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  1. Article: Population genetic assessment of

    Zhu, Hong / Liu, Juan / Gao, Meirong / Yue, Chunlei / Li, Hepeng

    Frontiers in genetics

    2023  Volume 14, Page(s) 1150437

    Abstract: ... Viburnum ... ...

    Abstract Viburnum japonicum
    Language English
    Publishing date 2023-06-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1150437
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  2. Article ; Online: IL1A regulates the inflammation in gout through the Toll-like receptors pathway.

    Ling, Meirong / Gan, Jiaqi / Hu, Mengting / Pan, Fei / Liu, Mei

    International journal of medical sciences

    2024  Volume 21, Issue 1, Page(s) 188–199

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Leukocytes, Mononuclear/metabolism ; Interleukin-1alpha/metabolism ; Gout/genetics ; Gout/complications ; Uric Acid ; Inflammation/metabolism ; Toll-Like Receptors/genetics ; Toll-Like Receptors/metabolism
    Chemical Substances Interleukin-1alpha ; Uric Acid (268B43MJ25) ; Toll-Like Receptors ; IL1A protein, human
    Language English
    Publishing date 2024-01-01
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2151424-0
    ISSN 1449-1907 ; 1449-1907
    ISSN (online) 1449-1907
    ISSN 1449-1907
    DOI 10.7150/ijms.88447
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  3. Article ; Online: Urbanization, economic agglomeration and economic growth

    Yejin Liu / Meirong Yang / Jiahui Cui

    Heliyon, Vol 10, Iss 1, Pp e23772- (2024)

    1481  

    Abstract: Are Chinese cities too agglomerated, and are production factors continuing to flow to cities?In recent years, research on this issue has attracted more and more attention from academics, for the research on this issue, academics generally believe that ... ...

    Abstract Are Chinese cities too agglomerated, and are production factors continuing to flow to cities?In recent years, research on this issue has attracted more and more attention from academics, for the research on this issue, academics generally believe that urbanization has a positive role in promoting economic growth, but whether urbanization will bring economic agglomeration and what is the role of economic agglomeration on the development of the economy? The research on this issue is still insufficient, therefore, Based on the panel data of 27 provinces from 2006 to 2020, it is generally believed that urbanization has a positive role in promoting economic growth. This paper adds economic agglomeration factors and uses a spatial econometric model to test the spillover effect of urbanization growth. The main conclusions are as follows: First, urbanization and economic agglomeration have a positive effect on economic growth, and there is a spatial spillover effect. Secondly, the advancement of urbanization is closely associated with economic growth, particularly in relation to the development of economic agglomeration. When economic agglomeration is based on a single-center model, it tends to impede urbanization and economic progress. In contrast, an economic agglomeration model with multiple centers has the potential to stimulate urbanization and further enhance economic growth. Thirdly, it is worth noting that the influence of urbanization on economic growth varies across different regions. Factors such as geographical location, resource availability, and local economic conditions contribute to this regional variation.
    Keywords Urbanization ; Economic agglomeration ; Economic growth ; Spillover effect ; Nighttime lighting data ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 339
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Predictive value of immediate early response 5 like (IER5L) in the prognosis and immune checkpoint blockade therapy of non-small cell lung cancer patients.

    Wang, Nana / Tan, Xiaofeng / Cao, Shuming / Liu, Meirong

    Pathology, research and practice

    2024  Volume 256, Page(s) 155270

    Abstract: Background: Non-small cell lung cancer (NSCLC) is a malignancy with high mortality. Immediate early response 5 like (IER5L) has been found to associate with worse prognosis in colorectal cancer patients. However, its role in the prognosis prediction of ... ...

    Abstract Background: Non-small cell lung cancer (NSCLC) is a malignancy with high mortality. Immediate early response 5 like (IER5L) has been found to associate with worse prognosis in colorectal cancer patients. However, its role in the prognosis prediction of NSCLC has remained largely unknown.
    Methods: The IER5L expression in NSCLC and normal tissues was analyzed in two public cohorts: TCGA-LUAD-LUSC and GSE159857. Additionally, functional enrichment, survival analysis, CIBERSORT and tumor mutation burden (TMB) were investigated between low- and high-IER5L level groups. The in vitro IER5L mRNA and protein levels were determined using RT-qPCR and western blot, respectively.
    Results: The data from TCGA-LUAD-LUSC and GSE159857 cohorts showed a high IER5L mRNA expression in NSCLC tissue samples compared to normal controls. The increased expression of IER5L in NSCLC cells were also validated by RT-qPCR and western blot analysis. Additionally, NSCLC patients with high-IER5L level had significantly worse prognosis and IER5L could be used as an independent prognostic factor for NSCLC patients. Meanwhile, patients in the high-IER5L group had higher TMB level. IER5L expression was negatively correlated with the proportion of Monocytes and T cells CD4 memory resting, and was positively related to the proportion of Tregs and M0 macrophages in tumor tissues. Besides, transcription factors TFAP4 and ZNF692 may bind to the promoter region of IER5L, and then modulate IER5L gene transcription, thereby affecting IER5L gene expression. Furthermore, GSEA results showed that IER5L gene was closely related to MAPK, PI3K-Akt, NF-kappaB signaling pathways in NSCLC.
    Conclusion: Collectively, high IER5L expression may be a promising unfavorable prognostic biomarker and therapeutic target for NSCLC patients.
    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung/genetics ; Immune Checkpoint Inhibitors ; Phosphatidylinositol 3-Kinases ; Lung Neoplasms/genetics ; Prognosis ; RNA, Messenger ; DNA-Binding Proteins ; Transcription Factors
    Chemical Substances Immune Checkpoint Inhibitors ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; RNA, Messenger ; ZNF692 protein, human ; DNA-Binding Proteins ; Transcription Factors
    Language English
    Publishing date 2024-03-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2024.155270
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    In stock of ZB MED Cologne/Königswinter

    Ud III Zs.20: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article: Variation of endosymbiont and

    Cui, Xiaoqing / Liu, Yangyang / Zhang, Jingtian / Hu, Panpan / Zheng, Zheng / Deng, Xiaoling / Xu, Meirong

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1236731

    Abstract: ...

    Abstract "
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1236731
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  6. Article ; Online: A viral protein competitively bound to rice CIPK23 inhibits potassium absorption and facilitates virus systemic infection in rice.

    Jing, Xinxin / Wang, Pengyue / Liu, Jianjian / Xiang, Meirong / Song, Xia / Wang, Chaonan / Li, Pengbai / Li, Honglian / Wu, Zujian / Zhang, Chao

    Plant biotechnology journal

    2024  

    Abstract: Potassium ( ... ...

    Abstract Potassium (K
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2136367-5
    ISSN 1467-7652 ; 1467-7652
    ISSN (online) 1467-7652
    ISSN 1467-7652
    DOI 10.1111/pbi.14350
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  7. Article ; Online: Catalytic Coupling of Free Radical Oxidation and Electrophilic Chlorine Addition by Phase-Transfer Intermediates in Liquid Aerosols.

    Zeng, Meirong / Liu, Chen-Lin / Wilson, Kevin R

    The journal of physical chemistry. A

    2022  Volume 126, Issue 19, Page(s) 2959–2965

    Abstract: While examining the heterogeneous reaction of chlorine atoms with alkenes, in the presence of ... ...

    Abstract While examining the heterogeneous reaction of chlorine atoms with alkenes, in the presence of Cl
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c00291
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  8. Article ; Online: Autoimmune hepatitis following COVID-19 vaccination: Clinical characteristics of 35 reported cases.

    Wang, Meirong / Qi, Juan / Liu, Yujuan

    Drug discoveries & therapeutics

    2023  Volume 17, Issue 3, Page(s) 177–182

    Abstract: The coronavirus disease 2019 (COVID-19) vaccines have been shown to be effective in protecting people from severe disease progression, hospitalisation and death. However, a wide range of side effects have been reported worldwide. New onset or flare-up of ...

    Abstract The coronavirus disease 2019 (COVID-19) vaccines have been shown to be effective in protecting people from severe disease progression, hospitalisation and death. However, a wide range of side effects have been reported worldwide. New onset or flare-up of autoimmune hepatitis (AIH) is an extremely rare adverse event following COVID-19 vaccination, with the majority of cases presenting with mild symptoms. Unfortunately, there have been cases of fatal complications. In this mini-review, we have summarised the clinical characteristics of a total of 35 currently reported cases of AIH after COVID-19 vaccination and suggest that patients with autoimmune diseases may be at higher risk of developing AIH after vaccination.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/complications ; COVID-19 Vaccines/adverse effects ; Hepatitis, Autoimmune/etiology ; Hepatitis, Autoimmune/diagnosis ; Hepatitis, Autoimmune/drug therapy ; Vaccination/adverse effects ; Case Reports as Topic
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-06-16
    Publishing country Japan
    Document type Review ; Journal Article
    ZDB-ID 2568828-5
    ISSN 1881-784X ; 1881-784X
    ISSN (online) 1881-784X
    ISSN 1881-784X
    DOI 10.5582/ddt.2023.01022
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  9. Article ; Online: Exploration of Sweeping Effect: Droplet Coalescence Jumping of a Rolling and Static Droplet.

    Liu, Chuntian / Zhao, Meirong / Guo, Jinwei / Zhang, Shiyu / Song, Le / Zheng, Yelong

    Langmuir : the ACS journal of surfaces and colloids

    2024  Volume 40, Issue 4, Page(s) 2278–2287

    Abstract: The sweeping effect of merged droplets plays a key role in enhancing application performance due to the continuing coalescence caused by the horizontal jumping velocity. Most studies focused on static droplet coalescence jumping, while moving droplet ... ...

    Abstract The sweeping effect of merged droplets plays a key role in enhancing application performance due to the continuing coalescence caused by the horizontal jumping velocity. Most studies focused on static droplet coalescence jumping, while moving droplet coalescence is poorly understood. In this work, we experimentally and numerically study the coalescence of a rolling droplet and a static one. When the droplet radius ratio is larger than 0.8, as the dimensionless initial velocity increases and the vertical jumping velocity first decreases and then increases. The critical dimensionless initial velocity
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c03364
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  10. Article ; Online: Diagnosis of multiple tuberculous muscle abscesses in a patient with systemic lupus erythematosus by metagenomic next-generation sequencing- a case report and literature review.

    Wentao, Liu / Shuxia, Xie / Guoxing, Zhu / Qiaoping, Chen / Peiran, Chen / Angela, Wu / Meirong, Li / Songchao, Yin / Peiying, Feng

    BMC infectious diseases

    2024  Volume 24, Issue 1, Page(s) 284

    Abstract: Background: Early diagnosis of muscular tuberculosis (TB) without coexistent active skeletal involvement is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and ... ...

    Abstract Background: Early diagnosis of muscular tuberculosis (TB) without coexistent active skeletal involvement is often challenging because the disease is very rare and its clinical manifestation is nonspecific and misleading. To raise the awareness and emphasize early diagnosis of muscular TB, we present a case of multiple tuberculous muscle abscesses in a systemic lupus erythematosus (SLE) female, but without pulmonary tuberculosis (PTB), in order to increase awareness of and stress the need of early detection of muscular TB.
    Case presentation: A 44-year-old woman with a 6-year history of SLE who had been treated with methylprednisolone for a long time complained of erythema on her trunk and extremities for five months, along with edema and myalgia for two months, and fever for one month. The patient was first misdiagnosed as SLE overlap dermatomyositis. However, an ultrasound-guided drainage of muscle abscesses revealed positive acid-fast staining combined with positive deoxyribonucleic acid fragment of Mycobacterium tuberculosis using metagenomic next-generation sequencing (mNGS). The patient was cured and released following standard anti-tuberculosis medication, local puncture drainage, and an intravitreal injection of streptomycin. Literature search found only 19 cases of tuberculous muscle abscesses occurring in the extremities reported from 1999 to 2023.
    Conclusions: Extrapulmonary TB with predominantly muscle involvement is rare and with no specific clinical presentation. Muscular tuberculosis may be disdiagnosed for dermatomyositis due to the high muscle enzyme levels, delaying diagnosis and treatment. mNGS technology is helpful in the early and rapid diagnosis of muscular TB. On the basis of traditional anti-tuberculosis treatment, an ultrasound-guided percutaneous puncture drainage and intracavitary injection of streptomycin for the treatment of tuberculous muscle abscess is easy to operate, safe and effective, which is worthy of clinical popularization and application.
    MeSH term(s) Female ; Humans ; Adult ; Abscess/diagnosis ; Dermatomyositis/complications ; Dermatomyositis/diagnosis ; Muscles ; Tuberculosis/complications ; Tuberculosis/diagnosis ; Tuberculosis/drug therapy ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; High-Throughput Nucleotide Sequencing ; Streptomycin
    Chemical Substances Streptomycin (Y45QSO73OB)
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-024-09179-2
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