LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 367

Search options

  1. Book ; Conference proceedings: James Frazer Stirling

    Stirling, James Frazer / Vidler, Anthony

    notes from the archive ; [accompanies the Exhibition 'Notes from the Archive: James Frazer Stirling', on view at the Yale Center for British Art, New Haven (14 October 2010 - 2 January 2011), Tate Britain (Spring/Summer 2011), Staatsgalerie Stuttgart (October - January 2012), and the Canadian Centre for Architecture, Montreal (May - October 2012), Staatsgalerie Stuttgart ...]

    2010  

    Title variant James Frazer Stirling - notes from the archive ; Notes from the archive
    Institution James Stirling, Michael Wilford, and Associates
    Canadian Centre for Architecture
    Exhibition Notes from the Archive: James Frazer Stirling
    Staatsgalerie Stuttgart
    Tate Britain
    Yale Center for British Art
    Event/congress Ausstellung (2011.10.01-2012.01.15, Stuttgart) ; Exhibition 'Notes from the Archive: James Frazer Stirling' (2010.10.14-2011.01.02, NewHavenConn.) ; Exhibition 'Notes from the Archive: James Frazer Stirling' (2011, London) ; Exhibition 'Notes from the Archive: James Frazer Stirling' (2011.10.-2012.01, Stuttgart) ; Exhibition 'Notes from the Archive: James Frazer Stirling' (2012.05.-10, Montreal)
    Author's details Anthony Vidler. Canadian Center for Architecture; Yale Center for British Art
    Language English
    Size 303 S, zahlr. Ill
    Publisher Canadian Center for Architecture ; Yale Center for British Art in assoc. with Yale University Press
    Publishing place Montréal ; New Haven, Conn. u.a.
    Document type Book ; Conference proceedings
    Note Literaturangaben
    ISBN 9780300167238 ; 0300167237
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online: Autoantibodies in Kidney Diseases

    James Marchbank, Kevin / Patton Dixon, Bradley / Dragon-Durey, Marie-Agnes / Frazer-Abel, Ashley / Frazer-Abel, Ashley

    2020  

    Keywords Medicine ; Immunology ; autoantibody (aAb) ; complement ; aHUS ; C3G ; lupus ; immune complex ; IgAN pathogenesis ; nephrology
    Size 1 electronic resource (131 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231571
    ISBN 9782889661527 ; 2889661520
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Notes of a Case of Anencephalous Fœtus.

    Frazer, James C

    Transactions. Edinburgh Obstetrical Society

    2018  Volume 2, Page(s) 364–366

    Language English
    Publishing date 2018-04-03
    Publishing country Scotland
    Document type Journal Article
    ISSN 0269-3402
    ISSN 0269-3402
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Oral iron therapy: Current concepts and future prospects for improving efficacy and outcomes.

    Ebea-Ugwuanyi, Pearl O / Vidyasagar, Sadasivan / Connor, James R / Frazer, David M / Knutson, Mitchell D / Collins, James F

    British journal of haematology

    2024  Volume 204, Issue 3, Page(s) 759–773

    Abstract: Iron deficiency (ID) and iron-deficiency anaemia (IDA) are global public health concerns, most commonly afflicting children, pregnant women and women of childbearing age. Pathological outcomes of ID include delayed cognitive development in children, ... ...

    Abstract Iron deficiency (ID) and iron-deficiency anaemia (IDA) are global public health concerns, most commonly afflicting children, pregnant women and women of childbearing age. Pathological outcomes of ID include delayed cognitive development in children, adverse pregnancy outcomes and decreased work capacity in adults. IDA is usually treated by oral iron supplementation, typically using iron salts (e.g. FeSO
    MeSH term(s) Adult ; Child ; Female ; Humans ; Pregnancy ; Iron/metabolism ; Anemia, Iron-Deficiency/therapy ; Iron Deficiencies ; Iron Overload/drug therapy
    Chemical Substances Iron (E1UOL152H7)
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.19268
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.182: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book: James George Frazer, 1854-1941

    Marett, R. R / Frazer, James George

    1942  

    MeSH term(s) Natural Science Disciplines
    Language English
    Size 17, [1] p., front. (port.), 26 cm.
    Publisher H. Milford
    Publishing place London
    Document type Book
    Note Signed: R.R. Marett. ; "From the Proceedings of the British Academy. Vol. XXVII."
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicity.

    Wright, Quentin G / Sinha, Debottam / Wells, James W / Frazer, Ian H / Gonzalez Cruz, Jazmina L / Leggatt, Graham Robert

    Journal for immunotherapy of cancer

    2024  Volume 12, Issue 1

    Abstract: Background: Skin cancers, particularly keratinocyte cancers, are the most commonly diagnosed tumors. Although surgery is often effective in early-stage disease, skin tumors are not always easily accessible, can reoccur and have the ability to ... ...

    Abstract Background: Skin cancers, particularly keratinocyte cancers, are the most commonly diagnosed tumors. Although surgery is often effective in early-stage disease, skin tumors are not always easily accessible, can reoccur and have the ability to metastasize. More recently, immunotherapies, including intravenously administered checkpoint inhibitors, have been shown to control some skin cancers, but with off-target toxicities when used in combination. Our study investigated whether peritumoral administration of an antibody combination targeting PD-1, 4-1BB (CD137) and VISTA might control skin tumors and lead to circulating antitumor immunity without off-target toxicity.
    Methods: The efficacy of combination immunotherapy administered peritumorally or intravenously was tested using transplantable tumor models injected into mouse ears (primary tumors) or subcutaneously in flank skin (secondary tumors). Changes to the tumor microenvironment were tracked using flow cytometry while tumor-specific, CD8 T cells were identified through enzyme-linked immunospot (ELISPOT) assays. Off-target toxicity of the combination immunotherapy was assessed via serum alanine aminotransferase ELISA and histological analysis of liver sections.
    Results: The data showed that local administration of antibody therapy eliminated syngeneic murine tumors transplanted in the ear skin at a lower dose than required intravenously, and without measured hepatic toxicity. Tumor elimination was dependent on CD8 T cells and was associated with an increased percentage of CD8 T cells expressing granzyme B, KLRG1 and Eomes, and a decreased population of CD4 T cells including CD4
    Conclusions: Together, these data suggest that peritumoral immunotherapy for skin tumors offers advantages over conventional intravenous delivery, allowing antibody dose sparing, improved safety and inducing long-term systemic memory. Future clinical trials of immunotherapy for primary skin cancer should focus on peritumoral delivery of combinations of immune checkpoint antibodies.
    MeSH term(s) Animals ; Mice ; CD8-Positive T-Lymphocytes ; Immunomodulation ; Antibodies/pharmacology ; Skin Neoplasms/drug therapy ; Immunotherapy ; Tumor Microenvironment
    Chemical Substances Antibodies
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2719863-7
    ISSN 2051-1426 ; 2051-1426
    ISSN (online) 2051-1426
    ISSN 2051-1426
    DOI 10.1136/jitc-2023-007960
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Gap patterns and radiographic follow-up of newer-generation cementless total knee arthroplasty designs.

    Frazer, Abigail / Lim, Jason B T / Teeter, Matthew G / Howard, James / Vasarhelyi, Edward M / Lanting, Brent A

    Canadian journal of surgery. Journal canadien de chirurgie

    2024  Volume 67, Issue 2, Page(s) E85–E90

    Abstract: Background: Interest in cementless total knee arthroplasty (TKA) has increased with advancement of biomaterials and implant design and associated improved longevity. We sought to evaluate the gap patterns and radiolucent zones radiographically for 2 ... ...

    Abstract Background: Interest in cementless total knee arthroplasty (TKA) has increased with advancement of biomaterials and implant design and associated improved longevity. We sought to evaluate the gap patterns and radiolucent zones radiographically for 2 newer-generation cementless TKA designs.
    Methods: We retrospectively reviewed our single-institution database between January 2017 and December 2019. We identified patients with a porous keeled tibia base-plate with 4-bullet cruciform spikes and peri-apatite coated femoral component (study group 1) and patients who received a cementless porous coated femoral component and rotating platform tibia baseplate with 4 peripheral porous coated pegs around a central cone (study group 2). We identified gap patterns at 6 weeks and at 1 year or more postoperatively on radiographs, noting indications for reoperation.
    Results: We identified 228 patients in study group 1 and 41 patients in study group 2. At 1-year follow-up, we found evidence of resolved femoral gaps in 52 (72.2%) of 72 patients in study group 1 and 10 (58.8%) of 17 patients in study group 2 (
    Conclusion: The modern cementless TKA systems have varied gap patterns in postoperative radiographs, which may be attributed to the implant design. Most radiolucent gaps resolve radiographically on follow-up.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Knee ; Knee Prosthesis ; Follow-Up Studies ; Retrospective Studies ; Femur/diagnostic imaging ; Femur/surgery ; Reoperation ; Prosthesis Design ; Treatment Outcome ; Prosthesis Failure
    Language English
    Publishing date 2024-03-07
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.008223
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Involvement of the open-source community in combating the worldwide COVID-19 pandemic: a review.

    Frazer, John Scott / Shard, Amelia / Herdman, James

    Journal of medical engineering & technology

    2020  Volume 44, Issue 4, Page(s) 169–176

    Abstract: The ongoing COVID-19 pandemic is unprecedented in the modern age both due to its scale and its disruption to daily life throughout the world. Widespread social isolation and restrictions in the age of modern communicative technology, coupled with some ... ...

    Abstract The ongoing COVID-19 pandemic is unprecedented in the modern age both due to its scale and its disruption to daily life throughout the world. Widespread social isolation and restrictions in the age of modern communicative technology, coupled with some early successes for makers, have united the open-source community towards a common goal in a way not previously seen. Local hospitals and care facilities are turning to makers to print essential consumable parts, such as simple visors, while in the hardest hit areas, critical pieces of medical technology are being fabricated. While important and effective innovations are appearing almost daily, there are also some worrying trends towards hobbyists attempting manufacture of complex medical devices with little understanding of the clinical or scientific rationale behind their design. The nature of the open-source community, an area of intensive innovation, fluidity, and experimentation, jars with the exacting standards of medical device regulation. Here, we review the involvement of rapid prototyping and the open-source community in the key areas of personal protective equipment (PPE), diagnostics, critical care technology, and information acquisition and sharing, highlighting where makers and hackers have clashed with medical device regulations, and areas where the system has worked well to facilitate change.
    MeSH term(s) COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/prevention & control ; Critical Care/methods ; Humans ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Printing, Three-Dimensional
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 243092-7
    ISSN 1464-522X ; 0309-1902
    ISSN (online) 1464-522X
    ISSN 0309-1902
    DOI 10.1080/03091902.2020.1757772
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1970: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: The first assessment of the genetic diversity and structure of the endangered West Indian manatee in Cuba.

    Alvarez-Aleman, Anmari / Hunter, Margaret E / Frazer, Thomas K / Powell, James A / Alfonso, Eddy Garcia / Austin, James D

    Genetica

    2022  Volume 150, Issue 6, Page(s) 327–341

    Abstract: The coastal waters of Cuba are home to a small, endangered population of West Indian manatee, which would benefit from a comprehensive characterization of the population's genetic variation. We conducted the first genetic assessment of Cuban manatees to ... ...

    Abstract The coastal waters of Cuba are home to a small, endangered population of West Indian manatee, which would benefit from a comprehensive characterization of the population's genetic variation. We conducted the first genetic assessment of Cuban manatees to determine the extent of the population's genetic structure and characterize the neutral genetic diversity among regions within the archipelago. We genotyped 49 manatees at 18 microsatellite loci, a subset of 27 samples on 1703 single nucleotide polymorphisms (SNPs), and sequenced 59 manatees at the mitochondrial control region. The Cuba manatee population had low nuclear (microsatellites H
    MeSH term(s) Animals ; Trichechus manatus/genetics ; Cuba ; Microsatellite Repeats ; Trichechus/genetics ; Genetic Variation ; Genetics, Population
    Language English
    Publishing date 2022-10-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2165-9
    ISSN 1573-6857 ; 0016-6707
    ISSN (online) 1573-6857
    ISSN 0016-6707
    DOI 10.1007/s10709-022-00172-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.87: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: An Interpretable and Accurate Deep-Learning Diagnosis Framework Modeled With Fully and Semi-Supervised Reciprocal Learning.

    Wang, Chong / Chen, Yuanhong / Liu, Fengbei / Elliott, Michael / Kwok, Chun Fung / Pena-Solorzano, Carlos / Frazer, Helen / McCarthy, Davis James / Carneiro, Gustavo

    IEEE transactions on medical imaging

    2024  Volume 43, Issue 1, Page(s) 392–404

    Abstract: The deployment of automated deep-learning classifiers in clinical practice has the potential to streamline the diagnosis process and improve the diagnosis accuracy, but the acceptance of those classifiers relies on both their accuracy and ... ...

    Abstract The deployment of automated deep-learning classifiers in clinical practice has the potential to streamline the diagnosis process and improve the diagnosis accuracy, but the acceptance of those classifiers relies on both their accuracy and interpretability. In general, accurate deep-learning classifiers provide little model interpretability, while interpretable models do not have competitive classification accuracy. In this paper, we introduce a new deep-learning diagnosis framework, called InterNRL, that is designed to be highly accurate and interpretable. InterNRL consists of a student-teacher framework, where the student model is an interpretable prototype-based classifier (ProtoPNet) and the teacher is an accurate global image classifier (GlobalNet). The two classifiers are mutually optimised with a novel reciprocal learning paradigm in which the student ProtoPNet learns from optimal pseudo labels produced by the teacher GlobalNet, while GlobalNet learns from ProtoPNet's classification performance and pseudo labels. This reciprocal learning paradigm enables InterNRL to be flexibly optimised under both fully- and semi-supervised learning scenarios, reaching state-of-the-art classification performance in both scenarios for the tasks of breast cancer and retinal disease diagnosis. Moreover, relying on weakly-labelled training images, InterNRL also achieves superior breast cancer localisation and brain tumour segmentation results than other competing methods.
    MeSH term(s) Humans ; Female ; Deep Learning ; Breast Neoplasms ; Retina ; Retinal Diseases ; Supervised Machine Learning
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 622531-7
    ISSN 1558-254X ; 0278-0062
    ISSN (online) 1558-254X
    ISSN 0278-0062
    DOI 10.1109/TMI.2023.3306781
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2546: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top