-square error than the classical one. Finally, the prediction ability of both of the integer- and fractional-order models is evaluated by using a test data set. The results show that the fractional model provides a closer forecast to the real data.
    Keywords covid19
    Language English
    Publishing date 2020-06-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012600-1
    ISSN 1573-269X ; 0924-090X
    ISSN (online) 1573-269X
    ISSN 0924-090X
    DOI 10.1007/s11071-020-05757-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Case Report: Polyarteritis nodosa or complicated Henoch-Schonlein purpura (IgAV), a rare case.

    Hasanzadeh, Sajad / Alavi, Seyedeh Maryam / Masnavi, Elahe / Jokar, Saeid / Rohani, Maryam

    F1000Research

    2018  Volume 7, Page(s) 49

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2018-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.13295.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis.

    Jafari, Behnam / Sabz, Gholamabas / Masnavi, Elahe / Panahi, Roghaye / Jokar, Saeid / Roozbehi, Amrollah / Hasanzadeh, Sajad

    F1000Research

    2018  Volume 7, Page(s) 288

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2018-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.13787.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Repetitive transcranial magnetic stimulation: a potential therapeutic modality for chronic low back pain.

    Shafiee, Sajad / Hasanzadeh Kiabi, Farshad / Shafizad, Misagh / Emami Zeydi, Amir

    The Korean journal of pain

    2016  Volume 30, Issue 1, Page(s) 71–72

    Language English
    Publishing date 2016-12-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2558899-0
    ISSN 2093-0569 ; 2005-9159
    ISSN (online) 2093-0569
    ISSN 2005-9159
    DOI 10.3344/kjp.2017.30.1.71
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  7. Article: Patients with Covid 19 have significantly reduced CH50 activity.

    Keshavarz, Fatemeh / Ghalamfarsa, Farideh / Javdansirat, Saeed / Hasanzadeh, Sajad / Azizi, Arsalan / Sabz, Gholamabbas / Salehi, Marziyeh / Ghalamfarsa, Ghasem

    Virusdisease

    2021  Volume 32, Issue 4, Page(s) 681–689

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a new virus that emerged in China and immediately spread around the world. Evidence has been documented that the immune system is ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a new virus that emerged in China and immediately spread around the world. Evidence has been documented that the immune system is impressively involved in the pathogenesis of this disease, especially in causing inflammation. One of the important components of the immune system is the complement system whose increased activity has been shown in inflammatory diseases and consequently damage caused by the activity of its components. In the present study, serum levels of C3 and C4 factors as well as the activity level of complement system in the classical pathway were measured by CH50 test in patients with SARS-CoV-2. Participants in the study consisted of 53 hospitalized patients whose real-time PCR test was positive for SARS-CoV-2. The mean age of these patients was 42.06 ± 18.7 years, including 40% women and 60% men. The most common symptoms in these patients were cough (70%), fever (59%), dyspnea (53%) and chills (53%), respectively. Analysis of biochemical and hematological test results revealed that 26 (49%) patients had lymphopenia, 34 (64%) patients were positive for C-reactive protein (CRP) and 26 (49%) patients had ESR and LDH levels significantly higher than normal. In addition, 27 patients (51%) had vitamin D deficiency. The mean CH50 activity level in COVID-19 patients was significantly reduced compared to healthy individuals (84.9 versus 169.9 U/ml,
    Language English
    Publishing date 2021-10-02
    Publishing country India
    Document type Journal Article
    ZDB-ID 2846993-8
    ISSN 2347-3517 ; 2347-3584
    ISSN (online) 2347-3517
    ISSN 2347-3584
    DOI 10.1007/s13337-021-00710-6
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  8. Article ; Online: A fractional-order model for the novel coronavirus (COVID-19) outbreak

    Rajagopal, Karthikeyan / Hasanzadeh, Navid / Parastesh, Fatemeh / Hamarash, Ibrahim Ismael / Jafari, Sajad / Hussain, Iqtadar

    Nonlinear Dynamics

    2020  Volume 101, Issue 1, Page(s) 711–718

    Keywords Control and Systems Engineering ; Mechanical Engineering ; Electrical and Electronic Engineering ; Applied Mathematics ; Ocean Engineering ; Aerospace Engineering ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2012600-1
    ISSN 1573-269X ; 0924-090X
    ISSN (online) 1573-269X
    ISSN 0924-090X
    DOI 10.1007/s11071-020-05757-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Patients with Covid 19 have significantly reduced CH50 activity

    Keshavarz, Fatemeh / Ghalamfarsa, Farideh / Javdansirat, Saeed / Hasanzadeh, Sajad / Azizi, Arsalan / Sabz, Gholamabbas / Salehi, Marziyeh / Ghalamfarsa, Ghasem

    Virusdisease. 2021 Dec., v. 32, no. 4

    2021  

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a new virus that emerged in China and immediately spread around the world. Evidence has been documented that the immune system is ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a new virus that emerged in China and immediately spread around the world. Evidence has been documented that the immune system is impressively involved in the pathogenesis of this disease, especially in causing inflammation. One of the important components of the immune system is the complement system whose increased activity has been shown in inflammatory diseases and consequently damage caused by the activity of its components. In the present study, serum levels of C3 and C4 factors as well as the activity level of complement system in the classical pathway were measured by CH50 test in patients with SARS-CoV-2. Participants in the study consisted of 53 hospitalized patients whose real-time PCR test was positive for SARS-CoV-2. The mean age of these patients was 42.06 ± 18.7 years, including 40% women and 60% men. The most common symptoms in these patients were cough (70%), fever (59%), dyspnea (53%) and chills (53%), respectively. Analysis of biochemical and hematological test results revealed that 26 (49%) patients had lymphopenia, 34 (64%) patients were positive for C-reactive protein (CRP) and 26 (49%) patients had ESR and LDH levels significantly higher than normal. In addition, 27 patients (51%) had vitamin D deficiency. The mean CH50 activity level in COVID-19 patients was significantly reduced compared to healthy individuals (84.9 versus 169.9 U/ml, p = < 0.0001). Comparison of the mean CH50 activity levels between different subgroups of patients indicated that COVID-19 patients with decreased peripheral blood lymphocyte count and positive CRP had a significant increase in activity compared to the other groups (p = 0.0002). The serum levels of C3 and C4 factors had no significant change between patients and healthy individuals. Conclusion: The activity level of complement system in the classical pathway decreases in COVID-19 patients compared to healthy individuals, due to increased activity of complement system factors in these patients.
    Keywords C-reactive protein ; COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; blood serum ; complement ; cough ; dyspnea ; fever ; immune system ; inflammation ; lymphocyte count ; pathogenesis ; quantitative polymerase chain reaction ; viruses ; China
    Language English
    Dates of publication 2021-12
    Size p. 681-689.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2846993-8
    ISSN 2347-3517 ; 2347-3584
    ISSN (online) 2347-3517
    ISSN 2347-3584
    DOI 10.1007/s13337-021-00710-6
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  10. Article: Epstein-Barr virus hepatitis can cause transient hepatopulmonary syndrome.

    Ghayumi, Seiyed Mohammad Ali / Rohani, Maryam / Hasanzadeh, Sajad / Sadeghi, Shahrokh / Roozbehi, Amrollah / Jokar, Saeid

    Respiratory medicine case reports

    2018  Volume 24, Page(s) 50–51

    Abstract: Introduction: Hepatopulmonary syndrome is commonly seen in the patients with chronic liver disease. Acute liver diseases are rarely associated with HPS. We have reported here a case of Transient HPS caused by Epstein-Barr virus hepatitis.: Case report! ...

    Abstract Introduction: Hepatopulmonary syndrome is commonly seen in the patients with chronic liver disease. Acute liver diseases are rarely associated with HPS. We have reported here a case of Transient HPS caused by Epstein-Barr virus hepatitis.
    Case report: The patient was a 31 years old man that came to hospital due to RUQ pain and yellowish skin. In examination the patient was tachypnic and O2 saturation was 71% with prominent JVP. ver enzyme and bilirubin were high. All viral hepatitis was negative except anti viral capsid antigen-antibody of EBV. In Blood gas PaO2 was 54 mmHg, O2 saturation 73% and alveolar-arterial gradient was 18 mmHg. Stress Echocardiography with saline injection reported pulmonary arterial pressure 32 cmHg with delayed opacification of left atrium.
    Conclusion: transient HPS can be manifestation in the acute hepatitis caused by EBV infection.
    Language English
    Publishing date 2018-04-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 2666110-X
    ISSN 2213-0071
    ISSN 2213-0071
    DOI 10.1016/j.rmcr.2018.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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