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  1. Article ; Online: A

    Perry, Christopher J / Warren, Eleanor C / Damstra-Oddy, Joseph L / Storey, Claire / Francione, Lisa M / Annesley, Sarah J / Fisher, Paul R / Müller-Taubenberger, Annette / Williams, Robin S B

    Biochemistry and biophysics reports

    2020  Volume 22, Page(s) 100751

    Abstract: Visualizing mitochondria in ... ...

    Abstract Visualizing mitochondria in living
    Language English
    Publishing date 2020-03-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2831046-9
    ISSN 2405-5808 ; 2405-5808
    ISSN (online) 2405-5808
    ISSN 2405-5808
    DOI 10.1016/j.bbrep.2020.100751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A

    Bachert, Beth A / Biryukov, Sergei S / Chua, Jennifer / Rodriguez, Sabrina A / Toothman, Ronald G / Cote, Christopher K / Klimko, Christopher P / Hunter, Melissa / Shoe, Jennifer L / Williams, Janice A / Kuehl, Kathleen A / Biot, Fabrice V / Bozue, Joel A

    Frontiers in microbiology

    2019  Volume 10, Page(s) 1343

    Abstract: Francisella ... ...

    Abstract Francisella tularensis
    Language English
    Publishing date 2019-06-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2019.01343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: A

    Edwards, Todd L / Giri, Ayush / Hellwege, Jacklyn N / Hartmann, Katherine E / Stewart, Elizabeth A / Jeff, Janina M / Bray, Michael J / Pendergrass, Sarah A / Torstenson, Eric S / Keaton, Jacob M / Jones, Sarah H / Gogoi, Radhika P / Kuivaniemi, Helena / Jackson, Kathryn L / Kho, Abel N / Kullo, Iftikhar J / McCarty, Catherine A / Im, Hae Kyung / Pacheco, Jennifer A /
    Pathak, Jyotishman / Williams, Marc S / Tromp, Gerard / Kenny, Eimear E / Peissig, Peggy L / Denny, Joshua C / Roden, Dan M / Velez Edwards, Digna R

    Frontiers in genetics

    2019  Volume 10, Page(s) 511

    Abstract: Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion in healthcare costs each year. Although fibroid risk is heritable, genetic risk for fibroids is not well understood. We conducted a two-stage case-control meta- ... ...

    Abstract Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion in healthcare costs each year. Although fibroid risk is heritable, genetic risk for fibroids is not well understood. We conducted a two-stage case-control meta-analysis of genetic variants in European and African ancestry women with and without fibroids classified by a previously published algorithm requiring pelvic imaging or confirmed diagnosis. Women from seven electronic Medical Records and Genomics (eMERGE) network sites (3,704 imaging-confirmed cases and 5,591 imaging-confirmed controls) and women of African and European ancestry from UK Biobank (UKB, 5,772 cases and 61,457 controls) were included in the discovery genome-wide association study (GWAS) meta-analysis. Variants showing evidence of association in Stage I GWAS (
    Language English
    Publishing date 2019-06-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2019.00511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A

    McNeely, Patrick M / Naranjo, Andrea N / Forsten-Williams, Kimberly / Robinson, Anne Skaja

    SLAS discovery : advancing life sciences R & D

    2016  Volume 22, Issue 2, Page(s) 166–175

    Abstract: Ligand binding plays a fundamental role in stimulating the downstream signaling of membrane receptors. Here, ligand-binding kinetics of the full-length human adenosine ... ...

    Abstract Ligand binding plays a fundamental role in stimulating the downstream signaling of membrane receptors. Here, ligand-binding kinetics of the full-length human adenosine A
    MeSH term(s) Binding Sites ; Binding, Competitive ; Fluorescence Polarization ; Humans ; Kinetics ; Ligands ; Protein Binding ; Protein Transport/genetics ; Receptor, Adenosine A2A/chemistry ; Receptor, Adenosine A2A/metabolism
    Chemical Substances ADORA2A protein, human ; Ligands ; Receptor, Adenosine A2A
    Language English
    Publishing date 2016-09-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2885123-7
    ISSN 2472-5560 ; 2472-5552
    ISSN (online) 2472-5560
    ISSN 2472-5552
    DOI 10.1177/1087057116667256
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4911: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Book: Fundamental Concepts and Skills for Nursing - Revised Reprint

    Williams, Patricia A.

    2022  

    Size 968 p.
    Publisher Elsevier - Health Sciences Division
    Document type Book
    Note PDA Manuell_15
    Format 218 x 283 x 37
    ISBN 9780323847667 ; 0323847668
    Database PDA

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    Order for free: Patron-Driven-Acquisition (PDA)

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  6. Book ; Online ; E-Book: Toxicology of nanoparticles and nanomaterials in human, terrestrial and aquatic systems

    Williams, Marc A.

    2022  

    Abstract: The focus of this book is on human health risk assessment in the context of nanoparticle exposures. The book is authored by a highly-qualified team of subject matter experts, guided by editors that each has at least 25 years or more of laboratory ... ...

    Author's details edited by Marc A. Williams
    Abstract "The focus of this book is on human health risk assessment in the context of nanoparticle exposures. The book is authored by a highly-qualified team of subject matter experts, guided by editors that each has at least 25 years or more of laboratory investigative experience and publication in the fields covered in this book. The book is split into four sections. The first section is an introduction which includes an overview of the field. The second section details Health Effects of Nano -- Evidence from Animal Models and In Vitro Systems. The third covers Health Effects of Nano -- Evidence from Human Exposures, Environmental Assessments, and Disasters. The book concludes with topics on Emerging Applications, Ecotoxicology of Nanotechnology, Risk Assessment, and Regulation".
    Keywords Nanoparticles/Toxicology ; Nanoparticles/Health aspects ; Nanoparticles/Environmental aspects
    Subject code 615.1901
    Language English
    Size 1 online resource (xxiv, 466 pages) :, illustrations (chiefly color)
    Publisher Wiley
    Publishing place Hoboken, New Jersey ; Chichester, West Sussex, England
    Document type Book ; Online ; E-Book
    Note Description based upon print version of record.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-1-119-31632-9 ; 9781119316374 ; 978-1-119-31635-0 ; 1-119-31635-9 ; 1-119-31632-4 ; 1-119-31633-2 ; 1119316375 ; 978-1-119-31633-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Book: Appetite and Its Discontents

    Williams, Elizabeth A

    Science, Medicine, and the Urge to Eat, 1750-1950

    2020  

    Author's details Elizabeth A. Williams is professor emerita of history at Oklahoma State University
    Size 416 p.
    Publisher University of Chicago Press
    Document type Book
    Note PDA Manuell_5
    Format 154 x 231 x 28
    ISBN 9780226693040 ; 022669304X
    Database PDA

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    Order for free: Patron-Driven-Acquisition (PDA)

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  8. Book ; Online ; E-Book: Exercise and respiratory diseases in paediatrics

    Williams, Craig A. / Oades, Patrick J.

    (Routledge research in paediatric sport and exercise science series)

    2022  

    Author's details edited by Craig A. Williams and Patrick J. Oades
    Series title Routledge research in paediatric sport and exercise science series
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (227 Seiten), Illustrationen
    Publisher Routledge
    Publishing place New York
    Publishing country United States
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021015428
    ISBN 978-1-00-044871-9 ; 9780367896171 ; 1-00-044871-1 ; 0367896176
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Book ; Online ; E-Book: Successful change management in health care

    Chowthi-Williams, Annette / Davis, Geraldine

    being emotionally and cognitively ready

    2022  

    Abstract: Change is frequent in healthcare, yet change management is often far from perfect. This book considers the complexity of change within large organisations, explores existing models of change, and emphasises the vital role of emotional and cognitive ... ...

    Author's details Annette Chowthi-Williams and Geraldine Davis
    Abstract Change is frequent in healthcare, yet change management is often far from perfect. This book considers the complexity of change within large organisations, explores existing models of change, and emphasises the vital role of emotional and cognitive readiness in successful change management. Despite the plethora of organisational change management approaches used in healthcare, the success rate of change in organisations can be as low as 30%. New thinking about change management is required to improve success in service development, improvement and innovation. Arguing that emotional and cognitive readiness for change requires engagement with the people involved, and a thorough understanding of areas of friction and potential challenge, this book also delves into the neglected issue of emotion, examining emotional labour and emotion and change. It investigates how human emotion can be incorporated into change management models, alongside and intertwined with cognitive approaches, to support effective change. Using the NHS as a central case study, this book incorporates examples of actual change from a range of healthcare settings from acute to primary care, enabling readers to see how change management models can be adapted and utilised in practice. This is an essential read for students, as future change leaders, and practitioners and managers leading and managing change in healthcare.
    Keywords Health facilities/Administration ; Health services administration
    Subject code 362.1068
    Language English
    Size 1 online resource (207 pages)
    Edition First edition.
    Publisher Routledge
    Publishing place Abingdon
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-312839-4 ; 1-000-54711-6 ; 1-000-54709-4 ; 1-003-12839-4 ; 0-367-65213-7 ; 0-367-65215-3 ; 978-1-00-312839-7 ; 978-1-000-54711-5 ; 978-1-000-54709-2 ; 978-1-003-12839-7 ; 978-0-367-65213-5 ; 978-0-367-65215-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Multiomics data integration, limitations, and prospects to reveal the metabolic activity of the coral holobiont.

    Williams, Amanda

    FEMS microbiology ecology

    2024  

    Abstract: Since their radiation in the Middle Triassic period ∼ 240 million years ago, stony corals have survived past climate fluctuations and five mass extinctions. Their long-term survival underscores the inherent resilience of corals, particularly when ... ...

    Abstract Since their radiation in the Middle Triassic period ∼ 240 million years ago, stony corals have survived past climate fluctuations and five mass extinctions. Their long-term survival underscores the inherent resilience of corals, particularly when considering the nutrient-poor marine environments in which they have thrived. However, coral bleaching has emerged as a global threat to coral survival, requiring rapid advancements in coral research to understand holobiont stress responses and allow for interventions before extensive bleaching occurs. This review encompasses the potential, as well as the limits, of multiomics data applications when applied to the coral holobiont. Synopses for how different omics tools have been applied to date and their current restrictions are discussed, in addition to ways these restrictions may be overcome, such as recruiting new technology to studies, utilizing novel bioinformatics approaches, and generally integrating omics data. Lastly, this review presents considerations for the design of holobiont multiomics studies to support lab-to-field advancements of coral stress marker monitoring systems. Although much of the bleaching mechanism has eluded investigation to date, multiomic studies have already produced key findings regarding the holobiont's stress response, and have the potential to advance the field further.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 283722-5
    ISSN 1574-6941 ; 0168-6496
    ISSN (online) 1574-6941
    ISSN 0168-6496
    DOI 10.1093/femsec/fiae058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2967: Show issues Location:
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